CO4820440A1 - Composiciones que contienen adenovirus recombinantes concentrados - Google Patents

Composiciones que contienen adenovirus recombinantes concentrados

Info

Publication number
CO4820440A1
CO4820440A1 CO99009282A CO99009282A CO4820440A1 CO 4820440 A1 CO4820440 A1 CO 4820440A1 CO 99009282 A CO99009282 A CO 99009282A CO 99009282 A CO99009282 A CO 99009282A CO 4820440 A1 CO4820440 A1 CO 4820440A1
Authority
CO
Colombia
Prior art keywords
virus
preparation
compositions containing
recombinant adenoviruses
containing concentrated
Prior art date
Application number
CO99009282A
Other languages
English (en)
Inventor
Andreas Frei
Henry K H Kwan
Varda E Sandweiss
Gary J Vellekamp
Pui-Ho Yuen
Laureano L Bondoc
Porter Iv Jr Frederick William
Tang John Chu-Tay
Peter Ihnat
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of CO4820440A1 publication Critical patent/CO4820440A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material

Abstract

Se da a conocer una composición que contiene virus enuna formulación que contiene un polihidroxi hidrocarburo regulada para mantener un pH en el intervalo de aproximadamente 7 a aproximadamente 8,5 a una temperatura en el orden de aproximadamente 2°C a 27°C. Se dan a conocer también métodos para concentrar y purificar los preparados de virus.Un método para concentrar un preparado de virus que consiste en:a). Adicionar un polihidroxi hidrocarburo a un preparado de virus hasta una concentración final de polihidroxi hidrocarburo de aproximadamente 20% o más.b). someter el preparado de virus a un proceso de filtración en el cual la concentración de virus se incrementa aplicando presión al preparado de modo tal que se elimine diluyente del preparado de virus a través de un filtro mientras que el virus es retenido.Un método para purificar una preparación de virus.
CO99009282A 1998-02-17 1999-02-16 Composiciones que contienen adenovirus recombinantes concentrados CO4820440A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2446298A 1998-02-17 1998-02-17
US7964398A 1998-05-15 1998-05-15

Publications (1)

Publication Number Publication Date
CO4820440A1 true CO4820440A1 (es) 1999-07-28

Family

ID=26698472

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99009282A CO4820440A1 (es) 1998-02-17 1999-02-16 Composiciones que contienen adenovirus recombinantes concentrados

Country Status (25)

Country Link
EP (4) EP1526173B1 (es)
JP (3) JP4358434B2 (es)
KR (5) KR100918187B1 (es)
CN (2) CN101164623B (es)
AR (3) AR020054A1 (es)
AT (3) ATE341614T1 (es)
AU (1) AU757976B2 (es)
BR (1) BR9908015A (es)
CA (2) CA2320419C (es)
CO (1) CO4820440A1 (es)
DE (3) DE69933433T2 (es)
DK (1) DK1054955T3 (es)
ES (2) ES2290613T3 (es)
HK (3) HK1073481A1 (es)
HU (1) HU226015B1 (es)
ID (1) ID28298A (es)
IL (2) IL137510A0 (es)
MY (1) MY141641A (es)
NO (1) NO20004104L (es)
PE (1) PE20000265A1 (es)
PL (1) PL197747B1 (es)
PT (1) PT1054955E (es)
SK (1) SK11842000A3 (es)
TW (1) TWI232107B (es)
WO (1) WO1999041416A2 (es)

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US8932607B2 (en) 2012-03-12 2015-01-13 Crucell Holland B.V. Batches of recombinant adenovirus with altered terminal ends
KR102044051B1 (ko) 2012-03-12 2019-11-12 얀센 백신스 앤드 프리벤션 비.브이. 터미널 말단이 변경된 재조합 아데노바이러스의 배치
US9125870B2 (en) 2012-03-22 2015-09-08 Crucell Holland B.V. Vaccine against RSV
WO2013139916A1 (en) 2012-03-22 2013-09-26 Crucell Holland B.V. Vaccine against rsv
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US10294279B2 (en) 2013-06-17 2019-05-21 Janssen Vaccines & Prevention B.V. Stabilized soluble pre-fusion RSV F polypeptides
KR20170004966A (ko) * 2014-05-28 2017-01-11 에이전시 포 사이언스, 테크놀로지 앤드 리서치 바이러스 감소 방법
PL3283634T3 (pl) 2015-04-14 2019-10-31 Janssen Vaccines & Prevention Bv Rekombinowany adenowirus eksprymujący dwa transgeny z dwukierunkowym promotorem
BR112017027448A2 (pt) 2015-07-07 2018-09-04 Janssen Vaccines & Prevention Bv vacina contra rsv
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US10744196B2 (en) 2016-07-14 2020-08-18 Janssen Vaccines & Prevention B.V. HPV vaccines
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US11229692B2 (en) 2017-05-17 2022-01-25 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against RSV infection
WO2019021305A1 (en) * 2017-07-24 2019-01-31 Ella Foundation VACCINE AGAINST FOOT AND MOUTH DISEASE
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JP2024509756A (ja) 2021-02-19 2024-03-05 ヤンセン ファッシンズ アンド プリベンション ベーフェー 安定化された融合前ｒｓｖ ｆｂ抗原
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Also Published As

Publication number Publication date
AR063314A2 (es) 2009-01-21
ES2272053T3 (es) 2007-04-16
EP1526173A2 (en) 2005-04-27
WO1999041416A2 (en) 1999-08-19
KR20090127947A (ko) 2009-12-14
PL342847A1 (en) 2001-07-16
AR020054A1 (es) 2002-04-10
SK11842000A3 (sk) 2001-05-10
HK1073481A1 (en) 2005-10-07
AU2653899A (en) 1999-08-30
CA2320419C (en) 2011-02-08
PE20000265A1 (es) 2000-04-25
DE69933433D1 (de) 2006-11-16
KR100862169B1 (ko) 2008-10-09
DE69936948D1 (de) 2007-10-04
JP2010213727A (ja) 2010-09-30
HK1028416A1 (en) 2001-02-16
JP2006166925A (ja) 2006-06-29
AU757976B2 (en) 2003-03-13
EP1054955B1 (en) 2006-10-04
EP1054955A2 (en) 2000-11-29
EP1741777A1 (en) 2007-01-10
KR20090038927A (ko) 2009-04-21
KR20080065615A (ko) 2008-07-14
KR100912362B1 (ko) 2009-08-19
EP1526173A3 (en) 2005-08-10
CA2723040A1 (en) 1999-08-19
DE69942708D1 (de) 2010-10-07
IL137510A (en) 2012-10-31
ATE371020T1 (de) 2007-09-15
EP1526174A3 (en) 2005-08-31
CN100374551C (zh) 2008-03-12
HK1097413A1 (en) 2007-06-22
CN101164623A (zh) 2008-04-23
IL137510A0 (en) 2001-07-24
WO1999041416A3 (en) 1999-11-18
NO20004104L (no) 2000-10-17
DE69936948T2 (de) 2008-05-15
KR20080065614A (ko) 2008-07-14
TWI232107B (en) 2005-05-11
DE69933433T2 (de) 2007-08-23
CA2320419A1 (en) 1999-08-19
KR100918187B1 (ko) 2009-09-22
HUP0100670A3 (en) 2003-10-28
CN1297478A (zh) 2001-05-30
ES2290613T3 (es) 2008-02-16
EP1526174B1 (en) 2007-08-22
ID28298A (id) 2001-05-10
KR100991683B1 (ko) 2010-11-04
PT1054955E (pt) 2007-01-31
ATE478945T1 (de) 2010-09-15
KR101018992B1 (ko) 2011-03-07
JP2002503484A (ja) 2002-02-05
HU226015B1 (en) 2008-02-28
MY141641A (en) 2010-05-31
ATE341614T1 (de) 2006-10-15
EP1741777B1 (en) 2010-08-25
KR20010072547A (ko) 2001-07-31
CN101164623B (zh) 2012-11-14
EP1526173B1 (en) 2012-11-21
NO20004104D0 (no) 2000-08-16
DK1054955T3 (da) 2007-01-15
HUP0100670A2 (hu) 2001-06-28
JP4358434B2 (ja) 2009-11-04
PL197747B1 (pl) 2008-04-30
EP1526174A2 (en) 2005-04-27
BR9908015A (pt) 2001-04-24
AR063315A2 (es) 2009-01-21

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