DE69621607D1 - VERBINDUNGEN MIT AGGREGATIONS-MODULIERENDEN WIRKUNG AUF DAS AMYLOiD PROTEIN - Google Patents

VERBINDUNGEN MIT AGGREGATIONS-MODULIERENDEN WIRKUNG AUF DAS AMYLOiD PROTEIN

Info

Publication number
DE69621607D1
DE69621607D1 DE69621607T DE69621607T DE69621607D1 DE 69621607 D1 DE69621607 D1 DE 69621607D1 DE 69621607 T DE69621607 T DE 69621607T DE 69621607 T DE69621607 T DE 69621607T DE 69621607 D1 DE69621607 D1 DE 69621607D1
Authority
DE
Germany
Prior art keywords
aggregation
natural
compounds
amyloid
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69621607T
Other languages
English (en)
Other versions
DE69621607T2 (de
Inventor
A Findeis
Howard Benjamin
B Garnick
L Gefter
Arvind Hundal
Laura Kasman
Gary Musso
R Signer
James Wakefield
J Reed
Susan Molineaux
William Kubasek
Joseph Chin
Jung-Ja Lee
Michael Kelley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Praecis Pharmaceuticals Inc
Original Assignee
Praecis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27410601&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69621607(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/404,831 external-priority patent/US5817626A/en
Priority claimed from US08/475,579 external-priority patent/US5854215A/en
Application filed by Praecis Pharmaceuticals Inc filed Critical Praecis Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69621607D1 publication Critical patent/DE69621607D1/de
Publication of DE69621607T2 publication Critical patent/DE69621607T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
DE69621607T 1995-03-14 1996-03-14 VERBINDUNGEN MIT AGGREGATIONS-MODULIERENDEN WIRKUNG AUF DAS AMYLOiD PROTEIN Expired - Lifetime DE69621607T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/404,831 US5817626A (en) 1995-03-14 1995-03-14 Modulators of beta-amyloid peptide aggregation
US08/475,579 US5854215A (en) 1995-03-14 1995-06-07 Modulators of β-amyloid peptide aggregation
US54899895A 1995-10-27 1995-10-27
PCT/US1996/003492 WO1996028471A1 (en) 1995-03-14 1996-03-14 Modulators of amyloid aggregation

Publications (2)

Publication Number Publication Date
DE69621607D1 true DE69621607D1 (de) 2002-07-11
DE69621607T2 DE69621607T2 (de) 2003-01-02

Family

ID=27410601

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69621607T Expired - Lifetime DE69621607T2 (de) 1995-03-14 1996-03-14 VERBINDUNGEN MIT AGGREGATIONS-MODULIERENDEN WIRKUNG AUF DAS AMYLOiD PROTEIN

Country Status (8)

Country Link
US (5) US6319498B1 (de)
EP (1) EP0815134B1 (de)
JP (1) JPH11514333A (de)
AT (1) ATE218583T1 (de)
CA (1) CA2214247C (de)
DE (1) DE69621607T2 (de)
ES (1) ES2175083T3 (de)
WO (1) WO1996028471A1 (de)

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* Cited by examiner, † Cited by third party
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WO1996028471A1 (en) 1996-09-19
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EP0815134A1 (de) 1998-01-07
JPH11514333A (ja) 1999-12-07
US5854204A (en) 1998-12-29
US20110009343A1 (en) 2011-01-13
CA2214247C (en) 2004-02-10
ES2175083T3 (es) 2002-11-16
US20040005307A1 (en) 2004-01-08
US20020098173A1 (en) 2002-07-25
US7658917B2 (en) 2010-02-09
EP0815134B1 (de) 2002-06-05
ATE218583T1 (de) 2002-06-15

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