HK1066792A1 - Novel composition containing a bi-cyclic compound and a glyceride - Google Patents

Novel composition containing a bi-cyclic compound and a glyceride

Info

Publication number
HK1066792A1
HK1066792A1 HK04109640.1A HK04109640A HK1066792A1 HK 1066792 A1 HK1066792 A1 HK 1066792A1 HK 04109640 A HK04109640 A HK 04109640A HK 1066792 A1 HK1066792 A1 HK 1066792A1
Authority
HK
Hong Kong
Prior art keywords
glyceride
composition containing
cyclic compound
novel composition
novel
Prior art date
Application number
HK04109640.1A
Other languages
English (en)
Inventor
Ryuji Ueno
Tsuyoshi Habe
Original Assignee
Sucampo Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22573018&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1066792(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sucampo Ag filed Critical Sucampo Ag
Publication of HK1066792A1 publication Critical patent/HK1066792A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
HK04109640.1A 1999-10-15 2002-10-07 Novel composition containing a bi-cyclic compound and a glyceride HK1066792A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15954999P 1999-10-15 1999-10-15
HK02107337.5A HK1045693B (zh) 1999-10-15 2002-10-07 新組合物和使該組合物穩定的方法

Publications (1)

Publication Number Publication Date
HK1066792A1 true HK1066792A1 (en) 2005-04-01

Family

ID=22573018

Family Applications (2)

Application Number Title Priority Date Filing Date
HK04109640.1A HK1066792A1 (en) 1999-10-15 2002-10-07 Novel composition containing a bi-cyclic compound and a glyceride
HK02107337.5A HK1045693B (zh) 1999-10-15 2002-10-07 新組合物和使該組合物穩定的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK02107337.5A HK1045693B (zh) 1999-10-15 2002-10-07 新組合物和使該組合物穩定的方法

Country Status (26)

Country Link
US (5) US6583174B1 (de)
EP (2) EP1220849B1 (de)
JP (2) JP4332316B2 (de)
KR (1) KR100830061B1 (de)
CN (1) CN1268623C (de)
AR (3) AR026046A1 (de)
AT (2) ATE402925T2 (de)
AU (2) AU780342B2 (de)
BR (1) BRPI0014869B8 (de)
CA (1) CA2385732C (de)
CZ (1) CZ303625B6 (de)
DE (2) DE60039727D1 (de)
DK (2) DK1426361T4 (de)
ES (2) ES2309410T5 (de)
HK (2) HK1066792A1 (de)
HU (2) HU229547B1 (de)
IL (2) IL148803A0 (de)
MX (1) MXPA02003756A (de)
NO (1) NO330258B1 (de)
NZ (1) NZ518020A (de)
PT (2) PT1220849E (de)
RU (1) RU2695274C3 (de)
TR (1) TR200201032T2 (de)
TW (1) TWI281918B (de)
WO (1) WO2001027099A2 (de)
ZA (1) ZA200202312B (de)

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JP4332316B2 (ja) * 1999-10-15 2009-09-16 スキャンポ・アーゲー 二環式化合物組成物およびその安定化方法
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
TWI331920B (en) 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
FR2842810B1 (fr) * 2002-07-25 2006-01-27 Inst Nat Sciences Appliq Nouveaux composes gem difluores, leur procedes de preparation et leurs applications.
ES2379652T3 (es) * 2002-10-23 2012-04-30 Sucampo Ag Compuestos de prostaglandina para el tratamiento de obesidad
CA2510051C (en) * 2002-12-27 2016-07-05 Sucampo Ag Derivatives of prostaglandins for treating abdominal discomfort
DE602004030245D1 (de) * 2003-07-03 2011-01-05 Sucampo Ag Pharmazeutische magensaftresistent überzogene zusammensetzung enthaltend prostaglandin-analoga als chloridkanalöffner
TWI348386B (en) * 2003-08-12 2011-09-11 R Tech Ueno Ltd Composition and method for promoting hair growth
TWI387454B (zh) 2004-09-02 2013-03-01 Sucampo Ag 治療胃腸道疾病之方法及組成物
PL1871380T3 (pl) * 2005-04-12 2012-03-30 Sucampo Ag Zastosowanie kombinacji związku prostaglandyny i inhibitora pompy protonowej w leczeniu zaburzeń żołądkowo-jelitowych
EP1978944B1 (de) 2006-01-24 2012-08-15 R-Tech Ueno, Ltd. Weichgelatinkapselformulierung
EP1984027B1 (de) 2006-01-24 2015-12-30 R-Tech Ueno, Ltd. Pharmazeutische zusammensetzung mit einer bizyklischen verbindung sowie verfahren zur stabilisierung der bicyclischen verbindung
CN103755737A (zh) * 2006-02-07 2014-04-30 株式会社·R-技术上野 用于制备前列腺素衍生物的方法
US20090012165A1 (en) 2007-07-03 2009-01-08 Sucampo Ag Pharmaceutical combination of nsaid and prostaglandin compound
US20090030072A1 (en) 2007-07-03 2009-01-29 Sucampo Ag Pharmaceutical combination of opioid and prostaglandin compound
US8969324B2 (en) * 2007-07-19 2015-03-03 R-Tech Ueno, Ltd. Pharmaceutical composition comprising 11-deoxy-prostaglandin compound and method for stabilizing the compound
US20090082442A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched lubiprostone
CN101318948B (zh) * 2008-04-01 2011-04-27 上海天伟生物制药有限公司 鲁比前列酮晶体、其制备方法及用途
US8569279B2 (en) * 2009-05-27 2013-10-29 Sucampo Ag Method for modulating claudin mediated functions
US20110034424A1 (en) * 2009-06-30 2011-02-10 Sucampo Ag Method for the long term nsaid use
ES2567328T3 (es) 2009-07-28 2016-04-21 Ono Pharmaceutical Co., Ltd. Compuesto bicíclico y uso del mismo para fines médicos
US20110071163A1 (en) * 2009-09-18 2011-03-24 Adolor Corporation Use of an opioid receptor antagonist for the treatment or prevention of gastrointestinal tract disorders
US8940790B2 (en) 2009-11-03 2015-01-27 Bernard Charles Sherman Stable pharmaceutical formulations comprising lubiprostone
ES2581852T3 (es) 2011-01-27 2016-09-07 Ono Pharmaceutical Co., Ltd. Compuesto bicíclico y uso del mismo para fines médicos
EP2669279B1 (de) 2011-01-27 2017-01-11 ONO Pharmaceutical Co., Ltd. Bizyklische verbindung und ihre verwendung für medizinische zwecke
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
US10736871B2 (en) 2015-04-01 2020-08-11 Cedars-Sinai Medical Center Anti-methanogenic lovastatin analogs or derivatives and uses thereof
US10899729B2 (en) 2016-06-30 2021-01-26 Ono Pharmaceutical Co.. Ltd. Method for producing bicyclic compound
WO2018065826A1 (en) 2016-10-06 2018-04-12 Sucampo Ag Multilayer beads for pharmaceutical use
WO2019221215A1 (ja) * 2018-05-18 2019-11-21 ニプロ株式会社 ルビプロストン含有粒子状医薬組成物

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Also Published As

Publication number Publication date
RU2695274C2 (ru) 2019-07-22
ZA200202312B (en) 2002-12-24
HU230484B1 (hu) 2016-07-28
EP1426361B2 (de) 2015-02-25
HUP1300369A2 (de) 2003-03-28
EP1426361A1 (de) 2004-06-09
CN1379769A (zh) 2002-11-13
HK1045693B (zh) 2005-01-21
IL148803A0 (en) 2002-09-12
HUP0203746A2 (hu) 2003-03-28
ES2309410T5 (es) 2015-03-17
US7417067B2 (en) 2008-08-26
DK1426361T3 (da) 2008-11-17
NO20021736L (no) 2002-04-12
PT1426361E (pt) 2008-10-08
US6583174B1 (en) 2003-06-24
NZ518020A (en) 2004-02-27
HU229547B1 (en) 2014-01-28
KR20020068521A (ko) 2002-08-27
DK1220849T3 (da) 2004-09-27
CZ20021037A3 (cs) 2002-09-11
PT1220849E (pt) 2004-10-29
TWI281918B (en) 2007-06-01
KR100830061B1 (ko) 2008-05-16
AU2004242503B2 (en) 2007-06-21
DK1426361T4 (en) 2015-03-16
ATE402925T2 (de) 2008-08-15
CZ303625B6 (cs) 2013-01-16
TR200201032T2 (tr) 2002-08-21
HK1045693A1 (en) 2002-12-06
CN1268623C (zh) 2006-08-09
IL148803A (en) 2006-07-05
BR0014869A (pt) 2002-06-25
EP1220849B1 (de) 2004-05-19
AU7685600A (en) 2001-04-23
JP2009235079A (ja) 2009-10-15
US20080255227A1 (en) 2008-10-16
AU780342B2 (en) 2005-03-17
ES2221859T3 (es) 2005-01-16
NO330258B1 (no) 2011-03-14
CA2385732A1 (en) 2001-04-19
US8097649B1 (en) 2012-01-17
BRPI0014869B8 (pt) 2021-05-25
US20120095090A1 (en) 2012-04-19
US20040235885A1 (en) 2004-11-25
BRPI0014869B1 (pt) 2017-06-13
WO2001027099A3 (en) 2001-10-25
CA2385732C (en) 2009-02-10
DE60010913T2 (de) 2005-06-09
JP4332316B2 (ja) 2009-09-16
ATE267189T1 (de) 2004-06-15
DE60010913D1 (de) 2004-06-24
JP2003511445A (ja) 2003-03-25
AU2004242503C1 (en) 2005-01-27
RU2695274C3 (ru) 2020-11-09
NO20021736D0 (no) 2002-04-12
AU2004242503A1 (en) 2005-01-27
AR109354A2 (es) 2018-11-21
DE60039727D1 (de) 2008-09-11
ES2309410T3 (es) 2008-12-16
WO2001027099A2 (en) 2001-04-19
RU2695274C9 (ru) 2020-01-22
AR026046A1 (es) 2002-12-26
EP1426361B1 (de) 2008-07-30
MXPA02003756A (es) 2005-09-08
AR089848A2 (es) 2014-09-24
EP1220849A2 (de) 2002-07-10
US8088934B2 (en) 2012-01-03
HUP0203746A3 (en) 2005-02-28
RU2002112984A (ru) 2004-01-20

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PE Patent expired

Effective date: 20201012