CA2119557A1 - Selective restriction fragment amplification: a general method for dna fingerprinting - Google Patents

Selective restriction fragment amplification: a general method for dna fingerprinting

Info

Publication number
CA2119557A1
CA2119557A1 CA002119557A CA2119557A CA2119557A1 CA 2119557 A1 CA2119557 A1 CA 2119557A1 CA 002119557 A CA002119557 A CA 002119557A CA 2119557 A CA2119557 A CA 2119557A CA 2119557 A1 CA2119557 A1 CA 2119557A1
Authority
CA
Canada
Prior art keywords
restriction fragment
general method
dna fingerprinting
fragment amplification
selective restriction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002119557A
Other languages
French (fr)
Other versions
CA2119557C (en
Inventor
Marc Zabeau
Pieter Vos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Keygene NV
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8208616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2119557(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2119557A1 publication Critical patent/CA2119557A1/en
Application granted granted Critical
Publication of CA2119557C publication Critical patent/CA2119557C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Dental Preparations (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
  • Auxiliary Devices For Music (AREA)
  • Reverberation, Karaoke And Other Acoustics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Power Conversion In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)

Abstract

The invention relates to a process for the controlled amplification of at least one part of a starting DNA containing a plurality of restriction sites for a determined specific restriction endonuclease, and of which at least part of its nucleic acid is unknown. Application of this process to human, animal or plant DNA
fingerprinting, to identification of restriction fragment length polymorphisms. Kit for the application of the process.
CA002119557A 1991-09-24 1992-09-24 Selective restriction fragment amplification: a general method for dna fingerprinting Expired - Lifetime CA2119557C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP91402542.4 1991-09-24
EP91402542 1991-09-24
PCT/EP1992/002216 WO1993006239A1 (en) 1991-09-24 1992-09-24 Selective restriction fragment amplification: a general method for dna fingerprinting

Publications (2)

Publication Number Publication Date
CA2119557A1 true CA2119557A1 (en) 1993-04-01
CA2119557C CA2119557C (en) 2004-02-24

Family

ID=8208616

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002119557A Expired - Lifetime CA2119557C (en) 1991-09-24 1992-09-24 Selective restriction fragment amplification: a general method for dna fingerprinting

Country Status (20)

Country Link
US (1) US6045994A (en)
EP (2) EP0534858B2 (en)
JP (3) JP3236295B2 (en)
KR (1) KR100321510B1 (en)
AT (2) ATE382094T1 (en)
AU (1) AU672760B2 (en)
CA (1) CA2119557C (en)
CZ (2) CZ291877B6 (en)
DE (2) DE69230873T3 (en)
DK (2) DK0969102T3 (en)
ES (2) ES2299229T3 (en)
FI (2) FI113184B (en)
GR (1) GR3033895T3 (en)
HU (1) HU223760B1 (en)
IL (1) IL103267A (en)
NO (1) NO318016B1 (en)
PT (2) PT534858E (en)
RU (1) RU2182176C2 (en)
WO (1) WO1993006239A1 (en)
ZA (1) ZA927323B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7956239B2 (en) 2001-06-07 2011-06-07 Pioneer Hi-Bred International, Inc. QTL controlling Sclerotinia stem ROT resistance in soybean

Families Citing this family (283)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6074818A (en) * 1990-08-24 2000-06-13 The University Of Tennessee Research Corporation Fingerprinting of nucleic acids, products and methods
US20100267023A1 (en) * 1992-09-24 2010-10-21 Keygene N.V. Selective restriction fragment amplification: fingerprinting
US7026115B1 (en) 1991-09-24 2006-04-11 Keygene N.V. Selective restriction fragment amplification: fingerprinting
ZA929319B (en) * 1991-12-11 1993-05-24 Igen Inc Method for exponential amplification of nucleic acid by a single unpaired primer.
DE69333650T2 (en) * 1992-02-19 2006-01-12 The Public Health Research Institute Of The City Of New York, Inc. NEW ARRANGEMENT OF OLIGONUCLEOTIDES AND THEIR BENEFITS FOR SORTING, ISOLATING, SEQUENCING AND MANIPULATING NUCLEIC ACIDS
GB9301776D0 (en) * 1993-01-29 1993-03-17 Univ Alberta Method for detecting genomic variation
US5422252A (en) * 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
US5470723A (en) * 1993-05-05 1995-11-28 Becton, Dickinson And Company Detection of mycobacteria by multiplex nucleic acid amplification
US5650274A (en) * 1993-06-25 1997-07-22 Hitachi, Ltd. DNA analyzing method
GB2283568B (en) * 1993-10-13 1997-12-24 Mini Agriculture & Fisheries Identification of fruit juice components
RU2111254C1 (en) * 1994-07-11 1998-05-20 Институт молекулярной биологии им.В.А.Энгельгардта РАН Method of detection of differentially expressing template rnas and cloning the corresponding cdna fragments
US5710000A (en) 1994-09-16 1998-01-20 Affymetrix, Inc. Capturing sequences adjacent to Type-IIs restriction sites for genomic library mapping
GB2295011A (en) * 1994-11-10 1996-05-15 Unilever Plc Selection of DNA markers using adaptor molecules
GB2295228A (en) * 1994-11-10 1996-05-22 Unilever Plc Selective amplification of DNA having a plurality of sites for a specific endonuclease
AU704660B2 (en) * 1994-11-28 1999-04-29 E.I. Du Pont De Nemours And Company Compound microsatellite primers for the detection of genetic polymorphisms
EP0718409A3 (en) * 1994-12-22 1999-02-03 Hitachi, Ltd. DNA preparation method
EP0721987A1 (en) * 1995-01-16 1996-07-17 Keygene N.V. Amplification of simple sequence repeats
US6031153A (en) * 1995-01-23 2000-02-29 Novartis Ag Method for protecting plants
US5565340A (en) * 1995-01-27 1996-10-15 Clontech Laboratories, Inc. Method for suppressing DNA fragment amplification during PCR
EP0735144B1 (en) * 1995-03-28 2002-06-05 Japan Science and Technology Corporation Method for molecular indexing of genes using restriction enzymes
US6395887B1 (en) 1995-08-01 2002-05-28 Yale University Analysis of gene expression by display of 3'-end fragments of CDNAS
US5712126A (en) * 1995-08-01 1998-01-27 Yale University Analysis of gene expression by display of 3-end restriction fragments of CDNA
EP0843727A2 (en) * 1995-08-07 1998-05-27 Keygene N.V. Resistance against wilt inducing fungi
US6418382B2 (en) 1995-10-24 2002-07-09 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US5972693A (en) * 1995-10-24 1999-10-26 Curagen Corporation Apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US5871697A (en) 1995-10-24 1999-02-16 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US6218119B1 (en) 1996-01-16 2001-04-17 Keygene, N. V. Amplification of simple sequence repeats
AU2264197A (en) * 1996-02-09 1997-08-28 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Restriction display (rd-pcr) of differentially expressed mrnas
US6091004A (en) * 1996-06-21 2000-07-18 Novartis Finance Corporation Gene encoding a protein involved in the signal transduction cascade leading to systemic acquired resistance in plants
EP0823481A1 (en) 1996-08-09 1998-02-11 Keygene N.V. Resistance against nematodes
DK0937155T3 (en) 1996-08-09 2005-01-31 Keygene Nv Resistance to nematodes and / or aphids
AU4065397A (en) 1996-08-14 1998-03-06 Life Technologies, Inc. Stable compositions for nucleic acid amplification and sequencing
EP1007730A4 (en) * 1996-08-30 2004-04-28 Invitrogen Corp METHODS FOR IDENTIFICATION AND ISOLATION OF SPECIFIC NUCLEOTIDE SEQUENCES IN cDNA AND GENOMIC DNA
US20040142327A1 (en) * 1996-11-22 2004-07-22 Jhy-Jhu Lin Methods for identifying and isolating DNA polymorphisms or genetic markers
US5986082A (en) * 1996-12-13 1999-11-16 Novartis Ag Altered forms of the NIM1 gene conferring disease resistance in plants
US5861295A (en) 1997-01-02 1999-01-19 Life Technologies, Inc. Nucleic acid-free thermostable enzymes and methods of production thereof
WO1998030721A1 (en) * 1997-01-10 1998-07-16 Pioneer Hi-Bred International, Inc. Hybridization-based genetic amplification and analysis
US6306588B1 (en) 1997-02-07 2001-10-23 Invitrogen Corporation Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof
EP3034626A1 (en) 1997-04-01 2016-06-22 Illumina Cambridge Limited Method of nucleic acid sequencing
US6090556A (en) * 1997-04-07 2000-07-18 Japan Science & Technology Corporation Method for quantitatively determining the expression of a gene
EP2184289A1 (en) 1997-04-22 2010-05-12 Life Technologies Corporation Methods for the production of ASLV reverse transcriptases composed of multiple subunits
WO1999007896A2 (en) 1997-08-07 1999-02-18 Curagen Corporation Detection and confirmation of nucleic acid sequences by use of oligonucleotides comprising a subsequence hybridizing exactly to a known terminal sequence and a subsequence hybridizing to an unidentified sequence
US6673577B1 (en) * 1997-08-07 2004-01-06 Curagen Corporation Detection and confirmation of nucleic acid sequences by use of poisoning oligonucleotides
US6833242B2 (en) * 1997-09-23 2004-12-21 California Institute Of Technology Methods for detecting and sorting polynucleotides based on size
WO1999023256A1 (en) * 1997-10-30 1999-05-14 Cold Spring Harbor Laboratory Probe arrays and methods of using probe arrays for distinguishing dna
JP2002501760A (en) * 1998-02-02 2002-01-22 アマーシャム・ファルマシア・バイオテック・アクチボラグ Nucleic acid analysis method
WO1999053100A2 (en) 1998-04-16 1999-10-21 Case Western Reserve University Method for finding genetic markers of somaclonal variation
US6324479B1 (en) 1998-05-08 2001-11-27 Rosetta Impharmatics, Inc. Methods of determining protein activity levels using gene expression profiles
US6218122B1 (en) 1998-06-19 2001-04-17 Rosetta Inpharmatics, Inc. Methods of monitoring disease states and therapies using gene expression profiles
ATE236997T1 (en) * 1998-07-21 2003-04-15 Keygene Nv IMPROVED PRIMERS FOR AFLP AMPLIFICATION
DE69816286T2 (en) 1998-07-29 2004-05-27 Keygene N.V. Method for the detection of nucleic acid methylations by AFLP
US6306593B1 (en) * 1998-09-17 2001-10-23 Union Camp Corporation Selective AFLP primers for reduction of complexity of maker genotyping and DNA markers for loblolly pine identified using the AFLP primers
US6146830A (en) 1998-09-23 2000-11-14 Rosetta Inpharmatics, Inc. Method for determining the presence of a number of primary targets of a drug
US6703228B1 (en) 1998-09-25 2004-03-09 Massachusetts Institute Of Technology Methods and products related to genotyping and DNA analysis
JP3855492B2 (en) * 1998-10-08 2006-12-13 株式会社日立製作所 Mixed nucleic acid fragment analysis
WO2000021358A1 (en) 1998-10-14 2000-04-20 Agriculture And Agri-Food Canada Hybrid alfalfa (medicago sativa)
US6950752B1 (en) 1998-10-27 2005-09-27 Rosetta Inpharmatics Llc Methods for removing artifact from biological profiles
US6203987B1 (en) 1998-10-27 2001-03-20 Rosetta Inpharmatics, Inc. Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns
US6468476B1 (en) 1998-10-27 2002-10-22 Rosetta Inpharmatics, Inc. Methods for using-co-regulated genesets to enhance detection and classification of gene expression patterns
DE69929542T2 (en) * 1998-10-27 2006-09-14 Affymetrix, Inc., Santa Clara COMPLEXITY MANAGEMENT AND ANALYSIS OF GENOMIC DNA
ATE274069T1 (en) * 1998-11-09 2004-09-15 Methexis Genomics N V ANALYSIS OF BAMPLICONS OBTAINED BY RESTRICTION ENDONUCLEASE
US6801859B1 (en) 1998-12-23 2004-10-05 Rosetta Inpharmatics Llc Methods of characterizing drug activities using consensus profiles
US6222093B1 (en) 1998-12-28 2001-04-24 Rosetta Inpharmatics, Inc. Methods for determining therapeutic index from gene expression profiles
US6370478B1 (en) 1998-12-28 2002-04-09 Rosetta Inpharmatics, Inc. Methods for drug interaction prediction using biological response profiles
US6605432B1 (en) * 1999-02-05 2003-08-12 Curators Of The University Of Missouri High-throughput methods for detecting DNA methylation
US6630333B1 (en) 1999-03-23 2003-10-07 Invitrogen Corporation Substantially pure reverse transriptases and methods of production thereof
AU773854B2 (en) * 1999-04-09 2004-06-10 Keygene N.V. Method for the detection and/or analysis, by means of primer extension techniques, of single nucleotide polymorphisms in restriction fragments, in particular in amplified restriction fragments generated using AFLP
US6994969B1 (en) 1999-04-30 2006-02-07 Methexis Genomics, N.V. Diagnostic sequencing by a combination of specific cleavage and mass spectrometry
US20020119448A1 (en) * 1999-06-23 2002-08-29 Joseph A. Sorge Methods of enriching for and identifying polymorphisms
JP3969091B2 (en) 1999-06-23 2007-08-29 株式会社日立製作所 Centrifuge and sample preparation apparatus using the same
US6420117B1 (en) 1999-09-14 2002-07-16 The University Of Georgia Research Foundation, Inc. Miniature inverted repeat transposable elements and methods of use
US6221600B1 (en) * 1999-10-08 2001-04-24 Board Of Regents, The University Of Texas System Combinatorial oligonucleotide PCR: a method for rapid, global expression analysis
US6958225B2 (en) 1999-10-27 2005-10-25 Affymetrix, Inc. Complexity management of genomic DNA
AUPQ439699A0 (en) * 1999-12-01 1999-12-23 University Of Sydney, The Detection of nucleic acid fragments
US7166429B2 (en) 1999-12-29 2007-01-23 Keygene N.V. Method for generating oligonucleotides, in particular for the detection of amplified restriction fragments obtained using AFLP®
AU2001254670A1 (en) * 2000-03-02 2001-09-12 Akzo Nobel N.V. Detection of hepatitis b virus rna
AU6052001A (en) 2000-03-29 2001-10-08 Ct For The Applic Of Molecular Methods for genotyping by hybridization analysis
AU2001258924A1 (en) * 2000-05-15 2001-11-26 Keygene N.V. Microsatellite-aflp
WO2001092500A1 (en) 2000-05-26 2001-12-06 Invitrogen Corporation Thermostable reverse transcriptases and uses thereof
US20040209276A1 (en) 2002-09-13 2004-10-21 Smith Michael D. Thermostable reverse transcriptases and uses thereof
US7078208B2 (en) 2000-05-26 2006-07-18 Invitrogen Corporation Thermostable reverse transcriptases and uses thereof
WO2002002740A2 (en) 2000-07-05 2002-01-10 Rosetta Inpharmatics, Inc. Methods and compositions for determining gene function
US6984522B2 (en) 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
AR031640A1 (en) * 2000-12-08 2003-09-24 Applied Research Systems ISOTHERMAL AMPLIFICATION OF NUCLEIC ACIDS IN A SOLID SUPPORT
US20030143554A1 (en) * 2001-03-31 2003-07-31 Berres Mark E. Method of genotyping by determination of allele copy number
AU2002307152A1 (en) * 2001-04-06 2002-10-21 California Institute Of Technology Nucleic acid amplification utilizing microfluidic devices
EP1386002A4 (en) 2001-04-16 2006-11-08 Applera Corp Methods and compositions for nucleotide analysis
WO2002086169A1 (en) * 2001-04-23 2002-10-31 Dana-Farber Cancer Institute, Inc. Methods for rapid screening of polymorphisms, mutations and methylation
US20030044785A1 (en) * 2001-05-01 2003-03-06 American Type Culture Collection Method for identifying and genotyping microorganisms
GB0114853D0 (en) * 2001-06-18 2001-08-08 Medical Res Council Happier Mapping
WO2003002716A2 (en) 2001-06-28 2003-01-09 Mountain View Pharmaceuticals, Inc. Polymer stabilized proteinases
WO2003010516A1 (en) * 2001-07-23 2003-02-06 Curagen Corporation Method for identifying a nucleic acid sequence
US6872529B2 (en) * 2001-07-25 2005-03-29 Affymetrix, Inc. Complexity management of genomic DNA
CA2467577A1 (en) * 2001-11-19 2003-05-30 Parallele Bioscience, Inc. Multiplex pcr
US20110151438A9 (en) 2001-11-19 2011-06-23 Affymetrix, Inc. Methods of Analysis of Methylation
AU2002358110A1 (en) * 2001-12-10 2003-07-09 Novartis Ag Methods of treating psychosis and schizophrenia based on a polymorphism in the ctf gene
US7418351B2 (en) 2002-01-31 2008-08-26 Rosetta Inpharmatics Llc Methods for analysis of measurement errors in measured signals
WO2003065282A1 (en) 2002-02-01 2003-08-07 Rosetta Inpharmatics Llc Computer systems and methods for identifying genes and determining pathways associated with traits
AU2003208480A1 (en) * 2002-03-05 2003-09-16 Lynx Therapeutics INC. Methods for detecting genome-wide sequence variations associated with a phenotype
US20040110166A1 (en) * 2002-03-07 2004-06-10 Macevicz Stephen C. Genome-wide scanning of genetic polymorphisms
AU2003224817B2 (en) 2002-04-01 2008-11-06 Fluidigm Corporation Microfluidic particle-analysis systems
WO2003087774A2 (en) 2002-04-12 2003-10-23 Curators Of The University Of Missouri Ecist microarrays for dual screening of dna hypermethylation and gene silencing
US7115370B2 (en) * 2002-06-05 2006-10-03 Capital Genomix, Inc. Combinatorial oligonucleotide PCR
US9388459B2 (en) 2002-06-17 2016-07-12 Affymetrix, Inc. Methods for genotyping
US20040072217A1 (en) * 2002-06-17 2004-04-15 Affymetrix, Inc. Methods of analysis of linkage disequilibrium
ES2380929T3 (en) 2002-08-22 2012-05-21 Novartis Ag Diagnosis of chronic rejection
EP2213615A3 (en) 2002-09-25 2012-02-29 California Institute of Technology Microfluidic Large Scale Integration
WO2004040001A2 (en) 2002-10-02 2004-05-13 California Institute Of Technology Microfluidic nucleic acid analysis
US7459273B2 (en) * 2002-10-04 2008-12-02 Affymetrix, Inc. Methods for genotyping selected polymorphism
US20040219565A1 (en) 2002-10-21 2004-11-04 Sakari Kauppinen Oligonucleotides useful for detecting and analyzing nucleic acids of interest
WO2004076683A2 (en) * 2003-02-26 2004-09-10 Callida Genomics, Inc. Random array dna analysis by hybridization
EP1581661B1 (en) * 2003-01-10 2012-09-12 Keygene N.V. Aflp-based method for integrating physical and genetic maps
US7996155B2 (en) 2003-01-22 2011-08-09 Microsoft Corporation ANOVA method for data analysis
WO2005003375A2 (en) * 2003-01-29 2005-01-13 454 Corporation Methods of amplifying and sequencing nucleic acids
DE602004029560D1 (en) * 2003-03-07 2010-11-25 Rubicon Genomics Inc AMPLIFICATION AND ANALYSIS OF TOTAL GENOME AND TOTAL TRANSCRIPTIBLE LIBRARIES PRODUCED BY A DNA POLYMERIZATION PROCEDURE
US8206913B1 (en) 2003-03-07 2012-06-26 Rubicon Genomics, Inc. Amplification and analysis of whole genome and whole transcriptome libraries generated by a DNA polymerization process
CA2525619A1 (en) 2003-05-16 2005-03-03 Rosetta Inpharmatics, Llc Methods and compositions for rna interference
JP2006525814A (en) 2003-05-23 2006-11-16 コールド スプリング ハーバー ラボラトリー Substantial representation of nucleotide sequence
US20040259100A1 (en) * 2003-06-20 2004-12-23 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US20050181394A1 (en) * 2003-06-20 2005-08-18 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US9045796B2 (en) * 2003-06-20 2015-06-02 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
JP2007521003A (en) * 2003-07-02 2007-08-02 ケイヘーネ・エヌ・ブイ Splice site AFLP
US20050032102A1 (en) * 2003-07-22 2005-02-10 Affymetrix, Inc. Mapping genomic rearrangements
US8114978B2 (en) 2003-08-05 2012-02-14 Affymetrix, Inc. Methods for genotyping selected polymorphism
US7269517B2 (en) 2003-09-05 2007-09-11 Rosetta Inpharmatics Llc Computer systems and methods for analyzing experiment design
US9394565B2 (en) 2003-09-05 2016-07-19 Agena Bioscience, Inc. Allele-specific sequence variation analysis
EP2469439A2 (en) 2003-09-29 2012-06-27 Pathwork Diagnostics, Inc. Systems and methods for detecting biological features
CA2902980A1 (en) 2004-03-08 2005-09-29 Rubicon Genomics, Inc. Methods and compositions for generating and amplifying dna libraries for sensitive detection and analysis of dna methylation
EP1574585A1 (en) * 2004-03-12 2005-09-14 Plant Research International B.V. Method for selective amplification of DNA fragments for genetic fingerprinting
AU2005230936B2 (en) 2004-03-26 2010-08-05 Agena Bioscience, Inc. Base specific cleavage of methylation-specific amplification products in combination with mass analysis
US8192937B2 (en) * 2004-04-07 2012-06-05 Exiqon A/S Methods for quantification of microRNAs and small interfering RNAs
US8135595B2 (en) 2004-05-14 2012-03-13 H. Lee Moffitt Cancer Center And Research Institute, Inc. Computer systems and methods for providing health care
US7618778B2 (en) * 2004-06-02 2009-11-17 Kaufman Joseph C Producing, cataloging and classifying sequence tags
EP1623996A1 (en) * 2004-08-06 2006-02-08 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Improved method of selecting a desired protein from a library
FR2876378B1 (en) * 2004-10-08 2007-01-05 Univ Joseph Fourier Etablissem UNIVERSAL PRIMERS AND THEIR USE FOR THE DETECTION AND IDENTIFICATION OF PLANTS IN COMPLEX MIXTURES
US7335760B2 (en) 2004-12-22 2008-02-26 Ceres, Inc. Nucleic acid sequences encoding zinc finger proteins
US9505846B2 (en) 2005-01-28 2016-11-29 Life Technologies Corporation Multi-component inhibitors of nucleic acid polymerases
CA2598737C (en) 2005-03-03 2015-05-12 Rijk Zwaan Zaadteelt En Zaadhandel B.V. Reverse progeny mapping
CN104782475A (en) 2005-03-03 2015-07-22 瑞克斯旺种苗集团公司 Near reverse breeding
US20060223066A1 (en) * 2005-03-29 2006-10-05 Applera Corporation Methods for normalizing and for identifying small nucleic acids
US7452671B2 (en) 2005-04-29 2008-11-18 Affymetrix, Inc. Methods for genotyping with selective adaptor ligation
WO2006122215A2 (en) * 2005-05-10 2006-11-16 State Of Oregon Acting By & Through The State Board Of Higher Education On Behalf Of The University Of Oregon Methods of mapping polymorphisms and polymorphism microarrays
US8445194B2 (en) 2005-06-15 2013-05-21 Callida Genomics, Inc. Single molecule arrays for genetic and chemical analysis
US20090264299A1 (en) * 2006-02-24 2009-10-22 Complete Genomics, Inc. High throughput genome sequencing on DNA arrays
EP2302070B1 (en) 2005-06-23 2012-08-22 Keygene N.V. Strategies for high throughput identification and detection of polymorphisms
CA2613248A1 (en) * 2005-06-23 2006-12-28 Keygene N.V. Improved strategies for sequencing complex genomes using high throughput sequencing technologies
GB0514935D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Methods for sequencing a polynucleotide template
GB0514910D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Method for sequencing a polynucleotide template
EP1924705A1 (en) * 2005-08-02 2008-05-28 Rubicon Genomics, Inc. Isolation of cpg islands by thermal segregation and enzymatic selection-amplification method
DK1924704T3 (en) 2005-08-02 2011-09-05 Rubicon Genomics Inc Compositions and Methods for Processing and Multiplying DNA, including Using Multiple Enzymes in a Single Reaction
US7622121B2 (en) 2005-09-21 2009-11-24 New York University Heat shock proteins from Mycobacterium leprae and uses thereof
US10316364B2 (en) 2005-09-29 2019-06-11 Keygene N.V. Method for identifying the source of an amplicon
EP1929039B2 (en) 2005-09-29 2013-11-20 Keygene N.V. High throughput screening of mutagenized populations
EP2546360A1 (en) 2005-10-07 2013-01-16 Callida Genomics, Inc. Self-assembled single molecule arrays and uses thereof
US7960104B2 (en) * 2005-10-07 2011-06-14 Callida Genomics, Inc. Self-assembled single molecule arrays and uses thereof
GB0522310D0 (en) 2005-11-01 2005-12-07 Solexa Ltd Methods of preparing libraries of template polynucleotides
RU2008123384A (en) 2005-11-16 2009-12-27 Новартис АГ (CH) BIOMARKERS FOR ANTIBODY TREATMENT for Nogo-A IN SPINAL DAMAGE
GB0524069D0 (en) * 2005-11-25 2006-01-04 Solexa Ltd Preparation of templates for solid phase amplification
US8137936B2 (en) * 2005-11-29 2012-03-20 Macevicz Stephen C Selected amplification of polynucleotides
US11306351B2 (en) 2005-12-21 2022-04-19 Affymetrix, Inc. Methods for genotyping
EP2789696B1 (en) 2005-12-22 2015-12-16 Keygene N.V. Method for high-throughput AFLP-based polymorphism detection
US8222482B2 (en) 2006-01-26 2012-07-17 Ceres, Inc. Modulating plant oil levels
DK1987159T4 (en) 2006-02-08 2020-11-16 Illumina Cambridge Ltd PROCEDURE FOR SEQUENCE OF A POLYNUCLEOTID TEMPLATE
EP1994180A4 (en) 2006-02-24 2009-11-25 Callida Genomics Inc High throughput genome sequencing on dna arrays
ES2301342B1 (en) * 2006-03-14 2009-05-01 Oryzon Genomics, S.A. "METHOD OF ANALYSIS OF NUCLEIC ACIDS".
EP2021503A1 (en) * 2006-03-17 2009-02-11 Solexa Ltd. Isothermal methods for creating clonal single molecule arrays
DK2002017T3 (en) 2006-04-04 2015-09-07 Keygene Nv High-capacity detection of molecular markers based on restriction fragments
US20130191941A1 (en) 2006-07-05 2013-07-25 Shing Kwok Modulating light response pathways in plants, increasing light-related tolerances in plants, and increasing biomass in plants
EP2038425B1 (en) 2006-07-12 2010-09-15 Keygene N.V. High throughput physical mapping using aflp
EP2049682A2 (en) * 2006-07-31 2009-04-22 Illumina Cambridge Limited Method of library preparation avoiding the formation of adaptor dimers
US7754429B2 (en) 2006-10-06 2010-07-13 Illumina Cambridge Limited Method for pair-wise sequencing a plurity of target polynucleotides
EP2063701A2 (en) 2006-10-18 2009-06-03 Seminis Vegetable Seeds, Inc. Carrots having increased lycopene content
WO2008070352A2 (en) * 2006-10-27 2008-06-12 Complete Genomics, Inc. Efficient arrays of amplified polynucleotides
US20090111705A1 (en) * 2006-11-09 2009-04-30 Complete Genomics, Inc. Selection of dna adaptor orientation by hybrid capture
US20090105961A1 (en) * 2006-11-09 2009-04-23 Complete Genomics, Inc. Methods of nucleic acid identification in large-scale sequencing
WO2008093098A2 (en) 2007-02-02 2008-08-07 Illumina Cambridge Limited Methods for indexing samples and sequencing multiple nucleotide templates
US20100120036A1 (en) * 2007-03-07 2010-05-13 Kunio Shiota Method for amplifying dna fragment
US20080293589A1 (en) * 2007-05-24 2008-11-27 Affymetrix, Inc. Multiplex locus specific amplification
AR066922A1 (en) 2007-06-08 2009-09-23 Monsanto Technology Llc METHODS OF MOLECULAR IMPROVEMENT OF THE GERMOPLASMA OF A PLANT BY DIRECTED SEQUENCING
WO2009007091A2 (en) 2007-07-09 2009-01-15 Bayer Bioscience N.V. Brassica plant comprising mutant fatty acyl-acp thioesterase alleles
US9388457B2 (en) 2007-09-14 2016-07-12 Affymetrix, Inc. Locus specific amplification using array probes
WO2009052214A2 (en) * 2007-10-15 2009-04-23 Complete Genomics, Inc. Sequence analysis using decorated nucleic acids
US8415099B2 (en) 2007-11-05 2013-04-09 Complete Genomics, Inc. Efficient base determination in sequencing reactions
US8518640B2 (en) * 2007-10-29 2013-08-27 Complete Genomics, Inc. Nucleic acid sequencing and process
US8298768B2 (en) * 2007-11-29 2012-10-30 Complete Genomics, Inc. Efficient shotgun sequencing methods
US8617811B2 (en) * 2008-01-28 2013-12-31 Complete Genomics, Inc. Methods and compositions for efficient base calling in sequencing reactions
US7901890B2 (en) * 2007-11-05 2011-03-08 Complete Genomics, Inc. Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation
US7897344B2 (en) * 2007-11-06 2011-03-01 Complete Genomics, Inc. Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs
MX2010004863A (en) 2007-11-02 2010-07-28 Ceres Inc Materials and methods for use in biomass processing.
NL2000992C2 (en) 2007-11-09 2009-05-12 Nunhems Bv New cucumber plants with compact growth.
EA031125B1 (en) 2007-11-28 2018-11-30 Байер Кропсайенс Н.В. Brassica plant comprising a mutant indehiscent allele
US8592150B2 (en) 2007-12-05 2013-11-26 Complete Genomics, Inc. Methods and compositions for long fragment read sequencing
WO2009094583A1 (en) * 2008-01-23 2009-07-30 Complete Genomics, Inc. Methods and compositions for preventing bias in amplification and sequencing reactions
BRPI0908140B1 (en) 2008-02-15 2023-05-16 Ceres, Inc METHODS FOR PRODUCING A PLANT, FOR MODULATING DRY AND HEAT TOLERANCE IN A PLANT, FOR OBTAINING A TRANSGENIC PLANT AND ISOLATED NUCLEIC ACID
WO2011025477A1 (en) 2009-08-25 2011-03-03 Illumina, Inc. Methods for selecting and amplifying polynucleotides
US12060554B2 (en) 2008-03-10 2024-08-13 Illumina, Inc. Method for selecting and amplifying polynucleotides
US9074244B2 (en) 2008-03-11 2015-07-07 Affymetrix, Inc. Array-based translocation and rearrangement assays
US20090270273A1 (en) * 2008-04-21 2009-10-29 Complete Genomics, Inc. Array structures for nucleic acid detection
MX2010012883A (en) 2008-05-26 2010-12-14 Bayer Bioscience Nv Methods and means to modify fiber strength in fiber-producing plants.
EP2304038B1 (en) 2008-07-17 2016-08-31 Bayer CropScience NV Brassica plant comprising a mutant indehiscent allelle
EP2172565A1 (en) * 2008-09-24 2010-04-07 Cyano Biotech GmbH Method of identifying and/or differentiating cyanophyta
JP2012510810A (en) * 2008-12-04 2012-05-17 キージーン・エン・フェー Method for reducing repetitive sequences in adapter-linked restriction fragments
CN102272334B (en) 2009-01-13 2014-08-20 关键基因股份有限公司 Novel genome sequencing strategies
WO2010105275A2 (en) 2009-03-13 2010-09-16 Cornell University Method to assess human allograft status from microrna expression levels
US8071864B2 (en) 2009-04-15 2011-12-06 Monsanto Technology Llc Plants and seeds of corn variety CV897903
US8362332B2 (en) 2009-04-15 2013-01-29 Monsanto Technology Llc Plants and seeds of corn variety CV165560
US8071865B2 (en) 2009-04-15 2011-12-06 Monsanto Technology Llc Plants and seeds of corn variety CV589782
EP2248914A1 (en) * 2009-05-05 2010-11-10 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. The use of class IIB restriction endonucleases in 2nd generation sequencing applications
US9524369B2 (en) 2009-06-15 2016-12-20 Complete Genomics, Inc. Processing and analysis of complex nucleic acid sequence data
CN102770018A (en) 2009-07-07 2012-11-07 安莎种子公司 Cucumber vein yellowing virus (CVYV) resistant cucumber plants (Cucumis sativus L.)
WO2011011412A2 (en) 2009-07-20 2011-01-27 Ceres, Inc. Transgenic plants having increased biomass
US20110059453A1 (en) * 2009-08-23 2011-03-10 Affymetrix, Inc. Poly(A) Tail Length Measurement by PCR
WO2011071382A1 (en) 2009-12-10 2011-06-16 Keygene N.V. Polymorfphic whole genome profiling
EP2333104A1 (en) 2009-12-11 2011-06-15 Lexogen GmbH RNA analytics method
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
CN102656279A (en) 2009-12-17 2012-09-05 凯津公司 Restriction enzyme based whole genome sequencing
EP2354243A1 (en) 2010-02-03 2011-08-10 Lexogen GmbH Complexity reduction method
US9746479B2 (en) 2010-03-09 2017-08-29 Cornell University Methods and compositions to predict and detect acute rejection
NL2004412C2 (en) 2010-03-16 2011-09-20 Nickerson Zwaan B V Male sterile leek plants.
US9313961B2 (en) 2010-04-20 2016-04-19 Seminis Vegetable Seeds, Inc. White-stem trait containing plants
US9441233B2 (en) 2010-05-06 2016-09-13 Ceres, Inc. Transgenic plants having increased biomass
EP2580351B1 (en) 2010-06-09 2018-08-29 Keygene N.V. Combinatorial sequence barcodes for high throughput screening
BR112013010278B1 (en) 2010-10-27 2020-12-29 Ceres, Inc method to produce a plant, method to modulate the biomass composition in a plant, isolated nucleic acid and method to alter the biomass composition in a plant
US8766054B2 (en) 2010-12-08 2014-07-01 Hm.Clause Phytophthora resistance in sweet peppers
WO2012084742A1 (en) 2010-12-24 2012-06-28 Bayer Cropscience Nv Brassica plant comprising a mutant alcatraz allele
KR20140040697A (en) 2011-01-14 2014-04-03 키진 엔.브이. Paired end random sequence based genotyping
TWI465572B (en) * 2011-05-19 2014-12-21 Univ Chang Gung Method, composition and system of amplification and detection of target microbial DNA
ES2556580T3 (en) 2011-07-08 2016-01-19 Keygene N.V. Genotyping based on sequences based on oligonucleotide ligation assays
EP2753715A4 (en) 2011-09-09 2015-05-20 Univ Leland Stanford Junior Methods for obtaining a sequence
US9938536B2 (en) 2011-11-02 2018-04-10 Ceres, Inc. Transgenic plants having increased tolerance to aluminum
US10323256B2 (en) 2011-12-09 2019-06-18 Ceres, Inc. Transgenic plants having altered biomass composition
EP2802666B1 (en) 2012-01-13 2018-09-19 Data2Bio Genotyping by next-generation sequencing
SI3363901T1 (en) * 2012-02-17 2021-04-30 Fred Hutchinson Cancer Research Center Compositions and methods for accurately identifying mutations
US11177020B2 (en) 2012-02-27 2021-11-16 The University Of North Carolina At Chapel Hill Methods and uses for molecular tags
US9873886B2 (en) 2012-07-06 2018-01-23 Bayer Cropscience Nv Brassica ROD1 gene sequences and uses thereof
AU2013285460A1 (en) 2012-07-06 2015-01-22 Bayer Cropscience Nv Brassica plants with modified seed oil composition
CA2878287A1 (en) 2012-07-06 2014-01-09 Bayer Cropscience Nv Soybean rod1 gene sequences and uses thereof
EP2728013A1 (en) * 2012-10-31 2014-05-07 Universitätsspital Basel Method for the simultaneous amplification of a plurality of different nucleic acid target sequences
US9758828B2 (en) 2013-01-31 2017-09-12 Cornell University Methods to detect, treat and prevent acute cellular rejection in kidney allografts
HUE044202T2 (en) 2013-04-19 2019-10-28 BASF Agricultural Solutions Seed US LLC Hybrid brassica plants and methods for producing same
RU2549453C2 (en) * 2013-04-26 2015-04-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" SET OF SYNTHETIC OLIGONUCLEOTIDES FOR IDENTIFICATION OF SPECIES AFFILIATION OF COMMON HEATHER (Calluna vulgaris (L.) Hull.)
CN103233072B (en) * 2013-05-06 2014-07-02 中国海洋大学 High-flux mythelation detection technology for DNA (deoxyribonucleic acid) of complete genome
RU2535064C1 (en) * 2013-05-30 2014-12-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" SET OF SYNTHETIC OLIGONUCLEOTIDES FOR SPECIES IDENTIFICATION OF SPINY ELEUTEROCOCUS, ELEUTHEROCOCCUS (Eleutherococcus senticocus (Rupr. et Maxim.) Maxim.)
RU2535063C1 (en) * 2013-05-30 2014-12-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" KIT OF SYNTHETIC OLIGONUCLEOTIDES FOR IDENTIFYING SPECIES OF COTTON WEED (Filaginella uliginosa (L) Opiz)
RU2535060C1 (en) * 2013-05-30 2014-12-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" SET OF SYNTHETIC OLIGONUCLEOTIDES FOR SPECIES IDENTIFICATION OF JAPANESE ANGELICA TREE (Aralia elata (Miq.) Seem.)
US9982301B2 (en) 2014-01-07 2018-05-29 Cornell University Urine mRNA profile and acute dysfunction of kidney allograft
WO2015112767A2 (en) 2014-01-22 2015-07-30 Life Technologies Corporation Novel reverse transcriptases for use in high temperature nucleic acid synthesis
US20140245471A1 (en) 2014-05-02 2014-08-28 Nunhems B.V. Carrot plants with a high anthocyanin level
US9107356B2 (en) 2014-05-02 2015-08-18 Nunhems B.V. Hybrid carrot variety NUN 85931
US10480000B2 (en) 2014-07-15 2019-11-19 Ceres, Inc. Methods of increasing crop yield under abiotic stress
RU2573937C1 (en) * 2014-10-20 2016-01-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Алтайский государственный университет" SET OF SYNTHETIC OLIGONUCLEOTIDES FOR SPECIES IDENTIFICATION OF BUPLEURUM MULTINERVE (Bupleurum multinerve DC)
KR102534706B1 (en) 2014-10-30 2023-05-23 넌헴스 비.브이. Lettuce plants comprising resistance against nasonovia ribisnigri biotype 1
CA2983893A1 (en) 2015-04-28 2016-11-03 Bayer Cropscience Nv Brassica plants with modified seed oil composition
EP3344774A1 (en) 2015-09-04 2018-07-11 Keygene N.V. Diplospory gene
US10226015B2 (en) 2015-11-10 2019-03-12 Pop Vriend Research B.V. Peronospora resistance in Spinacia sp
US11277983B2 (en) 2015-11-10 2022-03-22 Pop Vriend Seeds Bv Peronospora resistance in spinacia sp
WO2018091438A1 (en) 2016-11-17 2018-05-24 Nunhems B.V. Multibranching artichoke plant
US11584958B2 (en) 2017-03-31 2023-02-21 Grail, Llc Library preparation and use thereof for sequencing based error correction and/or variant identification
WO2019068647A1 (en) 2017-10-04 2019-04-11 Hild Samen Gmbh Complete resistance to downy mildew in basil
CA3086620A1 (en) 2018-01-12 2019-07-18 Basf Se Gene underlying the number of spikelets per spike qtl in wheat on chromosome 7a
ES2968531T3 (en) 2018-01-26 2024-05-10 Nunhems Bv Spinach plants resistant to at least races 8, 9, 11, 13 and 16 of Peronospora farinosa
JP7530355B2 (en) 2018-11-28 2024-08-07 キージーン ナムローゼ フェンノートシャップ Targeted enrichment by endonuclease protection
KR20210100689A (en) 2018-12-13 2021-08-17 넌헴스 비.브이. Solanaceae plants capable of forming gastric unit fruit
AU2020225760A1 (en) 2019-02-21 2021-08-19 Keygene N.V. Genotyping of polyploids
WO2020239984A1 (en) 2019-05-29 2020-12-03 Keygene N.V. Gene for parthenogenesis
US12054726B2 (en) 2019-06-13 2024-08-06 Nunhems B.V. Tomato plant producing fruit having improved ripening characteristics
JP2023504022A (en) 2019-11-26 2023-02-01 ヌンヘムス、ベスローテン、フェンノートシャップ Molecular markers for the reduced pyruvate level trait in onions
JP2023505712A (en) 2019-12-12 2023-02-10 キージーン ナムローゼ フェンノートシャップ Nucleic acid manipulation in semi-solid state
CA3161280A1 (en) 2019-12-20 2021-06-24 Rene Cornelis Josephus Hogers Next-generation sequencing library preparation using covalently closed nucleic acid molecule ends
US20240292805A1 (en) 2020-04-23 2024-09-05 Nunhems B.V. Solanum lycopersicum plants having improved tobamovirus resistance
MX2022014185A (en) 2020-05-13 2022-12-07 Nunhems Bv Tomato plants having suppressed meiotic recombination.
US20230232762A1 (en) 2020-06-10 2023-07-27 Nunhems B.V. Capsicum annuum plants having improved thrips resistance
WO2022074058A1 (en) 2020-10-06 2022-04-14 Keygene N.V. Targeted sequence addition
IL301700A (en) 2020-10-13 2023-05-01 Keygene Nv Modified promoter of a parthenogenesis gene
US20240002904A1 (en) 2020-11-24 2024-01-04 Keygene N.V. Targeted enrichment using nanopore selective sequencing
US20240292798A1 (en) 2020-12-21 2024-09-05 BASF Agricultural Solutions Seed US LLC Brassica napus plants comprising an improved fertility restorer
US20240076653A1 (en) * 2020-12-31 2024-03-07 Mokobio Life Science Corporation Beijing Method for constructing multiplex pcr library for high-throughput targeted sequencing
WO2022265965A1 (en) 2021-06-14 2022-12-22 10X Genomics, Inc. Reverse transcriptase variants for improved performance
CN117794357A (en) 2021-07-23 2024-03-29 巴斯夫农业种子解决方案美国有限责任公司 Black shank-resistant plants and methods for identifying black shank-resistant plants
US12004476B2 (en) 2022-01-26 2024-06-11 Monsanto Technology Llc. Cotton variety 20R750B3XF
WO2024121354A1 (en) 2022-12-08 2024-06-13 Keygene N.V. Duplex sequencing with covalently closed dna ends
WO2024146898A1 (en) 2023-01-03 2024-07-11 Keygene N.V. Nal1 in rice

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4321365A (en) * 1977-10-19 1982-03-23 Research Corporation Oligonucleotides useful as adaptors in DNA cloning, adapted DNA molecules, and methods of preparing adaptors and adapted molecules
US5093245A (en) * 1988-01-26 1992-03-03 Applied Biosystems Labeling by simultaneous ligation and restriction
EP0456721A4 (en) * 1989-01-31 1992-06-03 University Of Miami Microdissection and amplification of chromosomal dna
WO1990012115A1 (en) * 1989-03-21 1990-10-18 Collaborative Research, Inc. A dna diagnostic test using an exonuclease activity
JPH05508305A (en) * 1989-10-16 1993-11-25 ジエネラブス・テクノロジーズ・インコーポレイテツド Non-specific DNA amplification
WO1991014003A2 (en) * 1990-03-09 1991-09-19 Ig Laboratories, Inc. Characterization and analysis of polymorphic vntr loci
US5126239A (en) * 1990-03-14 1992-06-30 E. I. Du Pont De Nemours And Company Process for detecting polymorphisms on the basis of nucleotide differences
WO1992007095A1 (en) * 1990-10-15 1992-04-30 Stratagene Arbitrarily primed polymerase chain reaction method for fingerprinting genomes
WO1992013104A1 (en) * 1991-01-22 1992-08-06 Board Of Regents, The University Of Texas System 5' and 3' polymerase chain reaction walking from known dna sequences

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7956239B2 (en) 2001-06-07 2011-06-07 Pioneer Hi-Bred International, Inc. QTL controlling Sclerotinia stem ROT resistance in soybean
US7968763B2 (en) 2001-06-07 2011-06-28 Pioneer Hi-BredInternational, Inc. QTL controlling sclerotinia stem ROT resistance in soybean

Also Published As

Publication number Publication date
EP0534858A1 (en) 1993-03-31
KR100321510B1 (en) 2005-01-10
DK0534858T4 (en) 2005-08-08
RU94033149A (en) 1996-07-27
PT534858E (en) 2000-09-29
NO941064L (en) 1994-05-20
DE69230873T3 (en) 2006-04-06
JP2001061486A (en) 2001-03-13
FI20031526A (en) 2003-10-17
NO318016B1 (en) 2005-01-24
EP0969102A2 (en) 2000-01-05
IL103267A (en) 2004-07-25
ES2147550T3 (en) 2000-09-16
HUT68504A (en) 1995-06-28
EP0534858B1 (en) 2000-04-05
HU9400809D0 (en) 1994-06-28
FI115402B (en) 2005-04-29
JP4385072B2 (en) 2009-12-16
DE69230873D1 (en) 2000-05-11
FI941360A (en) 1994-05-24
CZ291877B6 (en) 2003-06-18
IL103267A0 (en) 1993-02-21
GR3033895T3 (en) 2000-11-30
JP2008131947A (en) 2008-06-12
FI113184B (en) 2004-03-15
DK0534858T3 (en) 2000-09-11
DE69230873T2 (en) 2000-11-09
DE69233719T2 (en) 2009-01-02
CZ66994A3 (en) 1994-12-15
ATE191510T1 (en) 2000-04-15
RU2182176C2 (en) 2002-05-10
CZ298187B6 (en) 2007-07-18
JP3236295B2 (en) 2001-12-10
PT969102E (en) 2008-03-25
ATE382094T1 (en) 2008-01-15
EP0969102B1 (en) 2007-12-26
HU223760B1 (en) 2005-01-28
EP0969102A3 (en) 2000-02-23
JP4088403B2 (en) 2008-05-21
US6045994A (en) 2000-04-04
DE69233719D1 (en) 2008-02-07
CA2119557C (en) 2004-02-24
ZA927323B (en) 1993-08-30
EP0534858B2 (en) 2005-04-27
JPH06510668A (en) 1994-12-01
AU2662992A (en) 1993-04-27
WO1993006239A1 (en) 1993-04-01
ES2147550T5 (en) 2005-11-01
FI941360A0 (en) 1994-03-24
DK0969102T3 (en) 2008-05-13
AU672760B2 (en) 1996-10-17
ES2299229T3 (en) 2008-05-16
NO941064D0 (en) 1994-03-23

Similar Documents

Publication Publication Date Title
CA2119557A1 (en) Selective restriction fragment amplification: a general method for dna fingerprinting
DE69331665D1 (en) METHOD FOR TREATING NUCLEIC ACID SAMPLES
DE69636080D1 (en) A cascading amplification reaction of nucleic acids
NO873753D0 (en) PERIODIC BIOLOGICAL AIR TREATMENT PROCESS AND SYSTEM FOR THIS.
IT8819722A0 (en) IMPROVED METHOD FOR THE ANALYSIS OF NUCLEIC ACIDS, A COMBINATION OF REAGENTS AND A KIT TO PERFORM IT.
DE69029105D1 (en) Rapid method for the detection and / or identification of a single base in a nucleic acid sequence and its uses
DE69329636D1 (en) Process for the amplification of nucleic acid sequences
NO904634L (en) AMPLIFICATION OF NUCLEIC ACID USING LIGARABLE, HAARNAAL PROBLEMS AND TRANSCRIPTION.
PT84207B (en) PROCESS FOR THE EXPRESSION OF GENES IN PLANTS, DNA FRAGMENTS, PLASMIDES AND PROCESSED MICROORGANISMS
ATE412002T1 (en) NUCLEIC ACID CAPTIVITY GROUPS
FI940203A (en) Gene encoding enzymes synthesizing eicosaptic acid and method for producing eicospentanoic acid
DE59712415D1 (en) PROCESS FOR THE AMPLIFICATION OF NUCLEIC ACID
DE3582541D1 (en) ANTI-ABC OVERSHOE (ATOMAR, ORGANIC OR BACTERIAL, CHEMICAL) AND ITS PRODUCTION PROCESS.
AU5409596A (en) A method of improving the chemical, physical and biological processes in agriculture, horticulture and animal husbandry and in humans
EP0645460A3 (en)
NO892990D0 (en) METHODS AND METHOD OF INCREASING NUCLEIC ACID HYBRIDIZATION.
FR2729970B1 (en) DNA FRAGMENT, VECTOR, CORYNEFORMED BACTERIA AND PROCESS FOR PRODUCING L-AMINO ACIDS OR NUCLEIC ACIDS USING THEM
DE59005296D1 (en) METHOD FOR Raising and / or Fattening Pigs, and Feed Mixture.
ATE108834T1 (en) SPECIFIC NUCLEIC ACID FRAGMENTS OF HUMAN VILLINGENS, THEIR APPLICATION FOR DIAGNOSTIC PURPOSES.
FI940830A (en) Method for the identification of rapidly hybridizing, single-stranded polynucleotides
AU4185889A (en) Nucleic acid amplification process
SE9403169D0 (en) Process for controlled manipulation of nucleic acid fragments
NO875058L (en) OLIGONUCLEOTIDE PROBLEMS AND PROCEDURE FOR DETECTING THE NUCLEIC ACIDS IN BACTERIA AND OTHER LIVING ORGANISMS BY HYBRIDIZATION.
SE9403170D0 (en) Process for nucleic acid hybridization analysis
FR2734279B1 (en) BARLEY MALT PROCESS AND IMPROVED MALT THUS OBTAINED

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry