ES2161895T3 - Emulsiones especificas de la glandula lagrimal para aplicacion topica a tejidos oculares. - Google Patents

Emulsiones especificas de la glandula lagrimal para aplicacion topica a tejidos oculares.

Info

Publication number
ES2161895T3
ES2161895T3 ES95921294T ES95921294T ES2161895T3 ES 2161895 T3 ES2161895 T3 ES 2161895T3 ES 95921294 T ES95921294 T ES 95921294T ES 95921294 T ES95921294 T ES 95921294T ES 2161895 T3 ES2161895 T3 ES 2161895T3
Authority
ES
Spain
Prior art keywords
lagrimal
gland
topical application
specific emulsions
fabrics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95921294T
Other languages
English (en)
Inventor
Shulin Ding
Walter L Tien
Orest Olejnik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Sales LLC
Original Assignee
Allergan Sales LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22918100&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2161895(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Sales LLC filed Critical Allergan Sales LLC
Application granted granted Critical
Publication of ES2161895T3 publication Critical patent/ES2161895T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Abstract

SE MUESTRA UNA COMPOSICION FARMACEUTICA EN LA FORMA DE UNA EMULSION NO IRRITANTE QUE INCLUYE AL MENOS UNA CICLOSPORINA EN UNA MEZCLA DE ADICION CON UN GLICERIDO DE ACIDO GRASO MAYOR Y POLISORBATO 80. MAS ESPECIALMENTE, LA CICLOSPORINA PUEDE SER UNA CICLOSPORINA A Y EL GLICERIDO DE ACIDO GRASO MAYOR PUEDE SER ACEITE DE CASTOR. SE HA VISTO QUE LA COMPOSICION TIENE UN ALTO NIVEL DE CONFORT Y ESCASO POTENCIAL PARA IRRITAR LA PIEL LO QUE LA HACE ADECUADA PARA LA DISTRIBUCION DE MEDICAMENTOS EN AREAS SENSIBLES COMO LOS TEJIDOS OCULARES Y MEJORA LA ABSORCION DE LA GLANDULA LAGRIMAL. ADEMAS LA COMPOSICION MANTIENE SU ESTABILIDAD DURANTE MAS DE NUEVE MESES SIN CRISTALIZACION DE LA CICLOSPORINA.
ES95921294T 1994-05-17 1995-05-17 Emulsiones especificas de la glandula lagrimal para aplicacion topica a tejidos oculares. Expired - Lifetime ES2161895T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/243,279 US5474979A (en) 1994-05-17 1994-05-17 Nonirritating emulsions for sensitive tissue

Publications (1)

Publication Number Publication Date
ES2161895T3 true ES2161895T3 (es) 2001-12-16

Family

ID=22918100

Family Applications (2)

Application Number Title Priority Date Filing Date
ES00202069T Expired - Lifetime ES2194670T3 (es) 1994-05-17 1995-05-17 Emulsiones especificas de glandula lagrimal para aplicacion topica al tejido ocular.
ES95921294T Expired - Lifetime ES2161895T3 (es) 1994-05-17 1995-05-17 Emulsiones especificas de la glandula lagrimal para aplicacion topica a tejidos oculares.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES00202069T Expired - Lifetime ES2194670T3 (es) 1994-05-17 1995-05-17 Emulsiones especificas de glandula lagrimal para aplicacion topica al tejido ocular.

Country Status (17)

Country Link
US (1) US5474979A (es)
EP (2) EP1044678B1 (es)
JP (2) JP3441462B2 (es)
KR (2) KR100368181B1 (es)
CN (2) CN1229136C (es)
AT (2) ATE203911T1 (es)
AU (1) AU693213B2 (es)
BR (1) BR9507664A (es)
CA (1) CA2190485C (es)
DE (2) DE69529932T2 (es)
DK (2) DK1044678T3 (es)
ES (2) ES2194670T3 (es)
GR (1) GR3036945T3 (es)
HK (1) HK1034190A1 (es)
NZ (1) NZ287635A (es)
PT (2) PT759773E (es)
WO (1) WO1995031211A1 (es)

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CN1198587C (zh) 2005-04-27
PT1044678E (pt) 2003-08-29
HK1034190A1 (en) 2001-10-19
EP0759773A1 (en) 1997-03-05
GR3036945T3 (en) 2002-01-31
CA2190485A1 (en) 1995-11-23
JPH10500414A (ja) 1998-01-13
NZ287635A (en) 1998-09-24
JP4119284B2 (ja) 2008-07-16
US5474979A (en) 1995-12-12
DE69522104D1 (de) 2001-09-13
EP0759773B1 (en) 2001-08-08
DK1044678T3 (da) 2003-07-14
CN1152876A (zh) 1997-06-25
EP1044678A1 (en) 2000-10-18
JP2003231646A (ja) 2003-08-19
PT759773E (pt) 2002-02-28
EP1044678B1 (en) 2003-03-12
DK0759773T3 (da) 2001-11-26
AU693213B2 (en) 1998-06-25
KR100450703B1 (ko) 2004-10-01
DE69529932T2 (de) 2003-12-18
DE69522104T2 (de) 2002-04-25
ES2194670T3 (es) 2003-12-01
ATE234076T1 (de) 2003-03-15
CN1288722A (zh) 2001-03-28
MX9605599A (es) 1998-08-30
CN1229136C (zh) 2005-11-30
CA2190485C (en) 2003-04-15
WO1995031211A1 (en) 1995-11-23
KR100368181B1 (ko) 2003-04-10
ATE203911T1 (de) 2001-08-15
AU2640995A (en) 1995-12-05
BR9507664A (pt) 1997-10-07
JP3441462B2 (ja) 2003-09-02
DE69529932D1 (de) 2003-04-17

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