DK1214088T3 - Proteiner udtrykt af Mycobacterium tuberculosis og ikke af BCG og anvendelse heraf som diagnostiske reagenser og vacciner - Google Patents

Proteiner udtrykt af Mycobacterium tuberculosis og ikke af BCG og anvendelse heraf som diagnostiske reagenser og vacciner

Info

Publication number
DK1214088T3
DK1214088T3 DK00928851T DK00928851T DK1214088T3 DK 1214088 T3 DK1214088 T3 DK 1214088T3 DK 00928851 T DK00928851 T DK 00928851T DK 00928851 T DK00928851 T DK 00928851T DK 1214088 T3 DK1214088 T3 DK 1214088T3
Authority
DK
Denmark
Prior art keywords
bcg
mycobacterium tuberculosis
vaccines
proteins expressed
diagnostic reagents
Prior art date
Application number
DK00928851T
Other languages
English (en)
Inventor
Maria L Gennaro
Original Assignee
Univ New Jersey Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22454351&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1214088(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ New Jersey Med filed Critical Univ New Jersey Med
Application granted granted Critical
Publication of DK1214088T3 publication Critical patent/DK1214088T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0006Skin tests, e.g. intradermal testing, test strips, delayed hypersensitivity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/04Mycobacterium, e.g. Mycobacterium tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/5695Mycobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/35Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/555Interferons [IFN]
    • G01N2333/57IFN-gamma
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/26Infectious diseases, e.g. generalised sepsis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/863Mycobacterium

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Physiology (AREA)
DK00928851T 1999-05-04 2000-05-04 Proteiner udtrykt af Mycobacterium tuberculosis og ikke af BCG og anvendelse heraf som diagnostiske reagenser og vacciner DK1214088T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13250599P 1999-05-04 1999-05-04
PCT/US2000/012257 WO2000066157A1 (en) 1999-05-04 2000-05-04 Proteins expressed by mycobacterium tuberculosis and not by bcg and their use as diagnostic reagents and vaccines

Publications (1)

Publication Number Publication Date
DK1214088T3 true DK1214088T3 (da) 2009-08-24

Family

ID=22454351

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00928851T DK1214088T3 (da) 1999-05-04 2000-05-04 Proteiner udtrykt af Mycobacterium tuberculosis og ikke af BCG og anvendelse heraf som diagnostiske reagenser og vacciner

Country Status (10)

Country Link
US (12) US7932373B1 (da)
EP (2) EP2087906A1 (da)
JP (1) JP4820489B2 (da)
AT (1) ATE429245T1 (da)
AU (1) AU773268B2 (da)
CA (1) CA2372583C (da)
DE (1) DE60042078D1 (da)
DK (1) DK1214088T3 (da)
ES (1) ES2326257T3 (da)
WO (1) WO2000066157A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2087906A1 (en) 1999-05-04 2009-08-12 The University of Medicine and Dentistry of New Jersey Proteins expressed by Mycobacterium tuberculosis and not by BCG and their use as diagnostic reagents and vaccines
CA2405247A1 (en) * 2000-04-19 2001-10-25 Statens Serum Institut Tuberculosis antigens and methods of use thereof
DE60236573D1 (de) * 2002-04-05 2010-07-15 Pasteur Institut Identifizierung der Virulenz-assoziierten Regionen RD1 und RD5, die die Entwicklung von verbesserten Impfstoffen mit M. bovis BCG und M. microti ermöglicht
AU2003224313A1 (en) * 2002-04-27 2003-11-17 The Secretary Of State For Environment, Food And Rural Affairs Mycobacterial antigens and uses thereof
GB0229444D0 (en) * 2002-12-18 2003-01-22 Royal Free Hampstead Nhs Trust Diagnostic method and assay kit
ES2534428T3 (es) 2005-07-26 2015-04-22 Rutgers, The State University Of New Jersey Perfiles de anticuerpos específicos de un estado tuberculoso
US8465753B2 (en) * 2007-04-23 2013-06-18 Robert J. Greenstein Combination vaccines against Mycobacterium sp. and methods of using the same
BRPI0708865A8 (pt) * 2006-03-14 2019-01-22 Univ Oregon Health & Science métodos para produzir uma resposta imune à tuberculose
GB0618127D0 (en) * 2006-09-14 2006-10-25 Isis Innovation Biomarker
CA2668100C (en) * 2006-11-01 2014-12-23 Immport Therapeutics, Inc. Compositions and methods for immunodominant antigens
ES2335177B1 (es) * 2008-09-19 2011-02-28 Archivel Farma, S.L. Agente inmunoterapeutico apropiado para la profilaxis primaria de la tuberculosis.
EP2812704A4 (en) 2012-02-07 2016-03-23 Intuitive Biosciences Inc KOCH BACILLUS SPECIFIC PEPTIDES FOR THE DETECTION OF INFECTION OR IMMUNIZATION IN NON-HUMAN PRIMATES
CN104628834B (zh) * 2015-01-23 2016-03-23 中国疾病预防控制中心传染病预防控制所 一种结核感染t细胞免疫检测抗原及其应用
EP3555630B1 (en) 2016-12-14 2023-05-31 Becton, Dickinson and Company Methods and compositions for obtaining a tuberculosis assessment in a subject

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977263A (en) 1992-12-10 1999-11-02 3M Innovative Properties Company Thermal transfer compositions, articles and graphic articles made with same
HU227778B1 (en) * 1995-09-01 2012-02-28 Corixa Corp Immogen peptid of m. tuberculosis origin, therapeutic and diagnostic use thereof
US6290969B1 (en) 1995-09-01 2001-09-18 Corixa Corporation Compounds and methods for immunotherapy and diagnosis of tuberculosis
PT2154248E (pt) * 1995-09-01 2012-01-16 Corixa Corp Compostos e métodos para diagnóstico de tuberculose
ES2152419T3 (es) 1995-09-08 2001-02-01 Textilma Ag Telar.
IL129389A0 (en) 1996-10-11 2000-02-17 Corixa Corp Compounds and methods for diagnsosis of tuberculosis
AU740545B2 (en) 1997-04-02 2001-11-08 Statens Serum Institut Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis
WO1999004005A1 (en) 1997-07-16 1999-01-28 Institut Pasteur A polynucleotide functionally coding for the lhp protein from mycobacterium tuberculosis, its biologically active derivative fragments, as well as methods using the same
US6291190B1 (en) 1998-08-25 2001-09-18 The Board Of Trustees Of The Leland Stanford Junior University Molecular differences between species of the M. tuberculosis complex
EP2087906A1 (en) 1999-05-04 2009-08-12 The University of Medicine and Dentistry of New Jersey Proteins expressed by Mycobacterium tuberculosis and not by BCG and their use as diagnostic reagents and vaccines
CA2405247A1 (en) 2000-04-19 2001-10-25 Statens Serum Institut Tuberculosis antigens and methods of use thereof
AU2003224313A1 (en) 2002-04-27 2003-11-17 The Secretary Of State For Environment, Food And Rural Affairs Mycobacterial antigens and uses thereof
US20070024122A1 (en) * 2005-07-27 2007-02-01 Steve Belson System and method for a distributed front end rectifier power system

Also Published As

Publication number Publication date
US20110052637A1 (en) 2011-03-03
EP1214088B1 (en) 2009-04-22
US20130149719A1 (en) 2013-06-13
US9844604B2 (en) 2017-12-19
JP2003519467A (ja) 2003-06-24
US20160169888A1 (en) 2016-06-16
CA2372583A1 (en) 2000-11-09
US20100016415A1 (en) 2010-01-21
US8021832B2 (en) 2011-09-20
US20130251739A1 (en) 2013-09-26
JP4820489B2 (ja) 2011-11-24
US9238066B2 (en) 2016-01-19
US8992942B2 (en) 2015-03-31
ATE429245T1 (de) 2009-05-15
US20160153986A1 (en) 2016-06-02
EP2087906A1 (en) 2009-08-12
US20070224123A1 (en) 2007-09-27
US9782495B2 (en) 2017-10-10
DE60042078D1 (de) 2009-06-04
CA2372583C (en) 2012-07-10
ES2326257T3 (es) 2009-10-06
EP1214088A4 (en) 2003-06-11
AU773268C (en) 2000-11-17
US8623609B2 (en) 2014-01-07
US20070224122A1 (en) 2007-09-27
US9482671B2 (en) 2016-11-01
AU4702300A (en) 2000-11-17
EP1214088A1 (en) 2002-06-19
WO2000066157A1 (en) 2000-11-09
US20170043038A1 (en) 2017-02-16
US20120107247A1 (en) 2012-05-03
AU773268B2 (en) 2004-05-20
US20140220600A1 (en) 2014-08-07
US7932373B1 (en) 2011-04-26
US7709211B2 (en) 2010-05-04
US8974800B2 (en) 2015-03-10
US7579141B2 (en) 2009-08-25

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