TR200806259T2 - Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler - Google Patents

Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler

Info

Publication number
TR200806259T2
TR200806259T2 TR2008/06259T TR200806259T TR200806259T2 TR 200806259 T2 TR200806259 T2 TR 200806259T2 TR 2008/06259 T TR2008/06259 T TR 2008/06259T TR 200806259 T TR200806259 T TR 200806259T TR 200806259 T2 TR200806259 T2 TR 200806259T2
Authority
TR
Turkey
Prior art keywords
tuberculosis
compounds
diagnosis
methods
immunotherapy
Prior art date
Application number
TR2008/06259T
Other languages
English (en)
Inventor
G Reed Steven
A. W. Skeiky Yasir
C Dillon Davin
Campos-Neto Antonio
Houghton Raymond
H. Vedvick Thomas
R. Twardzik Daniel
Original Assignee
Corixa Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27541835&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200806259(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Corixa Corporation filed Critical Corixa Corporation
Publication of TR200806259T2 publication Critical patent/TR200806259T2/tr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Tüberküloza karşı koruyucu bağışıklık, sağlayan bileşikler ve yöntemler açıklanmaktadır. Sağlanan bileşikler bir ya da daha fazla M. tuberculosis proteininin en az bir immünojenik kısmını içeren polipeptidleri ve böyle polipeptidleri kodlayan DNA moleküllerini ihtiva etmektedir. Böyle bileşikler M. tuberculosis enfeksiyonuna karşı bağışıklık sağlayan aşılar ve/veya farmasötik kompozisyonlar halinde formüle edilebilmekte ve tüberkülozun teşhisi için kullanılabilmektedir.
TR2008/06259T 1995-09-01 1996-08-30 Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler TR200806259T2 (tr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US52343695A 1995-09-01 1995-09-01
US53363495A 1995-09-22 1995-09-22
US62087496A 1996-03-22 1996-03-22
US65968396A 1996-06-05 1996-06-05
US68057496A 1996-07-12 1996-07-12

Publications (1)

Publication Number Publication Date
TR200806259T2 true TR200806259T2 (tr) 2008-10-21

Family

ID=27541835

Family Applications (5)

Application Number Title Priority Date Filing Date
TR2004/03064T TR200403064T2 (tr) 1995-09-01 1996-08-30 Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler.
TR1998/00411T TR199800411T1 (tr) 1995-09-01 1996-08-30 Tüberkülozun teshisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bilesikler.
TR2008/06258T TR200806258T2 (tr) 1995-09-01 1996-08-30 Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler
TR2009/01109T TR200901109T1 (tr) 1995-09-01 1996-08-30 Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler
TR2008/06259T TR200806259T2 (tr) 1995-09-01 1996-08-30 Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler

Family Applications Before (4)

Application Number Title Priority Date Filing Date
TR2004/03064T TR200403064T2 (tr) 1995-09-01 1996-08-30 Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler.
TR1998/00411T TR199800411T1 (tr) 1995-09-01 1996-08-30 Tüberkülozun teshisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bilesikler.
TR2008/06258T TR200806258T2 (tr) 1995-09-01 1996-08-30 Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler
TR2009/01109T TR200901109T1 (tr) 1995-09-01 1996-08-30 Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler

Country Status (24)

Country Link
EP (5) EP1347055B1 (tr)
JP (5) JP4382160B2 (tr)
KR (1) KR100433750B1 (tr)
CN (1) CN1117149C (tr)
AT (5) ATE337399T1 (tr)
AU (1) AU727602B2 (tr)
BR (2) BR9612997B1 (tr)
CA (3) CA2684425A1 (tr)
CY (2) CY2570B1 (tr)
CZ (3) CZ300953B6 (tr)
DE (4) DE69636487T2 (tr)
DK (4) DK0851927T3 (tr)
ES (4) ES2210392T3 (tr)
HK (1) HK1059282A1 (tr)
HU (2) HU225979B1 (tr)
IL (1) IL123506A (tr)
MX (1) MX9801638A (tr)
NO (4) NO324372B1 (tr)
NZ (1) NZ319377A (tr)
PL (1) PL186774B1 (tr)
PT (4) PT1398379E (tr)
SI (1) SI0851927T1 (tr)
TR (5) TR200403064T2 (tr)
WO (1) WO1997009428A2 (tr)

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US6458366B1 (en) 1995-09-01 2002-10-01 Corixa Corporation Compounds and methods for diagnosis of tuberculosis
CZ126699A3 (cs) * 1996-10-11 1999-09-15 Corixa Corporation Polypeptid obsahující antigenní část rozpustného antigenu M. tuberculosis nebo variantu uvedeného antigenu, molekula DNA kódující tento polypeptid, expresivní vektor, hostitelská buňka, způsoby diagnostiky infekce M. tuberculosis a diagnostické kity
US6544522B1 (en) * 1998-12-30 2003-04-08 Corixa Corporation Fusion proteins of mycobacterium tuberculosis antigens and their uses
US6350456B1 (en) 1997-03-13 2002-02-26 Corixa Corporation Compositions and methods for the prevention and treatment of M. tuberculosis infection
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DK1214088T3 (da) * 1999-05-04 2009-08-24 Univ New Jersey Med Proteiner udtrykt af Mycobacterium tuberculosis og ikke af BCG og anvendelse heraf som diagnostiske reagenser og vacciner
US7009042B1 (en) * 1999-10-07 2006-03-07 Corixa Corporation Methods of using a Mycobacterium tuberculosis coding sequence to facilitate stable and high yield expression of the heterologous proteins
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ES2374620T3 (es) 2000-06-20 2012-02-20 Corixa Corporation Antígeno mtb32a de mycobacterium tuberculosis con el sitio activo inactivado y proteínas de fusión de los mismos.
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FI119445B (fi) * 2004-10-29 2008-11-14 Waertsilae Finland Oy Polttomoottorin polttoaineen syöttöjärjestelmän paineen värähtelyn vaimennin
NZ555907A (en) 2004-11-16 2009-12-24 Aeras Global Tb Vaccine Found Multivalent vaccines comprising recombinant viral vectors
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FR2952058B1 (fr) * 2009-10-29 2013-10-04 Centre Nat Rech Scient Procede de ligation native de polypeptides
JP6010463B2 (ja) 2010-01-27 2016-10-19 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 改変された結核抗原
EA027920B1 (ru) 2010-12-14 2017-09-29 Глаксосмитклайн Байолоджикалс С.А. Композиция микобактериальных антигенов
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Also Published As

Publication number Publication date
EP1347055A3 (en) 2003-11-26
JP4324597B2 (ja) 2009-09-02
PT851927E (pt) 2004-03-31
WO1997009428A2 (en) 1997-03-13
ATE337399T1 (de) 2006-09-15
BR9612997B1 (pt) 2012-01-10
CZ62898A3 (cs) 1999-10-13
TR200403064T2 (tr) 2005-08-22
HK1059282A1 (en) 2004-06-25
JP4324596B2 (ja) 2009-09-02
CZ300688B6 (cs) 2009-07-15
IL123506A0 (en) 1998-10-30
DE69636046T2 (de) 2006-11-23
MX9801638A (es) 1998-05-31
BR9610262B1 (pt) 2013-11-26
KR19990044347A (ko) 1999-06-25
IL123506A (en) 2004-12-15
TR200901109T1 (tr) 2012-02-21
HU227778B1 (en) 2012-02-28
PT1203817E (pt) 2006-08-31
EP0851927B1 (en) 2003-10-22
EP1712628A3 (en) 2007-05-23
BR9610262A (pt) 1999-07-06
PT1347055E (pt) 2009-06-19
DE69630457D1 (de) 2003-11-27
CN1117149C (zh) 2003-08-06
ES2262595T3 (es) 2006-12-01
NO980883L (no) 1998-04-27
JP2001517069A (ja) 2001-10-02
DE69636046D1 (de) 2006-05-24
CZ297406B6 (cs) 2006-12-13
ATE426025T1 (de) 2009-04-15
DE69636487T2 (de) 2007-05-03
TR199800411T1 (tr) 1998-05-21
EP1398379A3 (en) 2004-07-14
NO20070619L (no) 1998-04-27
CY2612B2 (en) 2010-12-22
JP4382160B2 (ja) 2009-12-09
CA2684425A1 (en) 1997-03-13
TR200806258T2 (tr) 2008-10-21
CA2653566A1 (en) 1997-03-13
NO20070618L (no) 1998-04-27
NO20070621L (no) 1998-04-27
AU727602B2 (en) 2000-12-14
EP1398379B1 (en) 2006-08-23
ES2210392T3 (es) 2004-07-01
JP2007228972A (ja) 2007-09-13
PL186774B1 (pl) 2004-02-27
WO1997009428A3 (en) 1997-07-17
CZ300953B6 (cs) 2009-09-23
EP1712628B1 (en) 2011-06-22
JP4324618B2 (ja) 2009-09-02
EP1712628A2 (en) 2006-10-18
AU7158696A (en) 1997-03-27
HU225979B1 (en) 2008-02-28
CA2653566C (en) 2013-06-25
EP0851927A2 (en) 1998-07-08
EP1203817A3 (en) 2003-01-29
ATE513915T1 (de) 2011-07-15
DK1347055T3 (da) 2009-06-29
NZ319377A (en) 2000-01-28
KR100433750B1 (ko) 2004-09-01
SI0851927T1 (en) 2004-02-29
JP2009159982A (ja) 2009-07-23
NO336288B1 (no) 2015-07-13
PT1398379E (pt) 2007-01-31
DK1398379T3 (da) 2007-01-08
DK0851927T3 (da) 2004-01-26
EP1347055B1 (en) 2009-03-18
ATE252640T1 (de) 2003-11-15
PL325373A1 (en) 1998-07-20
ES2324529T3 (es) 2009-08-10
DK1203817T3 (da) 2006-08-14
JP2006149406A (ja) 2006-06-15
CA2230885C (en) 2010-02-02
HUP9900902A3 (en) 2001-03-28
EP1203817A2 (en) 2002-05-08
CN1200147A (zh) 1998-11-25
CA2230885A1 (en) 1997-03-13
EP1347055A2 (en) 2003-09-24
JP2006187292A (ja) 2006-07-20
ES2271449T3 (es) 2007-04-16
DE69630457T2 (de) 2004-11-25
EP1203817B1 (en) 2006-04-12
NO324372B1 (no) 2007-10-01
EP1398379A2 (en) 2004-03-17
HUP9900902A2 (hu) 1999-07-28
CY2570B1 (en) 2008-07-02
EP1203817B9 (en) 2006-08-16
DE69636487D1 (de) 2006-10-05
DE69637879D1 (de) 2009-04-30
NO980883D0 (no) 1998-02-27
ATE323165T1 (de) 2006-04-15

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