DE69636080D1 - Eine in Kaskaden verlaufende Vervielfältigungsreaktion von Nukleinsäuren - Google Patents

Eine in Kaskaden verlaufende Vervielfältigungsreaktion von Nukleinsäuren

Info

Publication number
DE69636080D1
DE69636080D1 DE69636080T DE69636080T DE69636080D1 DE 69636080 D1 DE69636080 D1 DE 69636080D1 DE 69636080 T DE69636080 T DE 69636080T DE 69636080 T DE69636080 T DE 69636080T DE 69636080 D1 DE69636080 D1 DE 69636080D1
Authority
DE
Germany
Prior art keywords
oligonucleotide
nucleic acids
amplification reaction
circular
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69636080T
Other languages
English (en)
Other versions
DE69636080T2 (de
Inventor
Erland Koch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olink AB
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69636080D1 publication Critical patent/DE69636080D1/de
Publication of DE69636080T2 publication Critical patent/DE69636080T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
DE69636080T 1995-12-05 1996-12-05 Eine in Kaskaden verlaufende Vervielfältigungsreaktion von Nukleinsäuren Expired - Lifetime DE69636080T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK137995 1995-12-05
DK137995 1995-12-05

Publications (2)

Publication Number Publication Date
DE69636080D1 true DE69636080D1 (de) 2006-06-01
DE69636080T2 DE69636080T2 (de) 2006-11-30

Family

ID=8104224

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69636080T Expired - Lifetime DE69636080T2 (de) 1995-12-05 1996-12-05 Eine in Kaskaden verlaufende Vervielfältigungsreaktion von Nukleinsäuren
DE69627698T Expired - Lifetime DE69627698T2 (de) 1995-12-05 1996-12-05 Eine in kaskaden verlaufende vervielfältigungsreaktion von nukleinsäuren

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69627698T Expired - Lifetime DE69627698T2 (de) 1995-12-05 1996-12-05 Eine in kaskaden verlaufende vervielfältigungsreaktion von nukleinsäuren

Country Status (9)

Country Link
US (1) US6610481B2 (de)
EP (2) EP0868530B1 (de)
AT (2) ATE324464T1 (de)
AU (1) AU704750B2 (de)
CA (1) CA2239287C (de)
DE (2) DE69636080T2 (de)
DK (2) DK1300466T3 (de)
ES (1) ES2262902T3 (de)
WO (1) WO1997020948A1 (de)

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WO2003002761A1 (en) * 2001-06-29 2003-01-09 Novozymes A/S Method of multimerization and site-directed mutagenesis
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US8394944B2 (en) * 2002-09-20 2013-03-12 Siemens Healthcare Diagnostics Inc. Dual-purpose primers and probes for providing enhanced hybridization assays by disruption of secondary structure formation
WO2004048596A2 (en) 2002-11-21 2004-06-10 Epicentre Technologies Methods for using primers that encode one strand of a double-stranded promoter
US9487823B2 (en) 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
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US7989166B2 (en) 2005-04-12 2011-08-02 In Situ Rcp A/S Circle probes and their use in the identification of biomolecules
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DK1907583T4 (da) 2005-06-15 2020-01-27 Complete Genomics Inc Enkeltmolekyle-arrays til genetisk og kemisk analyse
EP1762627A1 (de) 2005-09-09 2007-03-14 Qiagen GmbH Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
EP2377929A1 (de) 2005-10-06 2011-10-19 Lucigen Corporation Wärmestabile virale Polymerasen und Verwendungsverfahren
WO2007133831A2 (en) 2006-02-24 2007-11-22 Callida Genomics, Inc. High throughput genome sequencing on dna arrays
US7960104B2 (en) * 2005-10-07 2011-06-14 Callida Genomics, Inc. Self-assembled single molecule arrays and uses thereof
US20070168197A1 (en) * 2006-01-18 2007-07-19 Nokia Corporation Audio coding
SG170028A1 (en) * 2006-02-24 2011-04-29 Callida Genomics Inc High throughput genome sequencing on dna arrays
GB0621361D0 (en) * 2006-10-26 2006-12-06 Fermentas Uab Use of DNA polymerases
US7910302B2 (en) 2006-10-27 2011-03-22 Complete Genomics, Inc. Efficient arrays of amplified polynucleotides
US20090111705A1 (en) 2006-11-09 2009-04-30 Complete Genomics, Inc. Selection of dna adaptor orientation by hybrid capture
US20090105961A1 (en) * 2006-11-09 2009-04-23 Complete Genomics, Inc. Methods of nucleic acid identification in large-scale sequencing
RU2414510C2 (ru) * 2007-06-14 2011-03-20 Институт биохимии и генетики Уфимского научного центра РАН Способ амплификации специфичных фрагментов нуклеиновых кислот с помощью рекуррентной цепной реакции
US20090263872A1 (en) * 2008-01-23 2009-10-22 Complete Genomics Inc. Methods and compositions for preventing bias in amplification and sequencing reactions
US7901890B2 (en) * 2007-11-05 2011-03-08 Complete Genomics, Inc. Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation
US8298768B2 (en) * 2007-11-29 2012-10-30 Complete Genomics, Inc. Efficient shotgun sequencing methods
US8617811B2 (en) * 2008-01-28 2013-12-31 Complete Genomics, Inc. Methods and compositions for efficient base calling in sequencing reactions
US8415099B2 (en) 2007-11-05 2013-04-09 Complete Genomics, Inc. Efficient base determination in sequencing reactions
US7897344B2 (en) * 2007-11-06 2011-03-01 Complete Genomics, Inc. Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs
US8518640B2 (en) * 2007-10-29 2013-08-27 Complete Genomics, Inc. Nucleic acid sequencing and process
US8592150B2 (en) 2007-12-05 2013-11-26 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
US20090270273A1 (en) * 2008-04-21 2009-10-29 Complete Genomics, Inc. Array structures for nucleic acid detection
US9524369B2 (en) 2009-06-15 2016-12-20 Complete Genomics, Inc. Processing and analysis of complex nucleic acid sequence data
US9556473B2 (en) 2011-02-15 2017-01-31 Leica Biosystems Newcastle Ltd Methods for identifying nucleic acid sequences
WO2012110899A2 (en) 2011-02-15 2012-08-23 Bernitz Mats Nilsson Method for localizedin situdetection of mrna
EP2718465B1 (de) 2011-06-09 2022-04-13 Illumina, Inc. Verfahren zur vorbereitung eines analyt-arrays
AU2012328662B2 (en) 2011-10-28 2015-12-17 Illumina, Inc. Microarray fabrication system and method
EP2920324B1 (de) 2012-11-14 2017-12-27 Olink Bioscience AB Lokalisiertes rca-basiertes verstärkungsverfahren
US20160369321A1 (en) 2012-11-14 2016-12-22 Olink Ab RCA Reporter Probes and Their Use in Detecting Nucleic Acid Molecules
GB201320145D0 (en) 2013-11-14 2014-01-01 Olink Ab Localised RCA-based amplification method using a padlock-probe
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EP3237641B1 (de) * 2014-12-24 2020-04-08 Abbott Laboratories Nachweisverfahren, -zusammensetzung und -kit basierend auf signalverstärker kaskade dna reaktionen mit einer verlängerung der zielnukleinsäure
GB201614023D0 (en) 2016-08-16 2016-09-28 Olink Bioscience Ab Double-stranded circle probes
KR20230166141A (ko) 2016-12-09 2023-12-06 얼티뷰, 인크. 표지된 핵산 조영제를 사용한 다중 이미지형성을 위한 개선된 방법
EP3601339A4 (de) 2017-03-31 2020-11-04 Ultivue, Inc. Dna-antigenaustausch und amplifikation

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US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
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JP3085409B2 (ja) * 1991-03-29 2000-09-11 東洋紡績株式会社 標的核酸配列の検出方法およびそのための試薬キット
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Also Published As

Publication number Publication date
DK0868530T3 (da) 2003-07-21
ATE324464T1 (de) 2006-05-15
ATE238434T1 (de) 2003-05-15
DE69636080T2 (de) 2006-11-30
EP0868530B1 (de) 2003-04-23
EP1300466B1 (de) 2006-04-26
EP1300466A2 (de) 2003-04-09
ES2262902T3 (es) 2006-12-01
AU704750B2 (en) 1999-05-06
EP0868530A1 (de) 1998-10-07
CA2239287A1 (en) 1997-06-12
US20020031764A1 (en) 2002-03-14
US6610481B2 (en) 2003-08-26
AU7691796A (en) 1997-06-27
DE69627698D1 (de) 2003-05-28
EP1300466A3 (de) 2004-01-02
DK1300466T3 (da) 2006-08-28
CA2239287C (en) 2008-02-26
DE69627698T2 (de) 2004-01-15
WO1997020948A1 (en) 1997-06-12

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Legal Events

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8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: OLINK AB, UPPSALA, SE