DK0974366T3 - Orale, farmaceutiske præparater med nedsat bitterhed ved maskering - Google Patents

Orale, farmaceutiske præparater med nedsat bitterhed ved maskering

Info

Publication number
DK0974366T3
DK0974366T3 DK98911029T DK98911029T DK0974366T3 DK 0974366 T3 DK0974366 T3 DK 0974366T3 DK 98911029 T DK98911029 T DK 98911029T DK 98911029 T DK98911029 T DK 98911029T DK 0974366 T3 DK0974366 T3 DK 0974366T3
Authority
DK
Denmark
Prior art keywords
masking
pharmaceutical preparations
oral pharmaceutical
reduced bitterness
unpleasant
Prior art date
Application number
DK98911029T
Other languages
Danish (da)
English (en)
Inventor
Koji Ukai
Yasuyuki Suzuki
Tsutomu Harada
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of DK0974366T3 publication Critical patent/DK0974366T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK98911029T 1997-03-28 1998-03-26 Orale, farmaceutiske præparater med nedsat bitterhed ved maskering DK0974366T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP7856897 1997-03-28
JP34326597 1997-12-12
PCT/JP1998/001360 WO1998043675A1 (fr) 1997-03-28 1998-03-26 Preparations pharmaceutiques orales dont on a reduit l'amertume au moyen d'un masquant

Publications (1)

Publication Number Publication Date
DK0974366T3 true DK0974366T3 (da) 2007-01-29

Family

ID=26419628

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98911029T DK0974366T3 (da) 1997-03-28 1998-03-26 Orale, farmaceutiske præparater med nedsat bitterhed ved maskering

Country Status (9)

Country Link
US (1) US7727552B1 (de)
EP (1) EP0974366B1 (de)
JP (1) JP5053228B2 (de)
KR (1) KR100693266B1 (de)
AT (1) ATE342735T1 (de)
DE (1) DE69836207T2 (de)
DK (1) DK0974366T3 (de)
ES (1) ES2273409T3 (de)
WO (1) WO1998043675A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100746753B1 (ko) * 1998-08-28 2007-08-06 에자이 알앤드디 매니지먼트 가부시키가이샤 고미 등을 경감한 의약조성물
KR20000046974A (ko) * 1998-12-31 2000-07-25 윤재승 아세글루타미드 알루미늄의 경구 투여용 제제 조성물ㅇ
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) * 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6699315B2 (en) 2000-11-28 2004-03-02 Fmc Corporation Edible PGA coating composition
WO2002043704A1 (en) * 2000-12-01 2002-06-06 Kyowa Hakko Kogyo Co., Ltd. Composition improved in solubility or oral absorbability
WO2003097102A1 (fr) * 2002-05-22 2003-11-27 Shionogi & Co., Ltd. Preparation pharmaceutique dans laquelle la propriete de dissolution d'un medicament faiblement soluble dans l'eau est amelioree
CA2552221A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Donepezil formulations
PL2609812T3 (pl) 2007-12-20 2019-02-28 N.V. Nutricia Ciekły produkt zawierający nukleotydy/nukleozydy
US20110124577A1 (en) * 2008-07-30 2011-05-26 Suntory Holdings Limited Preparation for oral administration comprises quercetin glycoside and a water-based solvent extract of cartilage containing chondroitin sulfate
US8715715B2 (en) 2008-11-03 2014-05-06 Nal Pharmaceuticals Ltd. Dosage form for insertion into the mouth
PL2243473T3 (pl) 2009-04-17 2019-01-31 Hexal Ag Tabletki zawierające środek maskujący smak
EP2366378A1 (de) 2010-03-01 2011-09-21 Dexcel Pharma Technologies Ltd. Donepezilformulierungen mit verzögerter Freisetzung
JP5491943B2 (ja) * 2010-04-28 2014-05-14 ゼリア新薬工業株式会社 ビタミンｂ１類含有経口ゼリー剤
KR20140007798A (ko) 2010-09-13 2014-01-20 베브-알엑스, 인코포레이티드 이취 차폐제를 포함하는 수성 약물 전달 시스템
EP2468254A1 (de) 2010-12-15 2012-06-27 Hexal AG Oral zerfallende Tablette mit Geschmacksunterdrückungseffekt
BR112013015986A2 (pt) * 2010-12-23 2018-07-10 Colgate Palmolive Co composições para cuidados orais.
CN104703487B (zh) * 2012-10-25 2017-05-17 雀巢产品技术援助有限公司 被包封的苦味肽、包封苦味肽的方法以及包含被包封的苦味肽的营养组合物
TW201540301A (zh) 2013-08-16 2015-11-01 Takeda Gmbh 以ｐｄｅ４抑制劑治療認知損傷
CN106727272A (zh) * 2016-12-08 2017-05-31 星康桥医药科技（南京）有限公司 一种漱口制剂及漱口方法
JP7057286B2 (ja) 2016-12-28 2022-04-19 富士フイルム富山化学株式会社 医薬組成物
KR20200064951A (ko) 2018-11-29 2020-06-08 동국제약 주식회사 약리학적 활성 성분을 함유한 구강붕해필름 및 그의 제조방법
EP4284347A1 (de) 2021-01-28 2023-12-06 Galvita AG Feste pharmazeutische zusammensetzungen und verfahren zur herstellung davon
EP4311543A1 (de) 2022-07-27 2024-01-31 Galvita AG Verfahren zum laden von invertierten vorlagenträgern

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5176413A (ja) 1974-12-25 1976-07-02 Toyo Jozo Kk Hifukuzainoseizoho
JPS5476818A (en) 1977-11-25 1979-06-19 Egyt Gyogyszervegyeszeti Gyar Pharmaceutical composition having prolonged effect and production thereof
JPS5565741A (en) * 1978-11-10 1980-05-17 Tokico Ltd Shock absorber
GB2122892B (en) 1982-07-02 1986-01-29 Squibb & Sons Inc Nystantin pastille formulation
JPS60204712A (ja) 1984-03-29 1985-10-16 Ss Pharmaceut Co Ltd 塩酸メクリジンの安定化液状組成物
JPS61130239A (ja) 1984-11-30 1986-06-18 Dai Ichi Seiyaku Co Ltd 複合体
US5286489A (en) * 1985-08-26 1994-02-15 The Procter & Gamble Company Taste masking compositions
JPS63309150A (ja) * 1987-06-11 1988-12-16 San Ei Chem Ind Ltd 即席ゲル状物の製造法
JPH0717498B2 (ja) 1989-05-31 1995-03-01 興和株式会社 鎮咳去痰ソフトカプセル剤
US5084278A (en) 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
US5013557A (en) * 1989-10-03 1991-05-07 Warner-Lambert Company Taste masking compositions comprising spray dried microcapsules containing sucralfate and methods for preparing same
US5077053A (en) 1990-02-12 1991-12-31 Warner-Lambert Company Zein as a moisture barrier for sugarless edible compositions and method for preparing same
JPH03287535A (ja) 1990-03-31 1991-12-18 Bairon Boeki Kk プラノプロフェン水溶液
JPH0418015A (ja) 1990-05-10 1992-01-22 Fujikawa Kk 安定なフマル酸クレマスチン水溶液
JP2508547B2 (ja) * 1991-01-08 1996-06-19 株式会社紀文食品 苦味低減方法及び苦味低減化組成物
JP3073544B2 (ja) * 1991-02-18 2000-08-07 三栄源エフ・エフ・アイ株式会社 塩化カリウムの脱苦味方法
JPH04282312A (ja) 1991-03-08 1992-10-07 Eisai Co Ltd コ−ティング層を有する粒状物
JP2508555B2 (ja) 1991-05-24 1996-06-19 株式会社紀文食品 苦味低減方法
CA2068402C (en) 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
DE4122217C2 (de) 1991-07-04 1997-02-13 Merz & Co Gmbh & Co Verfahren zur Herstellung mechanisch stabiler, gut zerfallender Komprimate aus kleinen wirkstoffhaltigen Formkörpern
JPH05163154A (ja) 1991-12-13 1993-06-29 Kanebo Ltd 経口液剤
KR100256147B1 (ko) 1991-12-24 2000-08-01 오노다 마사요시 구강내 붕해성 제제 및 이의 제조방법
ATE216577T1 (de) 1992-01-29 2002-05-15 Takeda Chemical Industries Ltd Schnellösliche tablette und ihre herstellung
JPH06218028A (ja) 1992-10-02 1994-08-09 Eisai Co Ltd 湿製錠の成型方法とその装置及び湿製錠
WO1994013257A1 (en) 1992-12-16 1994-06-23 Creative Products Resource Associates, Ltd. Occlusive/semi-occlusive lotion for treatment of a skin disease or disorder
CA2122286A1 (en) * 1993-04-28 1994-10-29 Hiroshi Matoba Solid preparation and its production
DE69411181T2 (de) 1993-10-01 1999-02-18 Kao Corp., Tokio/Tokyo Gegen ultraviolettstrahlung schützende feine kompositteilchen, verfahren zur herstellung derselben und kosmetika
US5576014A (en) 1994-01-31 1996-11-19 Yamanouchi Pharmaceutical Co., Ltd Intrabuccally dissolving compressed moldings and production process thereof
JPH07267850A (ja) 1994-03-28 1995-10-17 Eisai Co Ltd 不快味を防止した医薬組成物及びその製造方法
JP3187657B2 (ja) 1994-07-08 2001-07-11 株式会社三共製作所 錠剤製造方法およびその装置
US5672364A (en) 1994-07-07 1997-09-30 Sankyo Seisakusho Co. & Eisai Co., Ltd. Apparatus for manufacturing tablets
DE4432757A1 (de) 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
US5656284A (en) * 1995-04-24 1997-08-12 Balkin; Michael S. Oral transmucosal delivery tablet and method of making it
JPH08333245A (ja) 1995-06-07 1996-12-17 Taisho Pharmaceut Co Ltd イブプロフェン懸濁液剤
SK74396A3 (en) 1995-06-13 1997-04-09 American Home Prod Organoleptically acceptable oral pharmaceutical compositions
TW442287B (en) 1995-06-13 2001-06-23 American Home Produits Corp Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)
JPH0948726A (ja) 1995-08-07 1997-02-18 Tanabe Seiyaku Co Ltd 口腔内速崩壊性製剤およびその製法
JPH09143100A (ja) 1995-11-20 1997-06-03 Sumitomo Pharmaceut Co Ltd 服用感の改善された固形製剤
US6214386B1 (en) 1995-11-22 2001-04-10 Recordati, S.A. Prompt-release oral pharmaceutical compositions for extemporaneous suspensions
US5612026A (en) * 1996-01-25 1997-03-18 The Procter & Gamble Company Cholesterol lowering drink mix compositons
JPH103629A (ja) 1996-06-14 1998-01-06 Asahi Komagu Kk 薄膜磁気ヘッドスライダーの製造方法
ATE291930T1 (de) 1996-07-12 2005-04-15 Daiichi Seiyaku Co Schnell zerfallende, druckgeformte materialien sowie prozess zu deren herstellung
US5763449A (en) 1996-08-07 1998-06-09 Ascent Pediatrics, Inc. Pleasant-tasting aqueous liquid composition of a bitter-tasting drug
JPH10114683A (ja) 1996-10-11 1998-05-06 Kobayashi Seiyaku Kogyo Kk 非ステロイド性解熱鎮痛消炎剤を含む固形製剤及びその製造方法
US5962535A (en) 1997-01-17 1999-10-05 Takeda Chemical Industries, Ltd. Composition for alzheimer's disease
JP4234666B2 (ja) 1997-03-28 2009-03-04 エーザイ・アール・アンド・ディー・マネジメント株式会社 苦味等を隠蔽した経口薬剤
JP3770518B2 (ja) 1997-03-28 2006-04-26 エーザイ株式会社 苦味等を隠蔽した経口薬剤
TW580397B (en) 1997-05-27 2004-03-21 Takeda Chemical Industries Ltd Solid preparation
JP3797764B2 (ja) 1997-10-01 2006-07-19 エーザイ株式会社 光安定化組成物
TW527195B (en) 1997-10-09 2003-04-11 Ssp Co Ltd Fast-soluble solid pharmaceutical combinations
JPH11199517A (ja) 1997-10-31 1999-07-27 Meiji Seika Kaisha Ltd 口腔内速崩壊性錠剤
US6368625B1 (en) 1998-08-12 2002-04-09 Cima Labs Inc. Orally disintegrable tablet forming a viscous slurry
KR100746753B1 (ko) 1998-08-28 2007-08-06 에자이 알앤드디 매니지먼트 가부시키가이샤 고미 등을 경감한 의약조성물
US6743443B1 (en) 1998-10-05 2004-06-01 Eisai Co., Ltd. Tablets immediately disintegrating in the oral cavity
AU1453600A (en) 1998-11-04 2000-05-22 Mcneil-Ppc, Inc. Solid oral dosage forms containing alginic acid and famotidine
US6656492B2 (en) 2000-06-30 2003-12-02 Yamanouchi Pharmaceutical Co., Ltd. Quick disintegrating tablet in buccal cavity and manufacturing method thereof

Also Published As

Publication number Publication date
EP0974366A1 (de) 2000-01-26
JP2009051855A (ja) 2009-03-12
WO1998043675A1 (fr) 1998-10-08
US7727552B1 (en) 2010-06-01
EP0974366B1 (de) 2006-10-18
DE69836207T2 (de) 2007-08-30
EP0974366A4 (de) 2003-03-26
ATE342735T1 (de) 2006-11-15
DE69836207D1 (de) 2006-11-30
ES2273409T3 (es) 2007-05-01
JP5053228B2 (ja) 2012-10-17
KR100693266B1 (ko) 2007-03-27
KR20010005510A (ko) 2001-01-15

Similar Documents

Publication Publication Date Title
DK0974366T3 (da) Orale, farmaceutiske præparater med nedsat bitterhed ved maskering
ATE109145T1 (de) Heterozyklische acylaminothiazolderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen.
DZ2887A1 (fr) Dérivés d'azétidine, leur préparation et les médicaments les contenant.
ATE188471T1 (de) Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammensetzung
DE69427472D1 (de) Arzneimittel mit kontrollierter Wirkstoffabgabe
DE3580616D1 (de) Mitomycinderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen.
NL1000565C2 (nl) Complex van een insuline-analoog en protamine, dit complex bevattende farmaceutische formuleringen en bereidingswerkwijzen daarvan.
ATE67930T1 (de) Wirkstofftraeger und diesen enthaltende arzneimittel.
FI943570A0 (fi) 1-bentseenisulfonyyli-1,3-dihydroindol-2-onijohdannaisia, niiden valmistus ja niitä sisältäviä lääkeaineita
DE69630145D1 (de) Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen
DE69815008D1 (de) Alfa-substituierte Phenylpropionsäurederivate und diese enthaltende Arzneimittel
DE69816471D1 (de) Pyrimidinon verbindungen und diese enthaltende pharmazeutische zusammenstellungen
DE68912232D1 (de) Konjugate zytotoxischer Arzneimittel.
ZA985406B (en) Pyrimidine-2,4,6-trione derivatives, processes for their production and pharmaceutical preparations containing these compounds.
NO20012047L (no) Medikamentavleveringssystem, spesielt for avlevering av progestiner og östrogener
DE69014351D1 (de) Pyridincarbonsäureamid-Derivate und diese enthaltende pharmazeutische Zusammensetzungen.
HK1027563A1 (en) Novel 2-(iminomethyl) amino-phenyl derivatives, preparation, application as medicines and pharmaceutical compositions containing same.
DE69131714D1 (de) Cephalosporine und ihre homologen, zubereitungen und pharmazeutsiche präparate
ATE297935T1 (de) 2-(iminomethyl)aminophenyl-derivate, deren herstellung, verwendung als medikamente und diese enthaltende pharmazeutische zubereitungen
HK1048986A1 (en) 2'-Substituted 1,1'-iphenyl-2-carbonamides, methodfor the production thereof, use thereof as medicament and pharmaceutical preparations containing said compounds.
HK1015789A1 (en) Propanolamine derivatives, processes for their preparation, pharmaceuticals comprising these compounds, and their use.
ATE193533T1 (de) Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen
HUP9903353A3 (en) 7alpha-(methyl-amino-pentyl)-estratrienes, pharmaceutical preparations which contain said 7alpha-(5-methylaminopentyl) -estratrienes and use thereof for production of drugs
FR2675802B1 (fr) Antiserotonines, leur preparation et les medicaments les contenant.
DE68901859D1 (de) 2-benzothiazolamin-derivate enthaltende arzneimittel, verbindungen und ihre herstellung.