PT969102E - Iniciadores, grupos e conjuntos de fragmentos de restrição usados na amplificação selectiva de fragmentos de restrição - Google Patents

Iniciadores, grupos e conjuntos de fragmentos de restrição usados na amplificação selectiva de fragmentos de restrição Download PDF

Info

Publication number
PT969102E
PT969102E PT99115309T PT99115309T PT969102E PT 969102 E PT969102 E PT 969102E PT 99115309 T PT99115309 T PT 99115309T PT 99115309 T PT99115309 T PT 99115309T PT 969102 E PT969102 E PT 969102E
Authority
PT
Portugal
Prior art keywords
restriction
kits
primers
sets
fragments used
Prior art date
Application number
PT99115309T
Other languages
English (en)
Inventor
Marc Zabeau
Pieter Vos
Original Assignee
Keygene Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8208616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT969102(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Keygene Nv filed Critical Keygene Nv
Publication of PT969102E publication Critical patent/PT969102E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Dental Preparations (AREA)
  • Auxiliary Devices For Music (AREA)
  • Power Conversion In General (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Reverberation, Karaoke And Other Acoustics (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT99115309T 1991-09-24 1992-09-24 Iniciadores, grupos e conjuntos de fragmentos de restrição usados na amplificação selectiva de fragmentos de restrição PT969102E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91402542 1991-09-24

Publications (1)

Publication Number Publication Date
PT969102E true PT969102E (pt) 2008-03-25

Family

ID=8208616

Family Applications (2)

Application Number Title Priority Date Filing Date
PT99115309T PT969102E (pt) 1991-09-24 1992-09-24 Iniciadores, grupos e conjuntos de fragmentos de restrição usados na amplificação selectiva de fragmentos de restrição
PT92402629T PT534858E (pt) 1991-09-24 1992-09-24 Amplificacao selectiva de fragmentos de restricao um metodo geral para a obtencao de "impressoes digitais" do adn

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT92402629T PT534858E (pt) 1991-09-24 1992-09-24 Amplificacao selectiva de fragmentos de restricao um metodo geral para a obtencao de "impressoes digitais" do adn

Country Status (20)

Country Link
US (1) US6045994A (pt)
EP (2) EP0534858B2 (pt)
JP (3) JP3236295B2 (pt)
KR (1) KR100321510B1 (pt)
AT (2) ATE191510T1 (pt)
AU (1) AU672760B2 (pt)
CA (1) CA2119557C (pt)
CZ (2) CZ298187B6 (pt)
DE (2) DE69230873T3 (pt)
DK (2) DK0534858T4 (pt)
ES (2) ES2299229T3 (pt)
FI (2) FI113184B (pt)
GR (1) GR3033895T3 (pt)
HU (1) HU223760B1 (pt)
IL (1) IL103267A (pt)
NO (1) NO318016B1 (pt)
PT (2) PT969102E (pt)
RU (1) RU2182176C2 (pt)
WO (1) WO1993006239A1 (pt)
ZA (1) ZA927323B (pt)

Families Citing this family (284)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6074818A (en) * 1990-08-24 2000-06-13 The University Of Tennessee Research Corporation Fingerprinting of nucleic acids, products and methods
US20100267023A1 (en) * 1992-09-24 2010-10-21 Keygene N.V. Selective restriction fragment amplification: fingerprinting
US7026115B1 (en) * 1991-09-24 2006-04-11 Keygene N.V. Selective restriction fragment amplification: fingerprinting
ZA929319B (en) * 1991-12-11 1993-05-24 Igen Inc Method for exponential amplification of nucleic acid by a single unpaired primer.
CA2130562A1 (en) * 1992-02-19 1993-09-02 Alexander B. Chetverin Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids
GB9301776D0 (en) * 1993-01-29 1993-03-17 Univ Alberta Method for detecting genomic variation
US5470723A (en) * 1993-05-05 1995-11-28 Becton, Dickinson And Company Detection of mycobacteria by multiplex nucleic acid amplification
US5422252A (en) * 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
US5650274A (en) * 1993-06-25 1997-07-22 Hitachi, Ltd. DNA analyzing method
GB2283568B (en) * 1993-10-13 1997-12-24 Mini Agriculture & Fisheries Identification of fruit juice components
RU2111254C1 (ru) * 1994-07-11 1998-05-20 Институт молекулярной биологии им.В.А.Энгельгардта РАН СПОСОБ ДЕТЕКЦИИ ДИФФЕРЕНЦИАЛЬНО ЭКСПРЕССИРУЮЩИХСЯ МАТРИЧНЫХ РНК И КЛОНИРОВАНИЯ СООТВЕТСТВУЮЩИХ ИМ ФРАГМЕНТОВ кДНК
US5710000A (en) * 1994-09-16 1998-01-20 Affymetrix, Inc. Capturing sequences adjacent to Type-IIs restriction sites for genomic library mapping
GB2295228A (en) * 1994-11-10 1996-05-22 Unilever Plc Selective amplification of DNA having a plurality of sites for a specific endonuclease
GB2295011A (en) * 1994-11-10 1996-05-15 Unilever Plc Selection of DNA markers using adaptor molecules
EP0804618B1 (en) * 1994-11-28 1999-01-27 E.I. Du Pont De Nemours And Company Compound microsatellite primers for the detection of genetic polymorphisms
EP0718409A3 (en) * 1994-12-22 1999-02-03 Hitachi, Ltd. DNA preparation method
EP0721987A1 (en) * 1995-01-16 1996-07-17 Keygene N.V. Amplification of simple sequence repeats
US6031153A (en) * 1995-01-23 2000-02-29 Novartis Ag Method for protecting plants
US5565340A (en) * 1995-01-27 1996-10-15 Clontech Laboratories, Inc. Method for suppressing DNA fragment amplification during PCR
EP0735144B1 (en) * 1995-03-28 2002-06-05 Japan Science and Technology Corporation Method for molecular indexing of genes using restriction enzymes
US6395887B1 (en) 1995-08-01 2002-05-28 Yale University Analysis of gene expression by display of 3'-end fragments of CDNAS
US5712126A (en) * 1995-08-01 1998-01-27 Yale University Analysis of gene expression by display of 3-end restriction fragments of CDNA
JP2000507082A (ja) * 1995-08-07 2000-06-13 ケイヘーネ・エヌ・ブイ 萎凋を誘発する真菌に対する抵抗性
US6418382B2 (en) 1995-10-24 2002-07-09 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US5972693A (en) * 1995-10-24 1999-10-26 Curagen Corporation Apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US5871697A (en) 1995-10-24 1999-02-16 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US6218119B1 (en) 1996-01-16 2001-04-17 Keygene, N. V. Amplification of simple sequence repeats
AU2264197A (en) * 1996-02-09 1997-08-28 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Restriction display (rd-pcr) of differentially expressed mrnas
US6091004A (en) * 1996-06-21 2000-07-18 Novartis Finance Corporation Gene encoding a protein involved in the signal transduction cascade leading to systemic acquired resistance in plants
EP0823481A1 (en) 1996-08-09 1998-02-11 Keygene N.V. Resistance against nematodes
PT937155E (pt) 1996-08-09 2005-03-31 Keygene Nv Resistencia contra nematoides e/ou afidios
WO1998006736A1 (en) 1996-08-14 1998-02-19 Life Technologies, Inc. Stable compositions for nucleic acid amplification and sequencing
EP1007730A4 (en) * 1996-08-30 2004-04-28 Invitrogen Corp METHODS OF IDENTIFYING AND ISOLATING SPECIFIC NUCLEOTIDE SEQUENCES IN cDNA AND GENOMIC DNA
US20040142327A1 (en) * 1996-11-22 2004-07-22 Jhy-Jhu Lin Methods for identifying and isolating DNA polymorphisms or genetic markers
US5986082A (en) * 1996-12-13 1999-11-16 Novartis Ag Altered forms of the NIM1 gene conferring disease resistance in plants
US5861295A (en) 1997-01-02 1999-01-19 Life Technologies, Inc. Nucleic acid-free thermostable enzymes and methods of production thereof
US6100030A (en) * 1997-01-10 2000-08-08 Pioneer Hi-Bred International, Inc. Use of selective DNA fragment amplification products for hybridization-based genetic fingerprinting, marker assisted selection, and high-throughput screening
US6306588B1 (en) 1997-02-07 2001-10-23 Invitrogen Corporation Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof
JP2002503954A (ja) 1997-04-01 2002-02-05 グラクソ、グループ、リミテッド 核酸増幅法
US6090556A (en) * 1997-04-07 2000-07-18 Japan Science & Technology Corporation Method for quantitatively determining the expression of a gene
US6989259B2 (en) 1997-04-22 2006-01-24 Invitrogen Corporation Recombinant methods for making reverse transcriptases and mutants thereof
US6673577B1 (en) * 1997-08-07 2004-01-06 Curagen Corporation Detection and confirmation of nucleic acid sequences by use of poisoning oligonucleotides
US6190868B1 (en) 1997-08-07 2001-02-20 Curagen Corporation Method for identifying a nucleic acid sequence
US6833242B2 (en) * 1997-09-23 2004-12-21 California Institute Of Technology Methods for detecting and sorting polynucleotides based on size
JP2001521754A (ja) * 1997-10-30 2001-11-13 コールド スプリング ハーバー ラボラトリー Ｄｎａ識別のためのプローブアレイ及びプローブアレイの使用方法
US6280954B1 (en) * 1998-02-02 2001-08-28 Amersham Pharmacia Biotech Ab Arrayed primer extension technique for nucleic acid analysis
US6500616B1 (en) 1998-04-16 2002-12-31 Case Western Reserve University Methods of monitoring genomic integrity and detecting genomic destabilization of plant cells in tissue culture
US6324479B1 (en) 1998-05-08 2001-11-27 Rosetta Impharmatics, Inc. Methods of determining protein activity levels using gene expression profiles
US6218122B1 (en) 1998-06-19 2001-04-17 Rosetta Inpharmatics, Inc. Methods of monitoring disease states and therapies using gene expression profiles
EP0974672B1 (en) * 1998-07-21 2003-04-09 Keygene N.V. Improved primers for AFLP amplification
EP0976835B1 (en) * 1998-07-29 2003-07-09 Keygene N.V. Method for detecting nucleic acid methylation using AFLPTM
US6306593B1 (en) * 1998-09-17 2001-10-23 Union Camp Corporation Selective AFLP primers for reduction of complexity of maker genotyping and DNA markers for loblolly pine identified using the AFLP primers
US6146830A (en) * 1998-09-23 2000-11-14 Rosetta Inpharmatics, Inc. Method for determining the presence of a number of primary targets of a drug
US6703228B1 (en) 1998-09-25 2004-03-09 Massachusetts Institute Of Technology Methods and products related to genotyping and DNA analysis
JP3855492B2 (ja) * 1998-10-08 2006-12-13 株式会社日立製作所 混合核酸断片分析法
WO2000021358A1 (en) 1998-10-14 2000-04-20 Agriculture And Agri-Food Canada Hybrid alfalfa (medicago sativa)
AU2144000A (en) * 1998-10-27 2000-05-15 Affymetrix, Inc. Complexity management and analysis of genomic dna
US6468476B1 (en) 1998-10-27 2002-10-22 Rosetta Inpharmatics, Inc. Methods for using-co-regulated genesets to enhance detection and classification of gene expression patterns
US6203987B1 (en) 1998-10-27 2001-03-20 Rosetta Inpharmatics, Inc. Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns
US6950752B1 (en) 1998-10-27 2005-09-27 Rosetta Inpharmatics Llc Methods for removing artifact from biological profiles
DE69919566D1 (de) * 1998-11-09 2004-09-23 Methexis Genomics N V Analyse von "amplikons" erhalten durch restriktionsendonukleasen
US6801859B1 (en) 1998-12-23 2004-10-05 Rosetta Inpharmatics Llc Methods of characterizing drug activities using consensus profiles
US6370478B1 (en) 1998-12-28 2002-04-09 Rosetta Inpharmatics, Inc. Methods for drug interaction prediction using biological response profiles
US6222093B1 (en) 1998-12-28 2001-04-24 Rosetta Inpharmatics, Inc. Methods for determining therapeutic index from gene expression profiles
US6605432B1 (en) * 1999-02-05 2003-08-12 Curators Of The University Of Missouri High-throughput methods for detecting DNA methylation
US6630333B1 (en) 1999-03-23 2003-10-07 Invitrogen Corporation Substantially pure reverse transriptases and methods of production thereof
US7169552B1 (en) * 1999-04-09 2007-01-30 Keygene N.V. Detection of polymorphisms in AFLP fragments using primer extension techniques
US6994969B1 (en) 1999-04-30 2006-02-07 Methexis Genomics, N.V. Diagnostic sequencing by a combination of specific cleavage and mass spectrometry
US20020119448A1 (en) * 1999-06-23 2002-08-29 Joseph A. Sorge Methods of enriching for and identifying polymorphisms
US6808633B1 (en) 1999-06-23 2004-10-26 Hitachi, Ltd. Centrifugal separator and sample preparation device using the separator
US6420117B1 (en) 1999-09-14 2002-07-16 The University Of Georgia Research Foundation, Inc. Miniature inverted repeat transposable elements and methods of use
US6221600B1 (en) * 1999-10-08 2001-04-24 Board Of Regents, The University Of Texas System Combinatorial oligonucleotide PCR: a method for rapid, global expression analysis
US6958225B2 (en) 1999-10-27 2005-10-25 Affymetrix, Inc. Complexity management of genomic DNA
AUPQ439699A0 (en) * 1999-12-01 1999-12-23 University Of Sydney, The Detection of nucleic acid fragments
AU3246601A (en) * 1999-12-29 2001-07-16 Keygene N.V. Method for generating oligonucleotides, in particular for the detection of amplified restriction fragments obtained using AFLP
AU2001254670A1 (en) * 2000-03-02 2001-09-12 Akzo Nobel N.V. Detection of hepatitis b virus rna
AU6052001A (en) 2000-03-29 2001-10-08 Ct For The Applic Of Molecular Methods for genotyping by hybridization analysis
EP1282729A2 (en) * 2000-05-15 2003-02-12 Keygene N.V. Microsatellite-aflp
US7078208B2 (en) 2000-05-26 2006-07-18 Invitrogen Corporation Thermostable reverse transcriptases and uses thereof
AU2001271270A1 (en) 2000-05-26 2001-12-11 Invitrogen Corporation Thermostable reverse transcriptases and uses thereof
US20040209276A1 (en) 2002-09-13 2004-10-21 Smith Michael D. Thermostable reverse transcriptases and uses thereof
AU2001271720A1 (en) 2000-07-05 2002-01-14 Rosetta Inpharmatics, Inc. Methods and compositions for determining gene function
US6984522B2 (en) 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
AR031640A1 (es) * 2000-12-08 2003-09-24 Applied Research Systems Amplificacion isotermica de acidos nucleicos en un soporte solido
US20030143554A1 (en) * 2001-03-31 2003-07-31 Berres Mark E. Method of genotyping by determination of allele copy number
US6960437B2 (en) * 2001-04-06 2005-11-01 California Institute Of Technology Nucleic acid amplification utilizing microfluidic devices
WO2002083955A1 (en) * 2001-04-16 2002-10-24 Applera Corporation Methods and compositions for nucleotide analysis
WO2002086169A1 (en) * 2001-04-23 2002-10-31 Dana-Farber Cancer Institute, Inc. Methods for rapid screening of polymorphisms, mutations and methylation
US20030044785A1 (en) * 2001-05-01 2003-03-06 American Type Culture Collection Method for identifying and genotyping microorganisms
BR0209700A (pt) 2001-06-07 2004-10-13 Pioneer Hi Bred Int Resistência à produção de sclerotinia por controle de qtl em soja
GB0114853D0 (en) * 2001-06-18 2001-08-08 Medical Res Council Happier Mapping
WO2003002716A2 (en) 2001-06-28 2003-01-09 Mountain View Pharmaceuticals, Inc. Polymer stabilized proteinases
WO2003010516A1 (en) * 2001-07-23 2003-02-06 Curagen Corporation Method for identifying a nucleic acid sequence
US6872529B2 (en) * 2001-07-25 2005-03-29 Affymetrix, Inc. Complexity management of genomic DNA
US20110151438A9 (en) 2001-11-19 2011-06-23 Affymetrix, Inc. Methods of Analysis of Methylation
CA2467460A1 (en) 2001-11-19 2003-05-30 Parallele Bioscience, Inc. Multiplex oligonucleotide addition and target amplification
SI1458888T1 (sl) * 2001-12-10 2011-07-29 Novartis Ag Metode zdravljenja psihoze in shizofrenije na osnovi polimorfizmov gena cntf
US7418351B2 (en) 2002-01-31 2008-08-26 Rosetta Inpharmatics Llc Methods for analysis of measurement errors in measured signals
WO2003065282A1 (en) 2002-02-01 2003-08-07 Rosetta Inpharmatics Llc Computer systems and methods for identifying genes and determining pathways associated with traits
EP1483404A2 (en) * 2002-03-05 2004-12-08 Solexa Ltd. Methods for detecting genome-wide sequence variations associated with a phenotype
US20040110166A1 (en) * 2002-03-07 2004-06-10 Macevicz Stephen C. Genome-wide scanning of genetic polymorphisms
EP1499706A4 (en) 2002-04-01 2010-11-03 Fluidigm Corp MICROFLUIDIC PARTICLE ANALYSIS SYSTEMS
JP2005522224A (ja) 2002-04-12 2005-07-28 キュアレイターズ オブ ザ ユニバーシティー オブ ミズーリ Ｄｎａの高メチル化と遺伝子サイレンシングの両方をスクリーニングするためのｅｃｉｓｔマイクロアレイと、そのｅｃｉｓｔマイクロアレイを利用して遺伝子の発現、ｄｎａのメチル化、ヒストンのアセチル化を評価するための統合システム
US7115370B2 (en) * 2002-06-05 2006-10-03 Capital Genomix, Inc. Combinatorial oligonucleotide PCR
US20040072217A1 (en) * 2002-06-17 2004-04-15 Affymetrix, Inc. Methods of analysis of linkage disequilibrium
US9388459B2 (en) 2002-06-17 2016-07-12 Affymetrix, Inc. Methods for genotyping
ATE546547T1 (de) 2002-08-22 2012-03-15 Novartis Pharma Gmbh Diagnose der chronischen abstossung
JP2006501056A (ja) 2002-09-25 2006-01-12 カリフォルニア インスティテュート オブ テクノロジー ミクロ流体大規模集積
WO2004040001A2 (en) 2002-10-02 2004-05-13 California Institute Of Technology Microfluidic nucleic acid analysis
US7459273B2 (en) * 2002-10-04 2008-12-02 Affymetrix, Inc. Methods for genotyping selected polymorphism
US20040219565A1 (en) 2002-10-21 2004-11-04 Sakari Kauppinen Oligonucleotides useful for detecting and analyzing nucleic acids of interest
ES2394881T3 (es) * 2003-01-10 2013-02-06 Keygene N.V. Procedimiento basado en la AFLP para la integración de mapas físicos y genéticos
US7996155B2 (en) 2003-01-22 2011-08-09 Microsoft Corporation ANOVA method for data analysis
ES2396245T3 (es) * 2003-01-29 2013-02-20 454 Life Sciences Corporation Método de amplificación y secuenciamiento de ácidos nucleicos
AU2004214891B2 (en) * 2003-02-26 2010-01-07 Complete Genomics, Inc. Random array DNA analysis by hybridization
US8206913B1 (en) 2003-03-07 2012-06-26 Rubicon Genomics, Inc. Amplification and analysis of whole genome and whole transcriptome libraries generated by a DNA polymerization process
ATE484598T1 (de) * 2003-03-07 2010-10-15 Rubicon Genomics Inc Amplifikation und analyse von gesamtgenom- und gesamttranskriptom- bibliotheken, die durch ein dns-polymerisierungsverfahren produziert wurden
JP2006525811A (ja) 2003-05-16 2006-11-16 ロゼッタ インファーマティクス エルエルシー Ｒｎａ干渉の方法と組成物
CA2526810A1 (en) 2003-05-23 2005-04-21 Cold Spring Harbor Laboratory Virtual representations of nucleotide sequences
US20050181394A1 (en) * 2003-06-20 2005-08-18 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US20040259100A1 (en) * 2003-06-20 2004-12-23 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
WO2005003304A2 (en) 2003-06-20 2005-01-13 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
JP2007521003A (ja) * 2003-07-02 2007-08-02 ケイヘーネ・エヌ・ブイ スプライス部位ａｆｌｐ
US20050032102A1 (en) * 2003-07-22 2005-02-10 Affymetrix, Inc. Mapping genomic rearrangements
US8114978B2 (en) 2003-08-05 2012-02-14 Affymetrix, Inc. Methods for genotyping selected polymorphism
US7269517B2 (en) 2003-09-05 2007-09-11 Rosetta Inpharmatics Llc Computer systems and methods for analyzing experiment design
US9394565B2 (en) 2003-09-05 2016-07-19 Agena Bioscience, Inc. Allele-specific sequence variation analysis
JP2007507770A (ja) 2003-09-29 2007-03-29 パスワーク インフォーマティクス，インコーポレーテッド 生物学的特徴を検出するためのシステムおよび方法
CA2902980A1 (en) * 2004-03-08 2005-09-29 Rubicon Genomics, Inc. Methods and compositions for generating and amplifying dna libraries for sensitive detection and analysis of dna methylation
EP1574585A1 (en) * 2004-03-12 2005-09-14 Plant Research International B.V. Method for selective amplification of DNA fragments for genetic fingerprinting
CN101233240A (zh) 2004-03-26 2008-07-30 斯昆诺有限公司 与质量分析结合的甲基化特异性扩增产物的碱基特异性切割
US8192937B2 (en) * 2004-04-07 2012-06-05 Exiqon A/S Methods for quantification of microRNAs and small interfering RNAs
US8135595B2 (en) 2004-05-14 2012-03-13 H. Lee Moffitt Cancer Center And Research Institute, Inc. Computer systems and methods for providing health care
WO2005118877A2 (en) * 2004-06-02 2005-12-15 Vicus Bioscience, Llc Producing, cataloging and classifying sequence tags
EP1623996A1 (en) * 2004-08-06 2006-02-08 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Improved method of selecting a desired protein from a library
FR2876378B1 (fr) * 2004-10-08 2007-01-05 Univ Joseph Fourier Etablissem Amorces universelles et leur utilisation pour la detection et l'identification de vegetaux dans des melanges complexes
WO2007089610A1 (en) 2006-01-26 2007-08-09 Ceres, Inc. Modulating plant oil levels
US7335760B2 (en) 2004-12-22 2008-02-26 Ceres, Inc. Nucleic acid sequences encoding zinc finger proteins
US9505846B2 (en) 2005-01-28 2016-11-29 Life Technologies Corporation Multi-component inhibitors of nucleic acid polymerases
EP2301326A1 (en) 2005-03-03 2011-03-30 Rijk Zwaan Zaadteelt en Zaadhandel B.V. Near reverse breeding
WO2006094774A2 (en) 2005-03-03 2006-09-14 Rijk Zwaan Zaadteelt En Zaadhandel B.V. Reverse progeny mapping
US20060223066A1 (en) 2005-03-29 2006-10-05 Applera Corporation Methods for normalizing and for identifying small nucleic acids
US7452671B2 (en) 2005-04-29 2008-11-18 Affymetrix, Inc. Methods for genotyping with selective adaptor ligation
CA2612145A1 (en) * 2005-05-10 2006-11-16 Eric A. Johnson Methods of mapping polymorphisms and polymorphism microarrays
JP5331476B2 (ja) * 2005-06-15 2013-10-30 カリダ・ジェノミックス・インコーポレイテッド 遺伝子解析および化学解析用の単分子アレイ
CN105039313B (zh) 2005-06-23 2018-10-23 科因股份有限公司 用于多态性的高通量鉴定和检测的策略
CN101278058A (zh) * 2005-06-23 2008-10-01 科因股份有限公司 使用高通量测序技术对复杂基因组测序的改良策略
GB0514935D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Methods for sequencing a polynucleotide template
GB0514910D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Method for sequencing a polynucleotide template
US8409804B2 (en) 2005-08-02 2013-04-02 Rubicon Genomics, Inc. Isolation of CpG islands by thermal segregation and enzymatic selection-amplification method
ATE510930T1 (de) 2005-08-02 2011-06-15 Rubicon Genomics Inc Zusammensetzungen und verfahren zur bearbeitung und amplifikation von dna mit verwendung mehrerer enzyme in einer einzigen reaktion
US7622121B2 (en) 2005-09-21 2009-11-24 New York University Heat shock proteins from Mycobacterium leprae and uses thereof
US10316364B2 (en) 2005-09-29 2019-06-11 Keygene N.V. Method for identifying the source of an amplicon
AU2006295556B2 (en) 2005-09-29 2012-07-05 Keygene N.V. High throughput screening of mutagenized populations
WO2007044245A2 (en) 2005-10-07 2007-04-19 Callida Genomics, Inc. Self-assembled single molecule arrays and uses thereof
US7960104B2 (en) * 2005-10-07 2011-06-14 Callida Genomics, Inc. Self-assembled single molecule arrays and uses thereof
GB0522310D0 (en) 2005-11-01 2005-12-07 Solexa Ltd Methods of preparing libraries of template polynucleotides
US20080317741A1 (en) 2005-11-16 2008-12-25 Anu Kinnunen Biomarkers For Anti-Nogo-A Antibody Treatment in Spinal Cord Injury
GB0524069D0 (en) * 2005-11-25 2006-01-04 Solexa Ltd Preparation of templates for solid phase amplification
US8137936B2 (en) * 2005-11-29 2012-03-20 Macevicz Stephen C Selected amplification of polynucleotides
US11306351B2 (en) 2005-12-21 2022-04-19 Affymetrix, Inc. Methods for genotyping
ES2882401T3 (es) 2005-12-22 2021-12-01 Keygene Nv Método de detección de polimorfismos basado en AFLP de alto rendimiento
CA2641851A1 (en) 2006-02-08 2007-08-16 Eric Hans Vermaas Method for sequencing a polynucleotide template
EP1994180A4 (en) * 2006-02-24 2009-11-25 Callida Genomics Inc GENOME SEQUENCING ON DNA ARRAYS WITH HIGH THROUGHPUT
SG10201405158QA (en) * 2006-02-24 2014-10-30 Callida Genomics Inc High throughput genome sequencing on dna arrays
ES2301342B1 (es) * 2006-03-14 2009-05-01 Oryzon Genomics, S.A. "metodo de analisis de acidos nucleicos".
WO2007107710A1 (en) * 2006-03-17 2007-09-27 Solexa Limited Isothermal methods for creating clonal single molecule arrays
DK3239304T3 (da) * 2006-04-04 2020-10-26 Keygene Nv Højgennemløbsdetektering af molekylære markører baseret på AFLP og sekventering med højt gennemløb
US20130191941A1 (en) 2006-07-05 2013-07-25 Shing Kwok Modulating light response pathways in plants, increasing light-related tolerances in plants, and increasing biomass in plants
US8178300B2 (en) 2006-07-12 2012-05-15 Keygene N.V. Method for the identification of the clonal source of a restriction fragment
WO2008015396A2 (en) * 2006-07-31 2008-02-07 Solexa Limited Method of library preparation avoiding the formation of adaptor dimers
US7754429B2 (en) 2006-10-06 2010-07-13 Illumina Cambridge Limited Method for pair-wise sequencing a plurity of target polynucleotides
JP2010506597A (ja) 2006-10-18 2010-03-04 セミニス・ベジタブル・シーズ・インコーポレイテツド 増加したリコピン含有量を有するニンジン
WO2008070352A2 (en) 2006-10-27 2008-06-12 Complete Genomics, Inc. Efficient arrays of amplified polynucleotides
US20090105961A1 (en) * 2006-11-09 2009-04-23 Complete Genomics, Inc. Methods of nucleic acid identification in large-scale sequencing
US20090111705A1 (en) 2006-11-09 2009-04-30 Complete Genomics, Inc. Selection of dna adaptor orientation by hybrid capture
WO2008093098A2 (en) 2007-02-02 2008-08-07 Illumina Cambridge Limited Methods for indexing samples and sequencing multiple nucleotide templates
WO2008111453A1 (ja) * 2007-03-07 2008-09-18 The University Of Tokyo Dna断片の増幅方法
US20080293589A1 (en) * 2007-05-24 2008-11-27 Affymetrix, Inc. Multiplex locus specific amplification
AR066922A1 (es) 2007-06-08 2009-09-23 Monsanto Technology Llc Metodos de mejoramiento molecular del germoplasma de una planta por secuenciamiento dirigido
EA030862B1 (ru) 2007-07-09 2018-10-31 Байер Кропсайенс Н.В. Растение brassica, содержащее мутантные аллели (жирный ацил)-acp-тиоэстеразы
US9388457B2 (en) 2007-09-14 2016-07-12 Affymetrix, Inc. Locus specific amplification using array probes
US8951731B2 (en) * 2007-10-15 2015-02-10 Complete Genomics, Inc. Sequence analysis using decorated nucleic acids
US20090263872A1 (en) * 2008-01-23 2009-10-22 Complete Genomics Inc. Methods and compositions for preventing bias in amplification and sequencing reactions
US8415099B2 (en) 2007-11-05 2013-04-09 Complete Genomics, Inc. Efficient base determination in sequencing reactions
US8298768B2 (en) * 2007-11-29 2012-10-30 Complete Genomics, Inc. Efficient shotgun sequencing methods
US7897344B2 (en) * 2007-11-06 2011-03-01 Complete Genomics, Inc. Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs
US7901890B2 (en) * 2007-11-05 2011-03-08 Complete Genomics, Inc. Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation
US8518640B2 (en) * 2007-10-29 2013-08-27 Complete Genomics, Inc. Nucleic acid sequencing and process
EP2215455B1 (en) 2007-11-02 2014-03-05 Ceres, Inc. A method for formulating an NIR model used in biomass processing
NL2000992C2 (nl) 2007-11-09 2009-05-12 Nunhems Bv Nieuwe komkommerplanten met compacte groeiwijze.
CN103898125B (zh) 2007-11-28 2018-03-13 拜尔作物科学公司 包含突变indehiscent等位基因的芸苔属植物
US8592150B2 (en) 2007-12-05 2013-11-26 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
WO2009097368A2 (en) 2008-01-28 2009-08-06 Complete Genomics, Inc. Methods and compositions for efficient base calling in sequencing reactions
EP2255003B1 (en) 2008-02-15 2015-01-28 Ceres Inc. Drought and heat tolerance in plants
US12060554B2 (en) 2008-03-10 2024-08-13 Illumina, Inc. Method for selecting and amplifying polynucleotides
US9074244B2 (en) 2008-03-11 2015-07-07 Affymetrix, Inc. Array-based translocation and rearrangement assays
WO2009132028A1 (en) * 2008-04-21 2009-10-29 Complete Genomics, Inc. Array structures for nucleic acid detection
US9121074B2 (en) 2008-05-26 2015-09-01 Bayer Cropscience N.V. Gossypium hirsutum plants with increased fiber strength comprising a fiber strength allele spanning the GLUC1.1A gene from Gossypium barbadense
EP3156488B1 (en) 2008-07-17 2019-09-11 BASF Agricultural Solutions Seed US LLC Brassica plant comprising a mutant indehiscent allele
EP2172565A1 (en) * 2008-09-24 2010-04-07 Cyano Biotech GmbH Method of identifying and/or differentiating cyanophyta
EP2367937B1 (en) * 2008-12-04 2013-04-17 Keygene N.V. Method for the reduction of repetitive sequences in adapter-ligated restriction fragments
CN102272334B (zh) 2009-01-13 2014-08-20 关键基因股份有限公司 新基因组测序策略
US9868988B2 (en) 2009-03-13 2018-01-16 Cornell University Method to assess human allograft status from microrna expression levels
US8071865B2 (en) 2009-04-15 2011-12-06 Monsanto Technology Llc Plants and seeds of corn variety CV589782
US8071864B2 (en) 2009-04-15 2011-12-06 Monsanto Technology Llc Plants and seeds of corn variety CV897903
US8362332B2 (en) 2009-04-15 2013-01-29 Monsanto Technology Llc Plants and seeds of corn variety CV165560
EP2248914A1 (en) * 2009-05-05 2010-11-10 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. The use of class IIB restriction endonucleases in 2nd generation sequencing applications
US9524369B2 (en) 2009-06-15 2016-12-20 Complete Genomics, Inc. Processing and analysis of complex nucleic acid sequence data
CA2766190A1 (en) 2009-07-07 2011-01-13 Enza Zaden Beheer B.V. Cucumber vein yellowing virus (cvyv) resistant cucumber plants (cucumis sativus l.)
PL2659771T3 (pl) 2009-07-20 2019-05-31 Ceres Inc Rośliny transgeniczne o zwiększonej biomasie
US20110059453A1 (en) * 2009-08-23 2011-03-10 Affymetrix, Inc. Poly(A) Tail Length Measurement by PCR
CA2770389C (en) 2009-08-25 2015-12-29 Illumina, Inc. Methods for selecting and amplifying polynucleotides
WO2011071382A1 (en) * 2009-12-10 2011-06-16 Keygene N.V. Polymorfphic whole genome profiling
EP2333104A1 (en) 2009-12-11 2011-06-15 Lexogen GmbH RNA analytics method
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
CN102656279A (zh) 2009-12-17 2012-09-05 凯津公司 基于全基因组测序的限制性酶
EP2354243A1 (en) 2010-02-03 2011-08-10 Lexogen GmbH Complexity reduction method
US9746479B2 (en) 2010-03-09 2017-08-29 Cornell University Methods and compositions to predict and detect acute rejection
NL2004412C2 (en) 2010-03-16 2011-09-20 Nickerson Zwaan B V Male sterile leek plants.
MA34237B1 (fr) 2010-04-20 2013-05-02 Seminis Vegetables Seeds Inc Plantes contenant un caractere tige blanche
WO2011140329A1 (en) 2010-05-06 2011-11-10 Ceres, Inc. Transgenic plants having increased biomass
WO2011155833A2 (en) 2010-06-09 2011-12-15 Keygene N.V. Combinatorial sequence barcodes for high throughput screening
BR112013010278B1 (pt) 2010-10-27 2020-12-29 Ceres, Inc método para produzir uma planta, método para modular a composição de biomassa em uma planta, ácido nucleico isolado e método para alterar a composição de biomassa em uma planta
US8766054B2 (en) 2010-12-08 2014-07-01 Hm.Clause Phytophthora resistance in sweet peppers
EP2655629B1 (en) 2010-12-24 2024-04-24 BASF Agricultural Solutions Seed US LLC Brassica plant comprising a mutant alcatraz allele
AU2012205884A1 (en) 2011-01-14 2013-08-29 Keygene N.V. Paired end random sequence based genotyping
TWI465572B (zh) * 2011-05-19 2014-12-21 Univ Chang Gung Method, composition and system of amplification and detection of target microbial DNA
EP2729580B1 (en) 2011-07-08 2015-09-16 Keygene N.V. Sequence based genotyping based on oligonucleotide ligation assays
AU2012304328B2 (en) 2011-09-09 2017-07-20 The Board Of Trustees Of The Leland Stanford Junior University Methods for obtaining a sequence
BR122020026837B1 (pt) 2011-11-02 2021-04-13 Ceres, Inc Método de aumento do rendimento de planta em solo contendo níveis elevados de al3+, método de aumento da tolerância de uma planta
US10323256B2 (en) 2011-12-09 2019-06-18 Ceres, Inc. Transgenic plants having altered biomass composition
WO2013106737A1 (en) 2012-01-13 2013-07-18 Data2Bio Genotyping by next-generation sequencing
PT3363901T (pt) * 2012-02-17 2021-01-22 Hutchinson Fred Cancer Res Composições e métodos para identificar mutações com precisão
US11177020B2 (en) 2012-02-27 2021-11-16 The University Of North Carolina At Chapel Hill Methods and uses for molecular tags
WO2014006162A1 (en) 2012-07-06 2014-01-09 Bayer Cropscience Nv Brassica plants with modified seed oil composition
EP2870248A1 (en) 2012-07-06 2015-05-13 Bayer CropScience NV Brassica rod1 gene sequences and uses thereof
WO2014006159A1 (en) 2012-07-06 2014-01-09 Bayer Cropscience Nv Soybean rod1 gene sequences and uses thereof
EP2728013A1 (en) * 2012-10-31 2014-05-07 Universitätsspital Basel Method for the simultaneous amplification of a plurality of different nucleic acid target sequences
US9758828B2 (en) 2013-01-31 2017-09-12 Cornell University Methods to detect, treat and prevent acute cellular rejection in kidney allografts
PT2986727T (pt) 2013-04-19 2018-11-16 BASF Agricultural Solutions Seed US LLC Plantas de brassica híbridas e métodos para produção das mesmas
RU2549453C2 (ru) * 2013-04-26 2015-04-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" НАБОР СИНТЕТИЧЕСКИХ ОЛИГОНУКЛЕОТИДОВ ДЛЯ ВЫЯВЛЕНИЯ ВИДОВОЙ ПРИНАДЛЕЖНОСТИ ВЕРЕСКА ОБЫКНОВЕННОГО (Calluna vulgaris (L.) Hull.)
CN103233072B (zh) * 2013-05-06 2014-07-02 中国海洋大学 一种高通量全基因组dna甲基化检测技术
RU2535064C1 (ru) * 2013-05-30 2014-12-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" НАБОР СИНТЕТИЧЕСКИХ ОЛИГОНУКЛЕОТИДОВ ДЛЯ ВЫЯВЛЕНИЯ ВИДОВОЙ ПРИНАДЛЕЖНОСТИ СВОБОДНОЯГОДНИКА КОЛЮЧЕГО, ЭЛЕУТЕРОКОККА (Eleutherococcus senticocus (Rupr. et Maxim.) Maxim.)
RU2535063C1 (ru) * 2013-05-30 2014-12-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" НАБОР СИНТЕТИЧЕCКИХ ОЛИГОНУКЛЕОТИДОВ ДЛЯ ВЫЯВЛЕНИЯ ВИДОВОЙ ПРИНАДЛЕЖНОСТИ СУШЕНИЦЫ БОЛОТНОЙ (Filaginella uliginosa (L.) Opiz)
RU2535060C1 (ru) * 2013-05-30 2014-12-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" НАБОР СИНТЕТИЧЕСКИХ ОЛИГОНУКЛЕОТИДОВ ДЛЯ ВЫЯВЛЕНИЯ ВИДОВОЙ ПРИНАДЛЕЖНОСТИ АРАЛИИ ВЫСОКОЙ (Aralia elata (Miq.) Seem.)
US9982301B2 (en) 2014-01-07 2018-05-29 Cornell University Urine mRNA profile and acute dysfunction of kidney allograft
KR20160113177A (ko) 2014-01-22 2016-09-28 라이프 테크놀로지스 코포레이션 고온 핵산 합성에서 이용하기 위한 신규한 역전사효소
US20140245471A1 (en) 2014-05-02 2014-08-28 Nunhems B.V. Carrot plants with a high anthocyanin level
US9107356B2 (en) 2014-05-02 2015-08-18 Nunhems B.V. Hybrid carrot variety NUN 85931
EP3169785B1 (en) 2014-07-15 2021-09-15 Ceres, Inc. Methods of increasing crop yield under abiotic stress
RU2573937C1 (ru) * 2014-10-20 2016-01-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" НАБОР СИНТЕТИЧЕСКИХ ОЛИГОНУКЛЕОТИДОВ ДЛЯ ВЫЯВЛЕНИЯ ВИДОВОЙ ПРИНАДЛЕЖНОСТИ ВОЛОДУШКИ МНОГОЖИЛЬЧАТОЙ (Bupleurum multinerve DC.)
CA2966065A1 (en) 2014-10-30 2016-05-06 Nunhems B.V. Lettuce plants comprising resistance against nasonovia ribisnigri biotype 1
CN107624135A (zh) 2015-04-28 2018-01-23 拜尔作物科学公司 具有修饰的种子油组成的芸苔属植物
JP6978152B2 (ja) 2015-09-04 2021-12-08 キージーン ナムローゼ フェンノートシャップ 複相胞子生殖遺伝子
US10226015B2 (en) 2015-11-10 2019-03-12 Pop Vriend Research B.V. Peronospora resistance in Spinacia sp
US11277983B2 (en) 2015-11-10 2022-03-22 Pop Vriend Seeds Bv Peronospora resistance in spinacia sp
WO2018091438A1 (en) 2016-11-17 2018-05-24 Nunhems B.V. Multibranching artichoke plant
US11584958B2 (en) 2017-03-31 2023-02-21 Grail, Llc Library preparation and use thereof for sequencing based error correction and/or variant identification
WO2019068647A1 (en) 2017-10-04 2019-04-11 Hild Samen Gmbh TOTAL RESISTANCE TO THE MILDIOU IN THE BASIL
EP3737690A1 (en) 2018-01-12 2020-11-18 Basf Se Gene underlying the number of spikelets per spike qtl in wheat on chromosome 7a
WO2019145447A1 (en) 2018-01-26 2019-08-01 Nunhems B.V. Spinach plants resistant to at least peronospora farinosa races 8, 9, 11, 13 and 16
AU2019390691A1 (en) 2018-11-28 2021-05-13 Keygene N.V. Targeted enrichment by endonuclease protection
WO2020120242A1 (en) 2018-12-13 2020-06-18 Nunhems B.V. Solanaceous plant capable of stenospermocarpic fruit formation
CN113474466A (zh) 2019-02-21 2021-10-01 主基因有限公司 多倍体基因分型
WO2020239984A1 (en) 2019-05-29 2020-12-03 Keygene N.V. Gene for parthenogenesis
AU2020291144A1 (en) 2019-06-13 2022-02-10 Nunhems B.V. Tomato plant producing fruit having improved ripening characteristics
JP2023504022A (ja) 2019-11-26 2023-02-01 ヌンヘムス、ベスローテン、フェンノートシャップ タマネギにおける低減ピルベートレベル形質に関する分子マーカー
EP4073245A1 (en) 2019-12-12 2022-10-19 Keygene N.V. Semi-solid state nucleic acid manipulation
EP4077661A1 (en) 2019-12-20 2022-10-26 Keygene N.V. Ngs library preparation using covalently closed nucleic acid molecule ends
CN116056566B (zh) 2020-04-23 2024-06-25 纽海姆有限公司 具有改进的烟草花叶病毒抗性的番茄植物
IL298023A (en) 2020-05-13 2023-01-01 Nunhems Bv Tomato plants with suppressed meiotic recombination
US20230232762A1 (en) 2020-06-10 2023-07-27 Nunhems B.V. Capsicum annuum plants having improved thrips resistance
US20230407366A1 (en) 2020-10-06 2023-12-21 Keygene N.V. Targeted sequence addition
CN116568131A (zh) 2020-10-13 2023-08-08 主基因有限公司 单性生殖基因的修饰的启动子
WO2022112316A1 (en) 2020-11-24 2022-06-02 Keygene N.V. Targeted enrichment using nanopore selective sequencing
WO2022140762A1 (en) 2020-12-21 2022-06-30 BASF Agricultural Solutions Seed US LLC Brassica napus plants comprising an improved fertility restorer
WO2022144003A1 (zh) * 2020-12-31 2022-07-07 东科智生基因科技（北京）有限公司 一种用于高通量靶向测序的多重pcr文库构建方法
WO2022265965A1 (en) 2021-06-14 2022-12-22 10X Genomics, Inc. Reverse transcriptase variants for improved performance
CA3225922A1 (en) 2021-07-23 2023-01-26 BASF Agricultural Solutions Seed US LLC Blackleg resistant plants and methods for the identification of blackleg resistant plants
US12004476B2 (en) 2022-01-26 2024-06-11 Monsanto Technology Llc. Cotton variety 20R750B3XF
WO2024121354A1 (en) 2022-12-08 2024-06-13 Keygene N.V. Duplex sequencing with covalently closed dna ends
WO2024146898A1 (en) 2023-01-03 2024-07-11 Keygene N.V. Nal1 in rice

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4321365A (en) * 1977-10-19 1982-03-23 Research Corporation Oligonucleotides useful as adaptors in DNA cloning, adapted DNA molecules, and methods of preparing adaptors and adapted molecules
US5093245A (en) * 1988-01-26 1992-03-03 Applied Biosystems Labeling by simultaneous ligation and restriction
WO1990008821A1 (en) * 1989-01-31 1990-08-09 University Of Miami Microdissection and amplification of chromosomal dna
AU5640090A (en) * 1989-03-21 1990-11-05 Collaborative Research Inc. A dna diagnostic test using an exonuclease activity
JPH05508305A (ja) * 1989-10-16 1993-11-25 ジエネラブス・テクノロジーズ・インコーポレイテツド 非特異的ｄｎａ増幅
WO1991014003A2 (en) * 1990-03-09 1991-09-19 Ig Laboratories, Inc. Characterization and analysis of polymorphic vntr loci
US5126239A (en) * 1990-03-14 1992-06-30 E. I. Du Pont De Nemours And Company Process for detecting polymorphisms on the basis of nucleotide differences
WO1992007095A1 (en) * 1990-10-15 1992-04-30 Stratagene Arbitrarily primed polymerase chain reaction method for fingerprinting genomes
AU1426392A (en) * 1991-01-22 1992-08-27 Board Of Regents, The University Of Texas System 5' and 3' polymerase chain reaction walking from known dna sequences

Also Published As

Publication number Publication date
EP0534858B1 (en) 2000-04-05
HUT68504A (en) 1995-06-28
IL103267A (en) 2004-07-25
JP4088403B2 (ja) 2008-05-21
FI20031526A (fi) 2003-10-17
FI941360A (fi) 1994-05-24
FI941360A0 (fi) 1994-03-24
WO1993006239A1 (en) 1993-04-01
GR3033895T3 (en) 2000-11-30
US6045994A (en) 2000-04-04
CZ298187B6 (cs) 2007-07-18
DE69230873T2 (de) 2000-11-09
DE69233719T2 (de) 2009-01-02
ES2299229T3 (es) 2008-05-16
DE69230873D1 (de) 2000-05-11
DE69230873T3 (de) 2006-04-06
NO318016B1 (no) 2005-01-24
AU672760B2 (en) 1996-10-17
ES2147550T3 (es) 2000-09-16
JPH06510668A (ja) 1994-12-01
CA2119557C (en) 2004-02-24
CZ66994A3 (en) 1994-12-15
JP2001061486A (ja) 2001-03-13
ES2147550T5 (es) 2005-11-01
NO941064L (no) 1994-05-20
RU94033149A (ru) 1996-07-27
PT534858E (pt) 2000-09-29
ATE382094T1 (de) 2008-01-15
DE69233719D1 (de) 2008-02-07
KR100321510B1 (ko) 2005-01-10
HU223760B1 (hu) 2005-01-28
JP2008131947A (ja) 2008-06-12
NO941064D0 (no) 1994-03-23
JP3236295B2 (ja) 2001-12-10
FI115402B (fi) 2005-04-29
EP0969102B1 (en) 2007-12-26
DK0534858T3 (da) 2000-09-11
JP4385072B2 (ja) 2009-12-16
AU2662992A (en) 1993-04-27
HU9400809D0 (en) 1994-06-28
ATE191510T1 (de) 2000-04-15
RU2182176C2 (ru) 2002-05-10
IL103267A0 (en) 1993-02-21
EP0969102A3 (en) 2000-02-23
CA2119557A1 (en) 1993-04-01
ZA927323B (en) 1993-08-30
CZ291877B6 (cs) 2003-06-18
EP0534858A1 (en) 1993-03-31
FI113184B (fi) 2004-03-15
DK0969102T3 (da) 2008-05-13
EP0534858B2 (en) 2005-04-27
DK0534858T4 (da) 2005-08-08
EP0969102A2 (en) 2000-01-05

Similar Documents

Publication Publication Date Title
PT969102E (pt) Iniciadores, grupos e conjuntos de fragmentos de restrição usados na amplificação selectiva de fragmentos de restrição
PT84207B (pt) Processo para a expressao de genes em plantas, fragmentos de adn, plasmideos e microrganismos transformados
DE69636080D1 (de) Eine in Kaskaden verlaufende Vervielfältigungsreaktion von Nukleinsäuren
EP0329822A3 (en) Nucleic acid amplification process
NO873753D0 (no) Periodisk biologisk luftbehandlingsprosess og system for denne.
DE69331665D1 (de) Methode zur behandlung von nukleinsäureproben
DE69029105D1 (de) Schnellverfahren zum Nachweis und/oder zur Identifizierung einer Einzelbase in einer Nukleinsäuresequenz und seine Verwendungen
DE69329636D1 (de) Verfahren zur Vervielfältigung von Nukleinsäuresequenzen
PT592836E (pt) Adn do local de integracao do virus adeno-associado humano e suas utilizacoes
DE59609841D1 (de) Verfahren zur Gattungs- und speziesspezifische Identifizierung von Legionellen
BR8108073A (pt) Sequencias de dna;plasmidios recombinantes;cultura bacteriana;e processo para a producao de preprotaumatina,pretaumatina ou protaumatina
DE59709012D1 (de) Verwendung von primern für universelle fingerprint-analysen
ES2063206T3 (es) Procedimiento para secuenciacion de acidos desoxirribonucleicos.
ATE108834T1 (de) Spezifische nukleinsäurefragmente des menschlichen villingens, ihre anwendung für diagnostische zwecke.
NO892990D0 (no) Midler og metode for oekning av nukleinsyrehybridisering.
DE3865707D1 (de) Zusammensetzungen, bestimmt zur holzbehandlung und verfahren zur holzbehandlung.