DE69630457T2 - Verbindungen zur immunotherapie und diagnose von tuberkulose - Google Patents

Verbindungen zur immunotherapie und diagnose von tuberkulose Download PDF

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Publication number
DE69630457T2
DE69630457T2 DE69630457T DE69630457T DE69630457T2 DE 69630457 T2 DE69630457 T2 DE 69630457T2 DE 69630457 T DE69630457 T DE 69630457T DE 69630457 T DE69630457 T DE 69630457T DE 69630457 T2 DE69630457 T2 DE 69630457T2
Authority
DE
Germany
Prior art keywords
seq
tuberculosis
ala
pro
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69630457T
Other languages
German (de)
English (en)
Other versions
DE69630457D1 (de
Inventor
G. Steven REED
A. Yasir SKEIKY
C. Davin DILLON
Antonio Campos-Neto
Raymond Houghton
H. Thomas VEDVICK
R. Daniel TWARDZIK
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corixa Corp
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27541835&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69630457(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Corixa Corp filed Critical Corixa Corp
Application granted granted Critical
Publication of DE69630457D1 publication Critical patent/DE69630457D1/de
Publication of DE69630457T2 publication Critical patent/DE69630457T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69630457T 1995-09-01 1996-08-30 Verbindungen zur immunotherapie und diagnose von tuberkulose Expired - Lifetime DE69630457T2 (de)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US52343695A 1995-09-01 1995-09-01
US523436 1995-09-01
US53363495A 1995-09-22 1995-09-22
US533634 1995-09-22
US62087496A 1996-03-22 1996-03-22
US620874 1996-03-22
US65968396A 1996-06-05 1996-06-05
US659683 1996-06-05
US68057496A 1996-07-12 1996-07-12
US680574 1996-07-12
PCT/US1996/014674 WO1997009428A2 (en) 1995-09-01 1996-08-30 Compounds and methods for immunotherapy and diagnosis of tuberculosis

Publications (2)

Publication Number Publication Date
DE69630457D1 DE69630457D1 (de) 2003-11-27
DE69630457T2 true DE69630457T2 (de) 2004-11-25

Family

ID=27541835

Family Applications (4)

Application Number Title Priority Date Filing Date
DE69636046T Expired - Lifetime DE69636046T2 (de) 1995-09-01 1996-08-30 Verbindungen und Verfahren zur Immuntherapie und Diagnose von Tuberkulose
DE69637879T Expired - Lifetime DE69637879D1 (de) 1995-09-01 1996-08-30 Verbindungen und Verfahren zur Immuntherapie und Diagnose von Tuberkulose
DE69630457T Expired - Lifetime DE69630457T2 (de) 1995-09-01 1996-08-30 Verbindungen zur immunotherapie und diagnose von tuberkulose
DE69636487T Expired - Lifetime DE69636487T2 (de) 1995-09-01 1996-08-30 Zusammensetzungen zur Immuntherapie und Diagnose von Tuberculosis

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE69636046T Expired - Lifetime DE69636046T2 (de) 1995-09-01 1996-08-30 Verbindungen und Verfahren zur Immuntherapie und Diagnose von Tuberkulose
DE69637879T Expired - Lifetime DE69637879D1 (de) 1995-09-01 1996-08-30 Verbindungen und Verfahren zur Immuntherapie und Diagnose von Tuberkulose

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69636487T Expired - Lifetime DE69636487T2 (de) 1995-09-01 1996-08-30 Zusammensetzungen zur Immuntherapie und Diagnose von Tuberculosis

Country Status (23)

Country Link
EP (5) EP1347055B1 (enExample)
JP (5) JP4382160B2 (enExample)
KR (1) KR100433750B1 (enExample)
CN (1) CN1117149C (enExample)
AT (5) ATE513915T1 (enExample)
AU (1) AU727602B2 (enExample)
BR (2) BR9610262B1 (enExample)
CA (3) CA2653566C (enExample)
CY (2) CY2570B1 (enExample)
CZ (3) CZ300688B6 (enExample)
DE (4) DE69636046T2 (enExample)
DK (4) DK1398379T3 (enExample)
ES (4) ES2210392T3 (enExample)
HU (2) HU225979B1 (enExample)
IL (1) IL123506A (enExample)
MX (1) MX9801638A (enExample)
NO (4) NO324372B1 (enExample)
NZ (1) NZ319377A (enExample)
PL (1) PL186774B1 (enExample)
PT (4) PT1203817E (enExample)
SI (1) SI0851927T1 (enExample)
TR (5) TR200806259T2 (enExample)
WO (1) WO1997009428A2 (enExample)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2501135Y2 (ja) 1989-06-10 1996-06-12 エヌティエヌ株式会社 摩擦式無段変速機
JP2501911B2 (ja) 1989-08-15 1996-05-29 日産自動車株式会社 トロイダル型無段変速機
US6991797B2 (en) 1993-07-02 2006-01-31 Statens Serum Institut M. tuberculosis antigens
US6641814B1 (en) 1997-04-02 2003-11-04 Statens Serum Institut Nucleic acids fragments and polypeptide fragments derived from M. tuberculosis
US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
US6290969B1 (en) * 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
US6592877B1 (en) 1995-09-01 2003-07-15 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
IL129389A0 (en) * 1996-10-11 2000-02-17 Corixa Corp Compounds and methods for diagnsosis of tuberculosis
US6627198B2 (en) 1997-03-13 2003-09-30 Corixa Corporation Fusion proteins of Mycobacterium tuberculosis antigens and their uses
US6350456B1 (en) 1997-03-13 2002-02-26 Corixa Corporation Compositions and methods for the prevention and treatment of M. tuberculosis infection
US6544522B1 (en) * 1998-12-30 2003-04-08 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
ES2291810T3 (es) * 1997-04-02 2008-03-01 Statens Serum Institut Fragmentos de acido nucleico y fragmentos de polpeptidos derivados de m. tuberculosis.
US6982085B2 (en) 1997-04-02 2006-01-03 Statens Serum Institut TB diagnostic based on antigens from M. tuberculosis
US7037510B2 (en) 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
US6613881B1 (en) * 1997-05-20 2003-09-02 Corixa Corporation Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use
US6555653B2 (en) 1997-05-20 2003-04-29 Corixa Corporation Compounds for diagnosis of tuberculosis and methods for their use
EP1003870A1 (en) * 1997-07-16 2000-05-31 Institut Pasteur A polynucleotide functionally coding for the lhp protein from mycobacterium tuberculosis, its biologically active derivative fragments, as well as methods using the same
EP1484405A1 (en) * 1997-11-10 2004-12-08 Statens Serum Institut Nucleic acid fragments and polypeptide fragments derived from M. Tuberculosis
WO1999024577A1 (en) * 1997-11-10 1999-05-20 Statens Serum Institut NUCLEIC ACID FRAGMENTS AND POLYPEPTIDE FRAGMENTS DERIVED FROM $i(M. TUBERCULOSIS)
WO1999051748A2 (en) * 1998-04-07 1999-10-14 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
GB9808720D0 (en) * 1998-04-23 1998-06-24 Smithkline Beecham Biolog Novel compounds
CN1350546A (zh) * 1998-11-04 2002-05-22 Isis创新有限公司 结核诊断测验
AU2594500A (en) * 1998-12-24 2000-07-31 Corixa Corporation Methods for using mycobacterium tuberculosis molecules as immunological adjuvants
US6465633B1 (en) 1998-12-24 2002-10-15 Corixa Corporation Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis
DK1214088T3 (da) 1999-05-04 2009-08-24 Univ New Jersey Med Proteiner udtrykt af Mycobacterium tuberculosis og ikke af BCG og anvendelse heraf som diagnostiske reagenser og vacciner
US7009042B1 (en) * 1999-10-07 2006-03-07 Corixa Corporation Methods of using a Mycobacterium tuberculosis coding sequence to facilitate stable and high yield expression of the heterologous proteins
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
AU2001241738A1 (en) 2000-02-25 2001-09-03 Corixa Corporation Compounds and methods for diagnosis and immunotherapy of tuberculosis
AU6867801A (en) 2000-06-20 2002-01-02 Corixa Corp Fusion proteins of mycobacterium tuberculosis
WO2003070187A2 (en) 2002-02-15 2003-08-28 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
ITRM20040091A1 (it) 2004-02-19 2004-05-19 Istituto Naz Per Le Malattie Test immunologico rapido per la diagnosi ed il monitoraggio dell'infezione tubercolare.
FI119445B (fi) * 2004-10-29 2008-11-14 Waertsilae Finland Oy Polttomoottorin polttoaineen syöttöjärjestelmän paineen värähtelyn vaimennin
NZ555907A (en) 2004-11-16 2009-12-24 Aeras Global Tb Vaccine Found Multivalent vaccines comprising recombinant viral vectors
PL2457926T3 (pl) 2005-04-29 2015-03-31 Glaxosmithkline Biologicals Sa Nowy sposób profilaktyki lub leczenia zakażenia m. tuberculosis
FR2952058B1 (fr) * 2009-10-29 2013-10-04 Centre Nat Rech Scient Procede de ligation native de polypeptides
PL2528621T3 (pl) 2010-01-27 2017-07-31 Glaxosmithkline Biologicals S.A. Zmodyfikowane antygeny gruźlicy
HUE028452T2 (en) 2010-12-14 2016-12-28 Glaxosmithkline Biologicals Sa Mycobacterium antigenic preparations
FR2971509B1 (fr) * 2011-02-16 2013-02-22 Centre Nat Rech Scient Procede de preparation de peptides par assemblage de multiples fragments peptidiques
CN103290030A (zh) * 2012-02-23 2013-09-11 上海交通大学 一种结核分枝杆菌标志物HtdY的重组蛋白及其制备方法和临床应用
NZ701324A (en) * 2012-05-04 2016-09-30 Pfizer Prostate-associated antigens and vaccine-based immunotherapy regimens
CN111233992B (zh) * 2014-04-04 2024-07-19 韦斯塔隆公司 人工活化的肽
GB201513176D0 (en) 2015-07-27 2015-09-09 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response
FR3048286B1 (fr) * 2016-02-26 2021-01-22 Omunis Peptides immunogenes et leur utilisation
CN107304231B (zh) * 2016-04-18 2021-01-01 华中农业大学 一种结核分枝杆菌融合蛋白及应用
GB201614485D0 (en) * 2016-08-25 2016-10-12 Univ Oxford Innovation Ltd Immunogenic composition

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FR2244539A1 (en) * 1973-07-13 1975-04-18 Mitsui Pharmaceuticals Tuberculin active proteins and peptides prepn - from tubercle bacillus
FR2265402A1 (en) * 1974-03-29 1975-10-24 Mitsui Pharmaceuticals Tuberculin active proteins and peptides prepn - from tubercle bacillus
US4876089A (en) * 1984-09-06 1989-10-24 Chiron Corporation Feline leukemia virus protein vaccines
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US5075109A (en) 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US4897268A (en) 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
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US5330754A (en) * 1992-06-29 1994-07-19 Archana Kapoor Membrane-associated immunogens of mycobacteria
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DK79893D0 (da) * 1993-07-02 1993-07-02 Statens Seruminstitut New vaccine

Also Published As

Publication number Publication date
DK0851927T3 (da) 2004-01-26
ES2262595T3 (es) 2006-12-01
CN1117149C (zh) 2003-08-06
CA2230885A1 (en) 1997-03-13
EP1203817A2 (en) 2002-05-08
ATE323165T1 (de) 2006-04-15
JP4324596B2 (ja) 2009-09-02
ATE252640T1 (de) 2003-11-15
CZ300688B6 (cs) 2009-07-15
CY2612B2 (en) 2010-12-22
JP2009159982A (ja) 2009-07-23
PT1398379E (pt) 2007-01-31
WO1997009428A3 (en) 1997-07-17
CZ300953B6 (cs) 2009-09-23
NO324372B1 (no) 2007-10-01
BR9610262A (pt) 1999-07-06
PL325373A1 (en) 1998-07-20
NO336288B1 (no) 2015-07-13
EP1398379B1 (en) 2006-08-23
AU7158696A (en) 1997-03-27
DK1398379T3 (da) 2007-01-08
HK1059282A1 (en) 2004-06-25
DK1203817T3 (da) 2006-08-14
TR199800411T1 (xx) 1998-05-21
PL186774B1 (pl) 2004-02-27
EP1347055A2 (en) 2003-09-24
TR200901109T1 (tr) 2012-02-21
ES2324529T3 (es) 2009-08-10
HU227778B1 (en) 2012-02-28
CZ62898A3 (cs) 1999-10-13
DK1347055T3 (da) 2009-06-29
KR19990044347A (ko) 1999-06-25
HUP9900902A3 (en) 2001-03-28
JP4324618B2 (ja) 2009-09-02
ATE426025T1 (de) 2009-04-15
EP1203817A3 (en) 2003-01-29
CY2570B1 (en) 2008-07-02
CA2653566A1 (en) 1997-03-13
NO980883L (no) 1998-04-27
SI0851927T1 (en) 2004-02-29
CA2653566C (en) 2013-06-25
ATE513915T1 (de) 2011-07-15
EP1712628A3 (en) 2007-05-23
EP1712628A2 (en) 2006-10-18
HUP9900902A2 (hu) 1999-07-28
JP2006187292A (ja) 2006-07-20
PT1347055E (pt) 2009-06-19
MX9801638A (es) 1998-05-31
IL123506A (en) 2004-12-15
NO980883D0 (no) 1998-02-27
ES2210392T3 (es) 2004-07-01
CA2230885C (en) 2010-02-02
TR200403064T2 (tr) 2005-08-22
JP2001517069A (ja) 2001-10-02
NZ319377A (en) 2000-01-28
EP1203817B1 (en) 2006-04-12
TR200806258T2 (tr) 2008-10-21
CZ297406B6 (cs) 2006-12-13
CN1200147A (zh) 1998-11-25
EP0851927A2 (en) 1998-07-08
EP1347055A3 (en) 2003-11-26
EP1712628B1 (en) 2011-06-22
JP2006149406A (ja) 2006-06-15
NO20070618L (no) 1998-04-27
EP1398379A3 (en) 2004-07-14
ATE337399T1 (de) 2006-09-15
BR9612997B1 (pt) 2012-01-10
EP1203817B9 (en) 2006-08-16
JP4324597B2 (ja) 2009-09-02
DE69630457D1 (de) 2003-11-27
DE69637879D1 (de) 2009-04-30
JP4382160B2 (ja) 2009-12-09
DE69636487D1 (de) 2006-10-05
WO1997009428A2 (en) 1997-03-13
HU225979B1 (en) 2008-02-28
CA2684425A1 (en) 1997-03-13
EP0851927B1 (en) 2003-10-22
NO20070621L (no) 1998-04-27
DE69636046T2 (de) 2006-11-23
KR100433750B1 (ko) 2004-09-01
DE69636487T2 (de) 2007-05-03
ES2271449T3 (es) 2007-04-16
JP2007228972A (ja) 2007-09-13
PT1203817E (pt) 2006-08-31
BR9610262B1 (pt) 2013-11-26
AU727602B2 (en) 2000-12-14
NO20070619L (no) 1998-04-27
PT851927E (pt) 2004-03-31
EP1347055B1 (en) 2009-03-18
DE69636046D1 (de) 2006-05-24
EP1398379A2 (en) 2004-03-17
IL123506A0 (en) 1998-10-30
TR200806259T2 (tr) 2008-10-21

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