DK0759773T3 - Tårekirtelspecifikke emulsioner til topisk påføring på okulært væv - Google Patents

Tårekirtelspecifikke emulsioner til topisk påføring på okulært væv

Info

Publication number
DK0759773T3
DK0759773T3 DK95921294T DK95921294T DK0759773T3 DK 0759773 T3 DK0759773 T3 DK 0759773T3 DK 95921294 T DK95921294 T DK 95921294T DK 95921294 T DK95921294 T DK 95921294T DK 0759773 T3 DK0759773 T3 DK 0759773T3
Authority
DK
Denmark
Prior art keywords
tear
topical application
ocular tissue
specific emulsions
fatty acid
Prior art date
Application number
DK95921294T
Other languages
Danish (da)
English (en)
Inventor
Walter L Tien
Orest Olejnik
Shulin Ding
Original Assignee
Allergan Sales Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22918100&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0759773(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Sales Inc filed Critical Allergan Sales Inc
Application granted granted Critical
Publication of DK0759773T3 publication Critical patent/DK0759773T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK95921294T 1994-05-17 1995-05-17 Tårekirtelspecifikke emulsioner til topisk påføring på okulært væv DK0759773T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/243,279 US5474979A (en) 1994-05-17 1994-05-17 Nonirritating emulsions for sensitive tissue
PCT/US1995/006302 WO1995031211A1 (en) 1994-05-17 1995-05-17 Lacrimal gland specific emulsions for topical application to ocular tissue

Publications (1)

Publication Number Publication Date
DK0759773T3 true DK0759773T3 (da) 2001-11-26

Family

ID=22918100

Family Applications (2)

Application Number Title Priority Date Filing Date
DK00202069T DK1044678T3 (da) 1994-05-17 1995-05-17 Tårekirtelspecifikke emulsioner til topisk anvendelse til okulært væv
DK95921294T DK0759773T3 (da) 1994-05-17 1995-05-17 Tårekirtelspecifikke emulsioner til topisk påføring på okulært væv

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK00202069T DK1044678T3 (da) 1994-05-17 1995-05-17 Tårekirtelspecifikke emulsioner til topisk anvendelse til okulært væv

Country Status (17)

Country Link
US (1) US5474979A (ko)
EP (2) EP1044678B1 (ko)
JP (2) JP3441462B2 (ko)
KR (2) KR100368181B1 (ko)
CN (2) CN1229136C (ko)
AT (2) ATE234076T1 (ko)
AU (1) AU693213B2 (ko)
BR (1) BR9507664A (ko)
CA (1) CA2190485C (ko)
DE (2) DE69529932T2 (ko)
DK (2) DK1044678T3 (ko)
ES (2) ES2161895T3 (ko)
GR (1) GR3036945T3 (ko)
HK (1) HK1034190A1 (ko)
NZ (1) NZ287635A (ko)
PT (2) PT1044678E (ko)
WO (1) WO1995031211A1 (ko)

Families Citing this family (122)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5585104A (en) * 1995-04-12 1996-12-17 The Procter & Gamble Company Cleansing emulsions
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
US5858401A (en) 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
JPH10218760A (ja) * 1997-02-04 1998-08-18 Nobel Igaku Kenkyusho:Kk ドライアイ治療用の微量油添加目薬
US5981607A (en) * 1998-01-20 1999-11-09 Allergan Emulsion eye drop for alleviation of dry eye related symptoms in dry eye patients and/or contact lens wearers
US6217895B1 (en) * 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
AUPQ228199A0 (en) * 1999-08-18 1999-09-09 Sly, Anthony William Ophthalmic fluid
EP1220849B1 (en) * 1999-10-15 2004-05-19 Sucampo AG Bicyclic compounds composition and method for stabilizing the same
US7270767B1 (en) 1999-10-18 2007-09-18 Foster-Miller, Inc. Environmentally friendly de-icer and anti-icer compositions
TR200302105T4 (tr) * 2000-04-07 2004-02-23 Laboratoire Medidom S. A. Siklosporin, hiyalüronik asit ve polisorbat içeren göz formülasyonları.
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
JP2004503593A (ja) 2000-07-14 2004-02-05 アラーガン、インコーポレイテッド 増大した溶解度を持つ治療活性成分を含む組成物
AU2002308760B2 (en) 2001-05-21 2006-05-11 Alcon, Inc. Use of proteasome inhibitors to treat dry eye disorders
US7112588B2 (en) 2001-05-21 2006-09-26 Alcon, Inc. Use of proteasome inhibitors to treat dry eye disorders
DE60213230T2 (de) 2001-05-21 2006-11-23 Alcon Inc. Verwendung von NF-Kappa.B Inhibitoren zur Behandlung von Augentrockenheit
US6872382B1 (en) 2001-05-21 2005-03-29 Alcon, Inc. Use of selective PDE IV inhibitors to treat dry eye disorders
US6645994B1 (en) 2001-06-01 2003-11-11 Alcon, Inc. Method of treating dry eye disorders
US6872705B2 (en) * 2001-07-13 2005-03-29 Allergan, Inc. Use of antimicrobial peptides as preservatives in ophthalmic preparations, including solutions, emulsions, and suspensions
AU2002333098B2 (en) * 2001-10-19 2006-03-16 Isotechnika Pharma Inc. Novel cyclosporin analog microemulsion preconcentrates
US6656460B2 (en) 2001-11-01 2003-12-02 Yissum Research Development Method and composition for dry eye treatment
US7351404B2 (en) 2002-02-04 2008-04-01 Allergan, Inc. Method of enhancing hair growth
US9216183B2 (en) 2002-02-04 2015-12-22 Allergan, Inc. Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide F2 alpha agonists
US8758733B2 (en) 2002-02-04 2014-06-24 Allergan, Inc. Topical treatment for chemotherapy induced eyelash loss or hypotrichosis using prostamide F2 alpha agonists
US6982079B2 (en) * 2002-04-26 2006-01-03 Allergan, Inc. Compositions for treating hyperemia
US8871241B2 (en) 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
US6635654B1 (en) 2003-01-09 2003-10-21 Allergan, Inc. Ophthalmic compositions containing loratadine
US6984628B2 (en) 2003-07-15 2006-01-10 Allergan, Inc. Ophthalmic compositions comprising trefoil factor family peptides
US20050059583A1 (en) * 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
RU2007103835A (ru) 2004-07-01 2008-08-10 Шепенс Ай Рисерч (Us) Композиции и способы лечения заболеваний и нарушений состояния глаз
JP4586068B2 (ja) * 2004-07-01 2010-11-24 イーエルシー マネージメント エルエルシー 化粧品組成物および感覚的冷却方法
US7135455B2 (en) * 2004-11-15 2006-11-14 Allergan, Inc Methods for the therapeutic use of cyclosporine components
US7151085B2 (en) 2004-11-15 2006-12-19 Allergan, Inc. Therapeutic methods using cyclosporine components
US7851504B2 (en) * 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
US9241918B2 (en) 2005-03-16 2016-01-26 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
CN100478025C (zh) * 2005-03-25 2009-04-15 中国科学院上海药物研究所 一种环孢菌素a眼用微乳制剂及其制备方法
CN100562340C (zh) * 2005-06-17 2009-11-25 中国科学院上海药物研究所 一种微乳型人工泪液
CN1319515C (zh) * 2005-07-12 2007-06-06 沈阳何氏生物工程有限公司 活肤眼霜
US8288348B2 (en) * 2005-07-13 2012-10-16 Allergan, Inc. Cyclosporin compositions
US7276476B2 (en) 2005-07-13 2007-10-02 Allergan, Inc. Cyclosporin compositions
US7297679B2 (en) * 2005-07-13 2007-11-20 Allergan, Inc. Cyclosporin compositions
US20070015691A1 (en) * 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US20070015693A1 (en) * 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US7288520B2 (en) * 2005-07-13 2007-10-30 Allergan, Inc. Cyclosporin compositions
US7202209B2 (en) * 2005-07-13 2007-04-10 Allergan, Inc. Cyclosporin compositions
US7501393B2 (en) * 2005-07-27 2009-03-10 Allergan, Inc. Pharmaceutical compositions comprising cyclosporins
US9839667B2 (en) 2005-10-14 2017-12-12 Allergan, Inc. Prevention and treatment of ocular side effects with a cyclosporin
US7745400B2 (en) * 2005-10-14 2010-06-29 Gregg Feinerman Prevention and treatment of ocular side effects with a cyclosporin
CN101355876B (zh) * 2005-11-09 2012-09-05 康宾纳特克斯公司 一种适用于眼部给药的组合物
US11311477B2 (en) 2006-03-07 2022-04-26 Sgn Nanopharma Inc. Ophthalmic preparations
US10137083B2 (en) * 2006-03-07 2018-11-27 SGN Nanopharma Inc Ophthalmic preparations
US9561178B2 (en) * 2006-07-25 2017-02-07 Allergan, Inc. Cyclosporin compositions
US10265265B2 (en) 2007-03-15 2019-04-23 Drug Delivery Solutions Limited Topical composition
WO2008137617A1 (en) * 2007-05-04 2008-11-13 Allergan, Inc. Use of cyclosporines in the treatment of patients with intraocular lenses
FR2916636B1 (fr) * 2007-05-29 2009-09-04 Octalia Technologies Vehicule sous forme d'une emulsion huile-dans-eau notamment destine a une utilisation ophtalmique ou dermocosmetique
EP2008651A1 (en) 2007-06-26 2008-12-31 Drug Delivery Solutions Limited A bioerodible patch
EP2197461B1 (en) 2007-10-08 2018-02-21 Aurinia Pharmaceuticals Inc. Ophthalmic compositions comprising calcineurin inhibitors or mtor inhibitors
KR100985279B1 (ko) * 2008-03-05 2010-11-05 디렉스 팜 (주) 안구건조증 치료를 위한 안약조성물 및 그 제조방법
CA2730108A1 (en) * 2008-07-10 2010-01-14 Allergan, Inc. Cyclosporin derivatives for treating ocular and dermal diseases and conditions
US20100016219A1 (en) * 2008-07-19 2010-01-21 Jerry Zhang Ophthalmic compositions containing solubilized cyclosporin
FR2938757B1 (fr) * 2008-11-27 2010-12-31 Octalia Technologies Vehicule sous forme d'une emulsion huile-dans-eau notamment destine a une utilisation cosmetique ou dermatologique
US20100204335A1 (en) * 2008-12-01 2010-08-12 Allergan, Inc. Kit and composition for eyelash growth
CN102271700A (zh) * 2009-01-08 2011-12-07 阿勒根公司 用于促进甲生长的环孢菌素组合物
US20110009339A1 (en) 2009-04-14 2011-01-13 Allergan, Inc Method of treating blurred vision and other conditions of the eye with cyclosporin compositions
WO2010127301A1 (en) * 2009-05-01 2010-11-04 Allergan, Inc. Method of treating allergic conjunctivitis with cyclosporin compositions
AU2010256652B2 (en) 2009-06-05 2015-11-26 Allergan, Inc. Artificial tears and therapeutic uses
US9017725B2 (en) 2009-06-09 2015-04-28 Aurinia Pharmaceuticals Inc. Topical drug delivery systems for ophthalmic use
US9149484B2 (en) 2009-11-09 2015-10-06 Allergan, Inc. Compositions and methods for stimulating hair growth
KR20170095402A (ko) 2009-11-09 2017-08-22 알러간, 인코포레이티드 모발 성장을 촉진하기 위한 조성물 및 방법
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
CN101897949B (zh) * 2010-02-24 2016-07-06 温士顿医药股份有限公司 低刺激性透明乳化液剂型以供眼睛或眼睛周围有关组织表面免疫调节及消炎的眼用药物组合物
US20110294744A1 (en) * 2010-05-25 2011-12-01 Allergan, Inc. Cyclosporin emulsions
WO2012015211A2 (ko) * 2010-07-30 2012-02-02 주식회사종근당 사이클로스포린 에이 함유 점안제 조성물
US8501796B2 (en) 2010-09-16 2013-08-06 Allergan, Inc. Ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for lowering intraocular pressure
SG189880A1 (en) 2010-10-12 2013-06-28 Allergan Inc Cyclosporin analogs
US9175042B2 (en) 2010-10-12 2015-11-03 Allergan, Inc. Cyclosporin analogs
WO2012068515A2 (en) 2010-11-18 2012-05-24 Steven Yoelin Compositions and methods for hair growth
US9018202B2 (en) 2010-12-03 2015-04-28 Allergan, Inc. Methods for treating diseases of the retina
CN103282044B (zh) 2010-12-28 2016-07-06 韩林制药株式会社 纳米乳剂形态的眼科用组合物
US8859616B2 (en) 2011-01-21 2014-10-14 Allergan, Inc. Compounds and methods for enhancing hair growth
HUE037660T2 (hu) 2011-01-26 2018-09-28 Allergan Inc Androgén készítmény szembetegség kezelésére
ES2736256T3 (es) 2011-03-14 2019-12-27 Drug Delivery Solutions Ltd Composición oftálmica
MY180581A (en) * 2011-05-27 2020-12-02 Allergan Inc A crystalline form of cyclosporine a, methods of preparation, and methods for use thereof
BR112013034051A2 (pt) * 2011-06-29 2019-09-24 Allergan Inc formulações de macrogol 15 hidroxiestearato
US20130029919A1 (en) * 2011-07-26 2013-01-31 Allergan, Inc. Two part formulation system for opthalmic delivery
DE102011108948A1 (de) 2011-07-29 2013-01-31 Achim Göpferich Wässrige, kolloidale Lösungen von lipophilen Substanzen,insbesondere Arzneistofflösungen
EP2763649A2 (en) 2011-10-05 2014-08-13 Allergan, Inc. Compositions for enhancing nail health
BR112014008190A2 (pt) * 2011-10-05 2017-04-18 Allergan Inc composições para realce da saúde da unha
US8957048B2 (en) 2011-10-06 2015-02-17 Allergan, Inc. Compositions for the treatment of dry eye
US20130123194A1 (en) 2011-11-15 2013-05-16 Allergan, Inc. Autoclavable suspensions of cyclosporin a form 2
BR112014011770B1 (pt) 2011-11-15 2022-11-08 Allergan, Inc Suspensões da forma 2 de ciclosporina a
WO2013078151A1 (en) 2011-11-21 2013-05-30 Allergan, Inc. Pharmaceutical compositions comprising 4-[1-(2,3-dimethylphenyl)ethyl]-3h-imidazole derivatives for treating retinal diseases
US9907826B2 (en) 2011-12-07 2018-03-06 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
WO2013116186A1 (en) 2012-01-30 2013-08-08 Allergan, Inc. Brimonidine for treating visual disorders mediated by central visual projections from the eye
US9278132B2 (en) * 2012-02-13 2016-03-08 Bausch & Lomb Incorporated Ophthalmic pharmaceutical compositions and methods of making and using same
US20150164765A1 (en) 2012-05-17 2015-06-18 Steven G. Yoelin Compositions and methods for hair growth
WO2013181339A2 (en) 2012-06-01 2013-12-05 Allergan, Inc. Cyclosporin a analogs
SG11201507241UA (en) 2013-03-08 2015-10-29 Allergan Inc Cyclosporine a-steroid conjugates
KR101492447B1 (ko) 2013-05-20 2015-02-23 주식회사태준제약 사이클로스포린을 함유하는 나노에멀젼 점안 조성물 및 그의 제조 방법
BR112017001017A2 (pt) * 2014-07-18 2018-01-23 Allergan Inc composições em suspensão de ciclosporina a para injeção subconjuntival e periocular
US10279005B2 (en) 2014-11-25 2019-05-07 Allergan, Inc. Stabilized omega-3 ophthalmic compositions
WO2016112321A1 (en) 2015-01-08 2016-07-14 Allergan, Inc. Cyclosporin derivatives wherein the mebmt sidechain has been cyclized
US11324800B2 (en) 2015-01-15 2022-05-10 Wellspring Ophthalmics, Inc. Aqueous suspensions of cyclosporin
US20200237859A1 (en) 2019-01-25 2020-07-30 Newport Research, Inc. Aqueous suspensions of cyclosporin
US10413508B2 (en) 2015-02-06 2019-09-17 R. P. Scherer Technologies, Llc Preparation of an oil-in-water emulsion for polymer stabilized pharmaceutical formulations
US10077289B2 (en) 2015-03-31 2018-09-18 Allergan, Inc. Cyclosporins modified on the MeBmt sidechain by heterocyclic rings
KR101587385B1 (ko) 2015-07-29 2016-01-21 국제약품공업주식회사 사이클로스포린 함유 무자극성의 안약조성물 및 편리한 제조방법
US9820954B2 (en) 2015-08-19 2017-11-21 Jenivision Inc. Quantitative peri-orbital application of ophthalmology drugs
FR3041883B1 (fr) * 2015-10-02 2019-03-15 Chu Clermont-Ferrand Procede de preparation d'un collyre de ciclosporine a
EP3362096B1 (en) 2015-10-14 2023-12-13 Paul Gavaris Ophthalmic treatment composition and vehicle for delivery of pharmaceutical substances or therapeutic agents
CN106692052B (zh) * 2015-11-13 2021-03-26 天津金耀集团有限公司 一种环孢素眼用乳剂组合物
JP7044714B2 (ja) * 2016-11-17 2022-03-30 千寿製薬株式会社 乳剤点眼液
KR102115158B1 (ko) 2016-11-29 2020-05-26 주식회사 지트리파마슈티컬 티모신 베타 4 를 함유하는 제형
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis
USD841152S1 (en) 2017-06-27 2019-02-19 Monica S. Naylor Eye drop container
EP3542788A1 (en) 2018-03-19 2019-09-25 MC2 Therapeutics Limited Topical composition comprising calcipotriol and betamethasone dipropionate
CN109010268B (zh) * 2018-09-28 2020-07-10 湖北远大天天明制药有限公司 一种提高氯霉素稳定性的眼用组合物及其制备方法
WO2020250252A1 (en) 2019-06-11 2020-12-17 Sifi S.P.A. Microemulsion compositions
WO2021008668A1 (en) * 2019-07-12 2021-01-21 Pharmathen S.A. Preservative free pharmaceutical composition for ophthalmic administration containing cyclosporine
EP3886799B1 (en) 2019-08-07 2023-11-15 Aneira Pharma, Inc. Compositions for the treatment of hair loss
GR1010012B (el) * 2020-05-12 2021-05-27 Φαρματεν Α.Β.Ε.Ε. Φαρμακευτικο σκευασμα ελευθερο συντηρητικου για οφθαλμικη χορηγηση περιεχον κυκλοσπορινη
CN113749092A (zh) * 2020-06-03 2021-12-07 迈克斯(如东)化工有限公司 不饱和脂肪酸酯化物应用、农化组合物和低眼刺农药制剂及其应用
IL294896A (en) * 2022-07-20 2024-02-01 LYOTROPIC DELIVERY SYSTEMS Ltd Topical administration of cyclosporine to the eye

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH204625A (de) * 1937-07-13 1939-05-15 Telefunken Gmbh Eisenkernspule mit als Drehkondensator ausgebildetem Abgleichkondensator.
US2224205A (en) * 1938-07-18 1940-12-10 Hoover Co Suction cleaner
EP0028110B1 (en) * 1979-10-26 1984-03-07 Smith and Nephew Associated Companies p.l.c. Autoclavable emulsions
JPS59196816A (ja) * 1983-04-22 1984-11-08 Senjiyu Seiyaku Kk 水溶性アズレン誘導体の安定な水溶液の製造法
GB8903804D0 (en) * 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
US4649047A (en) * 1985-03-19 1987-03-10 University Of Georgia Research Foundation, Inc. Ophthalmic treatment by topical administration of cyclosporin
JP2577049B2 (ja) * 1987-06-04 1997-01-29 三共株式会社 シクロスポリン製剤
US4839342A (en) * 1987-09-03 1989-06-13 University Of Georgia Research Foundation, Inc. Method of increasing tear production by topical administration of cyclosporin
WO1989001772A1 (en) * 1987-09-03 1989-03-09 University Of Georgia Research Foundation, Inc. Ocular cyclosporin composition
CA1326995C (en) * 1988-01-29 1994-02-15 Kozo Kurihara Cyclosporin compositions
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
US5364632A (en) * 1989-04-05 1994-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
CA2052950A1 (en) * 1990-10-10 1992-04-11 David P. Evitts Aqueous ophthalmic microemulsions of tepoxalin
JPH0558906A (ja) * 1991-09-06 1993-03-09 Sankyo Co Ltd シクロスポリン点眼製剤
JPH06219949A (ja) * 1993-01-25 1994-08-09 Mitsubishi Kasei Corp 抗トロンビン剤及びその製造方法

Also Published As

Publication number Publication date
GR3036945T3 (en) 2002-01-31
DE69529932D1 (de) 2003-04-17
AU2640995A (en) 1995-12-05
ATE234076T1 (de) 2003-03-15
DE69522104D1 (de) 2001-09-13
BR9507664A (pt) 1997-10-07
WO1995031211A1 (en) 1995-11-23
DE69522104T2 (de) 2002-04-25
JP4119284B2 (ja) 2008-07-16
JP3441462B2 (ja) 2003-09-02
NZ287635A (en) 1998-09-24
CN1198587C (zh) 2005-04-27
CA2190485C (en) 2003-04-15
JP2003231646A (ja) 2003-08-19
EP0759773A1 (en) 1997-03-05
US5474979A (en) 1995-12-12
EP0759773B1 (en) 2001-08-08
MX9605599A (es) 1998-08-30
CN1152876A (zh) 1997-06-25
EP1044678A1 (en) 2000-10-18
KR100368181B1 (ko) 2003-04-10
DK1044678T3 (da) 2003-07-14
KR100450703B1 (ko) 2004-10-01
CA2190485A1 (en) 1995-11-23
PT759773E (pt) 2002-02-28
ATE203911T1 (de) 2001-08-15
DE69529932T2 (de) 2003-12-18
AU693213B2 (en) 1998-06-25
CN1288722A (zh) 2001-03-28
JPH10500414A (ja) 1998-01-13
EP1044678B1 (en) 2003-03-12
ES2194670T3 (es) 2003-12-01
HK1034190A1 (en) 2001-10-19
PT1044678E (pt) 2003-08-29
CN1229136C (zh) 2005-11-30
ES2161895T3 (es) 2001-12-16

Similar Documents

Publication Publication Date Title
DK0759773T3 (da) Tårekirtelspecifikke emulsioner til topisk påføring på okulært væv
DE50013111D1 (de) Kosmetische und dermatologische Zubereitungen auf der Grundlage von O/W-Emulsionen
ATE141780T1 (de) Öl in wasser emulsionen verwendbar für die herstellung von einer creme
DE50012804D1 (de) Kosmetische und dermatologische Zubereitungen auf der Grundlage von O/W-Emulsionen
ATE283031T1 (de) Nichtirritierende kosmetische und pharmazeutische zusammensetzungen
FR2702391B1 (fr) Nouvelles émulsions multiples, leur préparation, leur application à la préparation de compositions cosmétiques et ces compositions cosmétiques.
DE69727849D1 (de) Cyclosporin-Emulsionen
ID19191A (id) Penstabilan retinoat yang tak stabil pada emulsi minyak dalam air untuk komposisi perawatan kulit
FR2696931B1 (fr) Emulsions eau dans l'huile à phase continue fluorohydrocarbonée et utilisation de certains tensioactifs siliconés pour leur préparation.
EP1072247A3 (de) Kosmetische und dermatologische Zubereitungen auf der Grundlage von O/W-Emulsionen
DE60000223D1 (de) O/W-Emulsion enthaltende Fibern und ihre Verwendung in der Kosmetik
FR2720228B1 (fr) Nouvelles compositions pesticides du type "émulsion huile dans l'eau".
TR200102995T2 (tr) PIT-emülsiyonların fermantasyon işlemlerinde kullanımı
DE69418892T2 (de) Selbstemulgierende formulierung zur bildung einer öl-in-wasser-emulsion
CA2309033A1 (en) Lacrimal gland specific emulsions for topical application to ocular tissue