DE69834430D1 - Purin-derivate zur behandlung allgischer erkrankungen und systemischem lupus erythematodes - Google Patents

Purin-derivate zur behandlung allgischer erkrankungen und systemischem lupus erythematodes

Info

Publication number
DE69834430D1
DE69834430D1 DE69834430T DE69834430T DE69834430D1 DE 69834430 D1 DE69834430 D1 DE 69834430D1 DE 69834430 T DE69834430 T DE 69834430T DE 69834430 T DE69834430 T DE 69834430T DE 69834430 D1 DE69834430 D1 DE 69834430D1
Authority
DE
Germany
Prior art keywords
substituted
hydrocarbon group
directly bound
purine
allgic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69834430T
Other languages
English (en)
Other versions
DE69834430T2 (de
Inventor
Yoshiaki Isobe
Haruhisa Ogita
Masanori Tobe
Haruo Takaku
Hiroyuki Matsui
Hideyuki Tomizawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Dainippon Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Dainippon Pharma Co Ltd filed Critical Sumitomo Dainippon Pharma Co Ltd
Publication of DE69834430D1 publication Critical patent/DE69834430D1/de
Application granted granted Critical
Publication of DE69834430T2 publication Critical patent/DE69834430T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
DE69834430T 1997-12-22 1998-12-21 Purin-Derivate zur Behandlung allergischer Erkrankungen und systemischem Lupus erythematodes Expired - Lifetime DE69834430T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP35346297 1997-12-22
JP35346297 1997-12-22
PCT/JP1998/005779 WO1999032122A1 (fr) 1997-12-22 1998-12-21 Suppresseurs de la reponse immunitaire selectifs par rapport aux lymphocytes t auxiliaires de type 2

Publications (2)

Publication Number Publication Date
DE69834430D1 true DE69834430D1 (de) 2006-06-08
DE69834430T2 DE69834430T2 (de) 2007-04-19

Family

ID=18431019

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69834430T Expired - Lifetime DE69834430T2 (de) 1997-12-22 1998-12-21 Purin-Derivate zur Behandlung allergischer Erkrankungen und systemischem Lupus erythematodes

Country Status (11)

Country Link
US (1) US6376501B1 (de)
EP (1) EP1043021B1 (de)
JP (1) JP4390387B2 (de)
AT (1) ATE324895T1 (de)
AU (1) AU740321B2 (de)
CA (1) CA2315733C (de)
DE (1) DE69834430T2 (de)
NZ (1) NZ505297A (de)
TW (1) TW572758B (de)
WO (1) WO1999032122A1 (de)
ZA (1) ZA9811778B (de)

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