AU2001271720A1 - Methods and compositions for determining gene function - Google Patents

Methods and compositions for determining gene function

Info

Publication number
AU2001271720A1
AU2001271720A1 AU2001271720A AU7172001A AU2001271720A1 AU 2001271720 A1 AU2001271720 A1 AU 2001271720A1 AU 2001271720 A AU2001271720 A AU 2001271720A AU 7172001 A AU7172001 A AU 7172001A AU 2001271720 A1 AU2001271720 A1 AU 2001271720A1
Authority
AU
Australia
Prior art keywords
compositions
methods
gene function
determining gene
determining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001271720A
Inventor
Timothy R. Hughes
Roland Stoughton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rosetta Inpharmatics LLC
Original Assignee
Rosetta Inpharmatics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rosetta Inpharmatics LLC filed Critical Rosetta Inpharmatics LLC
Publication of AU2001271720A1 publication Critical patent/AU2001271720A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/50—Mutagenesis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30—Unsupervised data analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
AU2001271720A 2000-07-05 2001-07-02 Methods and compositions for determining gene function Abandoned AU2001271720A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21593600P 2000-07-05 2000-07-05
US60/215,936 2000-07-05
PCT/US2001/020928 WO2002002740A2 (en) 2000-07-05 2001-07-02 Methods and compositions for determining gene function

Publications (1)

Publication Number Publication Date
AU2001271720A1 true AU2001271720A1 (en) 2002-01-14

Family

ID=22805001

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001271720A Abandoned AU2001271720A1 (en) 2000-07-05 2001-07-02 Methods and compositions for determining gene function

Country Status (3)

Country Link
US (2) US7657379B2 (en)
AU (1) AU2001271720A1 (en)
WO (1) WO2002002740A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002002740A2 (en) 2000-07-05 2002-01-10 Rosetta Inpharmatics, Inc. Methods and compositions for determining gene function
JP4002754B2 (en) * 2000-12-12 2007-11-07 独立行政法人科学技術振興機構 Gene function analysis database and gene function analysis method using DSPA
US9053222B2 (en) 2002-05-17 2015-06-09 Lawrence A. Lynn Patient safety processor
US20090281838A1 (en) 2008-05-07 2009-11-12 Lawrence A. Lynn Medical failure pattern search engine
US20030108890A1 (en) * 2001-05-30 2003-06-12 Baranova Anna Vjacheslavovna In silico screening for phenotype-associated expressed sequences
US7224825B2 (en) * 2002-04-18 2007-05-29 Lockheed Martin Corporation Detecting and identifying hazardous substances contained in mail articles
US7282328B2 (en) 2002-09-20 2007-10-16 New England Biolabs, Inc. Helicase dependent amplification of nucleic acids
US7662594B2 (en) 2002-09-20 2010-02-16 New England Biolabs, Inc. Helicase-dependent amplification of RNA
FI119160B (en) * 2005-10-10 2008-08-15 Medicel Oy Database Management System
US20140241601A1 (en) 2013-02-28 2014-08-28 Lawrence A. Lynn System for Analysis and Imaging Using Perturbation Feature Quanta
US11728041B2 (en) 2008-05-07 2023-08-15 Lawrence A. Lynn Real-time time series matrix pathophysiologic pattern processor and quality assessment method
US20130097704A1 (en) * 2011-10-13 2013-04-18 Bitdefender IPR Management Ltd. Handling Noise in Training Data for Malware Detection
US9336302B1 (en) 2012-07-20 2016-05-10 Zuci Realty Llc Insight and algorithmic clustering for automated synthesis
US20140180722A1 (en) * 2012-11-14 2014-06-26 Lawrence A. Lynn Time Lapsable Motion Image Responsive to Features of Pathophysiologic Perturbations
US10354429B2 (en) 2012-11-14 2019-07-16 Lawrence A. Lynn Patient storm tracker and visualization processor
US9953453B2 (en) * 2012-11-14 2018-04-24 Lawrence A. Lynn System for converting biologic particle density data into dynamic images
US9074248B1 (en) 2012-12-18 2015-07-07 Qiagen Gmbh Primers for helicase dependent amplification and their methods of use
US10191929B2 (en) 2013-05-29 2019-01-29 Noblis, Inc. Systems and methods for SNP analysis and genome sequencing
US10546019B2 (en) 2015-03-23 2020-01-28 International Business Machines Corporation Simplified visualization and relevancy assessment of biological pathways
US10560552B2 (en) 2015-05-21 2020-02-11 Noblis, Inc. Compression and transmission of genomic information
US10803074B2 (en) * 2015-08-10 2020-10-13 Hewlett Packard Entperprise Development LP Evaluating system behaviour
US11205103B2 (en) 2016-12-09 2021-12-21 The Research Foundation for the State University Semisupervised autoencoder for sentiment analysis
US11222712B2 (en) 2017-05-12 2022-01-11 Noblis, Inc. Primer design using indexed genomic information
US11309058B2 (en) * 2018-03-30 2022-04-19 X Development Llc Modeling the chemical composition of a biological cell wall
US11715551B2 (en) 2019-06-19 2023-08-01 Recursion Pharmaceuticals, Inc. Systems and methods for evaluating query perturbations

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5116742A (en) 1986-12-03 1992-05-26 University Patents, Inc. RNA ribozyme restriction endoribonucleases and methods
US4904582A (en) 1987-06-11 1990-02-27 Synthetic Genetics Novel amphiphilic nucleic acid conjugates
US5300425A (en) * 1987-10-13 1994-04-05 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
WO1989012690A1 (en) 1988-06-13 1989-12-28 American Biogentic Sciences, Inc. Method for the production of monoclonal antibodies utilizing a germfree animal
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
WO1993006239A1 (en) 1991-09-24 1993-04-01 Keygene N.V. Selective restriction fragment amplification: a general method for dna fingerprinting
US5578832A (en) 1994-09-02 1996-11-26 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
US5539083A (en) 1994-02-23 1996-07-23 Isis Pharmaceuticals, Inc. Peptide nucleic acid combinatorial libraries and improved methods of synthesis
AU1837495A (en) 1994-10-13 1996-05-06 Horus Therapeutics, Inc. Computer assisted methods for diagnosing diseases
US5556752A (en) 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
US5569588A (en) 1995-08-09 1996-10-29 The Regents Of The University Of California Methods for drug screening
US6165709A (en) 1997-02-28 2000-12-26 Fred Hutchinson Cancer Research Center Methods for drug target screening
US6028189A (en) 1997-03-20 2000-02-22 University Of Washington Solvent for oligonucleotide synthesis and methods of use
AU751956B2 (en) 1997-03-20 2002-09-05 University Of Washington Solvent for biopolymer synthesis, solvent microdroplets and methods of use
US5965352A (en) 1998-05-08 1999-10-12 Rosetta Inpharmatics, Inc. Methods for identifying pathways of drug action
US6324479B1 (en) 1998-05-08 2001-11-27 Rosetta Impharmatics, Inc. Methods of determining protein activity levels using gene expression profiles
US6132969A (en) 1998-06-19 2000-10-17 Rosetta Inpharmatics, Inc. Methods for testing biological network models
EP1131483B1 (en) 1998-10-22 2003-11-05 Ciba SC Holding AG Inhibition of pulp and paper yellowing using hydroxylamines and other coadditives
US6203987B1 (en) 1998-10-27 2001-03-20 Rosetta Inpharmatics, Inc. Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns
US6468476B1 (en) 1998-10-27 2002-10-22 Rosetta Inpharmatics, Inc. Methods for using-co-regulated genesets to enhance detection and classification of gene expression patterns
US6950752B1 (en) 1998-10-27 2005-09-27 Rosetta Inpharmatics Llc Methods for removing artifact from biological profiles
US6263287B1 (en) * 1998-11-12 2001-07-17 Scios Inc. Systems for the analysis of gene expression data
US6801859B1 (en) 1998-12-23 2004-10-05 Rosetta Inpharmatics Llc Methods of characterizing drug activities using consensus profiles
US6271002B1 (en) 1999-10-04 2001-08-07 Rosetta Inpharmatics, Inc. RNA amplification method
WO2002002740A2 (en) 2000-07-05 2002-01-10 Rosetta Inpharmatics, Inc. Methods and compositions for determining gene function

Also Published As

Publication number Publication date
US20110251081A1 (en) 2011-10-13
WO2002002740A2 (en) 2002-01-10
US8412460B2 (en) 2013-04-02
US20040048264A1 (en) 2004-03-11
US7657379B2 (en) 2010-02-02
WO2002002740A3 (en) 2002-08-15

Similar Documents

Publication Publication Date Title
AU2001271720A1 (en) Methods and compositions for determining gene function
AU2001280968A1 (en) Compositions and methods for directed gene assembly
AU2778801A (en) Antisense compositions and methods
AU2625501A (en) Compositions and methods for gene silencing
AU2002357119A1 (en) Mitocidal compositions and methods
AU2001261566A1 (en) Well service composition and method
AU2001253255A1 (en) Compositions and methods for inhibiting gene expression
AU2001258771A1 (en) -secretase inhibitors
AU2001245987A1 (en) Compositions and methods for gene therapy
AU5781800A (en) Methods and compositions for assaying analytes
AU2001249444A1 (en) Methods and compositions for the simultaneous detection of multiple analytes
AU2001241098A1 (en) Composition
AU2001238485A1 (en) Methods and compositions for gene delivery
AU2002357748A1 (en) Osteopontin-related compositions and methods
AU2001266169A1 (en) Predicting changes in characteristics of an object
AU2001233932A1 (en) Method and composition
AU6094200A (en) Nor gene compositions and methods for use thereof
AU2001264247A1 (en) GASC1 gene
AU2002311759A1 (en) Methods and compositions for analyzing nucleic acids
AU2001278951A1 (en) Compounds and methods
AU2001275201A1 (en) Acne-treating composition
AUPQ749100A0 (en) New epilespy gene
AU2001247444A1 (en) Erbeta-mediated gene expression
AU2001285743A1 (en) Adipose-related gene
AU2001283226A1 (en) Methods and compositions for inhibiting rad51