ES2093246T3 - Compuestos de benzazepina terapeuticos. - Google Patents
Compuestos de benzazepina terapeuticos.Info
- Publication number
- ES2093246T3 ES2093246T3 ES92901758T ES92901758T ES2093246T3 ES 2093246 T3 ES2093246 T3 ES 2093246T3 ES 92901758 T ES92901758 T ES 92901758T ES 92901758 T ES92901758 T ES 92901758T ES 2093246 T3 ES2093246 T3 ES 2093246T3
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- therapeutic
- formula
- neurological disorders
- benzazepine compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Abstract
SE PRESENTA UN METODO PARA EL TRATAMIENTO DE ENFERMEDADES NEUROLOGICAS, QUE COMPRENDE LA ADMINISTRACION A UN MAMIFERO DE UNA CANTIDAD EFECTIVA DE TRATAMIENTO DE UN COMPUESTO DE LA FORMULA I O DE LA FORMULA II, EN LAS QUE R1, R2, R3 Y R4 SE SELECCIONAN INDEPENDIENTEMENTE ENTRE: HIDROGENO (13C)PERFLUOROALQUIL, HALO, NITRO, Y CIANO; R5 ES UN GRUPO (15C)ALQUIL; O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO. TAMBIEN SE SUMINISTRAN COMPUESTOS Y COMPOSICIONES FARMACEUTICAS ADECUADAS PARA EL TRATAMIENTO DE ENFERMEDADES NEUROLOGICAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919100028A GB9100028D0 (en) | 1991-01-02 | 1991-01-02 | Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2093246T3 true ES2093246T3 (es) | 1996-12-16 |
Family
ID=10687882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92901758T Expired - Lifetime ES2093246T3 (es) | 1991-01-02 | 1991-12-30 | Compuestos de benzazepina terapeuticos. |
Country Status (22)
Country | Link |
---|---|
US (3) | US5254683A (es) |
EP (1) | EP0517876B1 (es) |
JP (1) | JP3034604B2 (es) |
KR (1) | KR100229049B1 (es) |
AT (1) | ATE144423T1 (es) |
AU (1) | AU650086B2 (es) |
CA (1) | CA2058593A1 (es) |
CZ (1) | CZ299292A3 (es) |
DE (1) | DE69122858T2 (es) |
DK (1) | DK0517876T3 (es) |
ES (1) | ES2093246T3 (es) |
FI (1) | FI104071B (es) |
GB (2) | GB9100028D0 (es) |
GR (1) | GR3021440T3 (es) |
HU (2) | HU212269B (es) |
IE (1) | IE920009A1 (es) |
IL (1) | IL100484A (es) |
NO (1) | NO300497B1 (es) |
NZ (1) | NZ241197A (es) |
PL (1) | PL166481B1 (es) |
WO (1) | WO1992011854A1 (es) |
ZA (1) | ZA9223B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9100028D0 (en) * | 1991-01-02 | 1991-02-20 | Ici Plc | Compounds |
GB9212308D0 (en) * | 1992-06-10 | 1992-07-22 | Ici Plc | Therapeutic compositions |
WO1994000124A1 (en) * | 1992-06-22 | 1994-01-06 | Eckard Weber | Glycine receptor antagonists and the use thereof |
US5834479A (en) * | 1993-03-05 | 1998-11-10 | Mayer; David J. | Method and composition for alleviating pain |
CA2115792C (en) | 1993-03-05 | 2005-11-01 | David J. Mayer | Method for the treatment of pain |
GB9311948D0 (en) * | 1993-06-10 | 1993-07-28 | Zeneca Ltd | Substituted nitrogen heterocycles |
US5801168A (en) * | 1994-06-09 | 1998-09-01 | Zeneca Limited | Substituted nitrogen heterocycles |
US5476933A (en) * | 1994-11-16 | 1995-12-19 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | Azepine synthesis via a diels-alder reaction |
JP4989830B2 (ja) * | 1999-07-21 | 2012-08-01 | サーントゥル ナシオナル ドゥ ラ ルシェルシュ シャーンティフィク | 脳によるグルタミン酸塩の放出に対して抑制効果を示す薬剤を製造するためのベータ−ナフトキノン誘導体の使用 |
FR2796552A1 (fr) | 1999-07-21 | 2001-01-26 | Centre Nat Rech Scient | Nouvelle utilisation de derives de la beta-naphtoquinone et de leurs sels pour la fabrication de medicaments exercant un effet inhibiteur sur la liberation de glutamate dans le cerveau |
JPWO2016199789A1 (ja) * | 2015-06-08 | 2018-03-29 | 国立大学法人名古屋大学 | トリフルオロメチル置換セミスクアレートの製造方法、トリフルオロメチル置換セミスクアレートを起点とするトリフルオロメチル化合物の製造方法及びトリフルオロメチル基含有化合物 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1340334A (en) * | 1970-07-06 | 1973-12-12 | Rees A H | Synthesis of benzazetropolones and hence of kynurenic acids |
CY1403A (en) * | 1981-08-11 | 1987-12-18 | Ciba Geigy Ag | Benzazepin-2-ones |
US4410520A (en) * | 1981-11-09 | 1983-10-18 | Ciba-Geigy Corporation | 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids |
US4473575A (en) * | 1982-07-19 | 1984-09-25 | Ciba-Geigy Corporation | 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids |
US4575503A (en) * | 1983-02-10 | 1986-03-11 | Ciba-Geigy Corporation | 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids |
US4477446A (en) * | 1983-07-01 | 1984-10-16 | Usv Pharmaceutical Corporation | 1-Benzazepines and their pharmaceutical uses |
DE3416695A1 (de) * | 1984-05-05 | 1985-11-07 | Bayer Ag, 5090 Leverkusen | Amidinohydrazone von tetralin-, chromon-, thiochromon- und tretrahydrochinolin-derivaten, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
KR0167349B1 (ko) * | 1989-10-20 | 1999-02-18 | 오스카 아끼히꼬 | 벤조헤테로 고리 화합물 |
GB9100028D0 (en) * | 1991-01-02 | 1991-02-20 | Ici Plc | Compounds |
WO1994000124A1 (en) * | 1992-06-22 | 1994-01-06 | Eckard Weber | Glycine receptor antagonists and the use thereof |
-
1991
- 1991-01-02 GB GB919100028A patent/GB9100028D0/en active Pending
- 1991-12-24 IL IL10048491A patent/IL100484A/xx not_active IP Right Cessation
- 1991-12-30 DE DE69122858T patent/DE69122858T2/de not_active Expired - Fee Related
- 1991-12-30 PL PL91295932A patent/PL166481B1/pl unknown
- 1991-12-30 HU HU9202618A patent/HU212269B/hu unknown
- 1991-12-30 DK DK92901758.0T patent/DK0517876T3/da active
- 1991-12-30 CA CA002058593A patent/CA2058593A1/en not_active Abandoned
- 1991-12-30 AT AT92901758T patent/ATE144423T1/de not_active IP Right Cessation
- 1991-12-30 WO PCT/GB1991/002326 patent/WO1992011854A1/en active IP Right Grant
- 1991-12-30 JP JP04502158A patent/JP3034604B2/ja not_active Expired - Fee Related
- 1991-12-30 GB GB9127498A patent/GB2251616B/en not_active Expired - Fee Related
- 1991-12-30 AU AU91340/91A patent/AU650086B2/en not_active Ceased
- 1991-12-30 KR KR1019920702119A patent/KR100229049B1/ko not_active IP Right Cessation
- 1991-12-30 EP EP92901758A patent/EP0517876B1/en not_active Expired - Lifetime
- 1991-12-30 ES ES92901758T patent/ES2093246T3/es not_active Expired - Lifetime
- 1991-12-31 US US07/816,327 patent/US5254683A/en not_active Expired - Fee Related
-
1992
- 1992-01-02 IE IE000992A patent/IE920009A1/en not_active IP Right Cessation
- 1992-01-02 ZA ZA9223A patent/ZA9223B/xx unknown
- 1992-01-06 NZ NZ241197A patent/NZ241197A/en unknown
- 1992-08-20 FI FI923759A patent/FI104071B/fi active
- 1992-09-01 NO NO923413A patent/NO300497B1/no not_active IP Right Cessation
- 1992-09-30 CZ CS922992A patent/CZ299292A3/cs unknown
-
1993
- 1993-07-23 US US08/096,795 patent/US5446039A/en not_active Expired - Lifetime
-
1995
- 1995-05-01 US US08/431,809 patent/US5541319A/en not_active Expired - Fee Related
- 1995-06-26 HU HU95P/P00441P patent/HU211466A9/hu unknown
-
1996
- 1996-10-24 GR GR960402536T patent/GR3021440T3/el unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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