PT970073E - Processo para a preparacao de eprosartan - Google Patents

Processo para a preparacao de eprosartan

Info

Publication number
PT970073E
PT970073E PT98906229T PT98906229T PT970073E PT 970073 E PT970073 E PT 970073E PT 98906229 T PT98906229 T PT 98906229T PT 98906229 T PT98906229 T PT 98906229T PT 970073 E PT970073 E PT 970073E
Authority
PT
Portugal
Prior art keywords
eprosartan
preparation
Prior art date
Application number
PT98906229T
Other languages
English (en)
Inventor
Li Liu
Flisak Joseph Robert
Clifford S Labaw
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of PT970073E publication Critical patent/PT970073E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
PT98906229T 1997-02-14 1998-02-13 Processo para a preparacao de eprosartan PT970073E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3819597P 1997-02-14 1997-02-14

Publications (1)

Publication Number Publication Date
PT970073E true PT970073E (pt) 2005-02-28

Family

ID=21898583

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98906229T PT970073E (pt) 1997-02-14 1998-02-13 Processo para a preparacao de eprosartan

Country Status (41)

Country Link
US (1) US6172237B1 (pt)
EP (1) EP0970073B1 (pt)
JP (1) JP4537499B2 (pt)
KR (1) KR100573638B1 (pt)
CN (1) CN1085208C (pt)
AP (1) AP1128A (pt)
AR (1) AR011125A1 (pt)
AT (1) ATE280765T1 (pt)
AU (1) AU730383B2 (pt)
BG (1) BG63804B1 (pt)
BR (1) BR9808664A (pt)
CA (1) CA2281708C (pt)
CO (1) CO4950550A1 (pt)
CY (1) CY2555B1 (pt)
CZ (1) CZ296349B6 (pt)
DE (1) DE69827240T2 (pt)
DK (1) DK0970073T3 (pt)
EA (1) EA001659B1 (pt)
EG (1) EG23935A (pt)
ES (1) ES2231963T3 (pt)
HU (1) HU228781B1 (pt)
ID (1) ID23181A (pt)
IL (1) IL131309A (pt)
IN (2) IN187999B (pt)
MA (1) MA24470A1 (pt)
MY (1) MY118704A (pt)
NO (1) NO317194B1 (pt)
NZ (1) NZ337180A (pt)
OA (1) OA11146A (pt)
PE (1) PE59299A1 (pt)
PL (1) PL192838B1 (pt)
PT (1) PT970073E (pt)
RO (1) RO119719B1 (pt)
SA (1) SA98190082B1 (pt)
SI (1) SI0970073T1 (pt)
SK (1) SK285036B6 (pt)
TR (1) TR199901936T2 (pt)
TW (1) TW399050B (pt)
UA (1) UA54487C2 (pt)
WO (1) WO1998035963A1 (pt)
ZA (1) ZA981207B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2097408A4 (en) * 2006-12-27 2010-08-25 Hetero Drugs Ltd IMPROVED PROCESS FOR THE PREPARATION OF EPROSARTAN
EP2295430A3 (en) * 2007-07-25 2011-08-03 Hetero Drugs Limited Crystalline solid of eprosartan acetate
WO2009013760A2 (en) * 2007-07-25 2009-01-29 Hetero Drugs Limited Eprosartan mesylate crystalline particles and a process for preparing pure eprosartan
WO2009084028A2 (en) * 2007-12-03 2009-07-09 Neuland Laboratories Ltd Improved process for manufacturing anhydrous (e)-3-[2-butyl-1- {(4-carboxyphenyl) methyl}-1h-imidazole-5-yl]-(thiophen-2- ylmethyl)prop-2-enoic acid methane sulfonate
CN101215284B (zh) * 2007-12-31 2010-10-13 浙江华海药业股份有限公司 一种改进的依普罗沙坦的制备方法
EP2257540A2 (en) * 2008-03-31 2010-12-08 Hetero Research Foundation Improved process for eprosartan intermediate
WO2010023688A2 (en) * 2008-08-25 2010-03-04 Matrix Laboratories Limited An improved process for the preparation of eprosartan
WO2011004384A2 (en) 2009-06-05 2011-01-13 Glochem Industries Limited Process for the preparation of eprosartan
WO2011051975A1 (en) 2009-10-30 2011-05-05 Matrix Laboratories Ltd An improved process for the preparation of pure eprosartanand its pharmaceutical acceptable salts

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5185351A (en) 1989-06-14 1993-02-09 Smithkline Beecham Corporation Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
NZ239161A (en) * 1990-07-31 1994-01-26 Smithkline Beecham Corp Substituted [1h-imidazol-5-yl] alkanoic acid derivatives; medicaments,
JP3214856B2 (ja) * 1990-12-14 2001-10-02 スミスクライン・ビーチャム・コーポレイション イミダゾリル−アルケン酸
US5395847A (en) * 1993-12-02 1995-03-07 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
HU221905B1 (hu) * 1994-05-20 2003-02-28 Smithkline Beecham Corporation Imidazolszármazék hidrogén-szulfit addíciós vegyülete

Also Published As

Publication number Publication date
AR011125A1 (es) 2000-08-02
US6172237B1 (en) 2001-01-09
SA98190082B1 (ar) 2006-08-20
ATE280765T1 (de) 2004-11-15
JP2001510466A (ja) 2001-07-31
NO317194B1 (no) 2004-09-13
KR20000071007A (ko) 2000-11-25
SI0970073T1 (en) 2005-02-28
RO119719B1 (ro) 2005-02-28
PL192838B1 (pl) 2006-12-29
AU6150898A (en) 1998-09-08
BG103650A (en) 2000-06-30
EA001659B1 (ru) 2001-06-25
CN1247539A (zh) 2000-03-15
HUP0001994A3 (en) 2001-07-30
EP0970073A4 (en) 2001-01-24
DE69827240T2 (de) 2005-10-13
PL335075A1 (en) 2000-04-10
OA11146A (en) 2003-04-16
AU730383B2 (en) 2001-03-08
JP4537499B2 (ja) 2010-09-01
CA2281708A1 (en) 1998-08-20
SK108799A3 (en) 2000-05-16
BR9808664A (pt) 2000-07-11
TW399050B (en) 2000-07-21
AP9901620A0 (en) 1999-09-30
IN187999B (pt) 2002-08-03
BG63804B1 (bg) 2003-01-31
NO993913L (no) 1999-08-13
EP0970073A1 (en) 2000-01-12
CN1085208C (zh) 2002-05-22
ZA981207B (en) 1998-11-12
IL131309A0 (en) 2001-01-28
CZ296349B6 (cs) 2006-02-15
NO993913D0 (no) 1999-08-13
TR199901936T2 (xx) 2000-04-21
PE59299A1 (es) 1999-09-09
IL131309A (en) 2002-09-12
SK285036B6 (sk) 2006-05-04
NZ337180A (en) 2000-11-24
DE69827240D1 (de) 2004-12-02
MY118704A (en) 2005-01-31
CZ285299A3 (cs) 2000-02-16
EA199900740A1 (ru) 2000-02-28
EG23935A (en) 2008-01-14
IN192743B (pt) 2004-05-15
CO4950550A1 (es) 2000-09-01
ES2231963T3 (es) 2005-05-16
MA24470A1 (fr) 1998-10-01
KR100573638B1 (ko) 2006-04-26
EP0970073B1 (en) 2004-10-27
ID23181A (id) 2000-03-23
HUP0001994A2 (hu) 2001-06-28
HU228781B1 (en) 2013-05-28
CA2281708C (en) 2007-08-14
WO1998035963A1 (en) 1998-08-20
CY2555B1 (en) 2008-07-02
DK0970073T3 (da) 2005-02-21
UA54487C2 (uk) 2003-03-17
AP1128A (en) 2002-12-06

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