CO4600644A1 - Vacuna contra el sindrome reproductivo y respiratorio porcino - Google Patents

Vacuna contra el sindrome reproductivo y respiratorio porcino

Info

Publication number
CO4600644A1
CO4600644A1 CO97010338A CO97010338A CO4600644A1 CO 4600644 A1 CO4600644 A1 CO 4600644A1 CO 97010338 A CO97010338 A CO 97010338A CO 97010338 A CO97010338 A CO 97010338A CO 4600644 A1 CO4600644 A1 CO 4600644A1
Authority
CO
Colombia
Prior art keywords
vaccine
virus
attenuated
respiratory syndrome
live
Prior art date
Application number
CO97010338A
Other languages
English (en)
Inventor
Richard A Hesse
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24442410&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO4600644(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of CO4600644A1 publication Critical patent/CO4600644A1/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)

Abstract

La invención describe una vacuna y métodos para eltratamiento del síndrome reproductivo y respiratorio porcino. La vacuna se obtiene del agente viral NEB- 1-P94. Además, la invención describe un virus de vacuna con características fenotípicas que pueden distinguirse del virus de PRRS de tipo cimarrón. Depósito en la Asociación Americana de Cultivos Tipo No. VR-2525.La vacuna de acuerdo con la reivindicación 1 que se encuentra en forma viva, muerta o viva modificada (atenuada).La vacuna de acuerdo con a reivindicación 2 en la cual el agente viral es vivo modificado (atenuado) o se encuentra en forma líquida, congelada o desecada.La vacuna de acuerdo con la reivindicación 1 que contiene una cantidad de 104,0 a 109,0 TCID50 del virus de PRRS por ml.La vacuna de acuerdo con la reivindicación 1 en la cual el virus atenuado se puede distinguir de las formas de tipo cimarrón del virus en base a la falta de reactividad con el anticuerpo monoclonal SDOW17 y la falta de desarrollo eficiente en células macrófagos alveolares porcinas.Un método para proteger a un cerdo de la enfermedad clínica provocada por el virus del síndrome reproductivo y respiratorio porcino que comprende administrar una cantidad eficaz de la vacuna de la reivindicación 1 a un cerdo que necesita protección contra a enfermedad provocada por dicho virus.Un método de acuerdo con la reivindicación 6 en el cual dicha vacuna es administrada por vía oral, intranasal, intramuscular, intradérmica, intravenosa o subcutánea.
CO97010338A 1996-03-01 1997-02-26 Vacuna contra el sindrome reproductivo y respiratorio porcino CO4600644A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60980696A 1996-03-01 1996-03-01

Publications (1)

Publication Number Publication Date
CO4600644A1 true CO4600644A1 (es) 1998-05-08

Family

ID=24442410

Family Applications (1)

Application Number Title Priority Date Filing Date
CO97010338A CO4600644A1 (es) 1996-03-01 1997-02-26 Vacuna contra el sindrome reproductivo y respiratorio porcino

Country Status (19)

Country Link
EP (1) EP0894007A1 (es)
JP (1) JP3135069B2 (es)
KR (1) KR100297537B1 (es)
CN (1) CN1165342C (es)
AR (1) AR006023A1 (es)
AU (1) AU2277497A (es)
BG (1) BG64693B1 (es)
BR (1) BR9708443B1 (es)
CA (1) CA2248182C (es)
CO (1) CO4600644A1 (es)
CZ (1) CZ273798A3 (es)
EE (1) EE04741B1 (es)
HU (1) HUP9901958A3 (es)
MY (1) MY115070A (es)
PL (1) PL328627A1 (es)
RU (1) RU2187333C2 (es)
SK (1) SK119498A3 (es)
WO (1) WO1997031651A1 (es)
ZA (1) ZA971663B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839912A1 (en) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
CA2290220C (en) 1998-12-22 2013-11-19 Pfizer Products Inc. An infectious cdna clone of north american porcine reproductive and respiratory syndrome (prrs) virus and uses thereof
CA2366072C (en) 1999-03-08 2007-07-10 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Prrsv vaccines
JP4778620B2 (ja) 1999-04-22 2011-09-21 ユナイテッド ステイツ デパートメント オブ アグリカルチャー 分離株ｊａ−１４２に基づく、豚繁殖・呼吸障害症候群ワクチン
RU2007101725A (ru) 2004-06-18 2008-07-27 Риджентс Оф Дзе Юниверсити Оф Миннесота (Us) Идентификация инфицированных вирусом и вакцинированных вирусом организмов
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
DK2369001T3 (en) 2005-06-24 2016-10-24 Univ Minnesota PRRS viruses, infectious clones, mutants thereof and methods of use
CN101612395B (zh) * 2008-06-24 2012-02-08 扬州优邦生物制药有限公司 一种培养敏感细胞生产蓝耳病疫苗的方法
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
CA2827337C (en) 2011-02-17 2019-07-09 Boehringer Ingelheim Vetmedica Gmbh Commercial scale process for production of prrsv
BR112013021076B1 (pt) 2011-02-17 2022-11-29 Boehringer Ingelheim Vetmedica Gmbh Vírus da síndrome respiratória e reprodutiva suína (prrsv) de um tipo europeu, seu uso, vacina, método para a preparação destes
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
WO2013017568A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
KR101300528B1 (ko) * 2011-10-05 2013-09-02 캔 테크놀로지스 인코포레이티드 액티노바실러스 플루로뉴모니애 감염 방지 및 처치용 조성물
US9579373B2 (en) 2013-03-15 2017-02-28 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
EP4012025A1 (en) * 2020-12-10 2022-06-15 Univerzita Palackého v Olomouci Transport medium for samples containing nucleic acids and/or proteins
CZ309704B6 (cs) * 2020-12-10 2023-08-09 Univerzita Palackého v Olomouci Transportní médium pro transport a skladování virů

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6042830A (en) * 1992-08-05 2000-03-28 Boehringer Ingelheim Vetmedica, Inc. Viral agent associated with mystery swine disease
DE69206631T2 (de) * 1991-10-14 1996-05-15 Akzo Nobel Nv Impfstoff gegen das Fortpflanzungs- und Atmungssyndrom bei Schweinen (PRRS) und Diagnose.
FR2686097B1 (fr) * 1992-01-14 1994-12-30 Rhone Merieux Preparation d'antigenes et de vaccins de virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie.
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
CZ289743B6 (cs) * 1993-02-08 2002-03-13 Bayer Corporation Izolát viru vepřového reprodukčního a respiračního syndromu PRRSV, způsob kultivace PRRSV, tkáňová kultura, způsob přípravy vakcíny a vakcína obsahující PRRSV izolát
ES2074950B1 (es) * 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.
ATE206455T1 (de) * 1994-04-11 2001-10-15 Akzo Nobel Nv Europäische vakzinstämme des fortplanzungs- atmungs-syndromsvirus des schweins
US5690940A (en) * 1995-06-21 1997-11-25 Regents Of The University Of Minnesota Low pathogencity PRRS live virus vaccines and methods of preparation thereof

Also Published As

Publication number Publication date
CN1216922A (zh) 1999-05-19
MY115070A (en) 2003-03-31
HUP9901958A2 (hu) 1999-10-28
BG64693B1 (bg) 2005-12-30
CA2248182A1 (en) 1997-09-04
JPH11506122A (ja) 1999-06-02
AU2277497A (en) 1997-09-16
ZA971663B (en) 1997-08-26
JP3135069B2 (ja) 2001-02-13
RU2187333C2 (ru) 2002-08-20
KR19990087432A (ko) 1999-12-27
AR006023A1 (es) 1999-07-21
CZ273798A3 (cs) 1999-02-17
KR100297537B1 (ko) 2001-10-26
EE9800267A (et) 1999-02-15
CN1165342C (zh) 2004-09-08
WO1997031651A1 (en) 1997-09-04
BR9708443B1 (pt) 2012-06-12
CA2248182C (en) 2004-04-20
HUP9901958A3 (en) 2000-04-28
MX9807083A (es) 1998-12-31
PL328627A1 (en) 1999-02-15
SK119498A3 (en) 1999-07-12
EP0894007A1 (en) 1999-02-03
BG102809A (en) 1999-05-31
EE04741B1 (et) 2006-12-15
BR9708443A (pt) 1999-08-03

Similar Documents

Publication Publication Date Title
CO4600644A1 (es) Vacuna contra el sindrome reproductivo y respiratorio porcino
ES2165405T3 (es) Cepas de vacuna europeas del virus del sindrome reproductor y respiratorio porcino (prrsv).
DE60045668D1 (de) Influenzavirus-Impfstoffzusammensetzung
MXPA02011545A (es) Virus del sindrome respiratorio y reproductor porcino (peesv), vacuna recombinante para el virus de la viruela.
BRPI9911870B8 (pt) vacina de parvovírus e circovírus de suíno
ES2170234T3 (es) Vacuna contra el virus prrs (sindrome reproductor y respiratorio porcino).
WO2005021707A3 (en) Severe acute respiratory syndrome dna vaccine compositions and methods of use
ATE199022T1 (de) Europäische vakzinstämme des fortplanzungs- atmungs-syndromsvirus des sweins (prrsv)
ES2118815T3 (es) Virus de la seudorrabia, s-prv-155, atenuado y obtenido por ingenieria genetica y sus usos.
NO20082472L (no) Vaksinesammensetninger omfattende en saponin adjuvant
CO4980846A1 (es) Una composicion farmaceutica utilizada en un metodo para la prevencion y tratamiento de la enfermedad amiloidogenica
AR057695A1 (es) Procedimientos de administracion de vacunas contra calcivirus felinos, y tratamientos para inmunizar animales contra parvovirus felino y herpes virus felino
RU2001101426A (ru) Аттенуированные вирусы с минус-цепью с измененной антагонистической в отношении интерферона активностью для применения в качестве вакцин и фармацевтических веществ
RU2010117614A (ru) Авирулентная адъювантная живая вакцина против mycoplasma hyopneumoniae
EA200300023A1 (ru) 3'-ПРОЛЕКАРСТВА 2'-ДЕЗОКСИ-β-L-НУКЛЕОЗИДОВ
RU98118186A (ru) Вакцина против репродуктивного и респираторного синдрома у свиней
ECSP024257A (es) Proteinas antigenas del virus de la enfermedad de la mancha blanca en el camaron y usos de las mismas
ATE516034T1 (de) Verfahren zur modulation der immunreaktion in einem infektierten säugetier mittels transmukosales eingeben eines modulationsmittel
ES2050435T3 (es) Una preparacion medicinal o vacuna y composicion inmunogenica peptida, un metodo de inmunizacion de un mamifero contra lhrh, y un metodo para mejorar la calidad carnica del ganado porcuno.
CO2021005066A2 (es) Vacuna de ibv 4/91 con proteína espicular heteróloga
Lee et al. Newly emerging human coronaviruses: animal models and vaccine research for SARS, MERS, and COVID-19
JP2023098935A5 (es)
MA28035A1 (fr) Vaccin
JP2002534481A5 (es)
AR054259A1 (es) Vacuna contra virus de papiloma humano (hpv)