DE69626387T2 - Antagonisten von humanem interleukin-6, welche zur bindung mit gp 130 unfähig sind und ihre verwendung in der herstellung von pharmazeutische zusammensetzungen - Google Patents
Antagonisten von humanem interleukin-6, welche zur bindung mit gp 130 unfähig sind und ihre verwendung in der herstellung von pharmazeutische zusammensetzungenInfo
- Publication number
- DE69626387T2 DE69626387T2 DE69626387T DE69626387T DE69626387T2 DE 69626387 T2 DE69626387 T2 DE 69626387T2 DE 69626387 T DE69626387 T DE 69626387T DE 69626387 T DE69626387 T DE 69626387T DE 69626387 T2 DE69626387 T2 DE 69626387T2
- Authority
- DE
- Germany
- Prior art keywords
- interleukin
- pct
- antagonists
- humanem
- bind
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5412—IL-6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT95RM000273A IT1276555B1 (it) | 1995-04-28 | 1995-04-28 | Antagonisti di interluchina-6 umana del tutto incapaci di formare un legame con gp 130, e loro uso per la preparazione di composizioni |
PCT/IT1996/000084 WO1996034104A1 (en) | 1995-04-28 | 1996-04-26 | Antagonists of human interleukin-6 that are totally incapable of binding gp 130, and their use in the preparation of pharmaceutical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69626387D1 DE69626387D1 (de) | 2003-04-03 |
DE69626387T2 true DE69626387T2 (de) | 2003-12-11 |
Family
ID=11403338
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69626387T Expired - Fee Related DE69626387T2 (de) | 1995-04-28 | 1996-04-26 | Antagonisten von humanem interleukin-6, welche zur bindung mit gp 130 unfähig sind und ihre verwendung in der herstellung von pharmazeutische zusammensetzungen |
Country Status (11)
Country | Link |
---|---|
US (1) | US5972902A (de) |
EP (1) | EP0822986B1 (de) |
JP (2) | JP3373856B2 (de) |
AT (1) | ATE233320T1 (de) |
CA (1) | CA2218372C (de) |
DE (1) | DE69626387T2 (de) |
DK (1) | DK0822986T3 (de) |
ES (1) | ES2191096T3 (de) |
IT (1) | IT1276555B1 (de) |
PT (1) | PT822986E (de) |
WO (1) | WO1996034104A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3824173B2 (ja) * | 1995-11-07 | 2006-09-20 | 株式会社カネカ | 自己抗原 |
WO1997029201A2 (de) * | 1996-02-07 | 1997-08-14 | Max-Delbrück-Centrum für Molekulare Medizin | Retroviraler vektor für den gentransfer eines il6-antagonisten in humane hämatopoetische stammzellen |
ATE547119T1 (de) | 1997-03-21 | 2012-03-15 | Chugai Pharmaceutical Co Ltd | Präventives oder therapeutisches mittel mit einem il-6-antagonisten als wirkstoff für durch sensibilisierte t-zellen vermittelte erkrankungen |
IT1291932B1 (it) * | 1997-06-20 | 1999-01-21 | Angeletti P Ist Richerche Bio | Composizioni farmaceutiche antitumorali capaci anche di ridurre la farmacoresistenza in cellule tumorali, in particolare di carcinoma |
KR100694005B1 (ko) | 2000-03-06 | 2007-03-12 | 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이. | 높은 아로마타제 수준을 특징으로 하는 질병의 치료를위한 인터류킨-6 길항물질의 용도 |
KR20100120246A (ko) * | 2001-11-14 | 2010-11-12 | 센토코 오르토 바이오테크 인코포레이티드 | 항 il-6 항체, 조성물, 방법 및 용도 |
US20050100550A1 (en) * | 2003-11-10 | 2005-05-12 | Mohit Trikha | Anti-angiogenic uses of IL-6 antagonists |
ITRM20050103A1 (it) * | 2005-03-10 | 2006-09-11 | Rocco Savino | Associazione di antagonisti della interleuchina 6 e farmaci antiproliferativi. |
PE20061324A1 (es) | 2005-04-29 | 2007-01-15 | Centocor Inc | Anticuerpos anti-il-6, composiciones, metodos y usos |
US8188235B2 (en) | 2008-06-18 | 2012-05-29 | Pfizer Inc. | Antibodies to IL-6 and their uses |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994009138A1 (en) * | 1992-10-20 | 1994-04-28 | Cetus Oncology Corporation | Interleukin-6 receptor antagonists |
IT1261787B (it) * | 1993-06-23 | 1996-06-03 | Angeletti P Ist Richerche Bio | Metodologia per la selezione di superagonisti, antagonisti e super- antagonisti di ormoni del cui complesso recettoriale fa parte gp 130. |
-
1995
- 1995-04-28 IT IT95RM000273A patent/IT1276555B1/it active IP Right Grant
-
1996
- 1996-04-26 EP EP96912205A patent/EP0822986B1/de not_active Expired - Lifetime
- 1996-04-26 ES ES96912205T patent/ES2191096T3/es not_active Expired - Lifetime
- 1996-04-26 DE DE69626387T patent/DE69626387T2/de not_active Expired - Fee Related
- 1996-04-26 DK DK96912205T patent/DK0822986T3/da active
- 1996-04-26 WO PCT/IT1996/000084 patent/WO1996034104A1/en active IP Right Grant
- 1996-04-26 US US08/945,529 patent/US5972902A/en not_active Expired - Fee Related
- 1996-04-26 PT PT96912205T patent/PT822986E/pt unknown
- 1996-04-26 JP JP53233396A patent/JP3373856B2/ja not_active Expired - Fee Related
- 1996-04-26 AT AT96912205T patent/ATE233320T1/de not_active IP Right Cessation
- 1996-04-26 CA CA002218372A patent/CA2218372C/en not_active Expired - Fee Related
-
2002
- 2002-09-05 JP JP2002259481A patent/JP2003153691A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ATE233320T1 (de) | 2003-03-15 |
DK0822986T3 (da) | 2003-04-28 |
ITRM950273A1 (it) | 1996-10-28 |
WO1996034104A1 (en) | 1996-10-31 |
ITRM950273A0 (it) | 1995-04-28 |
JPH10506538A (ja) | 1998-06-30 |
DE69626387D1 (de) | 2003-04-03 |
CA2218372A1 (en) | 1996-10-31 |
IT1276555B1 (it) | 1997-11-03 |
JP2003153691A (ja) | 2003-05-27 |
JP3373856B2 (ja) | 2003-02-04 |
EP0822986B1 (de) | 2003-02-26 |
EP0822986A1 (de) | 1998-02-11 |
ES2191096T3 (es) | 2003-09-01 |
US5972902A (en) | 1999-10-26 |
PT822986E (pt) | 2003-07-31 |
CA2218372C (en) | 2001-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |