AR109354A2 - Una composición que comprende un compuesto bicíclico y compuesto - Google Patents
Una composición que comprende un compuesto bicíclico y compuestoInfo
- Publication number
- AR109354A2 AR109354A2 ARP170102288A ARP170102288A AR109354A2 AR 109354 A2 AR109354 A2 AR 109354A2 AR P170102288 A ARP170102288 A AR P170102288A AR P170102288 A ARP170102288 A AR P170102288A AR 109354 A2 AR109354 A2 AR 109354A2
- Authority
- AR
- Argentina
- Prior art keywords
- compound
- composition according
- glyceride
- composition
- bicyclic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
Abstract
Composición que comprende un compuesto bicíclico, de fórmula (1), que se espera que sea farmacéuticamente activo y un glicérido. Reivindicación 2: La composición de acuerdo con la reivindicación 1, caracterizada porque el glicérido es un glicérido de un ácido graso que tiene 6 - 24 átomos de carbono. Reivindicación 5: La composición de acuerdo con la reivindicación 1, caracterizada porque dicho glicérido se mezcla con el otro solvente oleoso. Reivindicación 6: La composición de acuerdo con la reivindicación 5, caracterizada porque el otro solvente oleoso mencionado es un aceite mineral. Reivindicación 8: La composición de acuerdo con la reivindicación 7, caracterizada porque es formulada como cápsula. Reivindicación 10: La composición de acuerdo con la reivindicación 9, caracterizada porque es formulada como gotas oftálmicas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15954999P | 1999-10-15 | 1999-10-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR109354A2 true AR109354A2 (es) | 2018-11-21 |
Family
ID=22573018
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000105407A AR026046A1 (es) | 1999-10-15 | 2000-10-13 | NUEVA COMPOSICIoN Y MÉTODO PARA ESTABILIZAR LA MISMA |
ARP130100275A AR089848A2 (es) | 1999-10-15 | 2013-01-30 | Un compuesto biciclico, composicion farmaceutica y metodo para estabilizarlo |
ARP170102288A AR109354A2 (es) | 1999-10-15 | 2017-08-16 | Una composición que comprende un compuesto bicíclico y compuesto |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000105407A AR026046A1 (es) | 1999-10-15 | 2000-10-13 | NUEVA COMPOSICIoN Y MÉTODO PARA ESTABILIZAR LA MISMA |
ARP130100275A AR089848A2 (es) | 1999-10-15 | 2013-01-30 | Un compuesto biciclico, composicion farmaceutica y metodo para estabilizarlo |
Country Status (26)
Country | Link |
---|---|
US (5) | US6583174B1 (es) |
EP (2) | EP1426361B2 (es) |
JP (2) | JP4332316B2 (es) |
KR (1) | KR100830061B1 (es) |
CN (1) | CN1268623C (es) |
AR (3) | AR026046A1 (es) |
AT (2) | ATE267189T1 (es) |
AU (2) | AU780342B2 (es) |
BR (1) | BRPI0014869B8 (es) |
CA (1) | CA2385732C (es) |
CZ (1) | CZ303625B6 (es) |
DE (2) | DE60039727D1 (es) |
DK (2) | DK1426361T4 (es) |
ES (2) | ES2309410T5 (es) |
HK (2) | HK1066792A1 (es) |
HU (2) | HU230484B1 (es) |
IL (2) | IL148803A0 (es) |
MX (1) | MXPA02003756A (es) |
NO (1) | NO330258B1 (es) |
NZ (1) | NZ518020A (es) |
PT (2) | PT1426361E (es) |
RU (1) | RU2695274C3 (es) |
TR (1) | TR200201032T2 (es) |
TW (1) | TWI281918B (es) |
WO (1) | WO2001027099A2 (es) |
ZA (1) | ZA200202312B (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2385732C (en) * | 1999-10-15 | 2009-02-10 | Sucampo Ag | Bicyclic compounds composition and method for stabilizing the same |
US6414016B1 (en) * | 2000-09-05 | 2002-07-02 | Sucampo, A.G. | Anti-constipation composition |
TWI331920B (en) * | 2001-11-14 | 2010-10-21 | Sucampo Ag | Unit dosage form for relieving or treating constipation in human patients |
FR2842810B1 (fr) * | 2002-07-25 | 2006-01-27 | Inst Nat Sciences Appliq | Nouveaux composes gem difluores, leur procedes de preparation et leurs applications. |
US8114911B2 (en) * | 2002-10-23 | 2012-02-14 | Sucampo Ag | Prostaglandin compounds for the treatment of obesity |
WO2004060377A1 (en) * | 2002-12-27 | 2004-07-22 | Sucampo Ag | Derivatives of prostaglandins for treating abdominal discomfort |
US8337891B2 (en) * | 2003-07-03 | 2012-12-25 | Sucampo Ag | Enteric coated composition comprising prostaglandin analogs as chloride channel opener |
TWI495471B (zh) * | 2003-08-12 | 2015-08-11 | R Tech Ueno Ltd | 促進毛髮生長之組成物及方法 |
TWI387454B (zh) | 2004-09-02 | 2013-03-01 | Sucampo Ag | 治療胃腸道疾病之方法及組成物 |
PL1871380T3 (pl) * | 2005-04-12 | 2012-03-30 | Sucampo Ag | Zastosowanie kombinacji związku prostaglandyny i inhibitora pompy protonowej w leczeniu zaburzeń żołądkowo-jelitowych |
DK1978944T3 (da) | 2006-01-24 | 2012-11-05 | Sucampo Ag | Blød-gelatine-kapselformulering |
KR20140147142A (ko) * | 2006-01-24 | 2014-12-29 | 가부시키가이샤 아루떼꾸 우에노 | 바이-사이클릭 화합물을 함유하는 약학적 조성물 및 바이-사이클릭 화합물의 안정화 방법 |
EP1981867B1 (en) * | 2006-02-07 | 2017-06-14 | R-Tech Ueno, Ltd. | Method for preparing prostaglandin derivative |
US20090012165A1 (en) | 2007-07-03 | 2009-01-08 | Sucampo Ag | Pharmaceutical combination of nsaid and prostaglandin compound |
US20090030072A1 (en) | 2007-07-03 | 2009-01-29 | Sucampo Ag | Pharmaceutical combination of opioid and prostaglandin compound |
KR101485212B1 (ko) * | 2007-07-19 | 2015-01-22 | 가부시키가이샤 아루떼꾸 우에노 | 11-데옥시-프로스타글란딘 화합물을 포함하는 약학 조성물 및 상기 화합물을 안정화시키는 방법 |
US20090082442A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched lubiprostone |
CN101318948B (zh) | 2008-04-01 | 2011-04-27 | 上海天伟生物制药有限公司 | 鲁比前列酮晶体、其制备方法及用途 |
US8569279B2 (en) * | 2009-05-27 | 2013-10-29 | Sucampo Ag | Method for modulating claudin mediated functions |
US20110034424A1 (en) * | 2009-06-30 | 2011-02-10 | Sucampo Ag | Method for the long term nsaid use |
DK2653468T3 (en) | 2009-07-28 | 2016-06-06 | Ono Pharmaceutical Co | Bicyclic compound AND USE THEREOF FOR MEDICAL PURPOSES |
TW201118084A (en) * | 2009-09-18 | 2011-06-01 | Adolor Corp | The use of an opioid receptor antagonist for the treatment or prevention of gastrointestinal tract disorders |
US8940790B2 (en) | 2009-11-03 | 2015-01-27 | Bernard Charles Sherman | Stable pharmaceutical formulations comprising lubiprostone |
EP2669280B1 (en) | 2011-01-27 | 2016-04-27 | ONO Pharmaceutical Co., Ltd. | Bicyclic compound and use thereof for medical purposes |
EP2669279B1 (en) | 2011-01-27 | 2017-01-11 | ONO Pharmaceutical Co., Ltd. | Bicyclic compound and use thereof for medical purposes |
WO2014159679A1 (en) | 2013-03-12 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for using lubiprostone to absorb fluid from the subretinal space |
US10736871B2 (en) | 2015-04-01 | 2020-08-11 | Cedars-Sinai Medical Center | Anti-methanogenic lovastatin analogs or derivatives and uses thereof |
JP6954282B2 (ja) | 2016-06-30 | 2021-10-27 | 小野薬品工業株式会社 | 二環式化合物の製造方法 |
US11534404B2 (en) | 2016-10-06 | 2022-12-27 | Sucampo Ag | Multilayer beads for pharmaceutical use |
JPWO2019221215A1 (ja) * | 2018-05-18 | 2021-05-27 | ニプロ株式会社 | ルビプロストン含有粒子状医薬組成物 |
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CA2046069C (en) | 1990-07-10 | 2002-04-09 | Ryuji Ueno | Treatment of inflammatory diseases with 15-keto-prostaglandin compounds |
JP2938579B2 (ja) | 1990-12-15 | 1999-08-23 | 株式会社上野製薬応用研究所 | 消化管壁保護剤 |
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CA2150287C (en) | 1994-06-03 | 2004-08-10 | Ryuji Ueno | Agent for treating hepato-biliary diseases |
US5981607A (en) | 1998-01-20 | 1999-11-09 | Allergan | Emulsion eye drop for alleviation of dry eye related symptoms in dry eye patients and/or contact lens wearers |
CA2385732C (en) * | 1999-10-15 | 2009-02-10 | Sucampo Ag | Bicyclic compounds composition and method for stabilizing the same |
US6414016B1 (en) | 2000-09-05 | 2002-07-02 | Sucampo, A.G. | Anti-constipation composition |
JP4210631B2 (ja) | 2004-06-24 | 2009-01-21 | 株式会社日立製作所 | ブレーキ制御装置 |
-
2000
- 2000-10-13 CA CA002385732A patent/CA2385732C/en not_active Expired - Lifetime
- 2000-10-13 TW TW089121423A patent/TWI281918B/zh not_active IP Right Cessation
- 2000-10-13 AT AT00966462T patent/ATE267189T1/de active
- 2000-10-13 PT PT04005836T patent/PT1426361E/pt unknown
- 2000-10-13 RU RU2002112984A patent/RU2695274C3/ru active Protection Beyond IP Right Term
- 2000-10-13 EP EP04005836.4A patent/EP1426361B2/en not_active Expired - Lifetime
- 2000-10-13 HU HU1300369A patent/HU230484B1/hu not_active IP Right Cessation
- 2000-10-13 TR TR2002/01032T patent/TR200201032T2/xx unknown
- 2000-10-13 CN CNB008143137A patent/CN1268623C/zh not_active Ceased
- 2000-10-13 WO PCT/JP2000/007109 patent/WO2001027099A2/en active IP Right Grant
- 2000-10-13 ES ES04005836.4T patent/ES2309410T5/es not_active Expired - Lifetime
- 2000-10-13 AU AU76856/00A patent/AU780342B2/en not_active Expired
- 2000-10-13 DK DK04005836T patent/DK1426361T4/en active
- 2000-10-13 MX MXPA02003756A patent/MXPA02003756A/es active IP Right Grant
- 2000-10-13 ES ES00966462T patent/ES2221859T3/es not_active Expired - Lifetime
- 2000-10-13 AT AT04005836T patent/ATE402925T2/de active
- 2000-10-13 AR ARP000105407A patent/AR026046A1/es not_active Application Discontinuation
- 2000-10-13 PT PT00966462T patent/PT1220849E/pt unknown
- 2000-10-13 KR KR1020027004709A patent/KR100830061B1/ko active Protection Beyond IP Right Term
- 2000-10-13 IL IL14880300A patent/IL148803A0/xx active IP Right Grant
- 2000-10-13 DK DK00966462T patent/DK1220849T3/da active
- 2000-10-13 HU HU0203746A patent/HU229547B1/hu not_active IP Right Cessation
- 2000-10-13 JP JP2001530318A patent/JP4332316B2/ja not_active Expired - Lifetime
- 2000-10-13 BR BRPI0014869A patent/BRPI0014869B8/pt not_active IP Right Cessation
- 2000-10-13 EP EP00966462A patent/EP1220849B1/en not_active Expired - Lifetime
- 2000-10-13 CZ CZ20021037A patent/CZ303625B6/cs not_active IP Right Cessation
- 2000-10-13 NZ NZ518020A patent/NZ518020A/en not_active IP Right Cessation
- 2000-10-13 DE DE60039727T patent/DE60039727D1/de not_active Expired - Lifetime
- 2000-10-13 DE DE60010913T patent/DE60010913T2/de not_active Expired - Lifetime
- 2000-10-16 US US09/688,351 patent/US6583174B1/en not_active Expired - Lifetime
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2002
- 2002-03-21 IL IL148803A patent/IL148803A/en unknown
- 2002-03-22 ZA ZA200202312A patent/ZA200202312B/en unknown
- 2002-04-12 NO NO20021736A patent/NO330258B1/no not_active IP Right Cessation
- 2002-10-07 HK HK04109640.1A patent/HK1066792A1/xx not_active IP Right Cessation
- 2002-10-07 HK HK02107337.5A patent/HK1045693B/zh not_active IP Right Cessation
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2003
- 2003-03-10 US US10/383,581 patent/US7417067B2/en not_active Expired - Lifetime
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2004
- 2004-12-24 AU AU2004242503A patent/AU2004242503B2/en not_active Expired
-
2008
- 2008-06-23 US US12/144,000 patent/US8088934B2/en not_active Expired - Lifetime
-
2009
- 2009-05-25 JP JP2009125293A patent/JP2009235079A/ja active Pending
-
2011
- 2011-11-04 US US13/289,386 patent/US8097649B1/en not_active Expired - Lifetime
- 2011-12-27 US US13/337,391 patent/US20120095090A1/en not_active Abandoned
-
2013
- 2013-01-30 AR ARP130100275A patent/AR089848A2/es not_active Application Discontinuation
-
2017
- 2017-08-16 AR ARP170102288A patent/AR109354A2/es unknown
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