BR9812162A - Composições analgésicas compreendendo compostos antiepiléticos e métodos para o uso das mesmas - Google Patents

Composições analgésicas compreendendo compostos antiepiléticos e métodos para o uso das mesmas

Info

Publication number
BR9812162A
BR9812162A BR9812162-6A BR9812162A BR9812162A BR 9812162 A BR9812162 A BR 9812162A BR 9812162 A BR9812162 A BR 9812162A BR 9812162 A BR9812162 A BR 9812162A
Authority
BR
Brazil
Prior art keywords
pain
compounds
methods
new combinations
antiepileptic
Prior art date
Application number
BR9812162-6A
Other languages
English (en)
Portuguese (pt)
Inventor
Leslie Magnus-Miller
Douglas A Saltel
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of BR9812162A publication Critical patent/BR9812162A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
BR9812162-6A 1997-09-08 1998-08-18 Composições analgésicas compreendendo compostos antiepiléticos e métodos para o uso das mesmas BR9812162A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5820797P 1997-09-08 1997-09-08
PCT/US1998/017083 WO1999012537A1 (en) 1997-09-08 1998-08-18 Analgesic compositions comprising anti-epileptic compounds and methods of using same

Publications (1)

Publication Number Publication Date
BR9812162A true BR9812162A (pt) 2000-07-18

Family

ID=22015361

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9812162-6A BR9812162A (pt) 1997-09-08 1998-08-18 Composições analgésicas compreendendo compostos antiepiléticos e métodos para o uso das mesmas

Country Status (20)

Country Link
US (3) US6593368B2 (enExample)
EP (1) EP1011658B1 (enExample)
JP (1) JP3782935B2 (enExample)
KR (1) KR100537707B1 (enExample)
AT (1) ATE311867T1 (enExample)
AU (1) AU750578B2 (enExample)
BR (1) BR9812162A (enExample)
CA (1) CA2296336C (enExample)
CU (1) CU23226B7 (enExample)
DE (1) DE69832712T2 (enExample)
DK (1) DK1011658T3 (enExample)
ES (1) ES2253825T3 (enExample)
HU (1) HU226165B1 (enExample)
IL (2) IL134165A0 (enExample)
IS (1) IS5362A (enExample)
NO (1) NO324122B1 (enExample)
NZ (1) NZ502671A (enExample)
PL (1) PL339142A1 (enExample)
WO (1) WO1999012537A1 (enExample)
ZA (1) ZA988159B (enExample)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU714980B2 (en) 1996-07-24 2000-01-13 Warner-Lambert Company Llc Isobutylgaba and its derivatives for the treatment of pain
HU226165B1 (en) 1997-09-08 2008-05-28 Warner Lambert Co Analgesic compositions comprising anti-epileptic compounds and non-steroid anti-inflammatory dr4gs
NZ508490A (en) 1998-07-09 2003-08-29 Warner Lambert Co Use of a combination of a GABA analog and caffeine as an analgesic
US6451857B1 (en) 1999-03-10 2002-09-17 Warner-Lambert Company Analgesic compositions comprising anti-epileptic compounds and methods of using same
CA2370030C (en) 1999-04-09 2007-08-14 Euro-Celtique S.A. Sodium channel blocker compositions and the use thereof
AU5824800A (en) * 1999-06-23 2001-01-31 Warner-Lambert Company Use of fosphenytoin for the treatment of acute neuropathic pain
EA006598B1 (ru) * 1999-08-20 2006-02-24 Орто-Макнейл Фармасьютикал, Инк. Композиция, содержащая трамадол и противосудорожное лекарственное средство
JP4350508B2 (ja) * 2001-09-03 2009-10-21 ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー ガバペンチンまたはその類似体とα−アミノアミドとを含む薬剤組成物およびその鎮痛用途
US7612112B2 (en) 2001-10-25 2009-11-03 Depomed, Inc. Methods of treatment using a gastric retained gabapentin dosage
US20070184104A1 (en) * 2001-10-25 2007-08-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
TWI312285B (en) * 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
US20060159743A1 (en) * 2001-10-25 2006-07-20 Depomed, Inc. Methods of treating non-nociceptive pain states with gastric retentive gabapentin
US6730667B2 (en) * 2001-11-26 2004-05-04 William R. Deagle Iontophoresis disc pain blocker
JP4428053B2 (ja) 2002-02-05 2010-03-10 味の素株式会社 ガバペンチン若しくはプレガバリンおよびｎ型カルシウムチャンネル拮抗剤を含有する医薬組成物
WO2003070237A1 (en) * 2002-02-22 2003-08-28 Warner-Lambert Company Llc Combinations of an alpha-2-delta ligand with a selective inhibitor of cyclooxygenase-2
DK1572173T3 (da) * 2002-12-13 2010-06-14 Warner Lambert Co Alpha-2-delta-ligand til behandling af symptomer i den nedre urinvej
FR2862875B1 (fr) * 2003-12-02 2006-04-07 Mathey Acoustique Service Preparation pharmaceutique pour le traitement des acouphenes
WO2006055672A2 (en) * 2004-11-16 2006-05-26 Limerick Neurosciences, Inc. Methods and compositions for treating pain
US20070087977A1 (en) * 2004-11-16 2007-04-19 Wendye Robbins Methods and compositions for treating pain
ES2398579T3 (es) 2005-09-19 2013-03-20 Teva Pharmaceutical Industries Ltd Una síntesis asimétrica de ácido (S)-(+)-3-(aminometil)-5-metilhexanoico
MXPA05011735A (es) * 2005-11-01 2007-04-30 Leopoldo Espinosa Abdala Composiciones farmaceuticas que comprenden combinaciones de analgesicos y anticonvulsivantes para el tratamiento del dolor agudo y cronico.
US20090176882A1 (en) 2008-12-09 2009-07-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
EP2125021B8 (en) * 2006-12-22 2012-02-15 Recordati Ireland Limited Combination therapy of lower urinary tract disorders with alpha 2delta ligands and nsaids
MX2007006091A (es) * 2007-05-21 2009-02-25 World Trade Imp Export Wtie Ag Composicion farmaceutica que comprende la combinacion de un agente antiinflamatorio no esteroideo y un agente anticonvulsionante.
EP2184986A4 (en) * 2007-08-06 2010-12-15 Trinity Lab Inc PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CHRONIC PAIN AND PAIN RELATING TO NEUROPATHY
JP2010043063A (ja) 2008-05-09 2010-02-25 Agency For Science Technology & Research 川崎病の診断及び治療
WO2009158343A1 (en) * 2008-06-23 2009-12-30 Teva Pharmaceutical Industries, Ltd. Stereoselective enzymatic synthesis of (s) or (r)-iso-butyl-glutaric ester
FR2934267B1 (fr) * 2008-07-23 2010-08-13 Pharmaleads Derives aminophosphiniques utiles dans le traitement de la douleur
US20100190752A1 (en) 2008-09-05 2010-07-29 Gruenenthal Gmbh Pharmaceutical Combination
AU2009296457A1 (en) 2008-09-27 2010-04-01 Taraxos Inc. Topical formulations for treatment of neuropathy
CA2740087C (en) 2008-10-08 2019-07-23 Kyphia Pharmaceuticals, Inc. Gaba conjugates and methods of use thereof
WO2012015027A1 (ja) * 2010-07-30 2012-02-02 東レ株式会社 神経障害性疼痛の治療剤又は予防剤
WO2013076339A1 (es) * 2011-11-22 2013-05-30 Servicio Andaluz De Salud Composiciones y preparaciones combinadas para el tratamiento de la fibromialgia
US9545415B2 (en) * 2012-01-06 2017-01-17 Skyview Enterprise Ltd. Anti-inflammatory compounds in combination with hydrogen for the treatment of inflammation
FR2998892B1 (fr) 2012-12-04 2015-01-02 Pf Medicament Derives d'aminocyclobutane, leur procede de preparation et leur utilisation a titre de medicaments
MX378004B (es) 2015-12-02 2025-03-10 Jaime Samuel CHAIT AUERBACH Composición oral veterinaria con gabapentina.
KR102631399B1 (ko) * 2018-03-30 2024-02-01 씨지인바이츠 주식회사 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물
MX384760B (es) * 2018-07-04 2025-03-14 Federico Amezcua Amezcua Combinación farmacéutica sinérgica del enantiómero activo s-ketorolaco y gabapentina para el tratamiento del dolor neuropático.
MX388067B (es) * 2019-07-16 2025-03-19 Federico Amezcua Amezcua Combinacion sinergica de s-ketorolaco y pregabalina en una composicion farmaceutica para el tratamiento del dolor neuropatico
US11147780B2 (en) * 2020-02-24 2021-10-19 Algia Pharma, Llc Multidrug pain management package

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE634102A (enExample)
DE1963925C3 (de) 1969-12-20 1975-07-10 Desitin-Werk, Carl Klinke Gmbh, 2000 Hamburg Verfahren zur Herstellung von N hoch 3-Carbalkoxyderivaten des 5,5-Diphenylhydantoins
DE2460891C2 (de) 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4087544A (en) 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
JPS54110334A (en) 1978-02-16 1979-08-29 Fuji Chem Ind Co Ltd Novel compounded anodyne and antiiinflammatory agent
JPS61221121A (ja) * 1985-03-27 1986-10-01 Nitto Electric Ind Co Ltd テ−プ製剤
US4694010A (en) 1985-08-16 1987-09-15 New York University Anticonvulsant compositions and method
JPH02502546A (ja) * 1987-12-22 1990-08-16 ファーカニー、ジョン　ダブリュ 抗ひきつけ剤組成物および方法のためのデキストロルファン相乗的協力剤
US6197819B1 (en) 1990-11-27 2001-03-06 Northwestern University Gamma amino butyric acid analogs and optical isomers
GB9108362D0 (en) * 1991-04-18 1991-06-05 Radoslavov Alexander A pharmaceutical composition suitable for alleviation of headaches,migraine and other painful conditions
ES2165857T3 (es) 1992-05-20 2002-04-01 Univ Northwestern Analogos de gaba y acido l-glutamico para el tratamiento de trastornos del sistema nervioso central.
US5234929A (en) * 1992-07-20 1993-08-10 William Chelen Method of treating motion sickness with anticonvulsants and antitussive agents
JPH06100468A (ja) 1992-09-25 1994-04-12 Kibun Food Chemifa Co Ltd 徐放性組成物
US5321012A (en) 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
JPH06227969A (ja) 1993-02-02 1994-08-16 Masayasu Sugihara 薬品の腸溶性改善方法およびそれにより得られた薬品組成物
US5420270A (en) 1993-10-07 1995-05-30 G. D. Searle & Co. Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US5466823A (en) * 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides
US5352638A (en) 1994-02-22 1994-10-04 Corning Incorporated Nickel aluminosilicate glass-ceramics
JPH10505087A (ja) 1994-09-02 1998-05-19 バージニア カマンウェルス ユニバーシティ 非麻薬性鎮痛剤および無痛エンハンサーを含有する疼痛緩和組成物
CN1046199C (zh) 1994-12-13 1999-11-10 凌吉安 复方消炎止痛霜剂
AU714980B2 (en) 1996-07-24 2000-01-13 Warner-Lambert Company Llc Isobutylgaba and its derivatives for the treatment of pain
WO1998007447A1 (en) * 1996-08-23 1998-02-26 Algos Pharmaceutical Corporation Anticonvulsant containing composition for treating neuropathic pain
US6057373A (en) 1997-05-22 2000-05-02 Synchroneuron, Llc Methods of treating tardive dyskinesia and other movement disorders using NMDA receptor antagonists
AU8668598A (en) 1997-08-20 1999-03-08 University Of Oklahoma, The Gaba analogs to prevent and treat gastrointestinal damage
US6127418A (en) 1997-08-20 2000-10-03 Warner-Lambert Company GABA analogs to prevent and treat gastrointestinal damage
HU226165B1 (en) 1997-09-08 2008-05-28 Warner Lambert Co Analgesic compositions comprising anti-epileptic compounds and non-steroid anti-inflammatory dr4gs
US6451857B1 (en) 1999-03-10 2002-09-17 Warner-Lambert Company Analgesic compositions comprising anti-epileptic compounds and methods of using same

Also Published As

Publication number Publication date
IS5362A (is) 2000-01-25
NZ502671A (en) 2003-01-31
CA2296336C (en) 2004-04-20
IL185345A0 (en) 2008-01-06
AU9198798A (en) 1999-03-29
NO20001175L (no) 2000-03-07
DK1011658T3 (da) 2006-04-03
DE69832712T2 (de) 2006-06-22
HUP0003705A3 (en) 2002-01-28
PL339142A1 (en) 2000-12-04
KR20010023745A (ko) 2001-03-26
NO20001175D0 (no) 2000-03-07
US6942876B2 (en) 2005-09-13
DE69832712D1 (de) 2006-01-12
KR100537707B1 (ko) 2005-12-20
US20030176505A1 (en) 2003-09-18
ZA988159B (en) 1999-03-11
ATE311867T1 (de) 2005-12-15
AU750578B2 (en) 2002-07-25
JP2001515859A (ja) 2001-09-25
WO1999012537A1 (en) 1999-03-18
HU226165B1 (en) 2008-05-28
US20020115705A1 (en) 2002-08-22
NO324122B1 (no) 2007-08-27
ES2253825T3 (es) 2006-06-01
EP1011658A1 (en) 2000-06-28
IL134165A0 (en) 2001-04-30
HUP0003705A2 (hu) 2001-04-28
JP3782935B2 (ja) 2006-06-07
US6593368B2 (en) 2003-07-15
CA2296336A1 (en) 1999-03-18
EP1011658B1 (en) 2005-12-07
US20030065028A1 (en) 2003-04-03
CU23226B7 (es) 2007-09-26

Similar Documents

Publication Publication Date Title
BR9812162A (pt) Composições analgésicas compreendendo compostos antiepiléticos e métodos para o uso das mesmas
BR0008847A (pt) Composições analgésicas que compreendemcompostos antiepilépticos, e métodos de uso dasmesmas
BR0111207A (pt) Combinações de um antagonista receptor de endotelina e um composto antiepiléptico tendo propriedades de alìvio da dor ou analgésicos
BR9908030A (pt) Composição farmacêutica compreendendo uma ou mais unidades de dose oralmente ministráveis, e, processos para prepará-la, para uso da mesma, e para tratar uma condição ou distúrbio médico em um indivìduo em que tratamento com um inibidor da ciclooxigenase-2 é indicado
BR0109150A (pt) Método para administração de um anestésico local a um indivìduo em necessidade de um efeito anestésico local, emplastro, composição, e, recipiente
BR9909903A (pt) Eficácia máxima de substâncias usadas para melhorar a saúde e bem-estar
BR0113447A (pt) Método de tratamento ou prevenção do câncer em um ser humano, e, composição farmacêutica
BR0012136A (pt) Inibidores de reabsorção de norepinefrina altamente seletivos e métodos de uso dos mesmos
Peppin et al. Skin matters: a review of topical treatments for chronic pain. Part two: treatments and applications
EP2335734A3 (en) Treatment of pain and other alpha 2 adrenergic-mediated conditions
AR040603A1 (es) El uso de un anticuerpo anti-tnfalfa neutralizador de alta afinidad en la fabricacion de un medicamento y conjunto de elementos
BR0016275A (pt) Combinações farmacêuticas e seu uso no tratamento de distúrbios gastrointestinais
BR9914901A (pt) Agonistas do receptor 5ht1 e metoclopramida para o tratamento de enxaqueca
Brown et al. Utilization and mechanism of action of tricyclic antidepressants in the treatment of chronic facial pain: a review of the literature
US20190374491A1 (en) Topical preparation for pain relief
JP7305654B2 (ja) ウォゴニンで疼痛を治療するための組成物および方法
BR0015407A (pt) Composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, métodos para estimular a liberação de hormÈnio do crescimento da glândula pituitária de um mamìfero e para aumentar a taxa e o grau de crescimento, a produção de leite e de lã ou para o tratamento de dores, e, uso de um composto ou um sal farmaceuticamente aceitável do mesmo
KR920703041A (ko) 통증을 수반하는 염증성 또는 알레르기성 질환치료에 사용되는 성분물과 그 방법
AR015744A1 (es) Uso de dexmedetomidina para sedacion en terapia intensiva
BR0201974A (pt) Composição farmacêutica para tratamento de alterações do sono
BR112023000598A2 (pt) Composições de dose oral unitária composta de ibuprofeno e famotidina para o tratamento da dor aguda e redução da gravidade e/ou risco de azia
US20050256187A1 (en) Method and composition for synergistic topical therapy for neuromuscular pains
Liu et al. Comparative study between three analgesic agents for the pain management during extracorporeal shock wave lithotripsy
Argoff A review of the use of topical analgesics for myofascial pain
KR890007728A (ko) 진통제 제조방법

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIMENTO DO PRESENTE PEDIDO COM BASE NO ARTIGOS 10 ( VIII ), 24 E 25 , 8O C/C 15, DA LPI 9.279, DE 14 DE MAIO DE 1996