DK0969102T3 - Primere, kits og sæt af restriktionsfragmenter anvendt ved selektiv restriktionsfragmentamplifikation - Google Patents

Primere, kits og sæt af restriktionsfragmenter anvendt ved selektiv restriktionsfragmentamplifikation

Info

Publication number
DK0969102T3
DK0969102T3 DK99115309T DK99115309T DK0969102T3 DK 0969102 T3 DK0969102 T3 DK 0969102T3 DK 99115309 T DK99115309 T DK 99115309T DK 99115309 T DK99115309 T DK 99115309T DK 0969102 T3 DK0969102 T3 DK 0969102T3
Authority
DK
Denmark
Prior art keywords
restriction
kits
primers
sets
fragments used
Prior art date
Application number
DK99115309T
Other languages
English (en)
Inventor
Marc Zabeau
Pieter Vos
Original Assignee
Keygene Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8208616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0969102(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Keygene Nv filed Critical Keygene Nv
Application granted granted Critical
Publication of DK0969102T3 publication Critical patent/DK0969102T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
  • Dental Preparations (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Power Conversion In General (AREA)
  • Auxiliary Devices For Music (AREA)
  • Reverberation, Karaoke And Other Acoustics (AREA)
DK99115309T 1991-09-24 1992-09-24 Primere, kits og sæt af restriktionsfragmenter anvendt ved selektiv restriktionsfragmentamplifikation DK0969102T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91402542 1991-09-24

Publications (1)

Publication Number Publication Date
DK0969102T3 true DK0969102T3 (da) 2008-05-13

Family

ID=8208616

Family Applications (2)

Application Number Title Priority Date Filing Date
DK92402629T DK0534858T4 (da) 1991-09-24 1992-09-24 Selektiv restriktionsfragmentamplifikation: en general fremgangsmåde til DNA-fingeraftryk-dannelse
DK99115309T DK0969102T3 (da) 1991-09-24 1992-09-24 Primere, kits og sæt af restriktionsfragmenter anvendt ved selektiv restriktionsfragmentamplifikation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK92402629T DK0534858T4 (da) 1991-09-24 1992-09-24 Selektiv restriktionsfragmentamplifikation: en general fremgangsmåde til DNA-fingeraftryk-dannelse

Country Status (20)

Country Link
US (1) US6045994A (da)
EP (2) EP0534858B2 (da)
JP (3) JP3236295B2 (da)
KR (1) KR100321510B1 (da)
AT (2) ATE191510T1 (da)
AU (1) AU672760B2 (da)
CA (1) CA2119557C (da)
CZ (2) CZ291877B6 (da)
DE (2) DE69230873T3 (da)
DK (2) DK0534858T4 (da)
ES (2) ES2147550T5 (da)
FI (2) FI113184B (da)
GR (1) GR3033895T3 (da)
HU (1) HU223760B1 (da)
IL (1) IL103267A (da)
NO (1) NO318016B1 (da)
PT (2) PT534858E (da)
RU (1) RU2182176C2 (da)
WO (1) WO1993006239A1 (da)
ZA (1) ZA927323B (da)

Families Citing this family (282)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6074818A (en) * 1990-08-24 2000-06-13 The University Of Tennessee Research Corporation Fingerprinting of nucleic acids, products and methods
US20100267023A1 (en) * 1992-09-24 2010-10-21 Keygene N.V. Selective restriction fragment amplification: fingerprinting
US7026115B1 (en) * 1991-09-24 2006-04-11 Keygene N.V. Selective restriction fragment amplification: fingerprinting
ZA929319B (en) * 1991-12-11 1993-05-24 Igen Inc Method for exponential amplification of nucleic acid by a single unpaired primer.
EP1382386A3 (en) * 1992-02-19 2004-12-01 The Public Health Research Institute Of The City Of New York, Inc. Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
GB9301776D0 (en) * 1993-01-29 1993-03-17 Univ Alberta Method for detecting genomic variation
US5470723A (en) * 1993-05-05 1995-11-28 Becton, Dickinson And Company Detection of mycobacteria by multiplex nucleic acid amplification
US5422252A (en) * 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
US5650274A (en) * 1993-06-25 1997-07-22 Hitachi, Ltd. DNA analyzing method
GB2283568B (en) * 1993-10-13 1997-12-24 Mini Agriculture & Fisheries Identification of fruit juice components
RU2111254C1 (ru) * 1994-07-11 1998-05-20 Институт молекулярной биологии им.В.А.Энгельгардта РАН СПОСОБ ДЕТЕКЦИИ ДИФФЕРЕНЦИАЛЬНО ЭКСПРЕССИРУЮЩИХСЯ МАТРИЧНЫХ РНК И КЛОНИРОВАНИЯ СООТВЕТСТВУЮЩИХ ИМ ФРАГМЕНТОВ кДНК
US5710000A (en) 1994-09-16 1998-01-20 Affymetrix, Inc. Capturing sequences adjacent to Type-IIs restriction sites for genomic library mapping
GB2295011A (en) * 1994-11-10 1996-05-15 Unilever Plc Selection of DNA markers using adaptor molecules
GB2295228A (en) * 1994-11-10 1996-05-22 Unilever Plc Selective amplification of DNA having a plurality of sites for a specific endonuclease
WO1996017082A2 (en) * 1994-11-28 1996-06-06 E.I. Du Pont De Nemours And Company Compound microsatellite primers for the detection of genetic polymorphisms
EP0718409A3 (en) * 1994-12-22 1999-02-03 Hitachi, Ltd. DNA preparation method
EP0721987A1 (en) * 1995-01-16 1996-07-17 Keygene N.V. Amplification of simple sequence repeats
US6031153A (en) * 1995-01-23 2000-02-29 Novartis Ag Method for protecting plants
US5565340A (en) * 1995-01-27 1996-10-15 Clontech Laboratories, Inc. Method for suppressing DNA fragment amplification during PCR
DE69621507T2 (de) * 1995-03-28 2003-01-09 Japan Science & Tech Corp Verfahren zur molekularen Indexierung von Genen unter Verwendung von Restriktionsenzymen
US6395887B1 (en) 1995-08-01 2002-05-28 Yale University Analysis of gene expression by display of 3'-end fragments of CDNAS
US5712126A (en) * 1995-08-01 1998-01-27 Yale University Analysis of gene expression by display of 3-end restriction fragments of CDNA
IL122973A0 (en) * 1995-08-07 1998-08-16 Keygene Nv Nucleic acid and its use in conferring resistance against wilt inducing fungi
US5871697A (en) * 1995-10-24 1999-02-16 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US5972693A (en) * 1995-10-24 1999-10-26 Curagen Corporation Apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US6418382B2 (en) 1995-10-24 2002-07-09 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US6218119B1 (en) 1996-01-16 2001-04-17 Keygene, N. V. Amplification of simple sequence repeats
WO1997029211A1 (en) * 1996-02-09 1997-08-14 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services RESTRICTION DISPLAY (RD-PCR) OF DIFFERENTIALLY EXPRESSED mRNAs
US6091004A (en) * 1996-06-21 2000-07-18 Novartis Finance Corporation Gene encoding a protein involved in the signal transduction cascade leading to systemic acquired resistance in plants
PT937155E (pt) 1996-08-09 2005-03-31 Keygene Nv Resistencia contra nematoides e/ou afidios
EP0823481A1 (en) 1996-08-09 1998-02-11 Keygene N.V. Resistance against nematodes
WO1998006736A1 (en) 1996-08-14 1998-02-19 Life Technologies, Inc. Stable compositions for nucleic acid amplification and sequencing
AU4174397A (en) 1996-08-30 1998-03-19 Life Technologies, Inc. Methods for identification and isolation of specific nucleotide sequences in cdna and genomic dna
US20040142327A1 (en) * 1996-11-22 2004-07-22 Jhy-Jhu Lin Methods for identifying and isolating DNA polymorphisms or genetic markers
US5986082A (en) * 1996-12-13 1999-11-16 Novartis Ag Altered forms of the NIM1 gene conferring disease resistance in plants
US5861295A (en) 1997-01-02 1999-01-19 Life Technologies, Inc. Nucleic acid-free thermostable enzymes and methods of production thereof
WO1998030721A1 (en) * 1997-01-10 1998-07-16 Pioneer Hi-Bred International, Inc. Hybridization-based genetic amplification and analysis
US6306588B1 (en) 1997-02-07 2001-10-23 Invitrogen Corporation Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof
ES2563643T3 (es) 1997-04-01 2016-03-15 Illumina Cambridge Limited Método de secuenciación de ácido nucleico
US6090556A (en) * 1997-04-07 2000-07-18 Japan Science & Technology Corporation Method for quantitatively determining the expression of a gene
DE69841241D1 (de) 1997-04-22 2009-11-26 Life Technologies Corp Verfahren zur herstellung von aslv reverser transkriptase zusammengestellt aus mehreren untereinheiten
AU727748B2 (en) 1997-08-07 2000-12-21 Curagen Corporation Detection and confirmation of nucleic acid sequences by use of oligonucleotides comprising a subsequence hybridizing exactly to a known terminal sequence and a subsequence hybridizing to an undentified sequence
US6673577B1 (en) * 1997-08-07 2004-01-06 Curagen Corporation Detection and confirmation of nucleic acid sequences by use of poisoning oligonucleotides
US6833242B2 (en) * 1997-09-23 2004-12-21 California Institute Of Technology Methods for detecting and sorting polynucleotides based on size
WO1999023256A1 (en) * 1997-10-30 1999-05-14 Cold Spring Harbor Laboratory Probe arrays and methods of using probe arrays for distinguishing dna
JP2002501760A (ja) * 1998-02-02 2002-01-22 アマーシャム・ファルマシア・バイオテック・アクチボラグ 核酸解析方法
AU3747099A (en) 1998-04-16 1999-11-01 Case Western Reserve University Method for finding genetic markers of somaclonal variation
US6324479B1 (en) 1998-05-08 2001-11-27 Rosetta Impharmatics, Inc. Methods of determining protein activity levels using gene expression profiles
US6218122B1 (en) 1998-06-19 2001-04-17 Rosetta Inpharmatics, Inc. Methods of monitoring disease states and therapies using gene expression profiles
DE69813203T2 (de) * 1998-07-21 2004-02-12 Keygene N.V. Verbesserte Primer zur AFLP Amplifizierung
DE69816286T2 (de) 1998-07-29 2004-05-27 Keygene N.V. Verfahren zur Erkennung von Nukleinsäuremethylierungen durch AFLP
US6306593B1 (en) * 1998-09-17 2001-10-23 Union Camp Corporation Selective AFLP primers for reduction of complexity of maker genotyping and DNA markers for loblolly pine identified using the AFLP primers
US6146830A (en) 1998-09-23 2000-11-14 Rosetta Inpharmatics, Inc. Method for determining the presence of a number of primary targets of a drug
US6703228B1 (en) 1998-09-25 2004-03-09 Massachusetts Institute Of Technology Methods and products related to genotyping and DNA analysis
JP3855492B2 (ja) * 1998-10-08 2006-12-13 株式会社日立製作所 混合核酸断片分析法
WO2000021358A1 (en) 1998-10-14 2000-04-20 Agriculture And Agri-Food Canada Hybrid alfalfa (medicago sativa)
AU2144000A (en) 1998-10-27 2000-05-15 Affymetrix, Inc. Complexity management and analysis of genomic dna
US6468476B1 (en) 1998-10-27 2002-10-22 Rosetta Inpharmatics, Inc. Methods for using-co-regulated genesets to enhance detection and classification of gene expression patterns
US6950752B1 (en) 1998-10-27 2005-09-27 Rosetta Inpharmatics Llc Methods for removing artifact from biological profiles
US6203987B1 (en) 1998-10-27 2001-03-20 Rosetta Inpharmatics, Inc. Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns
WO2000028081A2 (en) * 1998-11-09 2000-05-18 Methexis N.V. Restricted amplicon analysis
US6801859B1 (en) 1998-12-23 2004-10-05 Rosetta Inpharmatics Llc Methods of characterizing drug activities using consensus profiles
US6370478B1 (en) 1998-12-28 2002-04-09 Rosetta Inpharmatics, Inc. Methods for drug interaction prediction using biological response profiles
US6222093B1 (en) 1998-12-28 2001-04-24 Rosetta Inpharmatics, Inc. Methods for determining therapeutic index from gene expression profiles
US6605432B1 (en) * 1999-02-05 2003-08-12 Curators Of The University Of Missouri High-throughput methods for detecting DNA methylation
US6630333B1 (en) 1999-03-23 2003-10-07 Invitrogen Corporation Substantially pure reverse transriptases and methods of production thereof
ATE386819T1 (de) * 1999-04-09 2008-03-15 Keygene Nv Verfahren zur analyse von aflp reaktionsmischungen unter verwendung von primer verlängerungstechniken
US6994969B1 (en) 1999-04-30 2006-02-07 Methexis Genomics, N.V. Diagnostic sequencing by a combination of specific cleavage and mass spectrometry
JP3969091B2 (ja) 1999-06-23 2007-08-29 株式会社日立製作所 遠心分離機及びこれを用いる試料調製装置
US20020119448A1 (en) * 1999-06-23 2002-08-29 Joseph A. Sorge Methods of enriching for and identifying polymorphisms
US6420117B1 (en) 1999-09-14 2002-07-16 The University Of Georgia Research Foundation, Inc. Miniature inverted repeat transposable elements and methods of use
US6221600B1 (en) 1999-10-08 2001-04-24 Board Of Regents, The University Of Texas System Combinatorial oligonucleotide PCR: a method for rapid, global expression analysis
US6958225B2 (en) 1999-10-27 2005-10-25 Affymetrix, Inc. Complexity management of genomic DNA
AUPQ439699A0 (en) * 1999-12-01 1999-12-23 University Of Sydney, The Detection of nucleic acid fragments
AU3246601A (en) 1999-12-29 2001-07-16 Keygene N.V. Method for generating oligonucleotides, in particular for the detection of amplified restriction fragments obtained using AFLP
AU2001254670A1 (en) * 2000-03-02 2001-09-12 Akzo Nobel N.V. Detection of hepatitis b virus rna
NZ521626A (en) 2000-03-29 2005-09-30 Cambia Methods for genotyping by hybridization analysis
US7217516B2 (en) * 2000-05-15 2007-05-15 Keygene N.V. Methods and kits comprising AFLP primers, and ramp primers with a part complementary to a compound microsatellite repeat and an anchor part complementary to nucleotides adjacent to the repeat
US7078208B2 (en) 2000-05-26 2006-07-18 Invitrogen Corporation Thermostable reverse transcriptases and uses thereof
JP2004511211A (ja) 2000-05-26 2004-04-15 インヴィトロジェン　コーポレーション 耐熱性逆転写酵素およびその使用
AU2001271720A1 (en) 2000-07-05 2002-01-14 Rosetta Inpharmatics, Inc. Methods and compositions for determining gene function
US6984522B2 (en) 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
AR031640A1 (es) * 2000-12-08 2003-09-24 Applied Research Systems Amplificacion isotermica de acidos nucleicos en un soporte solido
US20030143554A1 (en) * 2001-03-31 2003-07-31 Berres Mark E. Method of genotyping by determination of allele copy number
WO2002081729A2 (en) 2001-04-06 2002-10-17 California Institute Of Technology Nucleic acid amplification utilizing microfluidic devices
EP1386002A4 (en) 2001-04-16 2006-11-08 Applera Corp METHOD AND COMPOSITIONS FOR NUCLEOTIDE ANALYSIS
WO2002086169A1 (en) * 2001-04-23 2002-10-31 Dana-Farber Cancer Institute, Inc. Methods for rapid screening of polymorphisms, mutations and methylation
US20030044785A1 (en) * 2001-05-01 2003-03-06 American Type Culture Collection Method for identifying and genotyping microorganisms
CA2449782C (en) 2001-06-07 2011-01-04 Pioneer Hi-Bred International, Inc. Qtl controlling sclerotinia stem rot resistance in soybean
GB0114853D0 (en) * 2001-06-18 2001-08-08 Medical Res Council Happier Mapping
EP1421175B1 (en) 2001-06-28 2008-11-19 Mountain View Pharmaceuticals, Inc. Polymer stabilized proteinases
WO2003010516A1 (en) * 2001-07-23 2003-02-06 Curagen Corporation Method for identifying a nucleic acid sequence
US6872529B2 (en) * 2001-07-25 2005-03-29 Affymetrix, Inc. Complexity management of genomic DNA
CA2467577A1 (en) * 2001-11-19 2003-05-30 Parallele Bioscience, Inc. Multiplex pcr
US20110151438A9 (en) 2001-11-19 2011-06-23 Affymetrix, Inc. Methods of Analysis of Methylation
AU2002358110A1 (en) * 2001-12-10 2003-07-09 Novartis Ag Methods of treating psychosis and schizophrenia based on a polymorphism in the ctf gene
US7418351B2 (en) 2002-01-31 2008-08-26 Rosetta Inpharmatics Llc Methods for analysis of measurement errors in measured signals
EP1483720A1 (en) 2002-02-01 2004-12-08 Rosetta Inpharmactis LLC. Computer systems and methods for identifying genes and determining pathways associated with traits
AU2003208480A1 (en) * 2002-03-05 2003-09-16 Lynx Therapeutics INC. Methods for detecting genome-wide sequence variations associated with a phenotype
US20040110166A1 (en) * 2002-03-07 2004-06-10 Macevicz Stephen C. Genome-wide scanning of genetic polymorphisms
WO2003085379A2 (en) 2002-04-01 2003-10-16 Fluidigm Corporation Microfluidic particle-analysis systems
JP2005522224A (ja) 2002-04-12 2005-07-28 キュアレイターズ オブ ザ ユニバーシティー オブ ミズーリ Ｄｎａの高メチル化と遺伝子サイレンシングの両方をスクリーニングするためのｅｃｉｓｔマイクロアレイと、そのｅｃｉｓｔマイクロアレイを利用して遺伝子の発現、ｄｎａのメチル化、ヒストンのアセチル化を評価するための統合システム
US7115370B2 (en) * 2002-06-05 2006-10-03 Capital Genomix, Inc. Combinatorial oligonucleotide PCR
US9388459B2 (en) 2002-06-17 2016-07-12 Affymetrix, Inc. Methods for genotyping
US20040072217A1 (en) * 2002-06-17 2004-04-15 Affymetrix, Inc. Methods of analysis of linkage disequilibrium
ES2380929T3 (es) 2002-08-22 2012-05-21 Novartis Ag Diagnóstico de rechazo crónico
AU2003274973A1 (en) 2002-09-13 2004-04-30 Invitrogen Corporation Thermostable reverse transcriptases and uses thereof
EP2213615A3 (en) 2002-09-25 2012-02-29 California Institute of Technology Microfluidic Large Scale Integration
EP1546412B1 (en) 2002-10-02 2014-05-21 California Institute Of Technology Microfluidic nucleic acid analysis
US7459273B2 (en) * 2002-10-04 2008-12-02 Affymetrix, Inc. Methods for genotyping selected polymorphism
US20040219565A1 (en) 2002-10-21 2004-11-04 Sakari Kauppinen Oligonucleotides useful for detecting and analyzing nucleic acids of interest
WO2004063323A2 (en) * 2003-01-10 2004-07-29 Keygene N.V. Aflp-based method for integrating physical and genetic maps
US7996155B2 (en) 2003-01-22 2011-08-09 Microsoft Corporation ANOVA method for data analysis
ATE437945T1 (de) * 2003-01-29 2009-08-15 454 Corp Verfahren zur amplifikation und sequenzierung von nukleinsäuren
CA2555962C (en) * 2003-02-26 2015-10-06 Callida Genomics, Inc. Random array dna analysis by hybridization
DE602004029560D1 (de) * 2003-03-07 2010-11-25 Rubicon Genomics Inc Amplifikation und analyse von gesamtgenom- und gesamttranskriptom- bibliotheken, die durch ein dns-polymerisierungsverfahren produziert wurden
US8206913B1 (en) 2003-03-07 2012-06-26 Rubicon Genomics, Inc. Amplification and analysis of whole genome and whole transcriptome libraries generated by a DNA polymerization process
WO2005018534A2 (en) 2003-05-16 2005-03-03 Rosetta Inpharmatics, Llc Methods and compositions for rna interference
US8694263B2 (en) 2003-05-23 2014-04-08 Cold Spring Harbor Laboratory Method of identifying virtual representations of nucleotide sequences
US20040259100A1 (en) * 2003-06-20 2004-12-23 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
JP2007525963A (ja) 2003-06-20 2007-09-13 イルミナ インコーポレイテッド 全ゲノム増幅および遺伝型決定のための方法および組成物
US20050181394A1 (en) * 2003-06-20 2005-08-18 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US20060246457A1 (en) * 2003-07-02 2006-11-02 Keygene N.V. Splice site aflp
US20050032102A1 (en) * 2003-07-22 2005-02-10 Affymetrix, Inc. Mapping genomic rearrangements
US8114978B2 (en) 2003-08-05 2012-02-14 Affymetrix, Inc. Methods for genotyping selected polymorphism
US7269517B2 (en) 2003-09-05 2007-09-11 Rosetta Inpharmatics Llc Computer systems and methods for analyzing experiment design
US9394565B2 (en) 2003-09-05 2016-07-19 Agena Bioscience, Inc. Allele-specific sequence variation analysis
EP2469439A2 (en) 2003-09-29 2012-06-27 Pathwork Diagnostics, Inc. Systems and methods for detecting biological features
EP1725682B1 (en) 2004-03-08 2015-09-09 Rubicon Genomics, Inc. Methods and compositions for generating and amplifying dna libraries for sensitive detection and analysis of dna methylation
EP1574585A1 (en) * 2004-03-12 2005-09-14 Plant Research International B.V. Method for selective amplification of DNA fragments for genetic fingerprinting
EP1727911B1 (en) 2004-03-26 2013-01-23 Sequenom, Inc. Base specific cleavage of methylation-specific amplification products in combination with mass analysis
US8192937B2 (en) * 2004-04-07 2012-06-05 Exiqon A/S Methods for quantification of microRNAs and small interfering RNAs
US8135595B2 (en) 2004-05-14 2012-03-13 H. Lee Moffitt Cancer Center And Research Institute, Inc. Computer systems and methods for providing health care
WO2005118877A2 (en) 2004-06-02 2005-12-15 Vicus Bioscience, Llc Producing, cataloging and classifying sequence tags
EP1623996A1 (en) * 2004-08-06 2006-02-08 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Improved method of selecting a desired protein from a library
FR2876378B1 (fr) * 2004-10-08 2007-01-05 Univ Joseph Fourier Etablissem Amorces universelles et leur utilisation pour la detection et l'identification de vegetaux dans des melanges complexes
US7335760B2 (en) 2004-12-22 2008-02-26 Ceres, Inc. Nucleic acid sequences encoding zinc finger proteins
US9505846B2 (en) 2005-01-28 2016-11-29 Life Technologies Corporation Multi-component inhibitors of nucleic acid polymerases
AU2006222151B2 (en) 2005-03-03 2011-05-19 Rijk Zwaan Zaadteelt En Zaadhandel B.V. Reverse progeny mapping
KR101317730B1 (ko) 2005-03-03 2013-10-15 리즈크 즈완 자드틸트 엔 자드한델 비.브이. 근접 후향 육종 방법
US20060223066A1 (en) 2005-03-29 2006-10-05 Applera Corporation Methods for normalizing and for identifying small nucleic acids
US7452671B2 (en) 2005-04-29 2008-11-18 Affymetrix, Inc. Methods for genotyping with selective adaptor ligation
CA2612145A1 (en) * 2005-05-10 2006-11-16 Eric A. Johnson Methods of mapping polymorphisms and polymorphism microarrays
EP3492602A1 (en) 2005-06-15 2019-06-05 Complete Genomics, Inc. Single molecule arrays for genetic and chemical analysis
CN101641449B (zh) 2005-06-23 2014-01-29 科因股份有限公司 用于多态性的高通量鉴定和检测的策略
WO2006137734A1 (en) * 2005-06-23 2006-12-28 Keygene N.V. Improved strategies for sequencing complex genomes using high throughput sequencing technologies
GB0514935D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Methods for sequencing a polynucleotide template
GB0514910D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Method for sequencing a polynucleotide template
EP1924705A1 (en) 2005-08-02 2008-05-28 Rubicon Genomics, Inc. Isolation of cpg islands by thermal segregation and enzymatic selection-amplification method
US20070031857A1 (en) 2005-08-02 2007-02-08 Rubicon Genomics, Inc. Compositions and methods for processing and amplification of DNA, including using multiple enzymes in a single reaction
US7622121B2 (en) 2005-09-21 2009-11-24 New York University Heat shock proteins from Mycobacterium leprae and uses thereof
ATE453728T1 (de) 2005-09-29 2010-01-15 Keygene Nv Screening mutagenisierter populationen mit hohem durchsatz
US10316364B2 (en) 2005-09-29 2019-06-11 Keygene N.V. Method for identifying the source of an amplicon
US7960104B2 (en) 2005-10-07 2011-06-14 Callida Genomics, Inc. Self-assembled single molecule arrays and uses thereof
WO2007044245A2 (en) 2005-10-07 2007-04-19 Callida Genomics, Inc. Self-assembled single molecule arrays and uses thereof
GB0522310D0 (en) 2005-11-01 2005-12-07 Solexa Ltd Methods of preparing libraries of template polynucleotides
EP2299267A3 (en) 2005-11-16 2011-05-04 Novartis AG Biomarkers for anti-NogoA antibody treatment in spinal cord injury
GB0524069D0 (en) * 2005-11-25 2006-01-04 Solexa Ltd Preparation of templates for solid phase amplification
US8137936B2 (en) * 2005-11-29 2012-03-20 Macevicz Stephen C Selected amplification of polynucleotides
US11306351B2 (en) 2005-12-21 2022-04-19 Affymetrix, Inc. Methods for genotyping
CN101374963B (zh) 2005-12-22 2014-06-04 凯津公司 用于基于aflp的高通量多态性检测的方法
US8222482B2 (en) 2006-01-26 2012-07-17 Ceres, Inc. Modulating plant oil levels
CA2641851A1 (en) 2006-02-08 2007-08-16 Eric Hans Vermaas Method for sequencing a polynucleotide template
SG170028A1 (en) * 2006-02-24 2011-04-29 Callida Genomics Inc High throughput genome sequencing on dna arrays
CN101432439B (zh) * 2006-02-24 2013-07-24 考利达基因组股份有限公司 Dna阵列上的高通量基因组测序
ES2301342B1 (es) * 2006-03-14 2009-05-01 Oryzon Genomics, S.A. "metodo de analisis de acidos nucleicos".
US20080009420A1 (en) * 2006-03-17 2008-01-10 Schroth Gary P Isothermal methods for creating clonal single molecule arrays
ES2545264T3 (es) * 2006-04-04 2015-09-09 Keygene N.V. Detección de alto rendimiento de marcadores moleculares basada en fragmentos de restricción
US20130191941A1 (en) 2006-07-05 2013-07-25 Shing Kwok Modulating light response pathways in plants, increasing light-related tolerances in plants, and increasing biomass in plants
EP2275576B1 (en) 2006-07-12 2013-09-04 Keygene N.V. High throughput physical mapping using AFLP
US9328378B2 (en) * 2006-07-31 2016-05-03 Illumina Cambridge Limited Method of library preparation avoiding the formation of adaptor dimers
US7754429B2 (en) 2006-10-06 2010-07-13 Illumina Cambridge Limited Method for pair-wise sequencing a plurity of target polynucleotides
CA2665016A1 (en) 2006-10-18 2008-04-24 Seminis Vegetable Seeds, Inc. Carrots having increased lycopene content
US7910302B2 (en) * 2006-10-27 2011-03-22 Complete Genomics, Inc. Efficient arrays of amplified polynucleotides
US20090105961A1 (en) * 2006-11-09 2009-04-23 Complete Genomics, Inc. Methods of nucleic acid identification in large-scale sequencing
US20090111706A1 (en) 2006-11-09 2009-04-30 Complete Genomics, Inc. Selection of dna adaptor orientation by amplification
EP2121983A2 (en) 2007-02-02 2009-11-25 Illumina Cambridge Limited Methods for indexing samples and sequencing multiple nucleotide templates
EP2130927A4 (en) * 2007-03-07 2010-08-04 Univ Tokyo METHOD FOR AMPLIFYING A DNA FRAGMENT
US20080293589A1 (en) * 2007-05-24 2008-11-27 Affymetrix, Inc. Multiplex locus specific amplification
CL2008001682A1 (es) 2007-06-08 2008-12-12 Monsanto Technology Llc Metodos para el mejoramiento de plantas mediante el uso de informacion directa de secuencias de acidos nucleicos.
SI2167667T1 (sl) 2007-07-09 2016-03-31 Bayer Cropscience Nv Rastlina Brassica, ki vsebuje mutirane alele maščobne acil-ACP tioesteraze
US9388457B2 (en) 2007-09-14 2016-07-12 Affymetrix, Inc. Locus specific amplification using array probes
WO2009052214A2 (en) * 2007-10-15 2009-04-23 Complete Genomics, Inc. Sequence analysis using decorated nucleic acids
US7897344B2 (en) * 2007-11-06 2011-03-01 Complete Genomics, Inc. Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs
US7901890B2 (en) * 2007-11-05 2011-03-08 Complete Genomics, Inc. Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation
US20090263872A1 (en) * 2008-01-23 2009-10-22 Complete Genomics Inc. Methods and compositions for preventing bias in amplification and sequencing reactions
US8415099B2 (en) 2007-11-05 2013-04-09 Complete Genomics, Inc. Efficient base determination in sequencing reactions
US8518640B2 (en) * 2007-10-29 2013-08-27 Complete Genomics, Inc. Nucleic acid sequencing and process
US8298768B2 (en) 2007-11-29 2012-10-30 Complete Genomics, Inc. Efficient shotgun sequencing methods
MX2010004863A (es) 2007-11-02 2010-07-28 Ceres Inc Materiales y metodos para usarse en el procesamiento de biomasa.
NL2000992C2 (nl) 2007-11-09 2009-05-12 Nunhems Bv Nieuwe komkommerplanten met compacte groeiwijze.
CN101970667B (zh) 2007-11-28 2014-04-09 拜尔作物科学公司 包含突变indehiscent等位基因的芸苔属植物
US8592150B2 (en) 2007-12-05 2013-11-26 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
WO2009097368A2 (en) 2008-01-28 2009-08-06 Complete Genomics, Inc. Methods and compositions for efficient base calling in sequencing reactions
CA3224206A1 (en) 2008-02-15 2009-08-20 Ceres, Inc. Drought and heat tolerance in plants
US9074244B2 (en) 2008-03-11 2015-07-07 Affymetrix, Inc. Array-based translocation and rearrangement assays
WO2009132028A1 (en) * 2008-04-21 2009-10-29 Complete Genomics, Inc. Array structures for nucleic acid detection
US9121074B2 (en) 2008-05-26 2015-09-01 Bayer Cropscience N.V. Gossypium hirsutum plants with increased fiber strength comprising a fiber strength allele spanning the GLUC1.1A gene from Gossypium barbadense
JP5770086B2 (ja) 2008-07-17 2015-08-26 バイエル・クロップサイエンス・エヌ・ヴェーＢａｙｅｒ Ｃｒｏｐｓｃｉｅｎｃｅ Ｎ．Ｖ． 突然変異株ＩＮＤＥＨＩＳＣＥＮＴアレルを有するアブラナ属（Ｂｒａｓｓｉｃａ）植物
EP2172565A1 (en) * 2008-09-24 2010-04-07 Cyano Biotech GmbH Method of identifying and/or differentiating cyanophyta
US20110287492A1 (en) * 2008-12-04 2011-11-24 Keygene N.V. Method for the reduction of repetitive sequences in adapter-ligated restriction fragments
EP2379751B1 (en) 2009-01-13 2013-03-20 Keygene N.V. Novel genome sequencing strategies
WO2010105275A2 (en) 2009-03-13 2010-09-16 Cornell University Method to assess human allograft status from microrna expression levels
US8071865B2 (en) 2009-04-15 2011-12-06 Monsanto Technology Llc Plants and seeds of corn variety CV589782
US8362332B2 (en) 2009-04-15 2013-01-29 Monsanto Technology Llc Plants and seeds of corn variety CV165560
US8071864B2 (en) 2009-04-15 2011-12-06 Monsanto Technology Llc Plants and seeds of corn variety CV897903
EP2248914A1 (en) * 2009-05-05 2010-11-10 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. The use of class IIB restriction endonucleases in 2nd generation sequencing applications
US9524369B2 (en) 2009-06-15 2016-12-20 Complete Genomics, Inc. Processing and analysis of complex nucleic acid sequence data
US8779241B2 (en) 2009-07-07 2014-07-15 Enza Zaden Beheer B.V. Cucumber vein yellowing virus (CVYV) resistant cucumber plants (Cucumis sativus L.)
EA202091701A1 (ru) 2009-07-20 2021-01-29 Серес, Инк. Увеличение биомассы трансгенных растений
US20110059453A1 (en) * 2009-08-23 2011-03-10 Affymetrix, Inc. Poly(A) Tail Length Measurement by PCR
SI2669387T1 (sl) 2009-08-25 2017-01-31 Illumina, Inc. Metode za izbiro in pomnoževanje polinukleotidov
WO2011071382A1 (en) * 2009-12-10 2011-06-16 Keygene N.V. Polymorfphic whole genome profiling
EP2333104A1 (en) 2009-12-11 2011-06-15 Lexogen GmbH RNA analytics method
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
CA2783548A1 (en) 2009-12-17 2011-06-23 Keygene N.V. Restriction enzyme based whole genome sequencing
EP2354243A1 (en) 2010-02-03 2011-08-10 Lexogen GmbH Complexity reduction method
US9746479B2 (en) 2010-03-09 2017-08-29 Cornell University Methods and compositions to predict and detect acute rejection
NL2004412C2 (en) 2010-03-16 2011-09-20 Nickerson Zwaan B V Male sterile leek plants.
US9313961B2 (en) 2010-04-20 2016-04-19 Seminis Vegetable Seeds, Inc. White-stem trait containing plants
WO2011140329A1 (en) 2010-05-06 2011-11-10 Ceres, Inc. Transgenic plants having increased biomass
EP3425062B1 (en) 2010-06-09 2023-08-02 Keygene N.V. Combinatorial sequence barcodes for high throughput screening
BR112013010278B1 (pt) 2010-10-27 2020-12-29 Ceres, Inc método para produzir uma planta, método para modular a composição de biomassa em uma planta, ácido nucleico isolado e método para alterar a composição de biomassa em uma planta
US8766054B2 (en) 2010-12-08 2014-07-01 Hm.Clause Phytophthora resistance in sweet peppers
WO2012084742A1 (en) 2010-12-24 2012-06-28 Bayer Cropscience Nv Brassica plant comprising a mutant alcatraz allele
WO2012096579A2 (en) 2011-01-14 2012-07-19 Keygene N.V. Paired end random sequence based genotyping
TWI465572B (zh) * 2011-05-19 2014-12-21 Univ Chang Gung Method, composition and system of amplification and detection of target microbial DNA
CA2840929C (en) 2011-07-08 2020-03-24 Keygene N.V. Sequence based genotyping based on oligonucleotide ligation assays
CA2848304A1 (en) 2011-09-09 2013-03-14 The Board Of Trustees Of The Leland Stanford Junior University Methods for sequencing a polynucleotide
BR122020026845B1 (pt) 2011-11-02 2021-04-13 Ceres, Inc Método de aumento do rendimento de planta em solo contendo níveis elevados de al3+, método de aumento da tolerância de uma planta
WO2013086499A2 (en) 2011-12-09 2013-06-13 Ceres, Inc. Transgenic plants having altered biomass composition
CN108611398A (zh) 2012-01-13 2018-10-02 Data生物有限公司 通过新一代测序进行基因分型
LT3363901T (lt) 2012-02-17 2021-04-12 Fred Hutchinson Cancer Research Center Kompozicijos ir būdai, skirti tiksliam mutacijų nustatymui
WO2013130512A2 (en) 2012-02-27 2013-09-06 The University Of North Carolina At Chapel Hill Methods and uses for molecular tags
AR091671A1 (es) 2012-07-06 2015-02-18 Bayer Cropscience Nv Plantas de brassica con semillas con una composicion de aceites modificada
CA2878286C (en) 2012-07-06 2023-06-13 Bayer Cropscience Nv Brassica rod1 gene sequences and uses thereof
CA2878287A1 (en) 2012-07-06 2014-01-09 Bayer Cropscience Nv Soybean rod1 gene sequences and uses thereof
EP2728013A1 (en) * 2012-10-31 2014-05-07 Universitätsspital Basel Method for the simultaneous amplification of a plurality of different nucleic acid target sequences
US9758828B2 (en) 2013-01-31 2017-09-12 Cornell University Methods to detect, treat and prevent acute cellular rejection in kidney allografts
AR095880A1 (es) 2013-04-19 2015-11-18 Bayer Cropscience Nv Plantas de brassica híbridas y métodos para producirlas
RU2549453C2 (ru) * 2013-04-26 2015-04-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" НАБОР СИНТЕТИЧЕСКИХ ОЛИГОНУКЛЕОТИДОВ ДЛЯ ВЫЯВЛЕНИЯ ВИДОВОЙ ПРИНАДЛЕЖНОСТИ ВЕРЕСКА ОБЫКНОВЕННОГО (Calluna vulgaris (L.) Hull.)
CN103233072B (zh) * 2013-05-06 2014-07-02 中国海洋大学 一种高通量全基因组dna甲基化检测技术
RU2535060C1 (ru) * 2013-05-30 2014-12-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" НАБОР СИНТЕТИЧЕСКИХ ОЛИГОНУКЛЕОТИДОВ ДЛЯ ВЫЯВЛЕНИЯ ВИДОВОЙ ПРИНАДЛЕЖНОСТИ АРАЛИИ ВЫСОКОЙ (Aralia elata (Miq.) Seem.)
RU2535064C1 (ru) * 2013-05-30 2014-12-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" НАБОР СИНТЕТИЧЕСКИХ ОЛИГОНУКЛЕОТИДОВ ДЛЯ ВЫЯВЛЕНИЯ ВИДОВОЙ ПРИНАДЛЕЖНОСТИ СВОБОДНОЯГОДНИКА КОЛЮЧЕГО, ЭЛЕУТЕРОКОККА (Eleutherococcus senticocus (Rupr. et Maxim.) Maxim.)
RU2535063C1 (ru) * 2013-05-30 2014-12-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" НАБОР СИНТЕТИЧЕCКИХ ОЛИГОНУКЛЕОТИДОВ ДЛЯ ВЫЯВЛЕНИЯ ВИДОВОЙ ПРИНАДЛЕЖНОСТИ СУШЕНИЦЫ БОЛОТНОЙ (Filaginella uliginosa (L.) Opiz)
US9982301B2 (en) 2014-01-07 2018-05-29 Cornell University Urine mRNA profile and acute dysfunction of kidney allograft
US9663770B2 (en) 2014-01-22 2017-05-30 Life Technologies Corporation Reverse transcriptases for use in high temperature nucleic acid synthesis
US20140245471A1 (en) 2014-05-02 2014-08-28 Nunhems B.V. Carrot plants with a high anthocyanin level
US9107356B2 (en) 2014-05-02 2015-08-18 Nunhems B.V. Hybrid carrot variety NUN 85931
PL3169785T3 (pl) 2014-07-15 2022-05-23 Forage Genetics International, Llc Sposób zwiększania plonu w warunkach stresu abiotycznego
RU2573937C1 (ru) * 2014-10-20 2016-01-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" НАБОР СИНТЕТИЧЕСКИХ ОЛИГОНУКЛЕОТИДОВ ДЛЯ ВЫЯВЛЕНИЯ ВИДОВОЙ ПРИНАДЛЕЖНОСТИ ВОЛОДУШКИ МНОГОЖИЛЬЧАТОЙ (Bupleurum multinerve DC.)
JP6797794B2 (ja) 2014-10-30 2020-12-09 ヌンヘムス、ベスローテン、フェンノートシャップＮｕｎｈｅｍｓ Ｂ．Ｖ． レタスヒゲナガアブラムシ（Ｎａｓｏｎｏｖｉａ ｒｉｂｉｓｎｉｇｒｉ）バイオタイプ１に対する抵抗性を含んでなるレタス植物
WO2016174119A1 (en) 2015-04-28 2016-11-03 Bayer Cropscience Nv Brassica plants with modified seed oil composition
EP3344774A1 (en) 2015-09-04 2018-07-11 Keygene N.V. Diplospory gene
US10226015B2 (en) 2015-11-10 2019-03-12 Pop Vriend Research B.V. Peronospora resistance in Spinacia sp
US11277983B2 (en) 2015-11-10 2022-03-22 Pop Vriend Seeds Bv Peronospora resistance in spinacia sp
WO2018091438A1 (en) 2016-11-17 2018-05-24 Nunhems B.V. Multibranching artichoke plant
US11584958B2 (en) 2017-03-31 2023-02-21 Grail, Llc Library preparation and use thereof for sequencing based error correction and/or variant identification
WO2019068647A1 (en) 2017-10-04 2019-04-11 Hild Samen Gmbh TOTAL RESISTANCE TO THE MILDIOU IN THE BASIL
MX2020007466A (es) 2018-01-12 2020-11-12 Basf Se Gen subyacente al qtl de la cantidad de espiguillas por espiga en trigo en el cromosoma 7a.
JP7467343B2 (ja) 2018-01-26 2024-04-15 ヌンヘムス、ベスローテン、フェンノートシャップ 少なくともＰｅｒｏｎｏｓｐｏｒａ ｆａｒｉｎｏｓａのレース８、９、１１、１３および１６に耐性のホウレンソウ植物
EP3887538A1 (en) 2018-11-28 2021-10-06 Keygene N.V. Targeted enrichment by endonuclease protection
EP3893631A1 (en) 2018-12-13 2021-10-20 Nunhems B.V. Solanaceous plant capable of stenospermocarpic fruit formation
AU2020225760A1 (en) 2019-02-21 2021-08-19 Keygene N.V. Genotyping of polyploids
AU2020285344A1 (en) 2019-05-29 2021-11-11 Keygene N.V. Gene for parthenogenesis
CA3134097A1 (en) 2019-06-13 2020-12-17 Wim VRIEZEN Tomato plant producing fruit having improved ripening characteristics
JP2023504022A (ja) 2019-11-26 2023-02-01 ヌンヘムス、ベスローテン、フェンノートシャップ タマネギにおける低減ピルベートレベル形質に関する分子マーカー
EP4073245A1 (en) 2019-12-12 2022-10-19 Keygene N.V. Semi-solid state nucleic acid manipulation
WO2021123062A1 (en) 2019-12-20 2021-06-24 Keygene N.V. Ngs library preparation using covalently closed nucleic acid molecule ends
IL297475A (en) 2020-04-23 2022-12-01 Nunhems Bv Tomato plants with improved resistance to Tobamo virus
CA3178083A1 (en) 2020-05-13 2021-11-18 Wim VRIEZEN Tomato plants having suppressed meiotic recombination
KR20230023711A (ko) 2020-06-10 2023-02-17 넌헴스 비.브이. 개선된 총채벌레 저항성을 갖는 캅시쿰 아누움 식물
WO2022074058A1 (en) 2020-10-06 2022-04-14 Keygene N.V. Targeted sequence addition
EP4228398A1 (en) 2020-10-13 2023-08-23 Keygene N.V. Modified promoter of a parthenogenesis gene
WO2022112316A1 (en) 2020-11-24 2022-06-02 Keygene N.V. Targeted enrichment using nanopore selective sequencing
WO2022140762A1 (en) 2020-12-21 2022-06-30 BASF Agricultural Solutions Seed US LLC Brassica napus plants comprising an improved fertility restorer
WO2022144003A1 (zh) * 2020-12-31 2022-07-07 东科智生基因科技（北京）有限公司 一种用于高通量靶向测序的多重pcr文库构建方法
WO2022265965A1 (en) 2021-06-14 2022-12-22 10X Genomics, Inc. Reverse transcriptase variants for improved performance
WO2023004429A1 (en) 2021-07-23 2023-01-26 BASF Agricultural Solutions Seed US LLC Blackleg resistant plants and methods for the identification of blackleg resistant plants
US12004476B2 (en) 2022-01-26 2024-06-11 Monsanto Technology Llc. Cotton variety 20R750B3XF
WO2024121354A1 (en) 2022-12-08 2024-06-13 Keygene N.V. Duplex sequencing with covalently closed dna ends

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4321365A (en) * 1977-10-19 1982-03-23 Research Corporation Oligonucleotides useful as adaptors in DNA cloning, adapted DNA molecules, and methods of preparing adaptors and adapted molecules
US5093245A (en) * 1988-01-26 1992-03-03 Applied Biosystems Labeling by simultaneous ligation and restriction
WO1990008821A1 (en) * 1989-01-31 1990-08-09 University Of Miami Microdissection and amplification of chromosomal dna
WO1990012115A1 (en) * 1989-03-21 1990-10-18 Collaborative Research, Inc. A dna diagnostic test using an exonuclease activity
EP0495911A1 (en) * 1989-10-16 1992-07-29 Genelabs Technologies, Inc. Non-specific dna amplification
WO1991014003A2 (en) * 1990-03-09 1991-09-19 Ig Laboratories, Inc. Characterization and analysis of polymorphic vntr loci
US5126239A (en) * 1990-03-14 1992-06-30 E. I. Du Pont De Nemours And Company Process for detecting polymorphisms on the basis of nucleotide differences
WO1992007095A1 (en) * 1990-10-15 1992-04-30 Stratagene Arbitrarily primed polymerase chain reaction method for fingerprinting genomes
AU1426392A (en) * 1991-01-22 1992-08-27 Board Of Regents, The University Of Texas System 5' and 3' polymerase chain reaction walking from known dna sequences

Also Published As

Publication number Publication date
EP0534858B1 (en) 2000-04-05
EP0534858A1 (en) 1993-03-31
JP2001061486A (ja) 2001-03-13
ATE382094T1 (de) 2008-01-15
EP0969102B1 (en) 2007-12-26
FI941360A (fi) 1994-05-24
RU2182176C2 (ru) 2002-05-10
DE69230873T3 (de) 2006-04-06
JPH06510668A (ja) 1994-12-01
KR100321510B1 (ko) 2005-01-10
PT969102E (pt) 2008-03-25
AU2662992A (en) 1993-04-27
EP0969102A3 (en) 2000-02-23
DK0534858T4 (da) 2005-08-08
NO941064D0 (no) 1994-03-23
EP0534858B2 (en) 2005-04-27
NO318016B1 (no) 2005-01-24
RU94033149A (ru) 1996-07-27
JP4385072B2 (ja) 2009-12-16
US6045994A (en) 2000-04-04
FI115402B (fi) 2005-04-29
CA2119557C (en) 2004-02-24
ES2147550T3 (es) 2000-09-16
HU9400809D0 (en) 1994-06-28
JP3236295B2 (ja) 2001-12-10
HU223760B1 (hu) 2005-01-28
ES2299229T3 (es) 2008-05-16
WO1993006239A1 (en) 1993-04-01
JP2008131947A (ja) 2008-06-12
AU672760B2 (en) 1996-10-17
ZA927323B (en) 1993-08-30
PT534858E (pt) 2000-09-29
NO941064L (no) 1994-05-20
DK0534858T3 (da) 2000-09-11
DE69230873T2 (de) 2000-11-09
DE69233719T2 (de) 2009-01-02
ES2147550T5 (es) 2005-11-01
DE69233719D1 (de) 2008-02-07
HUT68504A (en) 1995-06-28
CA2119557A1 (en) 1993-04-01
FI20031526A (fi) 2003-10-17
DE69230873D1 (de) 2000-05-11
ATE191510T1 (de) 2000-04-15
EP0969102A2 (en) 2000-01-05
FI113184B (fi) 2004-03-15
CZ291877B6 (cs) 2003-06-18
IL103267A0 (en) 1993-02-21
JP4088403B2 (ja) 2008-05-21
GR3033895T3 (en) 2000-11-30
CZ66994A3 (en) 1994-12-15
CZ298187B6 (cs) 2007-07-18
FI941360A0 (fi) 1994-03-24
IL103267A (en) 2004-07-25

Similar Documents

Publication Publication Date Title
DK0969102T3 (da) Primere, kits og sæt af restriktionsfragmenter anvendt ved selektiv restriktionsfragmentamplifikation
PT84207B (pt) Processo para a expressao de genes em plantas, fragmentos de adn, plasmideos e microrganismos transformados
DE69331665T2 (de) Methode zur behandlung von nukleinsäureproben
DE69636080D1 (de) Eine in Kaskaden verlaufende Vervielfältigungsreaktion von Nukleinsäuren
DE69329636T2 (de) Verfahren zur Vervielfältigung von Nukleinsäuresequenzen
ATE397092T1 (de) Methode zur direkten sequenzierung von nukleinsäuren
ATE106948T1 (de) Verfahren zur amplifizierung von nukleinsäuren.
DK0592836T3 (da) DNA af integrationsstedet for humant adenoassocieret virus og dets anvendelse
DE59609841D1 (de) Verfahren zur Gattungs- und speziesspezifische Identifizierung von Legionellen
ES2063206T3 (es) Procedimiento para secuenciacion de acidos desoxirribonucleicos.
ATE230033T1 (de) Verwendung von primern für universelle fingerprint-analysen
DK0647718T3 (da) Genetiske fingeraftryk af gær
ATE108834T1 (de) Spezifische nukleinsäurefragmente des menschlichen villingens, ihre anwendung für diagnostische zwecke.
IT1188647B (it) Metodo per conservare pellami,pelli e pellicce grezzi
NO892990D0 (no) Midler og metode for oekning av nukleinsyrehybridisering.
KR920014935A (ko) 사슬 치환에 의한 증폭방법
ATE45561T1 (de) Verfahren und anlage zur indirekten schlammtrocknung insbesondere von abwaesserschlaemmen.