FR3048286B1 - Peptides immunogenes et leur utilisation - Google Patents
Peptides immunogenes et leur utilisation Download PDFInfo
- Publication number
- FR3048286B1 FR3048286B1 FR1651610A FR1651610A FR3048286B1 FR 3048286 B1 FR3048286 B1 FR 3048286B1 FR 1651610 A FR1651610 A FR 1651610A FR 1651610 A FR1651610 A FR 1651610A FR 3048286 B1 FR3048286 B1 FR 3048286B1
- Authority
- FR
- France
- Prior art keywords
- peptides
- value
- formation
- ratio
- serum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 230000002163 immunogen Effects 0.000 title abstract 2
- 201000008827 tuberculosis Diseases 0.000 abstract 3
- 208000036981 active tuberculosis Diseases 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 210000002966 serum Anatomy 0.000 abstract 2
- 239000013068 control sample Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/5695—Mycobacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/35—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
L'invention concerne une méthode de criblage in vitro de peptides immunogènes d'intérêt capables de reconnaitre des anticorps issus du sérum d'individus atteints de tuberculose active, ladite méthode comprenant : - la mise en contact de peptides du sérum issu de patients atteints de tuberculose active - la détection de la formation de complexes immuns à l'étape précédente, et - la sélection des peptides d'intérêt pour lesquels la valeur d'un ratio R est supérieure ou égale à 1,5, le ratio R étant la valeur de mesure de la formation de complexe immun sur la valeur de mesure obtenu à partir de l'échantillon contrôle.
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1651610A FR3048286B1 (fr) | 2016-02-26 | 2016-02-26 | Peptides immunogenes et leur utilisation |
EP17712193.6A EP3420358A1 (fr) | 2016-02-26 | 2017-02-24 | Peptides immunogenes et leur utilisation |
CN201780013116.0A CN108885213A (zh) | 2016-02-26 | 2017-02-24 | 免疫原性肽和其用途 |
US16/079,629 US20210199657A1 (en) | 2016-02-26 | 2017-02-24 | Immunogenic peptides and use thereof |
PCT/FR2017/050418 WO2017144830A1 (fr) | 2016-02-26 | 2017-02-24 | Peptides immunogenes et leur utilisation |
JP2018544825A JP2019511708A (ja) | 2016-02-26 | 2017-02-24 | 免疫原性ペプチド及びその使用 |
CA3014034A CA3014034A1 (fr) | 2016-02-26 | 2017-02-24 | Peptides immunogenes et leur utilisation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1651610A FR3048286B1 (fr) | 2016-02-26 | 2016-02-26 | Peptides immunogenes et leur utilisation |
Publications (2)
Publication Number | Publication Date |
---|---|
FR3048286A1 FR3048286A1 (fr) | 2017-09-01 |
FR3048286B1 true FR3048286B1 (fr) | 2021-01-22 |
Family
ID=56263826
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1651610A Active FR3048286B1 (fr) | 2016-02-26 | 2016-02-26 | Peptides immunogenes et leur utilisation |
Country Status (7)
Country | Link |
---|---|
US (1) | US20210199657A1 (fr) |
EP (1) | EP3420358A1 (fr) |
JP (1) | JP2019511708A (fr) |
CN (1) | CN108885213A (fr) |
CA (1) | CA3014034A1 (fr) |
FR (1) | FR3048286B1 (fr) |
WO (1) | WO2017144830A1 (fr) |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6290969B1 (en) * | 1995-09-01 | 2001-09-18 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
TR200806258T2 (tr) * | 1995-09-01 | 2008-10-21 | Corixa Corporation | Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler |
CA2758124A1 (fr) * | 2008-04-19 | 2009-10-22 | New York University | Peptide de mycobacterium tuberculosis immunodominants provenant de proteines de paroi cellulaire pour un diagnostic precoce et une immunisation |
US20110268744A1 (en) * | 2008-05-26 | 2011-11-03 | Ian Garthwaite | Method of Diagnosis of Infection by Mycobacteria and Reagents Therefor |
WO2011119484A1 (fr) * | 2010-03-23 | 2011-09-29 | Iogenetics, Llc | Procédés bioinformatiques pour déterminer la liaison de peptides |
WO2013040142A2 (fr) * | 2011-09-16 | 2013-03-21 | Iogenetics, Llc | Procédés bio-informatiques de détermination de liaisons peptidiques |
CN102297968B (zh) * | 2010-06-28 | 2013-10-30 | 程小星 | 辅助诊断结核病的试剂盒 |
US9274110B2 (en) * | 2011-06-03 | 2016-03-01 | Universite Montpellier 2 Sciences Et Technique | Diagnosis method of active tuberculosis |
JP6317993B2 (ja) * | 2014-05-07 | 2018-04-25 | ポーラ化成工業株式会社 | 肌改善剤のスクリーニング方法 |
CN104020297B (zh) * | 2014-06-10 | 2016-12-07 | 上海交通大学医学院 | 用于结核分枝杆菌感染检测及临床治疗效果监测的试剂盒及其用途 |
-
2016
- 2016-02-26 FR FR1651610A patent/FR3048286B1/fr active Active
-
2017
- 2017-02-24 US US16/079,629 patent/US20210199657A1/en not_active Abandoned
- 2017-02-24 WO PCT/FR2017/050418 patent/WO2017144830A1/fr active Application Filing
- 2017-02-24 CN CN201780013116.0A patent/CN108885213A/zh active Pending
- 2017-02-24 JP JP2018544825A patent/JP2019511708A/ja active Pending
- 2017-02-24 EP EP17712193.6A patent/EP3420358A1/fr not_active Withdrawn
- 2017-02-24 CA CA3014034A patent/CA3014034A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP3420358A1 (fr) | 2019-01-02 |
CN108885213A (zh) | 2018-11-23 |
CA3014034A1 (fr) | 2017-08-31 |
JP2019511708A (ja) | 2019-04-25 |
FR3048286A1 (fr) | 2017-09-01 |
WO2017144830A1 (fr) | 2017-08-31 |
US20210199657A1 (en) | 2021-07-01 |
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Legal Events
Date | Code | Title | Description |
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PLFP | Fee payment |
Year of fee payment: 2 |
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PLSC | Publication of the preliminary search report |
Effective date: 20170901 |
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PLFP | Fee payment |
Year of fee payment: 3 |
|
PLFP | Fee payment |
Year of fee payment: 5 |
|
PLFP | Fee payment |
Year of fee payment: 6 |
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PLFP | Fee payment |
Year of fee payment: 7 |
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PLFP | Fee payment |
Year of fee payment: 8 |