DE69836582D1 - Kurze peptide die die aktivität serine/threonine kinasen modulieren - Google Patents
Kurze peptide die die aktivität serine/threonine kinasen modulierenInfo
- Publication number
- DE69836582D1 DE69836582D1 DE69836582T DE69836582T DE69836582D1 DE 69836582 D1 DE69836582 D1 DE 69836582D1 DE 69836582 T DE69836582 T DE 69836582T DE 69836582 T DE69836582 T DE 69836582T DE 69836582 D1 DE69836582 D1 DE 69836582D1
- Authority
- DE
- Germany
- Prior art keywords
- modulate
- threonine
- kinasen
- serine
- short peptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/861,338 US6174993B1 (en) | 1997-05-21 | 1997-05-21 | Short peptides which selectively modulate the activity of serine/threonine kinases |
PCT/US1998/010319 WO1998053050A2 (en) | 1997-05-21 | 1998-05-20 | Short peptides which selectively modulate the activity of serine/threonine kinases |
US861338 | 2001-05-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69836582D1 true DE69836582D1 (de) | 2007-01-18 |
DE69836582T2 DE69836582T2 (de) | 2007-09-20 |
Family
ID=25335533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69836582T Expired - Lifetime DE69836582T2 (de) | 1997-05-21 | 1998-05-20 | Kurze peptide die die aktivität serine/threonine kinasen modulieren |
Country Status (9)
Country | Link |
---|---|
US (1) | US6174993B1 (de) |
EP (1) | EP0983346B1 (de) |
JP (1) | JP2002500649A (de) |
CN (1) | CN1257538A (de) |
AT (1) | ATE347590T1 (de) |
AU (1) | AU734642B2 (de) |
CA (1) | CA2290721A1 (de) |
DE (1) | DE69836582T2 (de) |
WO (1) | WO1998053050A2 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7285416B2 (en) | 2000-01-24 | 2007-10-23 | Gendaq Limited | Regulated gene expression in plants |
US6723694B1 (en) * | 1997-05-21 | 2004-04-20 | The Children's Medical Center Corp. | Short peptides which selectively modulate intracellular signalling |
US7037891B2 (en) | 1997-05-21 | 2006-05-02 | Children's Medical Center Corporation | Methods of modulating G-protein-coupled receptor kinase-associated signal transduction |
US20020028772A1 (en) * | 1997-05-21 | 2002-03-07 | Children's Med. Corporation, | Modulators of activity of G-protein-coupled receptor kinases |
AU3208999A (en) * | 1998-03-26 | 1999-10-18 | Gene Logic, Inc. | Identification of a cdna associated with ischemia in human heart tissue |
JP2002525382A (ja) * | 1998-09-25 | 2002-08-13 | ザ チルドレンズ メディカル センター コーポレイション | プロテインキナーゼの活性を選択的に調節するショートペプチド |
AU1942301A (en) * | 1999-12-09 | 2001-06-18 | Children's Medical Center Corporation | Short peptides from the B4 and B5 regions of protein kinases which selectively modulate protein activity |
CN1331319A (zh) * | 2000-06-30 | 2002-01-16 | 上海博德基因开发有限公司 | 一种新的多肽——sr蛋白特异性丝氨酸激酶212.98和编码这种多肽的多核苷酸 |
US20040072184A1 (en) * | 2000-09-20 | 2004-04-15 | Thillainathan Yoganathan | Cancer associated protein kinases and their uses |
US20020115173A1 (en) * | 2000-12-11 | 2002-08-22 | Children's Medical Center Corporation | Short peptides from the 'A-region' of protein kinases which selectively modulate protein kinase activity |
CN1545422B (zh) * | 2001-01-17 | 2010-09-22 | 罗伯特·H·齐默尔 | 通过口服和胃肠道外给予含有肽原料药和其它不易吸收的活性成分的组合物来增强药物活性的组合物和方法 |
IL144583A0 (en) * | 2001-07-26 | 2002-05-23 | Peptor Ltd | Chimeric protein kinase inhibitors |
JP2003230388A (ja) * | 2001-12-05 | 2003-08-19 | Sumitomo Pharmaceut Co Ltd | 糖・脂質代謝異常疾患マーカーおよびその利用 |
FR2851460B1 (fr) * | 2003-02-21 | 2007-05-11 | Seppic Sa | Utilisation de n-lauroyl aminoacides comme actif cosmetique et pharmaceutique amincissant |
IL156429A0 (en) * | 2003-06-12 | 2004-01-04 | Peptor Ltd | Cell permeable conjugates of peptides for inhibition of protein kinases |
JP4819321B2 (ja) * | 2003-12-15 | 2011-11-24 | 独立行政法人科学技術振興機構 | Akt活性特異的抑制ポリペプチド |
AR056645A1 (es) | 2005-03-29 | 2007-10-17 | Icos Corp | Compuestos de urea sustituida inhibidores de enzimas chk1 . |
US8158586B2 (en) * | 2005-04-11 | 2012-04-17 | Pharmagap Inc. | Inhibitors of protein kinases and uses thereof |
EP1878804A4 (de) * | 2005-04-18 | 2009-09-23 | Hubit Genomix Inc | Gengrk5 in verbundung mit morbus perkinson und verwendung davon |
ATE540971T1 (de) | 2005-06-29 | 2012-01-15 | Hadasit Med Res Service | Proteinkinase-c-inhibitoren zur prävention von insulinresistenz und typ-2-diabetes |
JP5713614B2 (ja) * | 2010-09-14 | 2015-05-07 | スズキ株式会社 | 燃料電池システムおよび燃料電池車 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69323185T2 (de) | 1992-02-24 | 1999-07-08 | Smithkline Beecham Corp | Proteinkinase c-inhibitor |
US5935803A (en) | 1994-02-01 | 1999-08-10 | Terrapin Technologies, Inc. | Methods to identify immunomodulators using cognate interaction of PKC-theta |
-
1997
- 1997-05-21 US US08/861,338 patent/US6174993B1/en not_active Expired - Fee Related
-
1998
- 1998-05-20 EP EP98923571A patent/EP0983346B1/de not_active Expired - Lifetime
- 1998-05-20 CN CN98805328A patent/CN1257538A/zh active Pending
- 1998-05-20 CA CA002290721A patent/CA2290721A1/en not_active Abandoned
- 1998-05-20 AT AT98923571T patent/ATE347590T1/de not_active IP Right Cessation
- 1998-05-20 DE DE69836582T patent/DE69836582T2/de not_active Expired - Lifetime
- 1998-05-20 AU AU75833/98A patent/AU734642B2/en not_active Ceased
- 1998-05-20 WO PCT/US1998/010319 patent/WO1998053050A2/en active IP Right Grant
- 1998-05-20 JP JP55058098A patent/JP2002500649A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CN1257538A (zh) | 2000-06-21 |
EP0983346B1 (de) | 2006-12-06 |
WO1998053050A3 (en) | 1999-02-25 |
DE69836582T2 (de) | 2007-09-20 |
ATE347590T1 (de) | 2006-12-15 |
AU734642B2 (en) | 2001-06-21 |
US6174993B1 (en) | 2001-01-16 |
EP0983346A2 (de) | 2000-03-08 |
JP2002500649A (ja) | 2002-01-08 |
AU7583398A (en) | 1998-12-11 |
WO1998053050A2 (en) | 1998-11-26 |
CA2290721A1 (en) | 1998-11-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee | ||
8370 | Indication related to discontinuation of the patent is to be deleted |