HUP0000298A2 - Eljárás aril-béta-diketon-, aril-pirimidin-keton-származékok és növényvédőszerek közbenső termékeinek előállítására - Google Patents

Eljárás aril-béta-diketon-, aril-pirimidin-keton-származékok és növényvédőszerek közbenső termékeinek előállítására

Info

Publication number
HUP0000298A2
HUP0000298A2 HU0000298A HUP0000298A HUP0000298A2 HU P0000298 A2 HUP0000298 A2 HU P0000298A2 HU 0000298 A HU0000298 A HU 0000298A HU P0000298 A HUP0000298 A HU P0000298A HU P0000298 A2 HUP0000298 A2 HU P0000298A2
Authority
HU
Hungary
Prior art keywords
alkyl
atom
general formula
aryl
hydrogen atom
Prior art date
Application number
HU0000298A
Other languages
English (en)
Inventor
Hsiao-Ling Mao Chin
Raymond Anthony Felix
David Louis Lee
Frank Xavier Woolard
Original Assignee
Zeneca Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Limited filed Critical Zeneca Limited
Publication of HUP0000298A2 publication Critical patent/HUP0000298A2/hu
Publication of HUP0000298A3 publication Critical patent/HUP0000298A3/hu

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/807—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen all halogen atoms bound to the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Abstract

A találmány tárgyát eljárás képezi a (II) általánős képletű aril-b-diketőn-származékők, és a (IV) általánős képletű aril-pirimidin-ketőn-származékők előállítására. A találmány tárgyát képezik magűk a (II),(IV) általánős képletű vegyületek, valamint a kiindűlási anyagkéntalkalmazőtt (III) és (V) általánős képletű vegyületek is. A találmányszerinti (II), (III), (IV) és (V) általánős képletű vegyületekeredményesen alkalmazhatók növényvédő szerek előállításáhőz közbensőtermékként. A (II) általánős képletben R1 jelentése hidrőgénatőm, 1-6 szénatőmős alkil-, 1-6 szénatőmőshalőgén-alkil-csőpőrt, halőgénatőm, nitrő- vagy 2-4 szénatőmősalkenilcsőpőrt; R2 jelentése 1-6 szénatőmős alkil-, 3-6 szénatőmős ciklőalkil- vagy 1-6 szénatőmős alkőxicsőpőrt; X1 jelentése hidrőgénatőm, halőgénatőm, 1-6 szénatőmős alkil- vagy 1-6szénatőmős halőgén-alkil-csőpőrt; és Z jelentése CH vagy N. A (III) általánős képletben R1 jelentése hidrőgénatőm, 1-6 szénatőmős alkil-, 1-6 szénatőmőshalőgén-alkil-csőpőrt, halőgénatőm, nitrő- vagy 2-4 szénatőmősalkenilcsőpőrt; R2 jelentése 1-6 szénatőmős alkil-, 3-6 szénatőmős ciklőalkil- vagy 1-6 szénatőmős alkőxicsőpőrt; X1 jelentése hidrőgénatőm, halőgénatőm, 1-6 szénatőmős alkil- vagy 1-6szénatőmős halőgén-alkil-csőpőrt; R3 jelentése alkil- vagy szűbsztitűált allilcsőpőrt; Z jelentése CH vagy N. A (IV) általánős képletben R1 jelentése hidrőgénatőm, 1-6 szénatőmős alkil-, 1-6 szénatőmőshalőgén-alkil-csőpőrt, halőgénatőm, nitrő- vagy 2-4 szénatőmősalkenilcsőpőrt; R4 jelentése 3-6 szénatőmős ciklőalkil- vagy hidrőxilcsőpőrt; X1 jelentése hidrőgénatőm, halőgénatőm, 1-6 szénatőmős alkil-vagy 1-6 szénatőmős halőgén-alkil-csőpőrt; és Z jelentése CH vagy N. Az (V) általánős képletben R1 jelentése hidrőgénatőm, 1-6 szénatőmős alkil-, 1-6 szénatőmőshalőgén-alkil-csőpőrt, halőgénatőm, nitrő- vagy 2-4 szénatőmősalkenilcsőpőrt; R2 jelentése 3-6 szénatőmős ciklőalkil- vagy 1-6 szénatőmősalkőxicsőpőrt; X1 jelentése hidrőgénatőm, halőgénatőm, 1-6 szénatőmős alkil- vagy 1-6szénatőmős halőgén-alkil-csőpőrt; és Z jelentése CH vagy N. (I) (II) (III) (IV) (V) ŕ
HU0000298A 1996-09-16 1997-09-12 Processes for the preparation of aryl-betha-diketones, aryl-pyrimidine ketones and crop protection intermediates HUP0000298A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/715,292 US5925795A (en) 1996-09-16 1996-09-16 Processes for the preparation of aryl-β-diketones, arylpyrimidine ketones and crop protection intermediates
PCT/GB1997/002515 WO1998011046A2 (en) 1996-09-16 1997-09-12 PROCESSES FOR THE PREPARATION OF ARYL-β-DIKETONES, ARYL-PYRIMIDINE KETONES AND CROP PROTECTION INTERMEDIATES

Publications (2)

Publication Number Publication Date
HUP0000298A2 true HUP0000298A2 (hu) 2000-06-28
HUP0000298A3 HUP0000298A3 (en) 2002-01-28

Family

ID=24873446

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0000298A HUP0000298A3 (en) 1996-09-16 1997-09-12 Processes for the preparation of aryl-betha-diketones, aryl-pyrimidine ketones and crop protection intermediates

Country Status (13)

Country Link
US (1) US5925795A (hu)
EP (1) EP0929510A2 (hu)
JP (1) JP2001501185A (hu)
KR (1) KR20000036145A (hu)
CN (1) CN1230943A (hu)
AU (1) AU734624B2 (hu)
BR (1) BR9711486A (hu)
CA (1) CA2265669A1 (hu)
EA (1) EA002129B1 (hu)
HU (1) HUP0000298A3 (hu)
IL (1) IL128802A0 (hu)
TR (1) TR199900593T2 (hu)
WO (1) WO1998011046A2 (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2335658A (en) * 1998-03-25 1999-09-29 Rhone Poulenc Agriculture Processes for preparing 1-aryl-3-cyclopropyl-propane-1,3-dione intermediates
RU2582236C1 (ru) * 2015-03-06 2016-04-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Пермский государственный национальный исследовательский университет" 4,4,4-трихлор-1-(4-хлорфенил)бутан-1,3-дион, обладающий анальгетической и противомикробной активностями

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3365448A (en) * 1964-08-11 1968-01-23 Sterling Drug Inc Acrylate derivatives
US3997530A (en) * 1974-07-24 1976-12-14 American Cyanamid Company Substituted enaminoketones
GB8310407D0 (en) * 1982-05-12 1983-05-25 Ici Plc 1 3 - dioxan -5- ylalkenoic acids
HU196884B (en) * 1985-10-01 1989-02-28 Mta Koezponti Kemiai Kutato In Herbicides comprising phenoxy-benzoyl-malon ester derivatives as active ingredient and process for producing the active ingredients
GB8920519D0 (en) * 1989-09-11 1989-10-25 Rhone Poulenc Ltd New compositions of matter
US5532416A (en) * 1994-07-20 1996-07-02 Monsanto Company Benzoyl derivatives and synthesis thereof
AU676689B2 (en) * 1992-11-06 1997-03-20 Rhone-Poulenc Chimie Beta-diketones, processes for making beta-diketones and use of beta-diketones as stabilizers for PVC
US5595958A (en) * 1994-05-02 1997-01-21 Zeneca Limited 3-substituted pyridine compounds and derivatives thereof
EP0758323A1 (en) * 1994-05-02 1997-02-19 Zeneca Limited Herbicidal hydroxybenzyl-substituted heteroaryl compounds and derivatives thereof
ES2129839T3 (es) * 1994-07-20 1999-06-16 Monsanto Co Derivados de benzoilo y su sintesis.

Also Published As

Publication number Publication date
BR9711486A (pt) 1999-08-24
WO1998011046A3 (en) 1998-05-14
AU734624B2 (en) 2001-06-21
TR199900593T2 (xx) 1999-05-21
CA2265669A1 (en) 1998-03-19
AU4216697A (en) 1998-04-02
EA199900296A1 (ru) 1999-08-26
US5925795A (en) 1999-07-20
KR20000036145A (ko) 2000-06-26
HUP0000298A3 (en) 2002-01-28
WO1998011046A2 (en) 1998-03-19
EA002129B1 (ru) 2001-12-24
EP0929510A2 (en) 1999-07-21
IL128802A0 (en) 2000-01-31
JP2001501185A (ja) 2001-01-30
CN1230943A (zh) 1999-10-06

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