DE69332577T2 - Verfahren zur Herstellung von 13-Ether-Derivaten von Milbemycinen und Zwischenprodukte - Google Patents

Verfahren zur Herstellung von 13-Ether-Derivaten von Milbemycinen und Zwischenprodukte

Info

Publication number
DE69332577T2
DE69332577T2 DE69332577T DE69332577T DE69332577T2 DE 69332577 T2 DE69332577 T2 DE 69332577T2 DE 69332577 T DE69332577 T DE 69332577T DE 69332577 T DE69332577 T DE 69332577T DE 69332577 T2 DE69332577 T2 DE 69332577T2
Authority
DE
Germany
Prior art keywords
intermediates
group
milbemycins
preparation
ether derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69332577T
Other languages
English (en)
Other versions
DE69332577D1 (de
Inventor
Mitsugi Shibano
Mutsuo Suzuki
Shunshi Kojima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Chemicals Agro Inc
Elanco Japan KK
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of DE69332577D1 publication Critical patent/DE69332577D1/de
Publication of DE69332577T2 publication Critical patent/DE69332577T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
DE69332577T 1992-09-01 1993-09-01 Verfahren zur Herstellung von 13-Ether-Derivaten von Milbemycinen und Zwischenprodukte Expired - Fee Related DE69332577T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP23344492 1992-09-01
JP26366092 1992-10-01
JP32284792 1992-12-02

Publications (2)

Publication Number Publication Date
DE69332577D1 DE69332577D1 (de) 2003-01-30
DE69332577T2 true DE69332577T2 (de) 2003-11-20

Family

ID=27331997

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69332577T Expired - Fee Related DE69332577T2 (de) 1992-09-01 1993-09-01 Verfahren zur Herstellung von 13-Ether-Derivaten von Milbemycinen und Zwischenprodukte

Country Status (14)

Country Link
US (2) US5461168A (de)
EP (1) EP0594291B1 (de)
JP (1) JP2654337B2 (de)
KR (1) KR0161541B1 (de)
AT (1) ATE229960T1 (de)
AU (1) AU666750B2 (de)
CA (1) CA2105251C (de)
DE (1) DE69332577T2 (de)
DK (1) DK0594291T3 (de)
ES (1) ES2186672T3 (de)
HK (1) HK1010371A1 (de)
NZ (1) NZ248559A (de)
PT (1) PT594291E (de)
TW (1) TW262474B (de)

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JP4499847B2 (ja) * 1998-05-25 2010-07-07 三井化学アグロ株式会社 ミルベマイシン類の１３−エステル誘導体の製造法
CN1111536C (zh) * 1998-05-25 2003-06-18 三共株式会社 密尔贝霉素类13－酯衍生物及其中间体的制备方法
JP2002121195A (ja) * 2000-10-12 2002-04-23 Sankyo Co Ltd １３位置換ミルベマイシン誘導体の製造法
US7687533B2 (en) 2004-03-18 2010-03-30 Pfizer Inc. N-(1-arylpyrazol-4l) sulfonamides and their use as parasiticides
US7919522B2 (en) 2007-05-03 2011-04-05 Merial Limited Compositions comprising C-13 alkoxyether macrolide compounds and phenylpyrazole compounds
TWI487486B (zh) 2009-12-01 2015-06-11 Syngenta Participations Ag 以異唑啉衍生物為主之殺蟲化合物
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JP2013520403A (ja) 2010-02-22 2013-06-06 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト 殺虫化合物としてのジヒドロフラン誘導体
JP2013520456A (ja) 2010-02-25 2013-06-06 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト イソオキサゾリン誘導体の製造方法
EP2625165B1 (de) 2010-10-05 2018-07-04 Syngenta Participations AG Insektizide pyrrolidin-yl-aryl-carboxamide
WO2012049327A2 (en) 2010-10-15 2012-04-19 Syngenta Participations Ag Pesticidal mixtures
EP2643302A1 (de) 2010-11-23 2013-10-02 Syngenta Participations AG Insektizidverbindungen
EP2651921A1 (de) 2010-12-17 2013-10-23 Syngenta Participations AG Insektizidverbindungen
CN103354811A (zh) 2011-02-09 2013-10-16 先正达参股股份有限公司 杀虫化合物
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JP6030640B2 (ja) 2011-05-18 2016-11-24 シンジェンタ パーティシペーションズ アーゲー アリールチオアセトアミド誘導体をベースとする殺虫化合物
US9339505B2 (en) 2011-05-31 2016-05-17 Syngenta Participations Ag Pesticidal mixtures including isoxazoline derivatives
AR086587A1 (es) 2011-05-31 2014-01-08 Syngenta Participations Ag Compuestos insecticidas
WO2012175474A1 (en) 2011-06-20 2012-12-27 Syngenta Participations Ag 1,2,3 triazole pesticides
CN103732567A (zh) 2011-08-22 2014-04-16 先正达参股股份有限公司 作为杀虫化合物的二氢呋喃衍生物
US20140343049A1 (en) 2011-08-22 2014-11-20 Syngenta Participations Ag Dihydrofuran derivatives as insecticidal compounds
US9307766B2 (en) 2011-08-25 2016-04-12 Syngenta Participations Ag Isoxazoline derivatives as insecticidal compounds
WO2013026929A1 (en) 2011-08-25 2013-02-28 Syngenta Participations Ag Dihydropyrrole derivatives as insecticidal compounds
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BR112014003730A2 (pt) 2011-08-25 2017-03-14 Syngenta Participations Ag processo para a preparação de derivados de tietano
WO2013026695A1 (en) 2011-08-25 2013-02-28 Syngenta Participations Ag Isoxazoline derivatives as insecticidal compounds
WO2013037626A1 (en) 2011-09-13 2013-03-21 Syngenta Participations Ag Isothiazoline derivatives as insecticidal compounds
AU2012320779B8 (en) 2011-10-03 2015-10-29 Syngenta Participations Ag Insecticidal 2-methoxybenzamide derivatives
JP2014534182A (ja) 2011-10-03 2014-12-18 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト 殺虫化合物としてのイソオキサゾリン誘導体
WO2013135674A1 (en) 2012-03-12 2013-09-19 Syngenta Participations Ag Insecticidal 2-aryl-acetamide compounds
WO2014001121A1 (en) 2012-06-25 2014-01-03 Syngenta Participations Ag Isothiazole derivatives as insecticidal compounds
WO2014001120A1 (en) 2012-06-25 2014-01-03 Syngenta Participations Ag Isothiazole derivatives as insecticidal compounds
BR112015009475A2 (pt) 2012-10-31 2017-07-04 Syngenta Participations Ag compostos inseticidas
WO2014079935A1 (en) 2012-11-21 2014-05-30 Syngenta Participations Ag Insecticidal compounds based on arylthioacetamide derivatives
US9402395B2 (en) 2013-04-02 2016-08-02 Syngenta Participations Ag Insecticidal compounds
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WO2015007451A1 (en) 2013-07-15 2015-01-22 Syngenta Participations Ag Microbiocidal heterobicyclic derivatives
EP3556744B1 (de) 2013-12-23 2022-06-01 Syngenta Participations AG Insektizide verbindungen
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WO2016087593A1 (en) 2014-12-05 2016-06-09 Syngenta Participations Ag Novel fungicidal quinolinylamidines
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US5625078A (en) 1997-04-29
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AU4497993A (en) 1994-03-10
ATE229960T1 (de) 2003-01-15
EP0594291A1 (de) 1994-04-27
EP0594291B1 (de) 2002-12-18
KR940007038A (ko) 1994-04-26
TW262474B (de) 1995-11-11
HK1010371A1 (en) 1999-06-17
DE69332577D1 (de) 2003-01-30
CA2105251A1 (en) 1994-03-02
AU666750B2 (en) 1996-02-22
NZ248559A (en) 1995-05-26
JP2654337B2 (ja) 1997-09-17
US5461168A (en) 1995-10-24
KR0161541B1 (ko) 1998-12-01
CA2105251C (en) 2004-12-07
PT594291E (pt) 2003-03-31

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