DE69426228T2 - Verfahren zum Vermehren des das Reproduktions- und Atemwegs-Syndrom verursachenden Schweinevirus und dessen Verwendung als Impfstoff. - Google Patents

Verfahren zum Vermehren des das Reproduktions- und Atemwegs-Syndrom verursachenden Schweinevirus und dessen Verwendung als Impfstoff.

Info

Publication number
DE69426228T2
DE69426228T2 DE69426228T DE69426228T DE69426228T2 DE 69426228 T2 DE69426228 T2 DE 69426228T2 DE 69426228 T DE69426228 T DE 69426228T DE 69426228 T DE69426228 T DE 69426228T DE 69426228 T2 DE69426228 T2 DE 69426228T2
Authority
DE
Germany
Prior art keywords
prrsv
vaccine
propagating
respiratory syndrome
virus causing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69426228T
Other languages
English (en)
Other versions
DE69426228D1 (de
Inventor
Thomas Sanderson
J Mcginley
J Zimmerman
T Hill
C Meetz
C Pirtle
L Swenson
P Shibley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
University of Iowa Research Foundation UIRF
Bayer Corp
Iowa State University Research Foundation ISURF
Original Assignee
Bayer AG
University of Iowa Research Foundation UIRF
Bayer Corp
Iowa State University Research Foundation ISURF
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, University of Iowa Research Foundation UIRF, Bayer Corp, Iowa State University Research Foundation ISURF filed Critical Bayer AG
Application granted granted Critical
Publication of DE69426228D1 publication Critical patent/DE69426228D1/de
Publication of DE69426228T2 publication Critical patent/DE69426228T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/815—Viral vaccine for porcine species, e.g. swine
DE69426228T 1993-02-08 1994-01-26 Verfahren zum Vermehren des das Reproduktions- und Atemwegs-Syndrom verursachenden Schweinevirus und dessen Verwendung als Impfstoff. Expired - Fee Related DE69426228T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1491593A 1993-02-08 1993-02-08
PCT/US1994/000951 WO1994018311A1 (en) 1993-02-08 1994-01-26 Process for growing porcine reproductive and respiratory syndrome virus and its use in vaccines

Publications (2)

Publication Number Publication Date
DE69426228D1 DE69426228D1 (de) 2000-12-07
DE69426228T2 true DE69426228T2 (de) 2001-03-01

Family

ID=21768529

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69426228T Expired - Fee Related DE69426228T2 (de) 1993-02-08 1994-01-26 Verfahren zum Vermehren des das Reproduktions- und Atemwegs-Syndrom verursachenden Schweinevirus und dessen Verwendung als Impfstoff.

Country Status (21)

Country Link
US (2) US5510258A (de)
EP (1) EP0683816B1 (de)
JP (1) JP3710095B2 (de)
KR (1) KR100374295B1 (de)
CN (1) CN1080300C (de)
AT (1) ATE197314T1 (de)
AU (1) AU681874B2 (de)
BG (1) BG63170B1 (de)
CZ (1) CZ289743B6 (de)
DE (1) DE69426228T2 (de)
DK (1) DK0683816T3 (de)
ES (1) ES2152304T3 (de)
FI (1) FI117513B (de)
GR (1) GR3035257T3 (de)
HU (1) HU218430B (de)
NO (1) NO317662B1 (de)
NZ (1) NZ261992A (de)
PL (1) PL178609B1 (de)
PT (1) PT683816E (de)
SK (1) SK98695A3 (de)
WO (1) WO1994018311A1 (de)

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US5690940A (en) * 1995-06-21 1997-11-25 Regents Of The University Of Minnesota Low pathogencity PRRS live virus vaccines and methods of preparation thereof
ES2102971B1 (es) * 1996-01-25 1998-03-01 Hipra Lab Sa Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion.
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US5976537A (en) * 1996-07-02 1999-11-02 The United States Of America As Represented By The Secretary Of Agriculture Porcine reproductive and respiratory syndrome vaccine
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EP0839912A1 (de) 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Ansteckende Klone von RNA-Viren und darauf basierende Impfstoffe und diagnostisches Verfahren
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WO1999002184A1 (en) * 1997-07-10 1999-01-21 Regents Of The University Of Minnesota Causative agent of sow abortion and mortality syndrome (sams), vaccine compositions, antibodies and method
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FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
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US6740490B2 (en) * 2001-01-29 2004-05-25 Kansas State University Research Foundation Identification and applications of porcine reproductive and respiratory syndrome virus host susceptibility factor(s) for improved swine breeding
US6841364B2 (en) 2002-01-22 2005-01-11 Protatek International, Inc. Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof
US7906311B2 (en) 2002-03-20 2011-03-15 Merial Limited Cotton rat lung cells for virus culture
KR20070028547A (ko) 2004-06-18 2007-03-12 리전츠 오브 더 유니버스티 오브 미네소타 바이러스에 감염되고 백신접종된 생물의 동정
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
CN103285387B (zh) 2004-12-30 2017-07-25 勃林格殷格翰动物保健有限公司 Pcv2免疫原性组合物和产生这种组合物的方法
US7691368B2 (en) 2005-04-15 2010-04-06 Merial Limited Vaccine formulations
CA2894069C (en) 2005-06-24 2019-02-26 Regents Of The University Of Minnesota Prrs viruses, infectious clones, mutants thereof, and methods of use
EP3320919B1 (de) 2005-12-29 2020-05-27 Boehringer Ingelheim Animal Health USA Inc. Multivalente immunogene pcv2-zusammensetzungen und verfahren zur herstellung solcher zusammensetzungen
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Also Published As

Publication number Publication date
JPH08506486A (ja) 1996-07-16
US5587164A (en) 1996-12-24
FI953731A0 (fi) 1995-08-04
NO953091D0 (no) 1995-08-07
NO953091L (no) 1995-08-07
FI953731A (fi) 1995-08-04
GR3035257T3 (en) 2001-04-30
CN1080300C (zh) 2002-03-06
SK98695A3 (en) 1996-11-06
AU681874B2 (en) 1997-09-11
BG63170B1 (bg) 2001-05-31
PT683816E (pt) 2001-03-30
US5510258A (en) 1996-04-23
PL178609B1 (pl) 2000-05-31
WO1994018311A1 (en) 1994-08-18
AU6128594A (en) 1994-08-29
DK0683816T3 (da) 2001-01-08
EP0683816B1 (de) 2000-11-02
CZ289743B6 (cs) 2002-03-13
PL310126A1 (en) 1995-11-27
KR100374295B1 (ko) 2003-12-24
ES2152304T3 (es) 2001-02-01
ATE197314T1 (de) 2000-11-15
DE69426228D1 (de) 2000-12-07
HU9502330D0 (en) 1996-05-28
FI117513B (fi) 2006-11-15
JP3710095B2 (ja) 2005-10-26
CN1117742A (zh) 1996-02-28
CZ203195A3 (en) 1995-12-13
HU218430B (hu) 2000-08-28
NZ261992A (en) 1996-06-25
BG99850A (bg) 1996-02-28
EP0683816A1 (de) 1995-11-29
NO317662B1 (no) 2004-11-29
HUT72917A (en) 1996-06-28

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