CA2248182C - Vaccin contre le syndrome dysgenesique respiratoire porcin - Google Patents

Vaccin contre le syndrome dysgenesique respiratoire porcin Download PDF

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Publication number
CA2248182C
CA2248182C CA002248182A CA2248182A CA2248182C CA 2248182 C CA2248182 C CA 2248182C CA 002248182 A CA002248182 A CA 002248182A CA 2248182 A CA2248182 A CA 2248182A CA 2248182 C CA2248182 C CA 2248182C
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CA
Canada
Prior art keywords
virus
vaccine
prrs
neb
respiratory syndrome
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Expired - Lifetime
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CA002248182A
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English (en)
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CA2248182A1 (fr
Inventor
Richard A. Hesse
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Merck Sharp and Dohme LLC
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Schering Corp
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Application filed by Schering Corp filed Critical Schering Corp
Publication of CA2248182A1 publication Critical patent/CA2248182A1/fr
Application granted granted Critical
Publication of CA2248182C publication Critical patent/CA2248182C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)

Abstract

L'invention concerne un vaccin contre le syndrome dysgénésique respiratoire porcin (PRRS), ainsi que des procédés de traitement de ce syndrome. Le vaccin est dérivé de l'agent viral NEB-1-P94, déposé sous le numéro VR-2525 auprès de l'"American Type Culture Collection". En outre, l'invention porte sur un virus vaccinal possédant des caractéristiques phénotypiques distinctes de celles du virus du PRRS de type sauvage.
CA002248182A 1996-03-01 1997-02-26 Vaccin contre le syndrome dysgenesique respiratoire porcin Expired - Lifetime CA2248182C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60980696A 1996-03-01 1996-03-01
US08/609,806 1996-03-01
PCT/US1997/002562 WO1997031651A1 (fr) 1996-03-01 1997-02-26 Vaccin contre le syndrome dysgenesique respiratoire porcin

Publications (2)

Publication Number Publication Date
CA2248182A1 CA2248182A1 (fr) 1997-09-04
CA2248182C true CA2248182C (fr) 2004-04-20

Family

ID=24442410

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002248182A Expired - Lifetime CA2248182C (fr) 1996-03-01 1997-02-26 Vaccin contre le syndrome dysgenesique respiratoire porcin

Country Status (19)

Country Link
EP (1) EP0894007A1 (fr)
JP (1) JP3135069B2 (fr)
KR (1) KR100297537B1 (fr)
CN (1) CN1165342C (fr)
AR (1) AR006023A1 (fr)
AU (1) AU2277497A (fr)
BG (1) BG64693B1 (fr)
BR (1) BR9708443B1 (fr)
CA (1) CA2248182C (fr)
CO (1) CO4600644A1 (fr)
CZ (1) CZ273798A3 (fr)
EE (1) EE04741B1 (fr)
HU (1) HUP9901958A3 (fr)
MY (1) MY115070A (fr)
PL (1) PL328627A1 (fr)
RU (1) RU2187333C2 (fr)
SK (1) SK119498A3 (fr)
WO (1) WO1997031651A1 (fr)
ZA (1) ZA971663B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000053787A1 (fr) 1999-03-08 2000-09-14 Id-Lelystad, Instituut Voor Dierhouderij En Dierg Ezondheid B.V. Vaccins contre le virus du syndrome dysgenesique respiratoire porcin (srdp)
EP0839912A1 (fr) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Clones infectieux de virus à ARN, vaccins et essais diagnostiques
CA2440933A1 (fr) 1998-12-22 2000-06-22 Pfizer Products Inc. Un clone d'adnc infectieux du virus nord-americain du syndrome dysgenesique respiratoire porcin (sdrp) et ses utilisations
JP4778620B2 (ja) 1999-04-22 2011-09-21 ユナイテッド ステイツ デパートメント オブ アグリカルチャー 分離株ｊａ−１４２に基づく、豚繁殖・呼吸障害症候群ワクチン
KR20070028547A (ko) 2004-06-18 2007-03-12 리전츠 오브 더 유니버스티 오브 미네소타 바이러스에 감염되고 백신접종된 생물의 동정
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
UA95778C2 (ru) 2005-06-24 2011-09-12 Риджентс Оф Зе Юниверсити Оф Миннесота Вирусы репродуктивно-респираторного синдрома свиней, их инфекционные клоны и мутанты и способы применения
CN101612395B (zh) * 2008-06-24 2012-02-08 扬州优邦生物制药有限公司 一种培养敏感细胞生产蓝耳病疫苗的方法
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
KR102183276B1 (ko) 2011-02-17 2020-11-26 베링거잉겔하임베트메디카게엠베하 신규 유럽형 ｐｒｒｓｖ 스트레인
KR101983980B1 (ko) 2011-02-17 2019-05-30 베링거잉겔하임베트메디카게엠베하 Ｐｒｒｓｖ의 상업적 규모의 제조 방법
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
EP2737058A1 (fr) 2011-07-29 2014-06-04 Boehringer Ingelheim Vetmedica GmbH Clone d'adnc infectieux du virus srrp européen et ses utilisations
KR101300528B1 (ko) * 2011-10-05 2013-09-02 캔 테크놀로지스 인코포레이티드 액티노바실러스 플루로뉴모니애 감염 방지 및 처치용 조성물
CN105073130A (zh) 2013-03-15 2015-11-18 勃林格殷格翰动物保健公司 猪生殖与呼吸综合征病毒、组合物、疫苗及使用方法
EP4012025A1 (fr) * 2020-12-10 2022-06-15 Univerzita Palackého v Olomouci Milieu de transport pour les échantillons contenant des acides nucléiques et/ou des protéines
CZ309704B6 (cs) * 2020-12-10 2023-08-09 Univerzita Palackého v Olomouci Transportní médium pro transport a skladování virů

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6042830A (en) * 1992-08-05 2000-03-28 Boehringer Ingelheim Vetmedica, Inc. Viral agent associated with mystery swine disease
EP0610250B2 (fr) * 1991-10-14 2008-10-29 Intervet International BV Vaccin et diagnostic pour le syndrome respiratoire reproductif porcin (prrs)
FR2686097B1 (fr) * 1992-01-14 1994-12-30 Rhone Merieux Preparation d'antigenes et de vaccins de virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie.
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
DE69426228T2 (de) * 1993-02-08 2001-03-01 Bayer Ag Verfahren zum Vermehren des das Reproduktions- und Atemwegs-Syndrom verursachenden Schweinevirus und dessen Verwendung als Impfstoff.
ES2074950B1 (es) * 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.
PT676467E (pt) * 1994-04-11 2002-02-28 Akzo Nobel Nv Estirpes europeias de vacina do virus do sindroma reprodutivo e respiratorio porcino (prrsv)
US5690940A (en) * 1995-06-21 1997-11-25 Regents Of The University Of Minnesota Low pathogencity PRRS live virus vaccines and methods of preparation thereof

Also Published As

Publication number Publication date
CO4600644A1 (es) 1998-05-08
BR9708443B1 (pt) 2012-06-12
CN1216922A (zh) 1999-05-19
SK119498A3 (en) 1999-07-12
PL328627A1 (en) 1999-02-15
HUP9901958A3 (en) 2000-04-28
KR100297537B1 (ko) 2001-10-26
CN1165342C (zh) 2004-09-08
CA2248182A1 (fr) 1997-09-04
BG64693B1 (bg) 2005-12-30
HUP9901958A2 (hu) 1999-10-28
JP3135069B2 (ja) 2001-02-13
EE9800267A (et) 1999-02-15
AU2277497A (en) 1997-09-16
ZA971663B (en) 1997-08-26
CZ273798A3 (cs) 1999-02-17
EP0894007A1 (fr) 1999-02-03
WO1997031651A1 (fr) 1997-09-04
BR9708443A (pt) 1999-08-03
RU2187333C2 (ru) 2002-08-20
MX9807083A (es) 1998-12-31
BG102809A (en) 1999-05-31
JPH11506122A (ja) 1999-06-02
EE04741B1 (et) 2006-12-15
KR19990087432A (ko) 1999-12-27
AR006023A1 (es) 1999-07-21
MY115070A (en) 2003-03-31

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Effective date: 20170227