CA2309033A1 - Lacrimal gland specific emulsions for topical application to ocular tissue - Google Patents
Lacrimal gland specific emulsions for topical application to ocular tissue Download PDFInfo
- Publication number
- CA2309033A1 CA2309033A1 CA002309033A CA2309033A CA2309033A1 CA 2309033 A1 CA2309033 A1 CA 2309033A1 CA 002309033 A CA002309033 A CA 002309033A CA 2309033 A CA2309033 A CA 2309033A CA 2309033 A1 CA2309033 A1 CA 2309033A1
- Authority
- CA
- Canada
- Prior art keywords
- cyclosporin
- lacrimal gland
- topical application
- ocular tissue
- gland specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
A pharmaceutical composition is disclosed in the form of a nonirritating emulsion which includes at least one cyclosporin in admixture with a higher fatty acid glyceride and polysorbate 80. More particularly, the cyclosporin may be cyclosporin A and the higher fatty acid glyceride may be castor oil. Composition has been found to be of a high comfort level and low irritation potential suitable for delivery of medications to sensitive areas such as ocular tissues with enhanced absorption in the lacrimal gland. In addition, the composition has stability for up to nine months without crystallization of cyclosporin.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/243,279 US5474979A (en) | 1994-05-17 | 1994-05-17 | Nonirritating emulsions for sensitive tissue |
US08/243,279 | 1994-05-17 | ||
CA002190485A CA2190485C (en) | 1994-05-17 | 1995-05-17 | Lacrimal gland specific emulsions for topical application to ocular tissue |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002190485A Division CA2190485C (en) | 1994-05-17 | 1995-05-17 | Lacrimal gland specific emulsions for topical application to ocular tissue |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2309033A1 true CA2309033A1 (en) | 1995-11-23 |
CA2309033C CA2309033C (en) | 2003-08-26 |
Family
ID=25678827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002309033A Expired - Lifetime CA2309033C (en) | 1994-05-17 | 1995-05-17 | Lacrimal gland specific emulsions for topical application to ocular tissue |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2309033C (en) |
-
1995
- 1995-05-17 CA CA002309033A patent/CA2309033C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2309033C (en) | 2003-08-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20150519 |