RU94045866A - Применение бисфенилалкилпиперазинов для лечения расстройств, вызванных злоупотреблением веществами, способ лечения - Google Patents

Применение бисфенилалкилпиперазинов для лечения расстройств, вызванных злоупотреблением веществами, способ лечения

Info

Publication number
RU94045866A
RU94045866A RU94045866/14A RU94045866A RU94045866A RU 94045866 A RU94045866 A RU 94045866A RU 94045866/14 A RU94045866/14 A RU 94045866/14A RU 94045866 A RU94045866 A RU 94045866A RU 94045866 A RU94045866 A RU 94045866A
Authority
RU
Russia
Prior art keywords
treatment
phenylalkylpiperazines
bis
substance abuse
substance
Prior art date
Application number
RU94045866/14A
Other languages
English (en)
Other versions
RU2126254C1 (ru
Inventor
Бьерк Андрес
Se]
Андерссон Гуннар
Original Assignee
Фармациа Актиеболаг (SE)
Фармациа Актиеболаг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фармациа Актиеболаг (SE), Фармациа Актиеболаг filed Critical Фармациа Актиеболаг (SE)
Publication of RU94045866A publication Critical patent/RU94045866A/ru
Application granted granted Critical
Publication of RU2126254C1 publication Critical patent/RU2126254C1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Способ для ослабления или профилактики абстинентного синдрома, являющегося результатом чрезмерного употребления лекарственного средства или вещества злоупотребления и/или для подавления зависимости от лекарств или веществ зависимости, который включает применение эффективного количества бисфенилалкилпиперазинов и их фармацевтически приемлемых солей, полученных в результате присоединения кислоты.

Claims (1)

  1. Способ для ослабления или профилактики абстинентного синдрома, являющегося результатом чрезмерного употребления лекарственного средства или вещества злоупотребления и/или для подавления зависимости от лекарств или веществ зависимости, который включает применение эффективного количества бисфенилалкилпиперазинов и их фармацевтически приемлемых солей, полученных в результате присоединения кислоты.
RU94045866A 1992-04-21 1993-04-19 Применение бисфенилалкилпиперазинов для лечения расстройств, вызванных злоупотреблением веществами, и способ лечения RU2126254C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9201239-2 1992-04-21
SE9201239A SE9201239D0 (sv) 1992-04-21 1992-04-21 Agents for treating substance abuse disorders
PCT/SE1993/000339 WO1993020821A1 (en) 1992-04-21 1993-04-19 Agents for treating substance abuse disorders

Publications (2)

Publication Number Publication Date
RU94045866A true RU94045866A (ru) 1996-10-20
RU2126254C1 RU2126254C1 (ru) 1999-02-20

Family

ID=20386004

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94045866A RU2126254C1 (ru) 1992-04-21 1993-04-19 Применение бисфенилалкилпиперазинов для лечения расстройств, вызванных злоупотреблением веществами, и способ лечения

Country Status (26)

Country Link
US (1) US5565455A (ru)
EP (1) EP0637242B1 (ru)
JP (1) JP3245642B2 (ru)
KR (1) KR100321319B1 (ru)
AT (1) ATE184484T1 (ru)
AU (1) AU659941B2 (ru)
BG (1) BG62154B1 (ru)
BR (1) BR9306361A (ru)
CA (1) CA2118512C (ru)
CZ (1) CZ281296B6 (ru)
DE (1) DE69326459T2 (ru)
DK (1) DK0637242T3 (ru)
EE (1) EE02974B1 (ru)
ES (1) ES2139007T3 (ru)
GR (1) GR3032030T3 (ru)
HU (1) HU223463B1 (ru)
IL (1) IL105449A (ru)
NO (2) NO308827B1 (ru)
PH (1) PH31051A (ru)
RO (1) RO117150B1 (ru)
RU (1) RU2126254C1 (ru)
SE (1) SE9201239D0 (ru)
SK (1) SK279940B6 (ru)
UA (1) UA27884C2 (ru)
WO (1) WO1993020821A1 (ru)
ZA (1) ZA932757B (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5316759A (en) * 1986-03-17 1994-05-31 Robert J. Schaap Agonist-antagonist combination to reduce the use of nicotine and other drugs
SE9201956D0 (sv) * 1992-06-25 1992-06-25 Kabi Pharmacia Ab Novel nicotinicacid esters
SE9601708D0 (sv) * 1996-05-06 1996-05-06 Pharmacia Ab Pyridyl- and pyrimidyl-piperazines in the treatment of substance abuse disorders
RU2205179C2 (ru) 1997-10-27 2003-05-27 НьюроСёрч А/С Производное гомопиперазина и фармацевтическая композиция
US6632823B1 (en) * 1997-12-22 2003-10-14 Merck & Co., Inc. Substituted pyridine compounds useful as modulators of acetylcholine receptors
US6358060B2 (en) 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
US6344222B1 (en) 1998-09-03 2002-02-05 Jsr Llc Medicated chewing gum delivery system for nicotine
US6090780A (en) * 1999-04-07 2000-07-18 Chandon Prasad Histidyl-proline diketopiperazine and method of use
DK1551372T3 (en) 2002-09-20 2018-07-23 Alpharma Pharmaceuticals Llc SEQUERATION SUBSTANCES AND RELATED COMPOSITIONS AND PROCEDURES
CN101677963B (zh) 2006-06-19 2012-05-30 奥尔制药公司 药物组合物
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2958694A (en) * 1959-06-22 1960-11-01 Janssen Paul Adriaan Jan 1-(aroylalkyl)-4-(2'-pyridyl) piperazines
US2985657A (en) * 1959-10-12 1961-05-23 Paul A J Janssen 1-(aroylalkyl)-4-heterocyclylpiperazines
US2979508A (en) * 1959-10-12 1961-04-11 Paul A J Janssen Heterocyclic derivatives of 1-phenyl-omega-(piperazine) alkanols
NO154582C (no) * 1978-10-20 1986-11-05 Ferrosan Ab Analogifremgangsmaate for fremstilling av terapeutisk aktive difenyl-dibutylpiperazinkarboksamider.
US4605655A (en) * 1984-03-06 1986-08-12 Bristol-Myers Company Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
US4766215A (en) * 1987-02-27 1988-08-23 American Home Products Corporation Histamine H1 -receptor antagonists
SE8701375D0 (sv) * 1987-04-02 1987-04-02 Leo Ab Novel pyridyl- and pyrimidyl derivatives
US5217987A (en) * 1989-10-30 1993-06-08 Berger Stephen P Dopamine uptake inhibitors in reducing substance abuse and/or craving
SE9100860D0 (sv) * 1991-03-22 1991-03-22 Kabi Pharmacia Ab New use

Also Published As

Publication number Publication date
NO308827B1 (no) 2000-11-06
RU2126254C1 (ru) 1999-02-20
ATE184484T1 (de) 1999-10-15
KR100321319B1 (ko) 2002-07-27
NO318461B1 (no) 2005-03-21
CA2118512A1 (en) 1993-10-28
NO943977D0 (no) 1994-10-20
IL105449A (en) 1998-02-22
BG99129A (bg) 1995-08-28
BR9306361A (pt) 1998-06-30
SK279940B6 (sk) 1999-06-11
EP0637242A1 (en) 1995-02-08
HU9403020D0 (en) 1994-12-28
JPH08503449A (ja) 1996-04-16
NO20004169L (no) 1994-10-20
SK126994A3 (en) 1995-07-11
NO20004169D0 (no) 2000-08-21
NO943977L (no) 1994-10-20
IL105449A0 (en) 1993-08-18
KR950701221A (ko) 1995-03-23
WO1993020821A1 (en) 1993-10-28
DE69326459T2 (de) 2000-03-23
BG62154B1 (bg) 1999-04-30
UA27884C2 (uk) 2000-10-16
DK0637242T3 (da) 2000-03-27
DE69326459D1 (de) 1999-10-21
EE02974B1 (et) 1997-04-15
JP3245642B2 (ja) 2002-01-15
RO117150B1 (ro) 2001-11-30
EP0637242B1 (en) 1999-09-15
GR3032030T3 (en) 2000-03-31
SE9201239D0 (sv) 1992-04-21
CA2118512C (en) 2004-07-27
AU659941B2 (en) 1995-06-01
ZA932757B (en) 1993-10-28
HUT71420A (en) 1995-11-28
ES2139007T3 (es) 2000-02-01
HU223463B1 (hu) 2004-07-28
CZ281296B6 (cs) 1996-08-14
AU4043793A (en) 1993-11-18
PH31051A (en) 1998-02-03
CZ260694A3 (en) 1995-09-13
US5565455A (en) 1996-10-15

Similar Documents

Publication Publication Date Title
RU94041223A (ru) Средство для лечения мотонейроновых заболеваний
SE9802073D0 (sv) New use
GEP20002298B (en) Benzimidazole Derivatives, Method of Their Production, Pharmaceutical Composition Containing the Same and Method for Its Treatment
GEP20033131B (en) Azabicycloalkanes as CCR5 Modulators, Pharmaceutical Compositions Containing the Same and Their Use for Treatment and Prevention of Diseases Caused by CCR5 Activity
RU94045866A (ru) Применение бисфенилалкилпиперазинов для лечения расстройств, вызванных злоупотреблением веществами, способ лечения
ATE282418T1 (de) Orale verabreichung wirksamer mengen von hyaluronsäure
MY111260A (en) Pharmaceutical composition for the treatment of nicotine dependence
KR910019618A (ko) 발기부전증 치료용 제약 조성물
DE69733089D1 (de) Behandlung der osteoarthritis durch verabreichung von poly-n-acetyl-d-glucosamin
ATE15596T1 (de) Pharmazeutische mittel.
AU8188691A (en) The use of inositoltrisphosphate for the preparing of medicaments
RU95101385A (ru) Продукты, содержащие g-csf и tnf связующие протеина
KR950016760A (ko) 치질 치료제
RO117760B1 (ro) Metodă pentru tratamentul unei afecţiuni de neurotransmisie serotoninergică defectivă
EA199800717A1 (ru) Способ лечения заболеваний млекопитающих и цвиттерионная композиция
CA2156481A1 (en) 5-ht2 receptor antagonist compositions useful in treating venous conditions
ATE356637T1 (de) Supramolekulare komplexe enthaltende arzneimittel
KR920000326A (ko) 사람에 있어서 몰핀 및 동족체의 진통 효과에 대한 내성 발생을 방지하기 위한 gm₁모노시알로강글리오사이드 및 이의 내부 에스테르 유도체의 용도
ES2093246T3 (es) Compuestos de benzazepina terapeuticos.
KR960706341A (ko) 유기 인 콜린스테라아제 억제제에 의해 야기되는 중독의 예방 및 예비 치료를 위한 약제 제형(pharmaceutical formulation for preventing or pre-treating poisoning by organophosphoric cholinesterase inhibitors)
RU2209064C2 (ru) Новое применение в медицинских целях
RU98101105A (ru) Новое применение в медицинских целях
CA2394471A1 (en) External preparation for treating pruritus
KR900701278A (ko) 바이러스 감염 치료용 담즙산
RU94032792A (ru) Применение 5нтiа - антагонистов для прекращения использования табака