DE69832712T2 - Analgetische zusammensetzung enthaltend antiepileptische arzneistoffe und deren verwendungen - Google Patents

Analgetische zusammensetzung enthaltend antiepileptische arzneistoffe und deren verwendungen Download PDF

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Publication number
DE69832712T2
DE69832712T2 DE69832712T DE69832712T DE69832712T2 DE 69832712 T2 DE69832712 T2 DE 69832712T2 DE 69832712 T DE69832712 T DE 69832712T DE 69832712 T DE69832712 T DE 69832712T DE 69832712 T2 DE69832712 T2 DE 69832712T2
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DE
Germany
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combination according
combination
compound
effective amount
nsaid
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69832712T
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German (de)
English (en)
Other versions
DE69832712D1 (de
Inventor
Leslie Magnus-Miller
A. Douglas SALTEL
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Warner Lambert Co LLC
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Warner Lambert Co LLC
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Publication of DE69832712D1 publication Critical patent/DE69832712D1/de
Publication of DE69832712T2 publication Critical patent/DE69832712T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
DE69832712T 1997-09-08 1998-08-18 Analgetische zusammensetzung enthaltend antiepileptische arzneistoffe und deren verwendungen Expired - Fee Related DE69832712T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5820797P 1997-09-08 1997-09-08
US58207P 1997-09-08
PCT/US1998/017083 WO1999012537A1 (en) 1997-09-08 1998-08-18 Analgesic compositions comprising anti-epileptic compounds and methods of using same

Publications (2)

Publication Number Publication Date
DE69832712D1 DE69832712D1 (de) 2006-01-12
DE69832712T2 true DE69832712T2 (de) 2006-06-22

Family

ID=22015361

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69832712T Expired - Fee Related DE69832712T2 (de) 1997-09-08 1998-08-18 Analgetische zusammensetzung enthaltend antiepileptische arzneistoffe und deren verwendungen

Country Status (20)

Country Link
US (3) US6593368B2 (enExample)
EP (1) EP1011658B1 (enExample)
JP (1) JP3782935B2 (enExample)
KR (1) KR100537707B1 (enExample)
AT (1) ATE311867T1 (enExample)
AU (1) AU750578B2 (enExample)
BR (1) BR9812162A (enExample)
CA (1) CA2296336C (enExample)
CU (1) CU23226B7 (enExample)
DE (1) DE69832712T2 (enExample)
DK (1) DK1011658T3 (enExample)
ES (1) ES2253825T3 (enExample)
HU (1) HU226165B1 (enExample)
IL (2) IL134165A0 (enExample)
IS (1) IS5362A (enExample)
NO (1) NO324122B1 (enExample)
NZ (1) NZ502671A (enExample)
PL (1) PL339142A1 (enExample)
WO (1) WO1999012537A1 (enExample)
ZA (1) ZA988159B (enExample)

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US6451857B1 (en) 1999-03-10 2002-09-17 Warner-Lambert Company Analgesic compositions comprising anti-epileptic compounds and methods of using same
CA2370030C (en) 1999-04-09 2007-08-14 Euro-Celtique S.A. Sodium channel blocker compositions and the use thereof
AU5824800A (en) * 1999-06-23 2001-01-31 Warner-Lambert Company Use of fosphenytoin for the treatment of acute neuropathic pain
EA006598B1 (ru) * 1999-08-20 2006-02-24 Орто-Макнейл Фармасьютикал, Инк. Композиция, содержащая трамадол и противосудорожное лекарственное средство
JP4350508B2 (ja) * 2001-09-03 2009-10-21 ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー ガバペンチンまたはその類似体とα−アミノアミドとを含む薬剤組成物およびその鎮痛用途
US7612112B2 (en) 2001-10-25 2009-11-03 Depomed, Inc. Methods of treatment using a gastric retained gabapentin dosage
US20070184104A1 (en) * 2001-10-25 2007-08-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
TWI312285B (en) * 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
US20060159743A1 (en) * 2001-10-25 2006-07-20 Depomed, Inc. Methods of treating non-nociceptive pain states with gastric retentive gabapentin
US6730667B2 (en) * 2001-11-26 2004-05-04 William R. Deagle Iontophoresis disc pain blocker
JP4428053B2 (ja) 2002-02-05 2010-03-10 味の素株式会社 ガバペンチン若しくはプレガバリンおよびn型カルシウムチャンネル拮抗剤を含有する医薬組成物
WO2003070237A1 (en) * 2002-02-22 2003-08-28 Warner-Lambert Company Llc Combinations of an alpha-2-delta ligand with a selective inhibitor of cyclooxygenase-2
DK1572173T3 (da) * 2002-12-13 2010-06-14 Warner Lambert Co Alpha-2-delta-ligand til behandling af symptomer i den nedre urinvej
FR2862875B1 (fr) * 2003-12-02 2006-04-07 Mathey Acoustique Service Preparation pharmaceutique pour le traitement des acouphenes
WO2006055672A2 (en) * 2004-11-16 2006-05-26 Limerick Neurosciences, Inc. Methods and compositions for treating pain
US20070087977A1 (en) * 2004-11-16 2007-04-19 Wendye Robbins Methods and compositions for treating pain
ES2398579T3 (es) 2005-09-19 2013-03-20 Teva Pharmaceutical Industries Ltd Una síntesis asimétrica de ácido (S)-(+)-3-(aminometil)-5-metilhexanoico
MXPA05011735A (es) * 2005-11-01 2007-04-30 Leopoldo Espinosa Abdala Composiciones farmaceuticas que comprenden combinaciones de analgesicos y anticonvulsivantes para el tratamiento del dolor agudo y cronico.
US20090176882A1 (en) 2008-12-09 2009-07-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
EP2125021B8 (en) * 2006-12-22 2012-02-15 Recordati Ireland Limited Combination therapy of lower urinary tract disorders with alpha 2delta ligands and nsaids
MX2007006091A (es) * 2007-05-21 2009-02-25 World Trade Imp Export Wtie Ag Composicion farmaceutica que comprende la combinacion de un agente antiinflamatorio no esteroideo y un agente anticonvulsionante.
EP2184986A4 (en) * 2007-08-06 2010-12-15 Trinity Lab Inc PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CHRONIC PAIN AND PAIN RELATING TO NEUROPATHY
JP2010043063A (ja) 2008-05-09 2010-02-25 Agency For Science Technology & Research 川崎病の診断及び治療
WO2009158343A1 (en) * 2008-06-23 2009-12-30 Teva Pharmaceutical Industries, Ltd. Stereoselective enzymatic synthesis of (s) or (r)-iso-butyl-glutaric ester
FR2934267B1 (fr) * 2008-07-23 2010-08-13 Pharmaleads Derives aminophosphiniques utiles dans le traitement de la douleur
US20100190752A1 (en) 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
AU2009296457A1 (en) 2008-09-27 2010-04-01 Taraxos Inc. Topical formulations for treatment of neuropathy
CA2740087C (en) 2008-10-08 2019-07-23 Kyphia Pharmaceuticals, Inc. Gaba conjugates and methods of use thereof
WO2012015027A1 (ja) * 2010-07-30 2012-02-02 東レ株式会社 神経障害性疼痛の治療剤又は予防剤
WO2013076339A1 (es) * 2011-11-22 2013-05-30 Servicio Andaluz De Salud Composiciones y preparaciones combinadas para el tratamiento de la fibromialgia
US9545415B2 (en) * 2012-01-06 2017-01-17 Skyview Enterprise Ltd. Anti-inflammatory compounds in combination with hydrogen for the treatment of inflammation
FR2998892B1 (fr) 2012-12-04 2015-01-02 Pf Medicament Derives d'aminocyclobutane, leur procede de preparation et leur utilisation a titre de medicaments
MX378004B (es) 2015-12-02 2025-03-10 Jaime Samuel CHAIT AUERBACH Composición oral veterinaria con gabapentina.
KR102631399B1 (ko) * 2018-03-30 2024-02-01 씨지인바이츠 주식회사 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물
MX384760B (es) * 2018-07-04 2025-03-14 Federico Amezcua Amezcua Combinación farmacéutica sinérgica del enantiómero activo s-ketorolaco y gabapentina para el tratamiento del dolor neuropático.
MX388067B (es) * 2019-07-16 2025-03-19 Federico Amezcua Amezcua Combinacion sinergica de s-ketorolaco y pregabalina en una composicion farmaceutica para el tratamiento del dolor neuropatico
US11147780B2 (en) * 2020-02-24 2021-10-19 Algia Pharma, Llc Multidrug pain management package

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US6451857B1 (en) 1999-03-10 2002-09-17 Warner-Lambert Company Analgesic compositions comprising anti-epileptic compounds and methods of using same

Also Published As

Publication number Publication date
IS5362A (is) 2000-01-25
NZ502671A (en) 2003-01-31
CA2296336C (en) 2004-04-20
IL185345A0 (en) 2008-01-06
AU9198798A (en) 1999-03-29
NO20001175L (no) 2000-03-07
DK1011658T3 (da) 2006-04-03
HUP0003705A3 (en) 2002-01-28
PL339142A1 (en) 2000-12-04
KR20010023745A (ko) 2001-03-26
NO20001175D0 (no) 2000-03-07
US6942876B2 (en) 2005-09-13
DE69832712D1 (de) 2006-01-12
KR100537707B1 (ko) 2005-12-20
US20030176505A1 (en) 2003-09-18
ZA988159B (en) 1999-03-11
ATE311867T1 (de) 2005-12-15
AU750578B2 (en) 2002-07-25
JP2001515859A (ja) 2001-09-25
WO1999012537A1 (en) 1999-03-18
HU226165B1 (en) 2008-05-28
BR9812162A (pt) 2000-07-18
US20020115705A1 (en) 2002-08-22
NO324122B1 (no) 2007-08-27
ES2253825T3 (es) 2006-06-01
EP1011658A1 (en) 2000-06-28
IL134165A0 (en) 2001-04-30
HUP0003705A2 (hu) 2001-04-28
JP3782935B2 (ja) 2006-06-07
US6593368B2 (en) 2003-07-15
CA2296336A1 (en) 1999-03-18
EP1011658B1 (en) 2005-12-07
US20030065028A1 (en) 2003-04-03
CU23226B7 (es) 2007-09-26

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8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: DERZEIT KEIN VERTRETER BESTELLT

8339 Ceased/non-payment of the annual fee