DE69634360T2 - Methoden zur erhöhung der produktion von viralen impstoffen in zellkultur durch unterdrückung von interferon - Google Patents
Methoden zur erhöhung der produktion von viralen impstoffen in zellkultur durch unterdrückung von interferon Download PDFInfo
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- DE69634360T2 DE69634360T2 DE69634360T DE69634360T DE69634360T2 DE 69634360 T2 DE69634360 T2 DE 69634360T2 DE 69634360 T DE69634360 T DE 69634360T DE 69634360 T DE69634360 T DE 69634360T DE 69634360 T2 DE69634360 T2 DE 69634360T2
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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| US262195P | 1995-08-22 | 1995-08-22 | |
| US2621P | 1995-08-22 | ||
| PCT/US1996/013745 WO1997008292A1 (en) | 1995-08-22 | 1996-08-22 | Methods for enhancing the production of viral vaccines in cell culture by interferon suppression |
Publications (2)
| Publication Number | Publication Date |
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| DE69634360D1 DE69634360D1 (de) | 2005-03-24 |
| DE69634360T2 true DE69634360T2 (de) | 2005-12-29 |
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| DE69634360T Expired - Lifetime DE69634360T2 (de) | 1995-08-22 | 1996-08-22 | Methoden zur erhöhung der produktion von viralen impstoffen in zellkultur durch unterdrückung von interferon |
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| EP (2) | EP0846160B1 (enExample) |
| JP (2) | JP4267693B2 (enExample) |
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| DE (1) | DE69634360T2 (enExample) |
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| US5840565A (en) * | 1995-08-22 | 1998-11-24 | The Regents Of The University Of California | Methods for enhancing the production of viral vaccines in PKR-deficient cell culture |
| US6855519B2 (en) * | 1995-08-22 | 2005-02-15 | The Regents Of The University Of California | Methods for enhancing the production of interferon in cell culture |
| US6740519B1 (en) | 1997-11-03 | 2004-05-25 | Mount Sinai School Of Medicine | Immortalized, homozygous stat1-deficient mammalian cell lines and their uses |
| JP4837827B2 (ja) | 1998-06-12 | 2011-12-14 | マウント シナイ スクール オブ メディシン | 新規なウイルス増殖方法およびそのためのインターフェロン欠損培養基 |
| US6762038B1 (en) * | 1998-09-09 | 2004-07-13 | The Cleveland Clinic Foundation | Mutant cell lines and methods for producing enhanced levels of recombinant proteins |
| HK1048650A1 (zh) * | 1999-06-15 | 2003-04-11 | Genetrol Biotherapeutics | 在细胞培养物中增强细胞激动素(cytokines)的方法 |
| EP1067179A1 (en) * | 1999-07-09 | 2001-01-10 | Pierre Fabre Medicament | Method to select attenuated paramyxoviridae useful for vaccines and therapeutics |
| HK1048135A1 (zh) * | 1999-09-08 | 2003-03-21 | Genetrol Biotherapeutics | 具增强细胞活力功能的高产量的细胞变动素(cytokine) |
| US20010031859A1 (en) * | 1999-09-08 | 2001-10-18 | Lau Allan S. | High level cytokine production with enhanced cell viability |
| WO2001077394A1 (en) | 2000-04-10 | 2001-10-18 | Mount Sinai School Of Medicine Of New York University | Screening methods for identifying viral proteins with interferon antagonizing functions and potential antiviral agents |
| IL136232A0 (en) * | 2000-05-18 | 2001-05-20 | Bar Ilan University Res Author | Measurements of enzymatic activity in a single, individual cell in population |
| US6660471B2 (en) * | 2000-08-04 | 2003-12-09 | Chiron Corporation | Enhanced replication of HCV RNA |
| US20020150541A1 (en) * | 2000-09-12 | 2002-10-17 | Gene Trol Biotherapeutics, Inc. | Compositions comprising mixtures of therapeutic proteins and methods of producing the same |
| AU2001290855A1 (en) | 2000-09-14 | 2002-03-26 | Genetrol Biotherapeutics, Inc. | Method and cell composition for screening compounds for anti-inflammatory activity |
| AU2002251714A1 (en) * | 2000-12-19 | 2002-08-19 | Genetrol Biotherapeutics, Inc. | Cells with enhanced pkr expression for increasing cytokine production |
| DE10104094C1 (de) * | 2001-01-31 | 2002-07-25 | Angelika Vallbracht-Flehmig | Verfahren zur Erhöhung der Virusvermehrung und Virusausbeute in Zellkulturen, durch Blockade der RNaseL-Aktivierung |
| EP2332651A3 (en) * | 2001-10-25 | 2011-08-31 | Bar Ilan University | Interactive transparent individual cells biochip processor |
| IL154677A0 (en) * | 2003-02-27 | 2003-09-17 | Univ Bar Ilan | A method and apparatus for manipulating an individual cell |
| US7888110B2 (en) | 2003-06-26 | 2011-02-15 | Seng Enterprises Ltd. | Pico liter well holding device and method of making the same |
| WO2004113492A1 (en) * | 2003-06-26 | 2004-12-29 | Molecular Cytomics Ltd. | Improved materials for constructing cell-chips, cell-chip covers, cell-chip coats, processed cell-chips and uses thereof |
| US9200245B2 (en) | 2003-06-26 | 2015-12-01 | Seng Enterprises Ltd. | Multiwell plate |
| US8597597B2 (en) | 2003-06-26 | 2013-12-03 | Seng Enterprises Ltd. | Picoliter well holding device and method of making the same |
| WO2005008626A1 (en) * | 2003-07-11 | 2005-01-27 | University Of North Carolina At Chapel Hill | Methods and systems for controlling a computer using a video image and for combining the video image with a computer desktop |
| KR101280094B1 (ko) * | 2003-08-11 | 2013-06-28 | 사이단호진한다이비세이부쯔뵤우겐큐우카이 | 점막 면역을 유도할 수 있는 보강제를 함유한 신규한 백신 |
| US20050064524A1 (en) * | 2003-08-11 | 2005-03-24 | Mordechai Deutsch | Population of cells utilizable for substance detection and methods and devices using same |
| NZ591879A (en) * | 2003-10-23 | 2012-11-30 | Kineta Two Llc | Detection of mutations in a gene associated with resistance to viral infection, OAS1 |
| KR20060116825A (ko) | 2003-10-23 | 2006-11-15 | 일루미겐 바이오사이언시스, 인코포레이티드 | 바이러스 감염에 대한 저항성과 관련된 유전자인ｏａｓ1에서의 돌연변이의 검출 |
| CN103755800B (zh) | 2004-02-02 | 2016-02-24 | Ambrx公司 | 经修饰的人类生长激素多肽与其用途 |
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| US5840565A (en) * | 1995-08-22 | 1998-11-24 | The Regents Of The University Of California | Methods for enhancing the production of viral vaccines in PKR-deficient cell culture |
-
1996
- 1996-08-21 US US08/700,198 patent/US5840565A/en not_active Expired - Lifetime
- 1996-08-22 AU AU68576/96A patent/AU6857696A/en not_active Abandoned
- 1996-08-22 EP EP96929066A patent/EP0846160B1/en not_active Expired - Lifetime
- 1996-08-22 EP EP96929017A patent/EP0846174A4/en not_active Withdrawn
- 1996-08-22 CA CA002229405A patent/CA2229405C/en not_active Expired - Fee Related
- 1996-08-22 CN CNB961977515A patent/CN1161469C/zh not_active Expired - Fee Related
- 1996-08-22 WO PCT/US1996/013627 patent/WO1997008324A1/en not_active Ceased
- 1996-08-22 CA CA2229163A patent/CA2229163C/en not_active Expired - Lifetime
- 1996-08-22 DE DE69634360T patent/DE69634360T2/de not_active Expired - Lifetime
- 1996-08-22 AT AT96929066T patent/ATE289348T1/de active
- 1996-08-22 BR BR9610550A patent/BR9610550A/pt not_active Application Discontinuation
- 1996-08-22 JP JP51050897A patent/JP4267693B2/ja not_active Expired - Lifetime
- 1996-08-22 AU AU68608/96A patent/AU707130B2/en not_active Expired
- 1996-08-22 WO PCT/US1996/013745 patent/WO1997008292A1/en not_active Ceased
- 1996-08-22 JP JP51045097A patent/JP3432519B2/ja not_active Expired - Fee Related
-
1999
- 1999-11-19 US US09/444,224 patent/US6159712A/en not_active Expired - Fee Related
-
2000
- 2000-06-12 US US09/591,813 patent/US6489144B1/en not_active Expired - Fee Related
- 2000-12-13 US US09/736,748 patent/US6673591B2/en not_active Expired - Fee Related
- 2000-12-13 US US09/737,126 patent/US6686190B2/en not_active Expired - Lifetime
-
2003
- 2003-11-24 US US10/722,349 patent/US7132271B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0846160A1 (en) | 1998-06-10 |
| AU6860896A (en) | 1997-03-19 |
| CA2229405A1 (en) | 1997-03-06 |
| ATE289348T1 (de) | 2005-03-15 |
| US6159712A (en) | 2000-12-12 |
| CA2229163C (en) | 2011-04-05 |
| EP0846174A4 (en) | 2003-02-05 |
| US6686190B2 (en) | 2004-02-03 |
| EP0846160B1 (en) | 2005-02-16 |
| US7132271B2 (en) | 2006-11-07 |
| MX9801423A (es) | 1998-05-31 |
| BR9610550A (pt) | 1999-07-06 |
| JP3432519B2 (ja) | 2003-08-04 |
| US6489144B1 (en) | 2002-12-03 |
| US6673591B2 (en) | 2004-01-06 |
| AU707130B2 (en) | 1999-07-01 |
| AU6857696A (en) | 1997-03-19 |
| CA2229163A1 (en) | 1997-03-06 |
| US20010001709A1 (en) | 2001-05-24 |
| US20010001290A1 (en) | 2001-05-17 |
| DE69634360D1 (de) | 2005-03-24 |
| CN1161469C (zh) | 2004-08-11 |
| JPH11514344A (ja) | 1999-12-07 |
| JPH11511324A (ja) | 1999-10-05 |
| US5840565A (en) | 1998-11-24 |
| EP0846160A4 (en) | 2002-01-02 |
| CA2229405C (en) | 2004-03-02 |
| US20040157310A1 (en) | 2004-08-12 |
| JP4267693B2 (ja) | 2009-05-27 |
| EP0846174A1 (en) | 1998-06-10 |
| CN1200148A (zh) | 1998-11-25 |
| WO1997008324A1 (en) | 1997-03-06 |
| WO1997008292A1 (en) | 1997-03-06 |
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