JP3782935B2 - 抗癲癇化合物を含有する鎮痛剤組成物およびその使用方法 - Google Patents
抗癲癇化合物を含有する鎮痛剤組成物およびその使用方法 Download PDFInfo
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- JP3782935B2 JP3782935B2 JP2000510435A JP2000510435A JP3782935B2 JP 3782935 B2 JP3782935 B2 JP 3782935B2 JP 2000510435 A JP2000510435 A JP 2000510435A JP 2000510435 A JP2000510435 A JP 2000510435A JP 3782935 B2 JP3782935 B2 JP 3782935B2
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- pain
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- gabapentin
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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- Health & Medical Sciences (AREA)
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| PCT/US1998/017083 WO1999012537A1 (en) | 1997-09-08 | 1998-08-18 | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
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| AU714980B2 (en) | 1996-07-24 | 2000-01-13 | Warner-Lambert Company Llc | Isobutylgaba and its derivatives for the treatment of pain |
| HU226165B1 (en) | 1997-09-08 | 2008-05-28 | Warner Lambert Co | Analgesic compositions comprising anti-epileptic compounds and non-steroid anti-inflammatory dr4gs |
| NZ508490A (en) | 1998-07-09 | 2003-08-29 | Warner Lambert Co | Use of a combination of a GABA analog and caffeine as an analgesic |
| US6451857B1 (en) | 1999-03-10 | 2002-09-17 | Warner-Lambert Company | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
| CA2370030C (en) | 1999-04-09 | 2007-08-14 | Euro-Celtique S.A. | Sodium channel blocker compositions and the use thereof |
| AU5824800A (en) * | 1999-06-23 | 2001-01-31 | Warner-Lambert Company | Use of fosphenytoin for the treatment of acute neuropathic pain |
| EA006598B1 (ru) * | 1999-08-20 | 2006-02-24 | Орто-Макнейл Фармасьютикал, Инк. | Композиция, содержащая трамадол и противосудорожное лекарственное средство |
| JP4350508B2 (ja) * | 2001-09-03 | 2009-10-21 | ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー | ガバペンチンまたはその類似体とα−アミノアミドとを含む薬剤組成物およびその鎮痛用途 |
| US7612112B2 (en) | 2001-10-25 | 2009-11-03 | Depomed, Inc. | Methods of treatment using a gastric retained gabapentin dosage |
| US20070184104A1 (en) * | 2001-10-25 | 2007-08-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
| TWI312285B (en) * | 2001-10-25 | 2009-07-21 | Depomed Inc | Methods of treatment using a gastric retained gabapentin dosage |
| US20060159743A1 (en) * | 2001-10-25 | 2006-07-20 | Depomed, Inc. | Methods of treating non-nociceptive pain states with gastric retentive gabapentin |
| US6730667B2 (en) * | 2001-11-26 | 2004-05-04 | William R. Deagle | Iontophoresis disc pain blocker |
| JP4428053B2 (ja) | 2002-02-05 | 2010-03-10 | 味の素株式会社 | ガバペンチン若しくはプレガバリンおよびｎ型カルシウムチャンネル拮抗剤を含有する医薬組成物 |
| WO2003070237A1 (en) * | 2002-02-22 | 2003-08-28 | Warner-Lambert Company Llc | Combinations of an alpha-2-delta ligand with a selective inhibitor of cyclooxygenase-2 |
| DK1572173T3 (da) * | 2002-12-13 | 2010-06-14 | Warner Lambert Co | Alpha-2-delta-ligand til behandling af symptomer i den nedre urinvej |
| FR2862875B1 (fr) * | 2003-12-02 | 2006-04-07 | Mathey Acoustique Service | Preparation pharmaceutique pour le traitement des acouphenes |
| WO2006055672A2 (en) * | 2004-11-16 | 2006-05-26 | Limerick Neurosciences, Inc. | Methods and compositions for treating pain |
| US20070087977A1 (en) * | 2004-11-16 | 2007-04-19 | Wendye Robbins | Methods and compositions for treating pain |
| ES2398579T3 (es) | 2005-09-19 | 2013-03-20 | Teva Pharmaceutical Industries Ltd | Una síntesis asimétrica de ácido (S)-(+)-3-(aminometil)-5-metilhexanoico |
| MXPA05011735A (es) * | 2005-11-01 | 2007-04-30 | Leopoldo Espinosa Abdala | Composiciones farmaceuticas que comprenden combinaciones de analgesicos y anticonvulsivantes para el tratamiento del dolor agudo y cronico. |
| US20090176882A1 (en) | 2008-12-09 | 2009-07-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
| EP2125021B8 (en) * | 2006-12-22 | 2012-02-15 | Recordati Ireland Limited | Combination therapy of lower urinary tract disorders with alpha 2delta ligands and nsaids |
| MX2007006091A (es) * | 2007-05-21 | 2009-02-25 | World Trade Imp Export Wtie Ag | Composicion farmaceutica que comprende la combinacion de un agente antiinflamatorio no esteroideo y un agente anticonvulsionante. |
| EP2184986A4 (en) * | 2007-08-06 | 2010-12-15 | Trinity Lab Inc | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CHRONIC PAIN AND PAIN RELATING TO NEUROPATHY |
| JP2010043063A (ja) | 2008-05-09 | 2010-02-25 | Agency For Science Technology & Research | 川崎病の診断及び治療 |
| WO2009158343A1 (en) * | 2008-06-23 | 2009-12-30 | Teva Pharmaceutical Industries, Ltd. | Stereoselective enzymatic synthesis of (s) or (r)-iso-butyl-glutaric ester |
| FR2934267B1 (fr) * | 2008-07-23 | 2010-08-13 | Pharmaleads | Derives aminophosphiniques utiles dans le traitement de la douleur |
| US20100190752A1 (en) | 2008-09-05 | 2010-07-29 | Gruenenthal Gmbh | Pharmaceutical Combination |
| AU2009296457A1 (en) | 2008-09-27 | 2010-04-01 | Taraxos Inc. | Topical formulations for treatment of neuropathy |
| CA2740087C (en) | 2008-10-08 | 2019-07-23 | Kyphia Pharmaceuticals, Inc. | Gaba conjugates and methods of use thereof |
| WO2012015027A1 (ja) * | 2010-07-30 | 2012-02-02 | 東レ株式会社 | 神経障害性疼痛の治療剤又は予防剤 |
| WO2013076339A1 (es) * | 2011-11-22 | 2013-05-30 | Servicio Andaluz De Salud | Composiciones y preparaciones combinadas para el tratamiento de la fibromialgia |
| US9545415B2 (en) * | 2012-01-06 | 2017-01-17 | Skyview Enterprise Ltd. | Anti-inflammatory compounds in combination with hydrogen for the treatment of inflammation |
| FR2998892B1 (fr) | 2012-12-04 | 2015-01-02 | Pf Medicament | Derives d'aminocyclobutane, leur procede de preparation et leur utilisation a titre de medicaments |
| MX378004B (es) | 2015-12-02 | 2025-03-10 | Jaime Samuel CHAIT AUERBACH | Composición oral veterinaria con gabapentina. |
| KR102631399B1 (ko) * | 2018-03-30 | 2024-02-01 | 씨지인바이츠 주식회사 | 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물 |
| MX384760B (es) * | 2018-07-04 | 2025-03-14 | Federico Amezcua Amezcua | Combinación farmacéutica sinérgica del enantiómero activo s-ketorolaco y gabapentina para el tratamiento del dolor neuropático. |
| MX388067B (es) * | 2019-07-16 | 2025-03-19 | Federico Amezcua Amezcua | Combinacion sinergica de s-ketorolaco y pregabalina en una composicion farmaceutica para el tratamiento del dolor neuropatico |
| US11147780B2 (en) * | 2020-02-24 | 2021-10-19 | Algia Pharma, Llc | Multidrug pain management package |
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| DE2460891C2 (de) | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
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1998
- 1998-08-18 HU HU0003705A patent/HU226165B1/hu not_active IP Right Cessation
- 1998-08-18 BR BR9812162-6A patent/BR9812162A/pt not_active Application Discontinuation
- 1998-08-18 NZ NZ502671A patent/NZ502671A/xx unknown
- 1998-08-18 CA CA002296336A patent/CA2296336C/en not_active Expired - Fee Related
- 1998-08-18 WO PCT/US1998/017083 patent/WO1999012537A1/en not_active Ceased
- 1998-08-18 KR KR10-2000-7002400A patent/KR100537707B1/ko not_active Expired - Fee Related
- 1998-08-18 AU AU91987/98A patent/AU750578B2/en not_active Ceased
- 1998-08-18 IL IL13416598A patent/IL134165A0/xx unknown
- 1998-08-18 JP JP2000510435A patent/JP3782935B2/ja not_active Expired - Fee Related
- 1998-08-18 DK DK98944449T patent/DK1011658T3/da active
- 1998-08-18 EP EP98944449A patent/EP1011658B1/en not_active Expired - Lifetime
- 1998-08-18 US US09/463,116 patent/US6593368B2/en not_active Expired - Fee Related
- 1998-08-18 ES ES98944449T patent/ES2253825T3/es not_active Expired - Lifetime
- 1998-08-18 AT AT98944449T patent/ATE311867T1/de not_active IP Right Cessation
- 1998-08-18 PL PL98339142A patent/PL339142A1/xx not_active Application Discontinuation
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- 1998-09-07 ZA ZA988159A patent/ZA988159B/xx unknown
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2000
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- 2000-03-07 NO NO20001175A patent/NO324122B1/no not_active IP Right Cessation
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2002
- 2002-02-13 US US10/075,929 patent/US6942876B2/en not_active Expired - Fee Related
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2003
- 2003-04-04 US US10/407,888 patent/US20030176505A1/en not_active Abandoned
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| IS5362A (is) | 2000-01-25 |
| NZ502671A (en) | 2003-01-31 |
| CA2296336C (en) | 2004-04-20 |
| IL185345A0 (en) | 2008-01-06 |
| AU9198798A (en) | 1999-03-29 |
| NO20001175L (no) | 2000-03-07 |
| DK1011658T3 (da) | 2006-04-03 |
| DE69832712T2 (de) | 2006-06-22 |
| HUP0003705A3 (en) | 2002-01-28 |
| PL339142A1 (en) | 2000-12-04 |
| KR20010023745A (ko) | 2001-03-26 |
| NO20001175D0 (no) | 2000-03-07 |
| US6942876B2 (en) | 2005-09-13 |
| DE69832712D1 (de) | 2006-01-12 |
| KR100537707B1 (ko) | 2005-12-20 |
| US20030176505A1 (en) | 2003-09-18 |
| ZA988159B (en) | 1999-03-11 |
| ATE311867T1 (de) | 2005-12-15 |
| AU750578B2 (en) | 2002-07-25 |
| JP2001515859A (ja) | 2001-09-25 |
| WO1999012537A1 (en) | 1999-03-18 |
| HU226165B1 (en) | 2008-05-28 |
| BR9812162A (pt) | 2000-07-18 |
| US20020115705A1 (en) | 2002-08-22 |
| NO324122B1 (no) | 2007-08-27 |
| ES2253825T3 (es) | 2006-06-01 |
| EP1011658A1 (en) | 2000-06-28 |
| IL134165A0 (en) | 2001-04-30 |
| HUP0003705A2 (hu) | 2001-04-28 |
| US6593368B2 (en) | 2003-07-15 |
| CA2296336A1 (en) | 1999-03-18 |
| EP1011658B1 (en) | 2005-12-07 |
| US20030065028A1 (en) | 2003-04-03 |
| CU23226B7 (es) | 2007-09-26 |
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