DE60039727D1 - Neue Zusammensetzung enthaltend eine bicyclische Verbindung und ein Glycerid - Google Patents

Neue Zusammensetzung enthaltend eine bicyclische Verbindung und ein Glycerid

Info

Publication number
DE60039727D1
DE60039727D1 DE60039727T DE60039727T DE60039727D1 DE 60039727 D1 DE60039727 D1 DE 60039727D1 DE 60039727 T DE60039727 T DE 60039727T DE 60039727 T DE60039727 T DE 60039727T DE 60039727 D1 DE60039727 D1 DE 60039727D1
Authority
DE
Germany
Prior art keywords
glyceride
composition containing
new composition
bicyclic compound
bicyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60039727T
Other languages
English (en)
Inventor
Ryuji Ueno
Tsuyoshi Habe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sucampo GmbH
Original Assignee
Sucampo GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22573018&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60039727(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sucampo GmbH filed Critical Sucampo GmbH
Application granted granted Critical
Publication of DE60039727D1 publication Critical patent/DE60039727D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
DE60039727T 1999-10-15 2000-10-13 Neue Zusammensetzung enthaltend eine bicyclische Verbindung und ein Glycerid Expired - Lifetime DE60039727D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15954999P 1999-10-15 1999-10-15

Publications (1)

Publication Number Publication Date
DE60039727D1 true DE60039727D1 (de) 2008-09-11

Family

ID=22573018

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60010913T Expired - Lifetime DE60010913T2 (de) 1999-10-15 2000-10-13 Bizyklische Verbindungen, Zusammenstellung und Verfahren zu ihrer Stabilisierung
DE60039727T Expired - Lifetime DE60039727D1 (de) 1999-10-15 2000-10-13 Neue Zusammensetzung enthaltend eine bicyclische Verbindung und ein Glycerid

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60010913T Expired - Lifetime DE60010913T2 (de) 1999-10-15 2000-10-13 Bizyklische Verbindungen, Zusammenstellung und Verfahren zu ihrer Stabilisierung

Country Status (26)

Country Link
US (5) US6583174B1 (de)
EP (2) EP1426361B2 (de)
JP (2) JP4332316B2 (de)
KR (1) KR100830061B1 (de)
CN (1) CN1268623C (de)
AR (3) AR026046A1 (de)
AT (2) ATE267189T1 (de)
AU (2) AU780342B2 (de)
BR (1) BRPI0014869B8 (de)
CA (1) CA2385732C (de)
CZ (1) CZ303625B6 (de)
DE (2) DE60010913T2 (de)
DK (2) DK1426361T4 (de)
ES (2) ES2221859T3 (de)
HK (2) HK1066792A1 (de)
HU (2) HU229547B1 (de)
IL (2) IL148803A0 (de)
MX (1) MXPA02003756A (de)
NO (1) NO330258B1 (de)
NZ (1) NZ518020A (de)
PT (2) PT1220849E (de)
RU (1) RU2695274C3 (de)
TR (1) TR200201032T2 (de)
TW (1) TWI281918B (de)
WO (1) WO2001027099A2 (de)
ZA (1) ZA200202312B (de)

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EP1562604B1 (de) * 2002-10-23 2012-01-04 Sucampo AG Prostaglandinsubstanzen für die behandlung von fettsucht
EP2281564A3 (de) * 2002-12-27 2012-09-05 Sucampo AG Prostaglandinderivate zur Behandlung von abdominalen Schmerzen
JP5294559B2 (ja) * 2003-07-03 2013-09-18 スキャンポ・アーゲー クロライドチャンネルオープナーとしてプロスタグランジンアナログを含む腸溶性組成物
TWI348386B (en) * 2003-08-12 2011-09-11 R Tech Ueno Ltd Composition and method for promoting hair growth
TWI387454B (zh) 2004-09-02 2013-03-01 Sucampo Ag 治療胃腸道疾病之方法及組成物
CN101198334B (zh) * 2005-04-12 2013-02-06 苏坎波公司 前列腺素化合物和质子泵抑制剂用于治疗肠胃病的联合应用
CN101466407B (zh) 2006-01-24 2013-05-15 株式会社·R-技术上野 包含双环化合物的药物组合物和使所述双环化合物稳定的方法
AU2007208632B2 (en) * 2006-01-24 2012-01-19 R-Tech Ueno, Ltd. Soft-gelatin capsule formulation
CN103804338A (zh) * 2006-02-07 2014-05-21 株式会社·R-技术上野 用于制备前列腺素衍生物的方法
US20090012165A1 (en) 2007-07-03 2009-01-08 Sucampo Ag Pharmaceutical combination of nsaid and prostaglandin compound
US20090030072A1 (en) 2007-07-03 2009-01-29 Sucampo Ag Pharmaceutical combination of opioid and prostaglandin compound
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US8569279B2 (en) * 2009-05-27 2013-10-29 Sucampo Ag Method for modulating claudin mediated functions
US20110034424A1 (en) * 2009-06-30 2011-02-10 Sucampo Ag Method for the long term nsaid use
EP2460801B1 (de) 2009-07-28 2014-06-25 ONO Pharmaceutical Co., Ltd. Bizyklische verbindung und ihre verwendung für medizinische zwecke
CN104958298A (zh) * 2009-09-18 2015-10-07 阿得罗公司 阿片样受体拮抗剂用于胃肠道疾病的用途
CA2779736A1 (en) * 2009-11-03 2011-05-12 Bernard Charles Sherman Stable pharmaceutical formulations comprising lubiprostone
JP5907077B2 (ja) 2011-01-27 2016-04-20 小野薬品工業株式会社 二環式化合物およびその医薬用途
EP2669279B1 (de) 2011-01-27 2017-01-11 ONO Pharmaceutical Co., Ltd. Bizyklische verbindung und ihre verwendung für medizinische zwecke
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
EP3277274A4 (de) 2015-04-01 2018-12-05 Cedars-Sinai Medical Center Antimethanogene lovastatin-analoga oder -derivate und verwendungen davon
ES2890989T3 (es) 2016-06-30 2022-01-25 Ono Pharmaceutical Co Método para producir un compuesto bicíclico
US11534404B2 (en) 2016-10-06 2022-12-27 Sucampo Ag Multilayer beads for pharmaceutical use
JPWO2019221215A1 (ja) * 2018-05-18 2021-05-27 ニプロ株式会社 ルビプロストン含有粒子状医薬組成物

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Also Published As

Publication number Publication date
HU229547B1 (en) 2014-01-28
DK1426361T4 (en) 2015-03-16
AU780342B2 (en) 2005-03-17
EP1220849B1 (de) 2004-05-19
EP1426361B2 (de) 2015-02-25
AU2004242503C1 (en) 2005-01-27
CZ303625B6 (cs) 2013-01-16
KR100830061B1 (ko) 2008-05-16
PT1220849E (pt) 2004-10-29
TWI281918B (en) 2007-06-01
US20080255227A1 (en) 2008-10-16
CZ20021037A3 (cs) 2002-09-11
IL148803A0 (en) 2002-09-12
DE60010913T2 (de) 2005-06-09
HUP0203746A3 (en) 2005-02-28
US20120095090A1 (en) 2012-04-19
US7417067B2 (en) 2008-08-26
ATE402925T2 (de) 2008-08-15
US8097649B1 (en) 2012-01-17
ZA200202312B (en) 2002-12-24
JP2009235079A (ja) 2009-10-15
RU2695274C9 (ru) 2020-01-22
WO2001027099A3 (en) 2001-10-25
AU2004242503A1 (en) 2005-01-27
DK1220849T3 (da) 2004-09-27
AR089848A2 (es) 2014-09-24
EP1220849A2 (de) 2002-07-10
ES2309410T3 (es) 2008-12-16
US6583174B1 (en) 2003-06-24
RU2002112984A (ru) 2004-01-20
HK1045693B (zh) 2005-01-21
ES2309410T5 (es) 2015-03-17
MXPA02003756A (es) 2005-09-08
BR0014869A (pt) 2002-06-25
US20040235885A1 (en) 2004-11-25
WO2001027099A2 (en) 2001-04-19
NO20021736L (no) 2002-04-12
BRPI0014869B1 (pt) 2017-06-13
RU2695274C3 (ru) 2020-11-09
AU7685600A (en) 2001-04-23
DE60010913D1 (de) 2004-06-24
AU2004242503B2 (en) 2007-06-21
BRPI0014869B8 (pt) 2021-05-25
HK1066792A1 (en) 2005-04-01
KR20020068521A (ko) 2002-08-27
ES2221859T3 (es) 2005-01-16
HU230484B1 (hu) 2016-07-28
RU2695274C2 (ru) 2019-07-22
CA2385732A1 (en) 2001-04-19
NO330258B1 (no) 2011-03-14
IL148803A (en) 2006-07-05
HUP1300369A2 (de) 2003-03-28
TR200201032T2 (tr) 2002-08-21
NZ518020A (en) 2004-02-27
PT1426361E (pt) 2008-10-08
HK1045693A1 (en) 2002-12-06
ATE267189T1 (de) 2004-06-15
AR109354A2 (es) 2018-11-21
EP1426361B1 (de) 2008-07-30
JP2003511445A (ja) 2003-03-25
AR026046A1 (es) 2002-12-26
CN1268623C (zh) 2006-08-09
JP4332316B2 (ja) 2009-09-16
NO20021736D0 (no) 2002-04-12
US8088934B2 (en) 2012-01-03
CN1379769A (zh) 2002-11-13
DK1426361T3 (da) 2008-11-17
EP1426361A1 (de) 2004-06-09
CA2385732C (en) 2009-02-10
HUP0203746A2 (hu) 2003-03-28

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