DK0683816T3 - Fremgangsmåde til dyrkning af porcinreproduktions- og respirationssygdom-virus og dets anvendelse i vacciner - Google Patents

Fremgangsmåde til dyrkning af porcinreproduktions- og respirationssygdom-virus og dets anvendelse i vacciner

Info

Publication number
DK0683816T3
DK0683816T3 DK94907895T DK94907895T DK0683816T3 DK 0683816 T3 DK0683816 T3 DK 0683816T3 DK 94907895 T DK94907895 T DK 94907895T DK 94907895 T DK94907895 T DK 94907895T DK 0683816 T3 DK0683816 T3 DK 0683816T3
Authority
DK
Denmark
Prior art keywords
prrsv
vaccines
cultivating
disease virus
respiratory disease
Prior art date
Application number
DK94907895T
Other languages
Danish (da)
English (en)
Inventor
Thomas Sanderson
Michael J Mcginley
Jeffrey J Zimmerman
Howard T Hill
Michael C Meetz
Eugene C Pirtle
Sabrina L Swenson
George P Shibley
Original Assignee
Bayer Ag
Univ Iowa State Res Found Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Univ Iowa State Res Found Inc filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0683816T3 publication Critical patent/DK0683816T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/815—Viral vaccine for porcine species, e.g. swine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK94907895T 1993-02-08 1994-01-26 Fremgangsmåde til dyrkning af porcinreproduktions- og respirationssygdom-virus og dets anvendelse i vacciner DK0683816T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1491593A 1993-02-08 1993-02-08
PCT/US1994/000951 WO1994018311A1 (fr) 1993-02-08 1994-01-26 Procede de culture du virus du syndrome des fonctions reproductrices et respiratoires du porc et utilisation de cette culture en vaccins

Publications (1)

Publication Number Publication Date
DK0683816T3 true DK0683816T3 (da) 2001-01-08

Family

ID=21768529

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94907895T DK0683816T3 (da) 1993-02-08 1994-01-26 Fremgangsmåde til dyrkning af porcinreproduktions- og respirationssygdom-virus og dets anvendelse i vacciner

Country Status (21)

Country Link
US (2) US5510258A (fr)
EP (1) EP0683816B1 (fr)
JP (1) JP3710095B2 (fr)
KR (1) KR100374295B1 (fr)
CN (1) CN1080300C (fr)
AT (1) ATE197314T1 (fr)
AU (1) AU681874B2 (fr)
BG (1) BG63170B1 (fr)
CZ (1) CZ289743B6 (fr)
DE (1) DE69426228T2 (fr)
DK (1) DK0683816T3 (fr)
ES (1) ES2152304T3 (fr)
FI (1) FI117513B (fr)
GR (1) GR3035257T3 (fr)
HU (1) HU218430B (fr)
NO (1) NO317662B1 (fr)
NZ (1) NZ261992A (fr)
PL (1) PL178609B1 (fr)
PT (1) PT683816E (fr)
SK (1) SK98695A3 (fr)
WO (1) WO1994018311A1 (fr)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
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AU2196592A (en) 1991-06-06 1993-01-08 Stichting Centraal Diergeneeskundig Instituut Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
US5846805A (en) 1991-08-26 1998-12-08 Boehringer Ingelheim Animal Health, Inc. Culture of swine infertility and respiratory syndrome virus in simian cells
US6982160B2 (en) * 1991-08-26 2006-01-03 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions that include SIRS virus
US6042830A (en) * 1992-08-05 2000-03-28 Boehringer Ingelheim Vetmedica, Inc. Viral agent associated with mystery swine disease
US6080570A (en) * 1991-08-26 2000-06-27 Boehringer Ingelheim Vetmedica, Inc. Method of producing a vaccine for Swine Infertility and Respiratory Syndrome
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US6380376B1 (en) 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6773908B1 (en) * 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
ES2074950B1 (es) * 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.
US5690940A (en) * 1995-06-21 1997-11-25 Regents Of The University Of Minnesota Low pathogencity PRRS live virus vaccines and methods of preparation thereof
ES2102971B1 (es) * 1996-01-25 1998-03-01 Hipra Lab Sa Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion.
CA2248182C (fr) * 1996-03-01 2004-04-20 Schering Corporation Vaccin contre le syndrome dysgenesique respiratoire porcin
US6015663A (en) * 1996-03-01 2000-01-18 The United States Of America As Represented By The Secretary Of Agriculture Restriction enzyme screen for differentiating porcine reproductive and respiratory syndrome virus strains
US5866401A (en) * 1996-03-01 1999-02-02 Schering Corporation Porcine reproductive and respiratory syndrome vaccine
US5976537A (en) * 1996-07-02 1999-11-02 The United States Of America As Represented By The Secretary Of Agriculture Porcine reproductive and respiratory syndrome vaccine
PT835930E (pt) * 1996-10-09 2001-06-29 Akzo Nobel Nv Estirpes europeias de vacina do virus do sindroma reprodutivo e respiratorio porcino (prrsv)
EP0839912A1 (fr) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Clones infectieux de virus à ARN, vaccins et essais diagnostiques
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
WO1998035023A1 (fr) * 1997-02-07 1998-08-13 Origen, Inc. Procede servant a cultiver le virus du syndrome respiratoire et reproductif porcin afin de l'utiliser en tant que vaccin et dans des essais diagnostiques
KR100388257B1 (ko) 1997-05-06 2003-06-19 스티칭 디엔스트 랜드보위쿤디그 온데조에크 백신 또는 진단방법에서 사용하기 위한 피알알에스 바이러스의 피알알에스브이 항원부위 인식성 펩타이드 서열
AU8393398A (en) * 1997-07-10 1999-02-08 Regents Of The University Of Minnesota Causative agent of sow abortion and mortality syndrome (sams), vaccine compositions, antibodies and method
UA78180C2 (uk) 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
NZ501264A (en) 1998-12-22 2001-09-28 Pfizer Prod Inc Polynucleotide DNA sequence encoding an infectious RNA molecule encoding a North American PRRS
EP1157121B1 (fr) * 1999-03-08 2013-04-24 Boehringer Ingelheim Vetmedica GmbH Réplicon du virus du syndrome dysgenesique respiratoire porcin (srdp)
ES2388909T3 (es) * 1999-04-22 2012-10-19 The United States Of America, As Represented Bythe Secretary Of Agriculture Vacuna contra el virus del síndrome respiratorio y reproductivo porcino basada en aislado JA-142 aislada
US6497883B1 (en) * 1999-06-10 2002-12-24 Merial Porcine circovirus recombinant poxvirus vaccine
ES2170622B1 (es) * 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
WO2001046390A2 (fr) * 1999-12-20 2001-06-28 Agricultural Research Council Methode d'inactivation de micro-organismes
DK1255815T3 (da) * 2000-02-08 2006-10-30 Univ Minnesota Porcint reproduktivt og respiratorisk syndromvirus til fremgangsmåder til anvendelse
US6740490B2 (en) * 2001-01-29 2004-05-25 Kansas State University Research Foundation Identification and applications of porcine reproductive and respiratory syndrome virus host susceptibility factor(s) for improved swine breeding
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US7906311B2 (en) 2002-03-20 2011-03-15 Merial Limited Cotton rat lung cells for virus culture
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CN102660578B (zh) 2004-12-30 2016-12-14 勃林格殷格翰动物保健有限公司 Pcv2免疫原性组合物和产生这种组合物的方法
US7691368B2 (en) 2005-04-15 2010-04-06 Merial Limited Vaccine formulations
DK1904631T3 (da) 2005-06-24 2012-08-13 Univ Minnesota PRRS-vira, infektiøse kloner, mutanter deraf samt anvendelsesfremgangsmåder
EP2275132B1 (fr) 2005-12-29 2021-03-03 Boehringer Ingelheim Animal Health USA Inc. Composés immunogénique multivalent de PCV2 et leurs méthodes de préparation
CN100523177C (zh) * 2007-01-09 2009-08-05 中国农业科学院哈尔滨兽医研究所 猪繁殖与呼吸综合症病毒弱毒疫苗株及其应用
MX2009007457A (es) 2007-01-12 2009-08-12 Univ Illinois Celulas que no son de mono para el desarrollo del virus del sindrome porcino reproductor y respiratorio (prrs).
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CA2691755A1 (fr) * 2007-06-25 2008-12-31 South Dakota State University Virus du syndrome dysgenesique et respiratoire porcin de type 1 nord-americain recombinant et procedes d'utilisation
FI122778B (fi) 2008-03-31 2012-06-29 Metso Power Oy Pyrolyysimenetelmä kattilan yhteydessä ja pyrolyysilaitteisto
CN101363865B (zh) * 2008-05-26 2013-03-06 北京庄笛浩禾生物医学科技有限公司 一种猪蓝耳病毒胶体金检测试纸条、其制备方法及其应用
RU2561595C2 (ru) * 2008-08-25 2015-08-27 Бёрингер Ингельхайм Ветмедика, Инк. Вакцина против высокопатогенного репродуктивно-респираторного синдрома свиней (hp prrs)
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
MY157607A (en) 2009-09-10 2016-06-30 Merial Inc New vaccine formulations comprising saponin-containing adjuvants
CA2827337C (fr) 2011-02-17 2019-07-09 Boehringer Ingelheim Vetmedica Gmbh Procede de production de prrsv a l'echelon commercial
PL2959916T3 (pl) 2011-02-17 2019-05-31 Boehringer Ingelheim Vetmedica Gmbh Nowy europejski szczep prrsv
EP2737059A1 (fr) 2011-07-29 2014-06-04 Boehringer Ingelheim Vetmedica GmbH Nouveau virus srrp induisant un interféron de type i dans des cellules susceptibles
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
ES2626297T3 (es) 2011-08-12 2017-07-24 Merial, Inc. Preservación asistida por vacío de productos biológicos, en particular de vacunas
MX366051B (es) 2012-12-07 2019-06-26 Univ Illinois Composiciones del virus del síndrome reproductor y respiratorio de porcino y sus usos.
CN105073130A (zh) 2013-03-15 2015-11-18 勃林格殷格翰动物保健公司 猪生殖与呼吸综合征病毒、组合物、疫苗及使用方法
RU2662685C2 (ru) 2013-09-25 2018-07-26 Зоэтис Сервисиз Ллс Pcv2b дивергентная вакцинная композиция и способы её применения
TWI745278B (zh) 2014-10-10 2021-11-11 以色列商艾畢克生物實驗有限公司 發泡性降低之疫苗組合物
CN104694485A (zh) * 2015-02-13 2015-06-10 广西壮族自治区兽医研究所 Z-ietd-fmk在提高prrsv体外培养滴度方面的应用及其方法
JP7018941B2 (ja) 2016-06-17 2022-02-14 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 直鎖または分枝ポリアクリル酸ポリマーアジュバントを含む新規な免疫原性処方物

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US5213795A (en) * 1990-10-24 1993-05-25 Oxford Encephalomyocarditis virus vaccine
AU2196592A (en) * 1991-06-06 1993-01-08 Stichting Centraal Diergeneeskundig Instituut Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
CA2116348C (fr) * 1991-08-26 2001-07-03 James E. Collins Vaccin sirs et methode de diagnostic
KR0138092B1 (ko) * 1991-08-26 1998-04-30 제임스 씨. 데세사레 미확인(Mystery) 돼지 질병 관련 바이러스제
AU2696792A (en) * 1991-09-16 1993-04-27 David A Benfield Vaccine for mystery swine disease and method for diagnosis thereof
EP0610250B2 (fr) * 1991-10-14 2008-10-29 Intervet International BV Vaccin et diagnostic pour le syndrome respiratoire reproductif porcin (prrs)
FR2682966B1 (fr) * 1991-10-29 1994-12-02 Rhone Merieux Preparation d'antigenes et de vaccins du virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie.
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome

Also Published As

Publication number Publication date
CN1117742A (zh) 1996-02-28
SK98695A3 (en) 1996-11-06
WO1994018311A1 (fr) 1994-08-18
FI117513B (fi) 2006-11-15
EP0683816B1 (fr) 2000-11-02
CZ203195A3 (en) 1995-12-13
PL178609B1 (pl) 2000-05-31
CZ289743B6 (cs) 2002-03-13
BG63170B1 (bg) 2001-05-31
PT683816E (pt) 2001-03-30
NO317662B1 (no) 2004-11-29
NO953091L (no) 1995-08-07
AU681874B2 (en) 1997-09-11
NO953091D0 (no) 1995-08-07
DE69426228T2 (de) 2001-03-01
HUT72917A (en) 1996-06-28
FI953731A (fi) 1995-08-04
CN1080300C (zh) 2002-03-06
JPH08506486A (ja) 1996-07-16
ATE197314T1 (de) 2000-11-15
AU6128594A (en) 1994-08-29
NZ261992A (en) 1996-06-25
EP0683816A1 (fr) 1995-11-29
US5587164A (en) 1996-12-24
BG99850A (bg) 1996-02-28
HU9502330D0 (en) 1996-05-28
GR3035257T3 (en) 2001-04-30
PL310126A1 (en) 1995-11-27
US5510258A (en) 1996-04-23
DE69426228D1 (de) 2000-12-07
KR100374295B1 (ko) 2003-12-24
FI953731A0 (fi) 1995-08-04
HU218430B (hu) 2000-08-28
ES2152304T3 (es) 2001-02-01
JP3710095B2 (ja) 2005-10-26

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