TR200102861T2 - Uzun zincirli trigliseridler ve lipofilik surfaktantları içeren oral farmasötik kompozisyonlar. - Google Patents

Uzun zincirli trigliseridler ve lipofilik surfaktantları içeren oral farmasötik kompozisyonlar.

Info

Publication number
TR200102861T2
TR200102861T2 TR2001/02861T TR200102861T TR200102861T2 TR 200102861 T2 TR200102861 T2 TR 200102861T2 TR 2001/02861 T TR2001/02861 T TR 2001/02861T TR 200102861 T TR200102861 T TR 200102861T TR 200102861 T2 TR200102861 T2 TR 200102861T2
Authority
TR
Turkey
Prior art keywords
long chain
pharmaceutical compositions
active ingredient
drug
compositions
Prior art date
Application number
TR2001/02861T
Other languages
English (en)
Inventor
A. Perry Elizabeth
Chandler Susan
Joan Christine Ferdinando Josephine
De Nijs Henrik
Original Assignee
R.P. Scherer Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by R.P. Scherer Corporation filed Critical R.P. Scherer Corporation
Publication of TR200102861T2 publication Critical patent/TR200102861T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Mevcut bulus; içerisinde, sivi vehikülün, 14'ten 22'ye kadar karbon atomuna sahip olan bir uzun zincirli yag asidinin bir gliseridini ve 10'dan daha az bir HLB degerine sahip bir lipofilik surfaktanti içerdigi bir sivi vehikül veya tasiyici içinde çözünen bir ilaç veya aktif muhteviyati ihtiva eden, oral yolla vermek için sivi farmasötik kompozisyonlar ile ilgilidir. Bulusun kompozisyonlari; arttirilmis ilaç veya aktif muhteviyat stabilitesini saglamaktadir ve serbest yag asitleri ile karsilastirildiginda, söz konusu ilaç veya aktif muhteviyat ile daha az reaktif olan bir sivi vehikül ihtiva etmektedirler. Bir yapilanmada, sivi farmasötik kompozisyonlar; testosteron undekanoat, uzun zincirli bir trigliserid ve lauroglikolu içermektedir. Söz konusu kompozisyonlar; oral yolla verilebilmekte ve yumusak jel veya sert kabuklu kapsül formunda formüle edilebilmektedir.
TR2001/02861T 1999-04-01 2000-03-29 Uzun zincirli trigliseridler ve lipofilik surfaktantları içeren oral farmasötik kompozisyonlar. TR200102861T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9907715.8A GB9907715D0 (en) 1999-04-01 1999-04-01 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
TR200102861T2 true TR200102861T2 (tr) 2004-12-21

Family

ID=10850947

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/02861T TR200102861T2 (tr) 1999-04-01 2000-03-29 Uzun zincirli trigliseridler ve lipofilik surfaktantları içeren oral farmasötik kompozisyonlar.

Country Status (23)

Country Link
EP (1) EP1173153B1 (tr)
JP (1) JP4636692B2 (tr)
AT (1) ATE311177T1 (tr)
AU (1) AU763971B2 (tr)
BR (1) BRPI0009373B8 (tr)
CA (1) CA2366754C (tr)
CZ (1) CZ301724B6 (tr)
DE (1) DE60024429T2 (tr)
DK (1) DK1173153T3 (tr)
ES (1) ES2251991T3 (tr)
GB (1) GB9907715D0 (tr)
HK (1) HK1040364B (tr)
HU (1) HU227155B1 (tr)
IL (2) IL145567A0 (tr)
MX (1) MXPA01009817A (tr)
NO (1) NO331396B1 (tr)
NZ (1) NZ514649A (tr)
PL (1) PL196823B1 (tr)
RU (1) RU2207859C1 (tr)
SI (1) SI1173153T1 (tr)
TR (1) TR200102861T2 (tr)
WO (1) WO2000059482A1 (tr)
ZA (1) ZA200108457B (tr)

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US20030236236A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
AUPR573001A0 (en) * 2001-06-15 2001-07-12 Glaxo Wellcome Australia Ltd Lymphatic drug delivery system
US7125568B2 (en) 2001-08-23 2006-10-24 Sung Michael T Lipophilic drug compositions
KR100533460B1 (ko) * 2002-07-20 2005-12-08 대화제약 주식회사 난용성 약물의 가용화용 점막흡착성 조성물, 이를 이용한난용성 약물의 가용화용 제형 및 이들의 제조 방법
KR100533458B1 (ko) * 2002-07-20 2005-12-07 대화제약 주식회사 파클리탁셀의 가용화용 조성물 및 그의 제조 방법
US20040191207A1 (en) * 2003-03-31 2004-09-30 Lipari John M. Alpha-hydroxy acid ester drug delivery compositions and methods of use
WO2005016312A1 (en) 2003-08-13 2005-02-24 Nobex Corporation Micro-particle fatty acid salt solid dosage formulations for therapeutic agents
EP2985026B1 (en) * 2005-04-15 2022-08-03 Clarus Therapeutics, Inc. Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same
US8492369B2 (en) 2010-04-12 2013-07-23 Clarus Therapeutics Inc Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same
CN1853728A (zh) * 2005-04-19 2006-11-01 上海天博生物科技有限公司 一种改善药物或营养物口服吸收的方法、配方及其应用
JP4889262B2 (ja) * 2005-08-19 2012-03-07 理研ビタミン株式会社 脂溶性薬剤組成物
GB0807605D0 (en) * 2008-04-28 2008-06-04 Diurnal Ltd Lipid composition
US11304960B2 (en) * 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
US9375437B2 (en) 2010-06-18 2016-06-28 Lipocine Inc. Progesterone containing oral dosage forms and kits
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
US8951996B2 (en) 2011-07-28 2015-02-10 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
IN2014MN02214A (tr) 2012-05-10 2015-07-17 Painreform Ltd
RU2632441C2 (ru) 2012-06-28 2017-10-04 МакНЕЙЛ-ППС, ИНК. Липидные композиции рацекадотрила
US9801819B2 (en) 2012-06-28 2017-10-31 Johnson & Johnson Consumer Inc. Racecadotril compositions
CA2931086C (en) * 2012-12-20 2020-11-03 Solural Pharma ApS Solid oral dosage form of testosterone derivative
US10245273B2 (en) 2013-12-26 2019-04-02 Clarus Therapeutics, Inc. Oral pharmaceutical products and methods of use combining testosterone esters with hypolipidemic agents
RU2708238C2 (ru) * 2014-06-17 2019-12-05 Мерк Шарп и Доум Б.В. Стабильные составы тестостерона ундеканоата
PT3157508T (pt) 2014-06-19 2021-02-17 Solural Pharma ApS Forma de dosagem oral sólida de compostos lipofílicos
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
WO2016033556A1 (en) 2014-08-28 2016-03-03 Lipocine Inc. BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
BR112017027688A2 (pt) 2015-06-22 2018-09-04 Lipocine Inc Composições orais que contêm éster de 17- hidroxiprogesterona e métodos relacionados
US20180147215A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy
IL274893B1 (en) 2017-11-27 2024-04-01 Umecrine Cognition Ab Pharmaceutical formulation of 3 alpha-ethynyl-3 beta-hydroxyandrostan-17-one oxime

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JPS5218811A (en) * 1975-08-01 1977-02-12 Eisai Co Ltd Preparation of aqueous solution of fat- soluble substances
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EP1189620B1 (en) * 1999-04-01 2004-06-23 Akzo Nobel N.V. Formulation comprising testosteron undecanoate and castor oil

Also Published As

Publication number Publication date
EP1173153A1 (en) 2002-01-23
PL350094A1 (en) 2002-11-04
NZ514649A (en) 2003-09-26
IL145567A (en) 2006-04-10
NO20014719D0 (no) 2001-09-28
EP1173153B1 (en) 2005-11-30
NO331396B1 (no) 2011-12-12
RU2207859C1 (ru) 2003-07-10
CZ20013460A3 (cs) 2002-06-12
GB9907715D0 (en) 1999-05-26
SI1173153T1 (sl) 2006-06-30
HK1040364A1 (en) 2002-06-07
CZ301724B6 (cs) 2010-06-02
JP2003526620A (ja) 2003-09-09
EP1173153A4 (en) 2002-01-30
HK1040364B (zh) 2006-02-10
MXPA01009817A (es) 2002-07-30
CA2366754A1 (en) 2000-10-12
RU2001129365A (ru) 2004-02-20
BRPI0009373B1 (pt) 2015-09-01
BR0009373A (pt) 2002-01-29
ES2251991T3 (es) 2006-05-16
PL196823B1 (pl) 2008-02-29
BRPI0009373B8 (pt) 2021-05-25
AU4049400A (en) 2000-10-23
DK1173153T3 (da) 2006-02-20
HU227155B1 (en) 2010-09-28
AU763971B2 (en) 2003-08-07
HUP0201444A2 (hu) 2002-11-28
ATE311177T1 (de) 2005-12-15
NO20014719L (no) 2001-10-24
HUP0201444A3 (en) 2004-05-28
JP4636692B2 (ja) 2011-02-23
DE60024429T2 (de) 2006-08-03
WO2000059482A1 (en) 2000-10-12
DE60024429D1 (de) 2006-01-05
CA2366754C (en) 2009-07-14
IL145567A0 (en) 2002-06-30
ZA200108457B (en) 2004-02-12

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