ATE360032T1 - Cystein-reiche rezeptoren-train - Google Patents

Cystein-reiche rezeptoren-train

Info

Publication number
ATE360032T1
ATE360032T1 AT98944859T AT98944859T ATE360032T1 AT E360032 T1 ATE360032 T1 AT E360032T1 AT 98944859 T AT98944859 T AT 98944859T AT 98944859 T AT98944859 T AT 98944859T AT E360032 T1 ATE360032 T1 AT E360032T1
Authority
AT
Austria
Prior art keywords
train
cystein
receptor
rich receptor
rich
Prior art date
Application number
AT98944859T
Other languages
English (en)
Inventor
Jurg Tschopp
Catherine Hession
Original Assignee
Biogen Idec Inc
Apotech R & D Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Inc, Apotech R & D Sa filed Critical Biogen Idec Inc
Application granted granted Critical
Publication of ATE360032T1 publication Critical patent/ATE360032T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153 or CD154
AT98944859T 1997-09-12 1998-09-11 Cystein-reiche rezeptoren-train ATE360032T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5863197P 1997-09-12 1997-09-12
US8442298P 1998-05-06 1998-05-06

Publications (1)

Publication Number Publication Date
ATE360032T1 true ATE360032T1 (de) 2007-05-15

Family

ID=26737837

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98944859T ATE360032T1 (de) 1997-09-12 1998-09-11 Cystein-reiche rezeptoren-train

Country Status (10)

Country Link
US (4) US7223852B2 (de)
EP (2) EP1012179A2 (de)
JP (1) JP4357738B2 (de)
AT (1) ATE360032T1 (de)
AU (2) AU738688B2 (de)
CA (1) CA2301173C (de)
DE (1) DE69837606T2 (de)
ES (1) ES2286856T3 (de)
HK (1) HK1028417A1 (de)
WO (2) WO1999013078A1 (de)

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US7528239B1 (en) 1997-02-13 2009-05-05 Immunex Corporation Receptor that binds trail
US6072047A (en) 1997-02-13 2000-06-06 Immunex Corporation Receptor that binds trail
DK0990703T3 (da) * 1997-02-27 2008-09-29 Ono Pharmaceutical Co Nyt polypeptid, DNA, som koder herfor, samt anvendelse heraf
US6342369B1 (en) 1997-05-15 2002-01-29 Genentech, Inc. Apo-2-receptor
EP1012179A2 (de) 1997-09-12 2000-06-28 Apotech R&D S.A. Cystein-reiche rezeptoren: trail
AU748167B2 (en) * 1997-12-29 2002-05-30 Regeneron Pharmaceuticals, Inc. Novel nucleic acid and polypeptide
AU2472899A (en) * 1998-01-27 1999-08-09 Millennium Pharmaceuticals, Inc. Novel molecules of the tnf receptor superfamily and uses therefor
AU2486300A (en) * 1998-12-30 2000-07-31 Millennium Pharmaceuticals, Inc. Secreted proteins and nucleic acids encoding them
AU2574200A (en) * 1999-02-19 2000-09-04 Toshio Kitamura Novel tnf receptor-like proteins
RS51157B (sr) 1999-08-17 2010-10-31 Biogen Idec Ma Inc. Baff receptor (bcma), imunoregulatorni agens
CA2382101A1 (en) * 1999-08-25 2001-03-01 Genome Therapeutics Corporation A transmembrane trap for isolating membrane bound proteins
EP1237921A1 (de) 1999-10-22 2002-09-11 ZymoGenetics, Inc. Umlr-polypeptide
GB9927681D0 (en) * 1999-11-23 2000-01-19 Glaxo Group Ltd Protein
WO2001058954A2 (en) * 2000-02-11 2001-08-16 Genetics Institute, Llc. Trade molecules and uses related thereto
US6900185B1 (en) 2000-04-12 2005-05-31 University Of Iowa Research Foundation Method of inducing tumor cell apoptosis using trail/Apo-2 ligand gene transfer
TWI318983B (en) 2000-05-02 2010-01-01 Uab Research Foundation An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof
US7279160B2 (en) 2000-05-02 2007-10-09 The Uab Research Foundation Combinations of DR5 antibodies and other therapeutic agents
US7476383B2 (en) 2000-05-02 2009-01-13 The Uab Research Foundation Antibody selective for DR4 and uses thereof
CA2426710A1 (en) * 2000-11-08 2002-10-10 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to trail receptors
MXPA03010747A (es) 2001-05-25 2004-03-02 Human Genome Sciences Inc Anticuerpos que se unen inmunoespecificamente a receptores de ligando inductor de apoptosis relacionado con factor de necrosis tumoral.
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
KR20060132006A (ko) 2004-03-23 2006-12-20 비오겐 아이덱 엠에이 아이엔씨. 수용체 커플링제 및 이의 치료적 용도
EP1789070B1 (de) 2004-08-03 2012-10-24 Biogen Idec MA Inc. Taj in der neuronalen funktion
AU2006210838B2 (en) 2005-02-02 2011-10-20 The Uab Research Foundation Agents and methods related to reducing resistance to apoptosis-inducing death receptor agonists
JP4898126B2 (ja) * 2005-02-28 2012-03-14 中外製薬株式会社 Ｔｒｏｙシグナルが阻害されたトランスジェニック非ヒト動物
PE20071101A1 (es) 2005-08-31 2007-12-21 Amgen Inc Polipeptidos y anticuerpos
EP2010917B1 (de) * 2006-04-10 2012-06-27 Trustees of Boston University Melanom-biomarker und verwendungsverfahren dafür
KR20120101050A (ko) 2009-11-05 2012-09-12 더 유에이비 리서치 파운데이션 기저형 유전자형 암의 치료 방법
WO2011116344A2 (en) 2010-03-18 2011-09-22 The Uab Research Foundation Targeting cancer stem cells
RS54846B1 (sr) 2010-10-29 2016-10-31 Daiichi Sankyo Co Ltd Novo anti-dr5 antitelo
WO2012142502A2 (en) 2011-04-15 2012-10-18 Dexcom Inc. Advanced analyte sensor calibration and error detection
US9433376B2 (en) 2012-03-16 2016-09-06 Dexcom, Inc. Systems and methods for processing analyte sensor data
CN212438615U (zh) 2017-10-24 2021-02-02 德克斯康公司 可穿戴设备
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors

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Publication number Priority date Publication date Assignee Title
US5225538A (en) 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
US5965388A (en) 1996-07-09 1999-10-12 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO2002008288A2 (en) 2000-07-20 2002-01-31 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP0990031B1 (de) * 1997-01-14 2006-03-29 Human Genome Sciences, Inc. Tumor-nekrose-faktor rezeptor 5
US6072047A (en) * 1997-02-13 2000-06-06 Immunex Corporation Receptor that binds trail
DK0990703T3 (da) * 1997-02-27 2008-09-29 Ono Pharmaceutical Co Nyt polypeptid, DNA, som koder herfor, samt anvendelse heraf
CA2644454A1 (en) * 1997-03-17 1998-09-24 Human Genome Sciences, Inc. Death domain containing receptor 5
WO1999011791A2 (en) 1997-09-05 1999-03-11 University Of Washington Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
EP1012179A2 (de) * 1997-09-12 2000-06-28 Apotech R&D S.A. Cystein-reiche rezeptoren: trail
US20030027272A1 (en) * 1997-09-18 2003-02-06 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA2306457A1 (en) 1997-10-18 1999-04-29 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
AU748167B2 (en) 1997-12-29 2002-05-30 Regeneron Pharmaceuticals, Inc. Novel nucleic acid and polypeptide
AU2093499A (en) 1997-12-30 1999-07-19 Chiron Corporation Members of tnf and tnfr families
AU2472899A (en) 1998-01-27 1999-08-09 Millennium Pharmaceuticals, Inc. Novel molecules of the tnf receptor superfamily and uses therefor
CA2332573A1 (en) 1998-07-06 2000-01-13 Elizabeth Esther Mary Bates Mammalian genes; dendritic cell prostaglandin-like transponder (dc-pgt), hdtea84, hsljd37r and rankl, hcc5 chemokine, deubiquitinating 11 and 12 (dub11, dub12), md-1, md2 and cyclin e2, related reagents and methods
JP2000098232A (ja) * 1998-09-25 2000-04-07 Canon Inc 光学素子及びそれを用いた光学系
AU2574200A (en) 1999-02-19 2000-09-04 Toshio Kitamura Novel tnf receptor-like proteins
EP1220905A2 (de) 1999-03-08 2002-07-10 Genentech Inc. Zusammensetzung und verfahren zur behandlung von immunverwandten krankheiten
GB9927681D0 (en) 1999-11-23 2000-01-19 Glaxo Group Ltd Protein
WO2001058954A2 (en) 2000-02-11 2001-08-16 Genetics Institute, Llc. Trade molecules and uses related thereto
AU6802801A (en) 2000-03-01 2001-09-24 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU6531101A (en) 2000-06-02 2001-12-17 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP2004506413A (ja) 2000-06-23 2004-03-04 ジェネンテック・インコーポレーテッド 血管形成に関与する疾患の診断と治療のための組成物と方法
CA2416538A1 (en) 2000-07-20 2002-01-31 Genentech, Inc. Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
AU2002328173A1 (en) 2001-08-07 2003-02-24 Genset S.A. Omoxin agonists and antagonists for use in the treatment of metabolic disorders
US8067664B2 (en) 2003-12-16 2011-11-29 Genentech, Inc. PRO224 gene disruptions, and methods related thereto
EP1789070B1 (de) 2004-08-03 2012-10-24 Biogen Idec MA Inc. Taj in der neuronalen funktion
WO2007092777A2 (en) * 2006-02-02 2007-08-16 Wyeth Cloning, characterization, and application of tnfrsf19 in neurological disorders

Also Published As

Publication number Publication date
US20090004188A1 (en) 2009-01-01
EP1012179A2 (de) 2000-06-28
EP1012282B1 (de) 2007-04-18
CA2301173C (en) 2015-04-14
DE69837606T2 (de) 2008-02-14
DE69837606D1 (de) 2007-05-31
WO1999012963A3 (en) 1999-05-06
US20060233792A1 (en) 2006-10-19
EP1012282A1 (de) 2000-06-28
WO1999012963A2 (en) 1999-03-18
AU9386398A (en) 1999-03-29
AU738688B2 (en) 2001-09-27
JP2002505843A (ja) 2002-02-26
CA2301173A1 (en) 1999-03-18
WO1999013078A1 (en) 1999-03-18
ES2286856T3 (es) 2007-12-01
AU9230398A (en) 1999-03-29
US7838639B2 (en) 2010-11-23
US7402658B2 (en) 2008-07-22
US7223852B2 (en) 2007-05-29
JP4357738B2 (ja) 2009-11-04
US20030219860A1 (en) 2003-11-27
US20110158993A1 (en) 2011-06-30
HK1028417A1 (en) 2001-02-16

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