TR200302105T4 - Siklosporin, hiyalüronik asit ve polisorbat içeren göz formülasyonları. - Google Patents
Siklosporin, hiyalüronik asit ve polisorbat içeren göz formülasyonları.Info
- Publication number
- TR200302105T4 TR200302105T4 TR2003/02105T TR200302105T TR200302105T4 TR 200302105 T4 TR200302105 T4 TR 200302105T4 TR 2003/02105 T TR2003/02105 T TR 2003/02105T TR 200302105 T TR200302105 T TR 200302105T TR 200302105 T4 TR200302105 T4 TR 200302105T4
- Authority
- TR
- Turkey
- Prior art keywords
- polysorbate
- hyaluronic acid
- formulations containing
- containing cyclosporine
- eye formulations
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 2
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 2
- 108010036949 Cyclosporine Proteins 0.000 title abstract 2
- 229960001265 ciclosporin Drugs 0.000 title abstract 2
- 229930182912 cyclosporin Natural products 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title abstract 2
- 229920002674 hyaluronan Polymers 0.000 title abstract 2
- 229960003160 hyaluronic acid Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 229950008882 polysorbate Drugs 0.000 title 1
- 229920000136 polysorbate Polymers 0.000 title 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 abstract 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 abstract 1
- 229920000053 polysorbate 80 Polymers 0.000 abstract 1
- 229940068968 polysorbate 80 Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
Abstract
Bir siklosporin, hiyalüronik asit ya da bunun bir tuzunu ve polisorbat 80 içeren, haricen kullanilan, sulu çözelti biçiminde bir göz formülasyonu anlatilmistir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH6942000 | 2000-04-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200302105T4 true TR200302105T4 (tr) | 2004-02-23 |
Family
ID=4529494
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2003/02105T TR200302105T4 (tr) | 2000-04-07 | 2001-03-23 | Siklosporin, hiyalüronik asit ve polisorbat içeren göz formülasyonları. |
Country Status (19)
Country | Link |
---|---|
US (2) | US6677304B2 (tr) |
EP (1) | EP1142566B1 (tr) |
JP (1) | JP2001316284A (tr) |
CN (1) | CN1185009C (tr) |
AR (1) | AR028291A1 (tr) |
AT (1) | ATE250924T1 (tr) |
AU (1) | AU778858B2 (tr) |
BR (1) | BR0101332A (tr) |
CA (1) | CA2342133C (tr) |
CZ (1) | CZ294385B6 (tr) |
DE (1) | DE60100866T2 (tr) |
DK (1) | DK1142566T3 (tr) |
ES (1) | ES2206363T3 (tr) |
IL (1) | IL142268A (tr) |
PL (1) | PL201055B1 (tr) |
PT (1) | PT1142566E (tr) |
SK (1) | SK285220B6 (tr) |
TR (1) | TR200302105T4 (tr) |
ZA (1) | ZA200102769B (tr) |
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WO1995032726A1 (en) * | 1994-06-01 | 1995-12-07 | Yuhan Corporation | Cyclosporin containing composition and process for the preparation thereof |
JPH1160505A (ja) * | 1997-05-20 | 1999-03-02 | Senju Pharmaceut Co Ltd | 防腐組成物 |
-
2001
- 2001-03-23 DE DE60100866T patent/DE60100866T2/de not_active Expired - Lifetime
- 2001-03-23 EP EP01107223A patent/EP1142566B1/fr not_active Expired - Lifetime
- 2001-03-23 AT AT01107223T patent/ATE250924T1/de active
- 2001-03-23 PT PT01107223T patent/PT1142566E/pt unknown
- 2001-03-23 ES ES01107223T patent/ES2206363T3/es not_active Expired - Lifetime
- 2001-03-23 TR TR2003/02105T patent/TR200302105T4/tr unknown
- 2001-03-23 DK DK01107223T patent/DK1142566T3/da active
- 2001-03-26 AR ARP010101408A patent/AR028291A1/es not_active Application Discontinuation
- 2001-03-27 CA CA2342133A patent/CA2342133C/en not_active Expired - Fee Related
- 2001-03-27 US US09/818,213 patent/US6677304B2/en not_active Expired - Fee Related
- 2001-03-27 IL IL142268A patent/IL142268A/en not_active IP Right Cessation
- 2001-04-04 AU AU33404/01A patent/AU778858B2/en not_active Ceased
- 2001-04-04 CZ CZ20011229A patent/CZ294385B6/cs not_active IP Right Cessation
- 2001-04-04 ZA ZA200102769A patent/ZA200102769B/xx unknown
- 2001-04-05 SK SK460-2001A patent/SK285220B6/sk not_active IP Right Cessation
- 2001-04-06 BR BR0101332-7A patent/BR0101332A/pt active Search and Examination
- 2001-04-06 PL PL346926A patent/PL201055B1/pl unknown
- 2001-04-06 CN CNB011124849A patent/CN1185009C/zh not_active Expired - Fee Related
- 2001-04-06 JP JP2001109077A patent/JP2001316284A/ja active Pending
-
2003
- 2003-11-21 US US10/721,007 patent/US6953776B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU3340401A (en) | 2001-10-11 |
IL142268A (en) | 2007-08-19 |
ES2206363T3 (es) | 2004-05-16 |
US6953776B2 (en) | 2005-10-11 |
DE60100866D1 (de) | 2003-11-06 |
PL201055B1 (pl) | 2009-03-31 |
ZA200102769B (en) | 2001-10-05 |
SK285220B6 (sk) | 2006-09-07 |
CZ294385B6 (cs) | 2004-12-15 |
CA2342133C (en) | 2011-02-01 |
PL346926A1 (en) | 2001-10-08 |
DE60100866T2 (de) | 2004-07-29 |
EP1142566A1 (fr) | 2001-10-10 |
US6677304B2 (en) | 2004-01-13 |
AU778858B2 (en) | 2004-12-23 |
CZ20011229A3 (cs) | 2001-11-14 |
JP2001316284A (ja) | 2001-11-13 |
DK1142566T3 (da) | 2004-02-09 |
US20040106546A1 (en) | 2004-06-03 |
US20010041671A1 (en) | 2001-11-15 |
ATE250924T1 (de) | 2003-10-15 |
CN1185009C (zh) | 2005-01-19 |
SK4602001A3 (en) | 2001-11-06 |
PT1142566E (pt) | 2004-02-27 |
CN1317342A (zh) | 2001-10-17 |
AR028291A1 (es) | 2003-04-30 |
IL142268A0 (en) | 2002-03-10 |
EP1142566B1 (fr) | 2003-10-01 |
BR0101332A (pt) | 2001-11-06 |
CA2342133A1 (en) | 2001-10-07 |
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