LV10422A - Jaunie fluor-naftacendioni to glikozetie atvasinajumi un vinu razosanas panemiens - Google Patents

Jaunie fluor-naftacendioni to glikozetie atvasinajumi un vinu razosanas panemiens

Info

Publication number
LV10422A
LV10422A LV930656A LV930656A LV10422A LV 10422 A LV10422 A LV 10422A LV 930656 A LV930656 A LV 930656A LV 930656 A LV930656 A LV 930656A LV 10422 A LV10422 A LV 10422A
Authority
LV
Latvia
Prior art keywords
new
fluoronaphthendiones
alpha
hydrogen atom
glucose derivatives
Prior art date
Application number
LV930656A
Other languages
English (en)
Inventor
Alessandro Giolitti
Antonio Guidi
Franco Pasqui
Vittorio Pestellini
Federico Arcamone
Original Assignee
Menarini Farma Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT00956489A external-priority patent/IT1236322B/it
Priority claimed from IT9321A external-priority patent/IT1239017B/it
Priority claimed from IT9357A external-priority patent/IT1238673B/it
Application filed by Menarini Farma Ind filed Critical Menarini Farma Ind
Publication of LV10422A publication Critical patent/LV10422A/lv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B35/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving a change in the type of bonding between two carbon atoms already directly linked
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
    • C07D303/10—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals in which the oxirane rings are condensed with a carbocyclic ring system having three or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
LV930656A 1989-11-13 1993-06-22 Jaunie fluor-naftacendioni to glikozetie atvasinajumi un vinu razosanas panemiens LV10422A (lv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT00956489A IT1236322B (it) 1989-11-13 1989-11-13 8-fluoro-antracicline, relativi procedimenti di fabbricazione e loro uso.
IT9321A IT1239017B (it) 1990-02-20 1990-02-20 10-fluoro-antracicline, relativi procedimenti di fabbricazione e loro uso.
IT9357A IT1238673B (it) 1990-03-30 1990-03-30 8-fluoro-4-metossi-antracicline, relativi procedimenti di fabbricazione e loro uso.

Publications (1)

Publication Number Publication Date
LV10422A true LV10422A (lv) 1995-02-20

Family

ID=27272726

Family Applications (1)

Application Number Title Priority Date Filing Date
LV930656A LV10422A (lv) 1989-11-13 1993-06-22 Jaunie fluor-naftacendioni to glikozetie atvasinajumi un vinu razosanas panemiens

Country Status (24)

Country Link
EP (1) EP0436474B1 (lv)
JP (1) JPH03209343A (lv)
KR (1) KR940002983B1 (lv)
CN (1) CN1025608C (lv)
AT (1) ATE108760T1 (lv)
AU (1) AU641702B2 (lv)
BR (1) BR9005743A (lv)
CA (1) CA2029715A1 (lv)
CU (1) CU22303A3 (lv)
DE (1) DE69010874T2 (lv)
DK (1) DK0436474T3 (lv)
ES (1) ES2056433T3 (lv)
HU (1) HU208544B (lv)
IE (1) IE904002A1 (lv)
IL (1) IL96302A0 (lv)
LV (1) LV10422A (lv)
MA (1) MA21995A1 (lv)
NO (1) NO175101C (lv)
NZ (1) NZ236032A (lv)
PL (1) PL164019B1 (lv)
PT (1) PT95844B (lv)
RU (1) RU2015958C1 (lv)
TN (1) TNSN90131A1 (lv)
YU (1) YU47695B (lv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3943029A1 (de) * 1989-12-27 1991-07-04 Behringwerke Ag Verfahren zur herstellung von glycosyl-anthracyclinonen
CA2121929A1 (en) * 1994-04-22 1995-10-23 Pierre Doucet Gear reducer
IT1271689B (it) * 1994-08-04 1997-06-04 Menarini Farma Ind 8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono
AU3923995A (en) * 1994-11-22 1996-06-17 Novo Nordisk A/S Active bio-compounds
WO1999058543A1 (en) * 1998-05-13 1999-11-18 Instytut Farmaceutyczny New n-alkyloxycarbonyl derivatives of monosaccharides l-acosamine and l-daunosamine
WO2003035660A1 (fr) * 2001-10-23 2003-05-01 Sumitomo Chemical Company, Limited Stabilisation d'hydrochlorure d'amrubicine
US7053191B2 (en) 2003-05-21 2006-05-30 Solux Corporation Method of preparing 4-R-substituted 4-demethoxydaunorubicin
US8357785B2 (en) 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
US8846882B2 (en) 2011-04-29 2014-09-30 Synbias Pharma Ag Method of producing 4-demethoxydaunorubicin
RU2766222C2 (ru) * 2017-12-26 2022-02-10 Общество с ограниченной ответственностью "НИАРМЕДИК ФАРМА" Несимметричные производные полифенолов динафталинового ряда, способ их получения и применение
CN114230538B (zh) * 2021-12-21 2023-11-17 蚌埠医学院 一种环系蒽醌类化合物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8321676D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia 4'-haloanthrocycline glycosides
US4697005A (en) * 1985-03-20 1987-09-29 Ohio State University Research Foundation 1-fluoro, 4-fluoro, and 1,4-difluoro anthracycline anticancer antibiotics

Also Published As

Publication number Publication date
IE904002A1 (en) 1991-05-22
KR910009613A (ko) 1991-06-28
HUT55337A (en) 1991-05-28
EP0436474A1 (en) 1991-07-10
CN1052659A (zh) 1991-07-03
PL164019B1 (pl) 1994-06-30
YU47695B (sh) 1996-01-08
PT95844B (pt) 1997-11-28
JPH03209343A (ja) 1991-09-12
DE69010874T2 (de) 1994-11-10
MA21995A1 (fr) 1991-07-01
PT95844A (pt) 1991-09-13
CA2029715A1 (en) 1991-05-14
BR9005743A (pt) 1991-09-24
NO904907L (no) 1991-05-14
NZ236032A (en) 1993-09-27
DK0436474T3 (da) 1994-08-29
NO175101B (no) 1994-05-24
RU2015958C1 (ru) 1994-07-15
KR940002983B1 (ko) 1994-04-09
CN1025608C (zh) 1994-08-10
ES2056433T3 (es) 1994-10-01
ATE108760T1 (de) 1994-08-15
DE69010874D1 (de) 1994-08-25
AU6596090A (en) 1991-07-11
TNSN90131A1 (fr) 1991-03-05
YU212390A (sh) 1992-12-21
CU22303A3 (es) 1995-01-31
NO904907D0 (no) 1990-11-12
NO175101C (no) 1994-08-31
HU208544B (en) 1993-11-29
IL96302A0 (en) 1991-08-16
EP0436474B1 (en) 1994-07-20
PL287728A1 (en) 1992-11-02
AU641702B2 (en) 1993-09-30

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