DK1011658T3 - Analgesiske præparater, der omfatter antiepileptiske forbindelser, og fremgangsmåder til anvendelse af samme - Google Patents
Analgesiske præparater, der omfatter antiepileptiske forbindelser, og fremgangsmåder til anvendelse af sammeInfo
- Publication number
- DK1011658T3 DK1011658T3 DK98944449T DK98944449T DK1011658T3 DK 1011658 T3 DK1011658 T3 DK 1011658T3 DK 98944449 T DK98944449 T DK 98944449T DK 98944449 T DK98944449 T DK 98944449T DK 1011658 T3 DK1011658 T3 DK 1011658T3
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- pain
- same
- compounds
- novel combinations
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 230000003556 anti-epileptic effect Effects 0.000 title abstract 3
- 239000001961 anticonvulsive agent Substances 0.000 title abstract 3
- 230000000202 analgesic effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 229940127523 NMDA Receptor Antagonists Drugs 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 abstract 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5820797P | 1997-09-08 | 1997-09-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1011658T3 true DK1011658T3 (da) | 2006-04-03 |
Family
ID=22015361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98944449T DK1011658T3 (da) | 1997-09-08 | 1998-08-18 | Analgesiske præparater, der omfatter antiepileptiske forbindelser, og fremgangsmåder til anvendelse af samme |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US6593368B2 (enExample) |
| EP (1) | EP1011658B1 (enExample) |
| JP (1) | JP3782935B2 (enExample) |
| KR (1) | KR100537707B1 (enExample) |
| AT (1) | ATE311867T1 (enExample) |
| AU (1) | AU750578B2 (enExample) |
| BR (1) | BR9812162A (enExample) |
| CA (1) | CA2296336C (enExample) |
| CU (1) | CU23226B7 (enExample) |
| DE (1) | DE69832712T2 (enExample) |
| DK (1) | DK1011658T3 (enExample) |
| ES (1) | ES2253825T3 (enExample) |
| HU (1) | HU226165B1 (enExample) |
| IL (2) | IL134165A0 (enExample) |
| IS (1) | IS5362A (enExample) |
| NO (1) | NO324122B1 (enExample) |
| NZ (1) | NZ502671A (enExample) |
| PL (1) | PL339142A1 (enExample) |
| WO (1) | WO1999012537A1 (enExample) |
| ZA (1) | ZA988159B (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU714980B2 (en) | 1996-07-24 | 2000-01-13 | Warner-Lambert Company Llc | Isobutylgaba and its derivatives for the treatment of pain |
| HU226165B1 (en) | 1997-09-08 | 2008-05-28 | Warner Lambert Co | Analgesic compositions comprising anti-epileptic compounds and non-steroid anti-inflammatory dr4gs |
| NZ508490A (en) | 1998-07-09 | 2003-08-29 | Warner Lambert Co | Use of a combination of a GABA analog and caffeine as an analgesic |
| US6451857B1 (en) | 1999-03-10 | 2002-09-17 | Warner-Lambert Company | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
| CA2370030C (en) | 1999-04-09 | 2007-08-14 | Euro-Celtique S.A. | Sodium channel blocker compositions and the use thereof |
| AU5824800A (en) * | 1999-06-23 | 2001-01-31 | Warner-Lambert Company | Use of fosphenytoin for the treatment of acute neuropathic pain |
| EA006598B1 (ru) * | 1999-08-20 | 2006-02-24 | Орто-Макнейл Фармасьютикал, Инк. | Композиция, содержащая трамадол и противосудорожное лекарственное средство |
| JP4350508B2 (ja) * | 2001-09-03 | 2009-10-21 | ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー | ガバペンチンまたはその類似体とα−アミノアミドとを含む薬剤組成物およびその鎮痛用途 |
| US7612112B2 (en) | 2001-10-25 | 2009-11-03 | Depomed, Inc. | Methods of treatment using a gastric retained gabapentin dosage |
| US20070184104A1 (en) * | 2001-10-25 | 2007-08-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
| TWI312285B (en) * | 2001-10-25 | 2009-07-21 | Depomed Inc | Methods of treatment using a gastric retained gabapentin dosage |
| US20060159743A1 (en) * | 2001-10-25 | 2006-07-20 | Depomed, Inc. | Methods of treating non-nociceptive pain states with gastric retentive gabapentin |
| US6730667B2 (en) * | 2001-11-26 | 2004-05-04 | William R. Deagle | Iontophoresis disc pain blocker |
| JP4428053B2 (ja) | 2002-02-05 | 2010-03-10 | 味の素株式会社 | ガバペンチン若しくはプレガバリンおよびn型カルシウムチャンネル拮抗剤を含有する医薬組成物 |
| WO2003070237A1 (en) * | 2002-02-22 | 2003-08-28 | Warner-Lambert Company Llc | Combinations of an alpha-2-delta ligand with a selective inhibitor of cyclooxygenase-2 |
| DK1572173T3 (da) * | 2002-12-13 | 2010-06-14 | Warner Lambert Co | Alpha-2-delta-ligand til behandling af symptomer i den nedre urinvej |
| FR2862875B1 (fr) * | 2003-12-02 | 2006-04-07 | Mathey Acoustique Service | Preparation pharmaceutique pour le traitement des acouphenes |
| WO2006055672A2 (en) * | 2004-11-16 | 2006-05-26 | Limerick Neurosciences, Inc. | Methods and compositions for treating pain |
| US20070087977A1 (en) * | 2004-11-16 | 2007-04-19 | Wendye Robbins | Methods and compositions for treating pain |
| ES2398579T3 (es) | 2005-09-19 | 2013-03-20 | Teva Pharmaceutical Industries Ltd | Una síntesis asimétrica de ácido (S)-(+)-3-(aminometil)-5-metilhexanoico |
| MXPA05011735A (es) * | 2005-11-01 | 2007-04-30 | Leopoldo Espinosa Abdala | Composiciones farmaceuticas que comprenden combinaciones de analgesicos y anticonvulsivantes para el tratamiento del dolor agudo y cronico. |
| US20090176882A1 (en) | 2008-12-09 | 2009-07-09 | Depomed, Inc. | Gastric retentive gabapentin dosage forms and methods for using same |
| EP2125021B8 (en) * | 2006-12-22 | 2012-02-15 | Recordati Ireland Limited | Combination therapy of lower urinary tract disorders with alpha 2delta ligands and nsaids |
| MX2007006091A (es) * | 2007-05-21 | 2009-02-25 | World Trade Imp Export Wtie Ag | Composicion farmaceutica que comprende la combinacion de un agente antiinflamatorio no esteroideo y un agente anticonvulsionante. |
| EP2184986A4 (en) * | 2007-08-06 | 2010-12-15 | Trinity Lab Inc | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CHRONIC PAIN AND PAIN RELATING TO NEUROPATHY |
| JP2010043063A (ja) | 2008-05-09 | 2010-02-25 | Agency For Science Technology & Research | 川崎病の診断及び治療 |
| WO2009158343A1 (en) * | 2008-06-23 | 2009-12-30 | Teva Pharmaceutical Industries, Ltd. | Stereoselective enzymatic synthesis of (s) or (r)-iso-butyl-glutaric ester |
| FR2934267B1 (fr) * | 2008-07-23 | 2010-08-13 | Pharmaleads | Derives aminophosphiniques utiles dans le traitement de la douleur |
| US20100190752A1 (en) | 2008-09-05 | 2010-07-29 | Gruenenthal Gmbh | Pharmaceutical Combination |
| AU2009296457A1 (en) | 2008-09-27 | 2010-04-01 | Taraxos Inc. | Topical formulations for treatment of neuropathy |
| CA2740087C (en) | 2008-10-08 | 2019-07-23 | Kyphia Pharmaceuticals, Inc. | Gaba conjugates and methods of use thereof |
| WO2012015027A1 (ja) * | 2010-07-30 | 2012-02-02 | 東レ株式会社 | 神経障害性疼痛の治療剤又は予防剤 |
| WO2013076339A1 (es) * | 2011-11-22 | 2013-05-30 | Servicio Andaluz De Salud | Composiciones y preparaciones combinadas para el tratamiento de la fibromialgia |
| US9545415B2 (en) * | 2012-01-06 | 2017-01-17 | Skyview Enterprise Ltd. | Anti-inflammatory compounds in combination with hydrogen for the treatment of inflammation |
| FR2998892B1 (fr) | 2012-12-04 | 2015-01-02 | Pf Medicament | Derives d'aminocyclobutane, leur procede de preparation et leur utilisation a titre de medicaments |
| MX378004B (es) | 2015-12-02 | 2025-03-10 | Jaime Samuel CHAIT AUERBACH | Composición oral veterinaria con gabapentina. |
| KR102631399B1 (ko) * | 2018-03-30 | 2024-02-01 | 씨지인바이츠 주식회사 | 폴마콕시브 및 프레가발린을 포함하는 통증 치료용 약제학적 조성물 |
| MX384760B (es) * | 2018-07-04 | 2025-03-14 | Federico Amezcua Amezcua | Combinación farmacéutica sinérgica del enantiómero activo s-ketorolaco y gabapentina para el tratamiento del dolor neuropático. |
| MX388067B (es) * | 2019-07-16 | 2025-03-19 | Federico Amezcua Amezcua | Combinacion sinergica de s-ketorolaco y pregabalina en una composicion farmaceutica para el tratamiento del dolor neuropatico |
| US11147780B2 (en) * | 2020-02-24 | 2021-10-19 | Algia Pharma, Llc | Multidrug pain management package |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE634102A (enExample) | ||||
| DE1963925C3 (de) | 1969-12-20 | 1975-07-10 | Desitin-Werk, Carl Klinke Gmbh, 2000 Hamburg | Verfahren zur Herstellung von N hoch 3-Carbalkoxyderivaten des 5,5-Diphenylhydantoins |
| DE2460891C2 (de) | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US4087544A (en) | 1974-12-21 | 1978-05-02 | Warner-Lambert Company | Treatment of cranial dysfunctions using novel cyclic amino acids |
| JPS54110334A (en) | 1978-02-16 | 1979-08-29 | Fuji Chem Ind Co Ltd | Novel compounded anodyne and antiiinflammatory agent |
| JPS61221121A (ja) * | 1985-03-27 | 1986-10-01 | Nitto Electric Ind Co Ltd | テ−プ製剤 |
| US4694010A (en) | 1985-08-16 | 1987-09-15 | New York University | Anticonvulsant compositions and method |
| JPH02502546A (ja) * | 1987-12-22 | 1990-08-16 | ファーカニー、ジョン ダブリュ | 抗ひきつけ剤組成物および方法のためのデキストロルファン相乗的協力剤 |
| US6197819B1 (en) | 1990-11-27 | 2001-03-06 | Northwestern University | Gamma amino butyric acid analogs and optical isomers |
| GB9108362D0 (en) * | 1991-04-18 | 1991-06-05 | Radoslavov Alexander | A pharmaceutical composition suitable for alleviation of headaches,migraine and other painful conditions |
| ES2165857T3 (es) | 1992-05-20 | 2002-04-01 | Univ Northwestern | Analogos de gaba y acido l-glutamico para el tratamiento de trastornos del sistema nervioso central. |
| US5234929A (en) * | 1992-07-20 | 1993-08-10 | William Chelen | Method of treating motion sickness with anticonvulsants and antitussive agents |
| JPH06100468A (ja) | 1992-09-25 | 1994-04-12 | Kibun Food Chemifa Co Ltd | 徐放性組成物 |
| US5321012A (en) | 1993-01-28 | 1994-06-14 | Virginia Commonwealth University Medical College | Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance |
| JPH06227969A (ja) | 1993-02-02 | 1994-08-16 | Masayasu Sugihara | 薬品の腸溶性改善方法およびそれにより得られた薬品組成物 |
| US5420270A (en) | 1993-10-07 | 1995-05-30 | G. D. Searle & Co. | Aryl substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use |
| US5466823A (en) * | 1993-11-30 | 1995-11-14 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides |
| US5352638A (en) | 1994-02-22 | 1994-10-04 | Corning Incorporated | Nickel aluminosilicate glass-ceramics |
| JPH10505087A (ja) | 1994-09-02 | 1998-05-19 | バージニア カマンウェルス ユニバーシティ | 非麻薬性鎮痛剤および無痛エンハンサーを含有する疼痛緩和組成物 |
| CN1046199C (zh) | 1994-12-13 | 1999-11-10 | 凌吉安 | 复方消炎止痛霜剂 |
| AU714980B2 (en) | 1996-07-24 | 2000-01-13 | Warner-Lambert Company Llc | Isobutylgaba and its derivatives for the treatment of pain |
| WO1998007447A1 (en) * | 1996-08-23 | 1998-02-26 | Algos Pharmaceutical Corporation | Anticonvulsant containing composition for treating neuropathic pain |
| US6057373A (en) | 1997-05-22 | 2000-05-02 | Synchroneuron, Llc | Methods of treating tardive dyskinesia and other movement disorders using NMDA receptor antagonists |
| AU8668598A (en) | 1997-08-20 | 1999-03-08 | University Of Oklahoma, The | Gaba analogs to prevent and treat gastrointestinal damage |
| US6127418A (en) | 1997-08-20 | 2000-10-03 | Warner-Lambert Company | GABA analogs to prevent and treat gastrointestinal damage |
| HU226165B1 (en) | 1997-09-08 | 2008-05-28 | Warner Lambert Co | Analgesic compositions comprising anti-epileptic compounds and non-steroid anti-inflammatory dr4gs |
| US6451857B1 (en) | 1999-03-10 | 2002-09-17 | Warner-Lambert Company | Analgesic compositions comprising anti-epileptic compounds and methods of using same |
-
1998
- 1998-08-18 HU HU0003705A patent/HU226165B1/hu not_active IP Right Cessation
- 1998-08-18 BR BR9812162-6A patent/BR9812162A/pt not_active Application Discontinuation
- 1998-08-18 NZ NZ502671A patent/NZ502671A/xx unknown
- 1998-08-18 CA CA002296336A patent/CA2296336C/en not_active Expired - Fee Related
- 1998-08-18 WO PCT/US1998/017083 patent/WO1999012537A1/en not_active Ceased
- 1998-08-18 KR KR10-2000-7002400A patent/KR100537707B1/ko not_active Expired - Fee Related
- 1998-08-18 AU AU91987/98A patent/AU750578B2/en not_active Ceased
- 1998-08-18 IL IL13416598A patent/IL134165A0/xx unknown
- 1998-08-18 JP JP2000510435A patent/JP3782935B2/ja not_active Expired - Fee Related
- 1998-08-18 DK DK98944449T patent/DK1011658T3/da active
- 1998-08-18 EP EP98944449A patent/EP1011658B1/en not_active Expired - Lifetime
- 1998-08-18 US US09/463,116 patent/US6593368B2/en not_active Expired - Fee Related
- 1998-08-18 ES ES98944449T patent/ES2253825T3/es not_active Expired - Lifetime
- 1998-08-18 AT AT98944449T patent/ATE311867T1/de not_active IP Right Cessation
- 1998-08-18 PL PL98339142A patent/PL339142A1/xx not_active Application Discontinuation
- 1998-08-18 DE DE69832712T patent/DE69832712T2/de not_active Expired - Fee Related
- 1998-09-07 ZA ZA988159A patent/ZA988159B/xx unknown
-
2000
- 2000-01-25 IS IS5362A patent/IS5362A/is unknown
- 2000-03-03 CU CU20000051A patent/CU23226B7/es not_active IP Right Cessation
- 2000-03-07 NO NO20001175A patent/NO324122B1/no not_active IP Right Cessation
-
2002
- 2002-02-13 US US10/075,929 patent/US6942876B2/en not_active Expired - Fee Related
-
2003
- 2003-04-04 US US10/407,888 patent/US20030176505A1/en not_active Abandoned
-
2007
- 2007-08-16 IL IL185345A patent/IL185345A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IS5362A (is) | 2000-01-25 |
| NZ502671A (en) | 2003-01-31 |
| CA2296336C (en) | 2004-04-20 |
| IL185345A0 (en) | 2008-01-06 |
| AU9198798A (en) | 1999-03-29 |
| NO20001175L (no) | 2000-03-07 |
| DE69832712T2 (de) | 2006-06-22 |
| HUP0003705A3 (en) | 2002-01-28 |
| PL339142A1 (en) | 2000-12-04 |
| KR20010023745A (ko) | 2001-03-26 |
| NO20001175D0 (no) | 2000-03-07 |
| US6942876B2 (en) | 2005-09-13 |
| DE69832712D1 (de) | 2006-01-12 |
| KR100537707B1 (ko) | 2005-12-20 |
| US20030176505A1 (en) | 2003-09-18 |
| ZA988159B (en) | 1999-03-11 |
| ATE311867T1 (de) | 2005-12-15 |
| AU750578B2 (en) | 2002-07-25 |
| JP2001515859A (ja) | 2001-09-25 |
| WO1999012537A1 (en) | 1999-03-18 |
| HU226165B1 (en) | 2008-05-28 |
| BR9812162A (pt) | 2000-07-18 |
| US20020115705A1 (en) | 2002-08-22 |
| NO324122B1 (no) | 2007-08-27 |
| ES2253825T3 (es) | 2006-06-01 |
| EP1011658A1 (en) | 2000-06-28 |
| IL134165A0 (en) | 2001-04-30 |
| HUP0003705A2 (hu) | 2001-04-28 |
| JP3782935B2 (ja) | 2006-06-07 |
| US6593368B2 (en) | 2003-07-15 |
| CA2296336A1 (en) | 1999-03-18 |
| EP1011658B1 (en) | 2005-12-07 |
| US20030065028A1 (en) | 2003-04-03 |
| CU23226B7 (es) | 2007-09-26 |
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