TR200806259T2 - Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler - Google Patents
Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşiklerInfo
- Publication number
- TR200806259T2 TR200806259T2 TR2008/06259T TR200806259T TR200806259T2 TR 200806259 T2 TR200806259 T2 TR 200806259T2 TR 2008/06259 T TR2008/06259 T TR 2008/06259T TR 200806259 T TR200806259 T TR 200806259T TR 200806259 T2 TR200806259 T2 TR 200806259T2
- Authority
- TR
- Turkey
- Prior art keywords
- tuberculosis
- compounds
- diagnosis
- methods
- immunotherapy
- Prior art date
Links
- 201000008827 tuberculosis Diseases 0.000 title abstract 5
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000009169 immunotherapy Methods 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 230000036039 immunity Effects 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Cell Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Tüberküloza karşı koruyucu bağışıklık, sağlayan bileşikler ve yöntemler açıklanmaktadır. Sağlanan bileşikler bir ya da daha fazla M. tuberculosis proteininin en az bir immünojenik kısmını içeren polipeptidleri ve böyle polipeptidleri kodlayan DNA moleküllerini ihtiva etmektedir. Böyle bileşikler M. tuberculosis enfeksiyonuna karşı bağışıklık sağlayan aşılar ve/veya farmasötik kompozisyonlar halinde formüle edilebilmekte ve tüberkülozun teşhisi için kullanılabilmektedir.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52343695A | 1995-09-01 | 1995-09-01 | |
US53363495A | 1995-09-22 | 1995-09-22 | |
US62087496A | 1996-03-22 | 1996-03-22 | |
US65968396A | 1996-06-05 | 1996-06-05 | |
US68057496A | 1996-07-12 | 1996-07-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200806259T2 true TR200806259T2 (tr) | 2008-10-21 |
Family
ID=27541835
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2004/03064T TR200403064T2 (tr) | 1995-09-01 | 1996-08-30 | Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler. |
TR1998/00411T TR199800411T1 (tr) | 1995-09-01 | 1996-08-30 | Tüberkülozun teshisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bilesikler. |
TR2008/06258T TR200806258T2 (tr) | 1995-09-01 | 1996-08-30 | Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler |
TR2009/01109T TR200901109T1 (tr) | 1995-09-01 | 1996-08-30 | Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler |
TR2008/06259T TR200806259T2 (tr) | 1995-09-01 | 1996-08-30 | Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2004/03064T TR200403064T2 (tr) | 1995-09-01 | 1996-08-30 | Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler. |
TR1998/00411T TR199800411T1 (tr) | 1995-09-01 | 1996-08-30 | Tüberkülozun teshisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bilesikler. |
TR2008/06258T TR200806258T2 (tr) | 1995-09-01 | 1996-08-30 | Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler |
TR2009/01109T TR200901109T1 (tr) | 1995-09-01 | 1996-08-30 | Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler |
Country Status (24)
Country | Link |
---|---|
EP (5) | EP1347055B1 (tr) |
JP (5) | JP4382160B2 (tr) |
KR (1) | KR100433750B1 (tr) |
CN (1) | CN1117149C (tr) |
AT (5) | ATE337399T1 (tr) |
AU (1) | AU727602B2 (tr) |
BR (2) | BR9612997B1 (tr) |
CA (3) | CA2684425A1 (tr) |
CY (2) | CY2570B1 (tr) |
CZ (3) | CZ300953B6 (tr) |
DE (4) | DE69636487T2 (tr) |
DK (4) | DK0851927T3 (tr) |
ES (4) | ES2210392T3 (tr) |
HK (1) | HK1059282A1 (tr) |
HU (2) | HU225979B1 (tr) |
IL (1) | IL123506A (tr) |
MX (1) | MX9801638A (tr) |
NO (4) | NO324372B1 (tr) |
NZ (1) | NZ319377A (tr) |
PL (1) | PL186774B1 (tr) |
PT (4) | PT1398379E (tr) |
SI (1) | SI0851927T1 (tr) |
TR (5) | TR200403064T2 (tr) |
WO (1) | WO1997009428A2 (tr) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6991797B2 (en) | 1993-07-02 | 2006-01-31 | Statens Serum Institut | M. tuberculosis antigens |
US6641814B1 (en) | 1997-04-02 | 2003-11-04 | Statens Serum Institut | Nucleic acids fragments and polypeptide fragments derived from M. tuberculosis |
US6592877B1 (en) | 1995-09-01 | 2003-07-15 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
US6290969B1 (en) * | 1995-09-01 | 2001-09-18 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
US6458366B1 (en) | 1995-09-01 | 2002-10-01 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
CZ126699A3 (cs) * | 1996-10-11 | 1999-09-15 | Corixa Corporation | Polypeptid obsahující antigenní část rozpustného antigenu M. tuberculosis nebo variantu uvedeného antigenu, molekula DNA kódující tento polypeptid, expresivní vektor, hostitelská buňka, způsoby diagnostiky infekce M. tuberculosis a diagnostické kity |
US6544522B1 (en) * | 1998-12-30 | 2003-04-08 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis antigens and their uses |
US6350456B1 (en) | 1997-03-13 | 2002-02-26 | Corixa Corporation | Compositions and methods for the prevention and treatment of M. tuberculosis infection |
US6627198B2 (en) | 1997-03-13 | 2003-09-30 | Corixa Corporation | Fusion proteins of Mycobacterium tuberculosis antigens and their uses |
EP0972045A1 (en) * | 1997-04-02 | 2000-01-19 | Statens Seruminstitut | NUCLEIC ACID FRAGMENTS AND POLYPEPTIDE FRAGMENTS DERIVED FROM $i(M. TUBERCULOSIS) |
US6982085B2 (en) | 1997-04-02 | 2006-01-03 | Statens Serum Institut | TB diagnostic based on antigens from M. tuberculosis |
US7037510B2 (en) | 1997-04-18 | 2006-05-02 | Statens Serum Institut | Hybrids of M. tuberculosis antigens |
US6555653B2 (en) * | 1997-05-20 | 2003-04-29 | Corixa Corporation | Compounds for diagnosis of tuberculosis and methods for their use |
US6613881B1 (en) * | 1997-05-20 | 2003-09-02 | Corixa Corporation | Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use |
CA2296419A1 (en) * | 1997-07-16 | 1999-01-28 | Institut Pasteur | A polynucleotide functionally coding for the lhp protein from mycobacterium tuberculosis, its biologically active derivative fragments, as well as methods using the same |
EP1484405A1 (en) * | 1997-11-10 | 2004-12-08 | Statens Serum Institut | Nucleic acid fragments and polypeptide fragments derived from M. Tuberculosis |
EP1029053A1 (en) * | 1997-11-10 | 2000-08-23 | Statens Seruminstitut | Nucleic acid fragments and polypeptide fragments derived from mycobacterium tuberculosis |
CN1629185B (zh) | 1998-04-07 | 2011-11-02 | 科里克萨公司 | 结核杆菌抗原融合蛋白及其应用 |
GB9808720D0 (en) * | 1998-04-23 | 1998-06-24 | Smithkline Beecham Biolog | Novel compounds |
DE69941545D1 (de) * | 1998-11-04 | 2009-11-26 | Isis Innovation | Tuberkulose diagnose test |
US6465633B1 (en) | 1998-12-24 | 2002-10-15 | Corixa Corporation | Compositions and methods of their use in the treatment, prevention and diagnosis of tuberculosis |
AU2594500A (en) * | 1998-12-24 | 2000-07-31 | Corixa Corporation | Methods for using mycobacterium tuberculosis molecules as immunological adjuvants |
DK1214088T3 (da) * | 1999-05-04 | 2009-08-24 | Univ New Jersey Med | Proteiner udtrykt af Mycobacterium tuberculosis og ikke af BCG og anvendelse heraf som diagnostiske reagenser og vacciner |
US7009042B1 (en) * | 1999-10-07 | 2006-03-07 | Corixa Corporation | Methods of using a Mycobacterium tuberculosis coding sequence to facilitate stable and high yield expression of the heterologous proteins |
US6316205B1 (en) | 2000-01-28 | 2001-11-13 | Genelabs Diagnostics Pte Ltd. | Assay devices and methods of analyte detection |
WO2001062893A2 (en) | 2000-02-25 | 2001-08-30 | Corixa Corporation | Compounds and methods for diagnosis and immunotherapy of tuberculosis |
ES2374620T3 (es) | 2000-06-20 | 2012-02-20 | Corixa Corporation | Antígeno mtb32a de mycobacterium tuberculosis con el sitio activo inactivado y proteínas de fusión de los mismos. |
AU2003213118A1 (en) | 2002-02-15 | 2003-09-09 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis |
ITRM20040091A1 (it) | 2004-02-19 | 2004-05-19 | Istituto Naz Per Le Malattie | Test immunologico rapido per la diagnosi ed il monitoraggio dell'infezione tubercolare. |
FI119445B (fi) * | 2004-10-29 | 2008-11-14 | Waertsilae Finland Oy | Polttomoottorin polttoaineen syöttöjärjestelmän paineen värähtelyn vaimennin |
NZ555907A (en) | 2004-11-16 | 2009-12-24 | Aeras Global Tb Vaccine Found | Multivalent vaccines comprising recombinant viral vectors |
EP1877426B1 (en) | 2005-04-29 | 2012-02-01 | GlaxoSmithKline Biologicals SA | Method for preventing or treating m tuberculosis infection |
FR2952058B1 (fr) * | 2009-10-29 | 2013-10-04 | Centre Nat Rech Scient | Procede de ligation native de polypeptides |
JP6010463B2 (ja) | 2010-01-27 | 2016-10-19 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 改変された結核抗原 |
EA027920B1 (ru) | 2010-12-14 | 2017-09-29 | Глаксосмитклайн Байолоджикалс С.А. | Композиция микобактериальных антигенов |
FR2971509B1 (fr) * | 2011-02-16 | 2013-02-22 | Centre Nat Rech Scient | Procede de preparation de peptides par assemblage de multiples fragments peptidiques |
CN103290030A (zh) * | 2012-02-23 | 2013-09-11 | 上海交通大学 | 一种结核分枝杆菌标志物HtdY的重组蛋白及其制备方法和临床应用 |
CN104284674A (zh) * | 2012-05-04 | 2015-01-14 | 辉瑞公司 | 前列腺相关抗原及基于疫苗的免疫治疗疗法 |
BR112016023040A2 (pt) * | 2014-04-04 | 2018-01-16 | Vestaron Corporation | processo para aumentar a atividade ou toxicidade de um peptídeo |
GB201513176D0 (en) | 2015-07-27 | 2015-09-09 | Glaxosmithkline Biolog Sa | Novel methods for inducing an immune response |
FR3048286B1 (fr) * | 2016-02-26 | 2021-01-22 | Omunis | Peptides immunogenes et leur utilisation |
CN107304231B (zh) * | 2016-04-18 | 2021-01-01 | 华中农业大学 | 一种结核分枝杆菌融合蛋白及应用 |
GB201614485D0 (en) * | 2016-08-25 | 2016-10-12 | Univ Oxford Innovation Ltd | Immunogenic composition |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2244539A1 (en) * | 1973-07-13 | 1975-04-18 | Mitsui Pharmaceuticals | Tuberculin active proteins and peptides prepn - from tubercle bacillus |
FR2265402A1 (en) * | 1974-03-29 | 1975-10-24 | Mitsui Pharmaceuticals | Tuberculin active proteins and peptides prepn - from tubercle bacillus |
US4876089A (en) * | 1984-09-06 | 1989-10-24 | Chiron Corporation | Feline leukemia virus protein vaccines |
US4751180A (en) | 1985-03-28 | 1988-06-14 | Chiron Corporation | Expression using fused genes providing for protein product |
US4935233A (en) | 1985-12-02 | 1990-06-19 | G. D. Searle And Company | Covalently linked polypeptide cell modulators |
US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
US4897268A (en) | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
FR2677365B1 (fr) * | 1991-06-07 | 1995-08-04 | Pasteur Institut | Proteines de mycobacterium et applications. |
US5330754A (en) * | 1992-06-29 | 1994-07-19 | Archana Kapoor | Membrane-associated immunogens of mycobacteria |
DK79893D0 (da) * | 1993-07-02 | 1993-07-02 | Statens Seruminstitut | New vaccine |
DK79793D0 (da) * | 1993-07-02 | 1993-07-02 | Statens Seruminstitut | Diagnostic test |
-
1996
- 1996-08-30 AT AT03021501T patent/ATE337399T1/de active
- 1996-08-30 EP EP03005931A patent/EP1347055B1/en not_active Expired - Lifetime
- 1996-08-30 PT PT03021501T patent/PT1398379E/pt unknown
- 1996-08-30 CA CA002684425A patent/CA2684425A1/en not_active Abandoned
- 1996-08-30 EP EP06112509A patent/EP1712628B1/en not_active Expired - Lifetime
- 1996-08-30 ES ES96933009T patent/ES2210392T3/es not_active Expired - Lifetime
- 1996-08-30 AU AU71586/96A patent/AU727602B2/en not_active Expired
- 1996-08-30 CN CN96197639A patent/CN1117149C/zh not_active Expired - Lifetime
- 1996-08-30 ES ES03021501T patent/ES2271449T3/es not_active Expired - Lifetime
- 1996-08-30 KR KR10-1998-0701589A patent/KR100433750B1/ko not_active IP Right Cessation
- 1996-08-30 WO PCT/US1996/014674 patent/WO1997009428A2/en active Application Filing
- 1996-08-30 EP EP01126628A patent/EP1203817B9/en not_active Expired - Lifetime
- 1996-08-30 BR BRPI9612997-2A patent/BR9612997B1/pt not_active IP Right Cessation
- 1996-08-30 TR TR2004/03064T patent/TR200403064T2/tr unknown
- 1996-08-30 HU HU9900902A patent/HU225979B1/hu not_active IP Right Cessation
- 1996-08-30 DK DK96933009T patent/DK0851927T3/da active
- 1996-08-30 PT PT01126628T patent/PT1203817E/pt unknown
- 1996-08-30 DK DK03021501T patent/DK1398379T3/da active
- 1996-08-30 AT AT01126628T patent/ATE323165T1/de active
- 1996-08-30 DK DK01126628T patent/DK1203817T3/da active
- 1996-08-30 CZ CZ20090166A patent/CZ300953B6/cs not_active IP Right Cessation
- 1996-08-30 DE DE69636487T patent/DE69636487T2/de not_active Expired - Lifetime
- 1996-08-30 PT PT96933009T patent/PT851927E/pt unknown
- 1996-08-30 HU HU0900047A patent/HU227778B1/hu unknown
- 1996-08-30 CA CA2653566A patent/CA2653566C/en not_active Expired - Lifetime
- 1996-08-30 DE DE69637879T patent/DE69637879D1/de not_active Expired - Lifetime
- 1996-08-30 MX MX9801638A patent/MX9801638A/es not_active IP Right Cessation
- 1996-08-30 EP EP96933009A patent/EP0851927B1/en not_active Expired - Lifetime
- 1996-08-30 ES ES03005931T patent/ES2324529T3/es not_active Expired - Lifetime
- 1996-08-30 CA CA002230885A patent/CA2230885C/en not_active Expired - Fee Related
- 1996-08-30 PL PL96325373A patent/PL186774B1/pl not_active IP Right Cessation
- 1996-08-30 TR TR1998/00411T patent/TR199800411T1/tr unknown
- 1996-08-30 DE DE69630457T patent/DE69630457T2/de not_active Expired - Lifetime
- 1996-08-30 TR TR2008/06258T patent/TR200806258T2/tr unknown
- 1996-08-30 TR TR2009/01109T patent/TR200901109T1/tr unknown
- 1996-08-30 CZ CZ20060387A patent/CZ300688B6/cs not_active IP Right Cessation
- 1996-08-30 CZ CZ0062898A patent/CZ297406B6/cs not_active IP Right Cessation
- 1996-08-30 AT AT06112509T patent/ATE513915T1/de not_active IP Right Cessation
- 1996-08-30 DK DK03005931T patent/DK1347055T3/da active
- 1996-08-30 AT AT96933009T patent/ATE252640T1/de not_active IP Right Cessation
- 1996-08-30 ES ES01126628T patent/ES2262595T3/es not_active Expired - Lifetime
- 1996-08-30 NZ NZ319377A patent/NZ319377A/xx not_active IP Right Cessation
- 1996-08-30 JP JP51146497A patent/JP4382160B2/ja not_active Expired - Lifetime
- 1996-08-30 BR BRPI9610262-4B1A patent/BR9610262B1/pt not_active IP Right Cessation
- 1996-08-30 IL IL12350696A patent/IL123506A/en not_active IP Right Cessation
- 1996-08-30 SI SI9630644T patent/SI0851927T1/xx unknown
- 1996-08-30 TR TR2008/06259T patent/TR200806259T2/tr unknown
- 1996-08-30 EP EP03021501A patent/EP1398379B1/en not_active Expired - Lifetime
- 1996-08-30 PT PT03005931T patent/PT1347055E/pt unknown
- 1996-08-30 DE DE69636046T patent/DE69636046T2/de not_active Expired - Lifetime
- 1996-08-30 AT AT03005931T patent/ATE426025T1/de active
-
1998
- 1998-02-27 NO NO19980883A patent/NO324372B1/no not_active IP Right Cessation
-
2004
- 2004-03-08 HK HK04101684.5A patent/HK1059282A1/xx not_active IP Right Cessation
-
2006
- 2006-02-10 JP JP2006034593A patent/JP4324597B2/ja not_active Expired - Lifetime
- 2006-02-10 JP JP2006034592A patent/JP4324596B2/ja not_active Expired - Fee Related
- 2006-12-19 CY CY0600033A patent/CY2570B1/xx unknown
-
2007
- 2007-02-01 NO NO20070621A patent/NO20070621L/no not_active Application Discontinuation
- 2007-02-01 NO NO20070619A patent/NO20070619L/no not_active Application Discontinuation
- 2007-02-01 NO NO20070618A patent/NO336288B1/no not_active IP Right Cessation
- 2007-03-23 JP JP2007077972A patent/JP4324618B2/ja not_active Expired - Fee Related
-
2009
- 2009-04-08 JP JP2009094008A patent/JP2009159982A/ja not_active Ceased
- 2009-06-05 CY CY0900006A patent/CY2612B2/xx unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TR200806259T2 (tr) | Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler | |
WO1998053075A3 (en) | Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use | |
WO1998016646A3 (en) | Compounds and methods for immunotherapy and diagnosis of tuberculosis | |
WO1999042076A3 (en) | Compounds and methods for immunotherapy and diagnosis of tuberculosis | |
CY1108864T1 (el) | Ενωσεις για ανοσοθεραπεια και διαγνωση φυματιωσης και μεθοδοι χρησεις τους | |
AR010517A1 (es) | Compuestos y metodos para la inmunoterapia y diagnostico de tuberculosis |