DK0970073T3 - Fremgangsmåde til fremstilling af eprosartan - Google Patents

Fremgangsmåde til fremstilling af eprosartan

Info

Publication number
DK0970073T3
DK0970073T3 DK98906229T DK98906229T DK0970073T3 DK 0970073 T3 DK0970073 T3 DK 0970073T3 DK 98906229 T DK98906229 T DK 98906229T DK 98906229 T DK98906229 T DK 98906229T DK 0970073 T3 DK0970073 T3 DK 0970073T3
Authority
DK
Denmark
Prior art keywords
eprosartan
preparation
Prior art date
Application number
DK98906229T
Other languages
Danish (da)
English (en)
Inventor
Joseph Robert Flisak
Li Liu
Clifford S Labaw
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of DK0970073T3 publication Critical patent/DK0970073T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
DK98906229T 1997-02-14 1998-02-13 Fremgangsmåde til fremstilling af eprosartan DK0970073T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3819597P 1997-02-14 1997-02-14
PCT/US1998/002412 WO1998035963A1 (en) 1997-02-14 1998-02-13 Process for preparing eprosartan

Publications (1)

Publication Number Publication Date
DK0970073T3 true DK0970073T3 (da) 2005-02-21

Family

ID=21898583

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98906229T DK0970073T3 (da) 1997-02-14 1998-02-13 Fremgangsmåde til fremstilling af eprosartan

Country Status (41)

Country Link
US (1) US6172237B1 (zh)
EP (1) EP0970073B1 (zh)
JP (1) JP4537499B2 (zh)
KR (1) KR100573638B1 (zh)
CN (1) CN1085208C (zh)
AP (1) AP1128A (zh)
AR (1) AR011125A1 (zh)
AT (1) ATE280765T1 (zh)
AU (1) AU730383B2 (zh)
BG (1) BG63804B1 (zh)
BR (1) BR9808664A (zh)
CA (1) CA2281708C (zh)
CO (1) CO4950550A1 (zh)
CY (1) CY2555B1 (zh)
CZ (1) CZ296349B6 (zh)
DE (1) DE69827240T2 (zh)
DK (1) DK0970073T3 (zh)
EA (1) EA001659B1 (zh)
EG (1) EG23935A (zh)
ES (1) ES2231963T3 (zh)
HU (1) HU228781B1 (zh)
ID (1) ID23181A (zh)
IL (1) IL131309A (zh)
IN (2) IN187999B (zh)
MA (1) MA24470A1 (zh)
MY (1) MY118704A (zh)
NO (1) NO317194B1 (zh)
NZ (1) NZ337180A (zh)
OA (1) OA11146A (zh)
PE (1) PE59299A1 (zh)
PL (1) PL192838B1 (zh)
PT (1) PT970073E (zh)
RO (1) RO119719B1 (zh)
SA (1) SA98190082B1 (zh)
SI (1) SI0970073T1 (zh)
SK (1) SK285036B6 (zh)
TR (1) TR199901936T2 (zh)
TW (1) TW399050B (zh)
UA (1) UA54487C2 (zh)
WO (1) WO1998035963A1 (zh)
ZA (1) ZA981207B (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100137613A1 (en) * 2006-12-27 2010-06-03 Hetero Drugs Limited Process for eprosartan
EP2295430A3 (en) * 2007-07-25 2011-08-03 Hetero Drugs Limited Crystalline solid of eprosartan acetate
WO2009013760A2 (en) * 2007-07-25 2009-01-29 Hetero Drugs Limited Eprosartan mesylate crystalline particles and a process for preparing pure eprosartan
WO2009084028A2 (en) * 2007-12-03 2009-07-09 Neuland Laboratories Ltd Improved process for manufacturing anhydrous (e)-3-[2-butyl-1- {(4-carboxyphenyl) methyl}-1h-imidazole-5-yl]-(thiophen-2- ylmethyl)prop-2-enoic acid methane sulfonate
CN101215284B (zh) * 2007-12-31 2010-10-13 浙江华海药业股份有限公司 一种改进的依普罗沙坦的制备方法
US20110054186A1 (en) * 2008-03-31 2011-03-03 Hetero Research Foundation Process for eprosartan intermediate
WO2010023688A2 (en) * 2008-08-25 2010-03-04 Matrix Laboratories Limited An improved process for the preparation of eprosartan
WO2011004384A2 (en) 2009-06-05 2011-01-13 Glochem Industries Limited Process for the preparation of eprosartan
WO2011051975A1 (en) 2009-10-30 2011-05-05 Matrix Laboratories Ltd An improved process for the preparation of pure eprosartanand its pharmaceutical acceptable salts

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5185351A (en) * 1989-06-14 1993-02-09 Smithkline Beecham Corporation Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
NZ239161A (en) * 1990-07-31 1994-01-26 Smithkline Beecham Corp Substituted [1h-imidazol-5-yl] alkanoic acid derivatives; medicaments,
EP0563238B1 (en) * 1990-12-14 2002-05-22 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
US5395847A (en) * 1993-12-02 1995-03-07 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
PL185858B1 (pl) * 1994-05-20 2003-08-29 Smithkline Beecham Corp Związek addycyjny kwasu 4-[(2-n-butylo-5-formylo-1Związek addycyjny kwasu 4-[(2-n-butylo-5-formylo-1H-imidazol-1-ilo)metylo]benzoesowego z wodorosiarcH-imidazol-1-ilo)metylo]benzoesowego z wodorosiarczynem i sposób jego wytwarzaniazynem i sposób jego wytwarzania

Also Published As

Publication number Publication date
EP0970073B1 (en) 2004-10-27
IN187999B (zh) 2002-08-03
AP1128A (en) 2002-12-06
JP4537499B2 (ja) 2010-09-01
EP0970073A4 (en) 2001-01-24
CO4950550A1 (es) 2000-09-01
JP2001510466A (ja) 2001-07-31
CZ285299A3 (cs) 2000-02-16
AP9901620A0 (en) 1999-09-30
RO119719B1 (ro) 2005-02-28
IN192743B (zh) 2004-05-15
AR011125A1 (es) 2000-08-02
SK285036B6 (sk) 2006-05-04
BG103650A (en) 2000-06-30
NO993913D0 (no) 1999-08-13
TR199901936T2 (xx) 2000-04-21
MY118704A (en) 2005-01-31
NO993913L (no) 1999-08-13
MA24470A1 (fr) 1998-10-01
PL335075A1 (en) 2000-04-10
SI0970073T1 (en) 2005-02-28
EP0970073A1 (en) 2000-01-12
OA11146A (en) 2003-04-16
IL131309A0 (en) 2001-01-28
CA2281708A1 (en) 1998-08-20
BR9808664A (pt) 2000-07-11
CN1247539A (zh) 2000-03-15
HU228781B1 (en) 2013-05-28
NZ337180A (en) 2000-11-24
ID23181A (id) 2000-03-23
PL192838B1 (pl) 2006-12-29
NO317194B1 (no) 2004-09-13
CA2281708C (en) 2007-08-14
EA199900740A1 (ru) 2000-02-28
SK108799A3 (en) 2000-05-16
DE69827240T2 (de) 2005-10-13
BG63804B1 (bg) 2003-01-31
IL131309A (en) 2002-09-12
ES2231963T3 (es) 2005-05-16
EA001659B1 (ru) 2001-06-25
ZA981207B (en) 1998-11-12
SA98190082B1 (ar) 2006-08-20
KR100573638B1 (ko) 2006-04-26
CY2555B1 (en) 2008-07-02
HUP0001994A2 (hu) 2001-06-28
AU730383B2 (en) 2001-03-08
WO1998035963A1 (en) 1998-08-20
PE59299A1 (es) 1999-09-09
ATE280765T1 (de) 2004-11-15
CZ296349B6 (cs) 2006-02-15
UA54487C2 (uk) 2003-03-17
US6172237B1 (en) 2001-01-09
DE69827240D1 (de) 2004-12-02
PT970073E (pt) 2005-02-28
KR20000071007A (ko) 2000-11-25
CN1085208C (zh) 2002-05-22
HUP0001994A3 (en) 2001-07-30
TW399050B (en) 2000-07-21
AU6150898A (en) 1998-09-08
EG23935A (en) 2008-01-14

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