DE60303305D1 - Verfahren zur verbesserung der reinheit und ausbeute von sucralose - Google Patents

Verfahren zur verbesserung der reinheit und ausbeute von sucralose

Info

Publication number
DE60303305D1
DE60303305D1 DE60303305T DE60303305T DE60303305D1 DE 60303305 D1 DE60303305 D1 DE 60303305D1 DE 60303305 T DE60303305 T DE 60303305T DE 60303305 T DE60303305 T DE 60303305T DE 60303305 D1 DE60303305 D1 DE 60303305D1
Authority
DE
Germany
Prior art keywords
sucralose
exploiting
improving purity
purity
improving
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60303305T
Other languages
English (en)
Other versions
DE60303305T2 (de
Inventor
J Catani
Edwin Wiley
M Vernon
Carolyn Merkel
Edward Micinski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tate and Lyle Technology Ltd
Original Assignee
Tate and Lyle PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tate and Lyle PLC filed Critical Tate and Lyle PLC
Publication of DE60303305D1 publication Critical patent/DE60303305D1/de
Application granted granted Critical
Publication of DE60303305T2 publication Critical patent/DE60303305T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Seasonings (AREA)
  • Saccharide Compounds (AREA)
  • Soy Sauces And Products Related Thereto (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60303305T 2002-03-08 2003-03-06 Verfahren zur verbesserung der reinheit und ausbeute von sucralose Expired - Fee Related DE60303305T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92730 2002-03-08
US10/092,730 US6998480B2 (en) 2002-03-08 2002-03-08 Process for improving sucralose purity and yield
PCT/US2003/006628 WO2003076454A1 (en) 2002-03-08 2003-03-06 Process for improving sucralose purity and yield

Publications (2)

Publication Number Publication Date
DE60303305D1 true DE60303305D1 (de) 2006-04-06
DE60303305T2 DE60303305T2 (de) 2006-09-21

Family

ID=27804179

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60303305T Expired - Fee Related DE60303305T2 (de) 2002-03-08 2003-03-06 Verfahren zur verbesserung der reinheit und ausbeute von sucralose
DE60316853T Expired - Fee Related DE60316853T2 (de) 2002-03-08 2003-03-06 Verfahren zur Gewinnung von Sucralose mit hoher Reinheit und hoher Ausbeute

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60316853T Expired - Fee Related DE60316853T2 (de) 2002-03-08 2003-03-06 Verfahren zur Gewinnung von Sucralose mit hoher Reinheit und hoher Ausbeute

Country Status (19)

Country Link
US (1) US6998480B2 (de)
EP (2) EP1657246B1 (de)
JP (1) JP4916089B2 (de)
KR (1) KR101025235B1 (de)
CN (1) CN1330659C (de)
AR (1) AR038902A1 (de)
AT (2) ATE375357T1 (de)
AU (6) AU2003216516B2 (de)
BR (1) BR0308292A (de)
CA (1) CA2481402A1 (de)
DE (2) DE60303305T2 (de)
DK (2) DK1657246T3 (de)
ES (2) ES2296057T3 (de)
IL (2) IL163717A0 (de)
MX (1) MXPA04009925A (de)
PT (2) PT1657246E (de)
RU (1) RU2324407C2 (de)
TW (1) TW200400196A (de)
WO (1) WO2003076454A1 (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060088638A1 (en) * 2002-07-29 2006-04-27 Merkel Carolyn M Method of improving sweetness delivery of sucralose
US6943248B2 (en) * 2003-04-30 2005-09-13 Tate & Lyle Public Limited Company Crystalline form of sucralose, and method for producing it
CA2558683A1 (en) * 2004-03-05 2005-09-22 Sunil Srivastava High-intensity sweetener-polyol compositions
US20060188629A1 (en) * 2005-01-21 2006-08-24 Greg Liesen Method for the purification of sucralose
US20100190975A1 (en) * 2005-06-01 2010-07-29 Pharmed Medicare Private Limited Method for purification of chlorinated sucrose derivatives by solvent extraction
CN101253187A (zh) * 2005-08-30 2008-08-27 法马德医疗保险私人有限公司 含有蔗糖酯的反应物中吡啶及其类似物的除去方法
JP2009509925A (ja) * 2005-08-30 2009-03-12 ファームド メディケア プライヴェート リミテッド 疎水性親和性クロマトグラフィに基づく塩素化スクロースの生成方法
US8956677B2 (en) * 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with glucosamine and compositions sweetened therewith
US20070116822A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-potency sweetener composition with saponin and compositions sweetened therewith
US20070116825A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Confection with High-Potency Sweetener
EP1965667A2 (de) * 2005-11-23 2008-09-10 The Coca-Cola Company Synthetische süssmittelzusammensetzungen mit verbessertem zeitverlaufsprofil und/oder geschmacksprofil, verfahren zu ihrer formulierung und ihre verwendungen
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US9144251B2 (en) * 2005-11-23 2015-09-29 The Coca-Cola Company High-potency sweetener composition with mineral and compositions sweetened therewith
US8956678B2 (en) * 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with preservative and compositions sweetened therewith
US20070116836A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Osteoporosis and Compositions Sweetened Therewith
US8993027B2 (en) * 2005-11-23 2015-03-31 The Coca-Cola Company Natural high-potency tabletop sweetener compositions with improved temporal and/or flavor profile, methods for their formulation, and uses
US20070134391A1 (en) * 2005-11-23 2007-06-14 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Autoimmune Disorders and Compositions Sweetened Therewith
US20070116831A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Dental Composition with High-Potency Sweetener
US7741477B2 (en) * 2006-01-10 2010-06-22 Alembic Limited Process for purification of sucralose
CN100372859C (zh) * 2006-03-17 2008-03-05 广西大学 医药级蔗糖的制备方法
US9012626B2 (en) * 2006-06-19 2015-04-21 The Coca-Cola Company Rebaudioside a composition and method for purifying rebaudioside a
US8791253B2 (en) * 2006-06-19 2014-07-29 The Coca-Cola Company Rebaudioside A composition and method for purifying rebaudioside A
US20090312538A1 (en) * 2006-07-06 2009-12-17 Alembic Limited process for the preparation of sucralose of high purity
US20080103295A1 (en) * 2006-10-25 2008-05-01 David Losan Ho Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst
US8258291B2 (en) * 2006-10-25 2012-09-04 Mamtek International Limited Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC)
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
US9101161B2 (en) * 2006-11-02 2015-08-11 The Coca-Cola Company High-potency sweetener composition with phytoestrogen and compositions sweetened therewith
US20080107787A1 (en) * 2006-11-02 2008-05-08 The Coca-Cola Company Anti-Diabetic Composition with High-Potency Sweetener
US8030481B2 (en) 2007-05-21 2011-10-04 The Coca-Cola Company Stevioside polymorphic and amorphous forms, methods for their formulation, and uses
AR070082A1 (es) * 2008-01-04 2010-03-10 Tate & Lyle Technology Ltd Metodo para la produccion de sucralosa
CN101236182B (zh) * 2008-01-11 2012-01-18 西北大学 三氯蔗糖中间体的分析检测方法
EP2254677A1 (de) * 2008-03-20 2010-12-01 Tate & Lyle Technology Limited Entfernung von säuren aus tertiäramid-lösungsmitteln
US8436157B2 (en) * 2008-03-26 2013-05-07 Tate & Lyle Technology Limited Method for the production of sucralose
AR071134A1 (es) * 2008-04-03 2010-05-26 Tate & Lyle Technology Ltd Cristalizacion de sucralosa a partir de chorros que contienen sucralosa
US8497367B2 (en) * 2008-04-03 2013-07-30 Tate & Lyle Technology Limited Sucralose purification process
TW200946683A (en) * 2008-04-03 2009-11-16 Tate & Lyle Technology Ltd A process for the purification of aqueous feed streams containing sucralose extraction efficiency
US20090259036A1 (en) * 2008-04-03 2009-10-15 Tate & Lyle Technology Limited Extraction of less polar impurities from sucralose containing aqueous feed streams
US20100022765A1 (en) * 2008-07-23 2010-01-28 David Losan Ho Methods for extracting and purifying sucralose intermediate
GB2468936B (en) 2009-03-27 2011-09-07 Mohamad Rami Radwan Jaber Chlorination of sucrose-6-esters
GB2469157B (en) 2009-03-30 2011-07-06 John Kerr Process for removing dimethylamine during sucralose production
GB2469158B (en) 2009-03-31 2011-09-28 Peter J Seaberg Base-assisted formation of tin-sucrose adducts
US20110027444A1 (en) * 2009-07-28 2011-02-03 Heartland Sweeteners, LLC No-calorie sweetener compositions
US20110027445A1 (en) * 2009-07-28 2011-02-03 Heartland Sweeteners, LLC No-calorie sweetener compositions
US20110027446A1 (en) * 2009-07-28 2011-02-03 Heartland Sweeteners, LLC No-calorie sweetener compositions
GB2474310B (en) 2009-10-12 2012-02-29 Tate & Lyle Technology Ltd Process for the production of sucrose-6-ester
GB2474311B (en) 2009-10-12 2012-10-17 Tate & Lyle Technology Ltd Low temperature, single solvent process for the production of sucrose-6-ester
US20120034366A1 (en) * 2010-08-05 2012-02-09 Tate & Lyle Ingredients Americas, Inc. Carbohydrate compositions
GB201110520D0 (en) 2011-05-10 2011-08-03 Tate & Lyle Technology Ltd Extraction of carboxylic acids with tin compounds
CN102391319B (zh) * 2011-10-14 2015-01-07 山东三和维信生物科技有限公司 三氯蔗糖的结晶方法
CN102391320B (zh) * 2011-12-23 2014-03-19 盐城捷康三氯蔗糖制造有限公司 溶剂热回流纯化三氯蔗糖的方法
CN102687887A (zh) * 2012-06-18 2012-09-26 陕西咸阳淳化中富实业有限公司 果蔬汁三次萃取新工艺
CN102977157A (zh) * 2012-12-05 2013-03-20 溧阳维信生物科技有限公司 一种三氯蔗糖的结晶方法
US10227367B2 (en) 2013-12-16 2019-03-12 Tate & Lyle Technology Limited Chlorination of sucrose-6-esters
WO2016020635A1 (en) 2014-08-08 2016-02-11 Tate & Lyle Technology Limited Chlorination of sucrose-6-esters
US20160115560A1 (en) * 2014-10-23 2016-04-28 Amalgamated Research Llc Methods of separating components using multi-scale simulated moving bed chromatography
CN104387427A (zh) * 2014-10-30 2015-03-04 安徽金禾实业股份有限公司 一种三氯蔗糖的生产方法
GB2536480B (en) 2015-03-17 2019-09-04 Tate & Lyle Tech Ltd DMF Distillation
JP6827048B2 (ja) * 2015-12-08 2021-02-10 バイオマトリカ，インク． 赤血球沈降速度の低下
GB2551591B (en) 2016-06-23 2019-08-07 Tate & Lyle Tech Ltd Liquid-liquid extraction of DMF
CN108264527A (zh) * 2018-01-15 2018-07-10 山东三和维信生物科技有限公司 一种提高三氯蔗糖纯度的方法
CN110527854B (zh) * 2019-09-11 2021-06-11 广东先导稀材股份有限公司 一种制备粒径可控的超高纯铼酸铵晶体的方法
CN112543760A (zh) 2020-09-30 2021-03-23 安徽金禾实业股份有限公司 三氯蔗糖的纯化方法

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA807578B (en) * 1979-12-18 1981-11-25 Tate & Lyle Patent Holdings Crystalline 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
EP0030804B1 (de) 1979-12-18 1983-10-19 TATE & LYLE PUBLIC LIMITED COMPANY Kristallin-4,1',6'-trichlor-4,1',6'-trideoxy-galactosucrose
GB2065646B (en) 1979-12-18 1983-10-05 Tate & Lyle Ltd Crystalline 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose
JPS5692898A (en) * 1979-12-20 1981-07-27 Talres Dev Manufacture of 4*1**6**trichloroo4*1**6** trideoxygalactosucrose
DE3062467D1 (en) 1979-12-20 1983-04-28 Tate & Lyle Plc Process for the preparation of 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose
ATE9355T1 (de) * 1980-07-08 1984-09-15 Tate & Lyle Public Limited Company Verfahren zur herstellung von 4,1',6'-trichlor4,1',6'-trideoxygalactosucrose (tgs).
CA1183133A (en) 1980-10-28 1985-02-26 Tate & Lyle Public Limited Company Sweet chlorine-substituted disaccharides
ZA817425B (en) * 1980-10-28 1982-10-27 Tate & Lyle Patent Holdings Sweet chlorine-substituted disaccharides
GB8525871D0 (en) 1985-10-21 1985-11-27 Tate & Lyle Plc Chemical compound
JPH0228000A (ja) * 1988-07-15 1990-01-30 Itochu Seito Kk 糖液の清浄方法
GB8822673D0 (en) 1988-09-27 1988-11-02 Tate & Lyle Plc Selective acylation of sugars
GB8822674D0 (en) 1988-09-27 1988-11-02 Tate & Lyle Plc Preparation of acylated sucrose derivatives
FR2648474B1 (fr) * 1989-06-16 1995-01-06 Roquette Freres Nouveau procede de fabrication du xylose
NZ234143A (en) 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
US4980463A (en) * 1989-07-18 1990-12-25 Noramco, Inc. Sucrose-6-ester chlorination
JPH084520B2 (ja) * 1989-11-29 1996-01-24 日本甜菜製糖株式会社 蔗糖の回収方法及び回収装置
US5034551A (en) 1990-04-23 1991-07-23 Noramco, Inc. Process for recovery of organotin esters from reaction mixtures containing the same and re-use of the recovered organotin compounds
MX9100585A (es) * 1990-08-21 1992-04-01 Warner Lambert Co Agentes edulcorantes de clorodeoxiazucar,estabilizados,en forma solida y metodos para preparar los mismos
NZ240818A (en) * 1990-12-14 1993-08-26 Mcneil Ppc Inc Liquid sucralose concentrate compositions containing preservative, buffer and liquid
US5272137A (en) 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
US5397588A (en) 1992-06-18 1995-03-14 Mcneil-Ppc, Inc. Reduced calorie fruit spreads
US5270071A (en) * 1992-06-18 1993-12-14 Mcneil-Ppc, Inc. Reduced calorie fruit spreads
US5354902A (en) 1992-10-26 1994-10-11 Mcneil-Ppc, Inc. Stabilized sorbic acid or salt thereof
CA2110313C (en) 1992-12-01 2004-10-26 Edward John Roche Pharmaceutical compositions containing a guanidinothiazole compound and antacids
CA2205535C (en) 1993-03-12 2002-01-22 Mcneil-Ppc, Inc. Sucralose pentaester production
US5530106A (en) 1993-03-12 1996-06-25 Mcneil-Ppc, Inc. Recovery of sucralose intermediates
US5298611A (en) 1993-03-12 1994-03-29 Mcneil-Ppc, Inc. Sucralose pentaester production
EP0620001A1 (de) 1993-04-16 1994-10-19 McNEIL-PPC, INC. Wässrige pharmazeutische Suspension und Verfahren zu ihrer Herstellung
CA2128820A1 (en) 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
US5674522A (en) 1993-10-07 1997-10-07 Mcneil-Ppc, Inc. Beverage concentrate for drug delivery
JPH0892273A (ja) * 1994-09-22 1996-04-09 Hokuren Federation Of Agricult Coop:The キシロシルフラクトシド結晶及びその製造方法
US5498709A (en) * 1994-10-17 1996-03-12 Mcneil-Ppc, Inc. Production of sucralose without intermediate isolation of crystalline sucralose-6-ester
US5593696A (en) 1994-11-21 1997-01-14 Mcneil-Ppc, Inc. Stabilized composition of famotidine and sucralfate for treatment of gastrointestinal disorders
JP4623763B2 (ja) * 1997-02-13 2011-02-02 テート アンド ライル テクノロジー リミテッド 塩素化スクロースのクロマトグラフィー精製
US6423358B1 (en) * 1997-04-18 2002-07-23 Mcneil-Ppc, Inc. Low calorie, palatable fiber-containing, sugar substitute
JPH11116588A (ja) * 1997-10-16 1999-04-27 Hayashibara Biochem Lab Inc トレハロース及び糖アルコールの製造方法
AU753587B2 (en) 1997-11-14 2002-10-24 Johnson & Johnson Consumer Companies, Inc. Highly flavored dental floss
US7229658B1 (en) * 1998-10-28 2007-06-12 San-Ei Gen F.F.I., Inc Compositions containing sucralose and application thereof
JP2000232900A (ja) * 1999-02-16 2000-08-29 Showa Sangyo Co Ltd 無水結晶ぶどう糖の製造方法
US6090401A (en) 1999-03-31 2000-07-18 Mcneil-Ppc, Inc. Stable foam composition
US7029717B1 (en) * 1999-04-16 2006-04-18 San-Ei Gen F.F.I., Inc. Sucralose-containing composition and edible products containing the composition
US6211246B1 (en) 1999-06-10 2001-04-03 Mcneil-Ppc, Inc. Rapidly absorbed liquid compositions
JP2001157600A (ja) * 1999-12-02 2001-06-12 Tsukishima Kikai Co Ltd 限外ろ過処理およびクロマト分離を含む甘蔗からの直接精糖法
US6258381B1 (en) 2000-02-11 2001-07-10 Mcneil-Ppc, Inc. Tablet and process for making the same
US6277409B1 (en) 2000-02-11 2001-08-21 Mcneil-Ppc, Inc. Protective coating for tablet
RU2279437C2 (ru) * 2000-11-17 2006-07-10 Тейт Энд Лайл Паблик Лимитед Компани Усовершенствованная сукралозная композиция и способ ее получения

Also Published As

Publication number Publication date
EP1487846B1 (de) 2006-01-18
CN1639179A (zh) 2005-07-13
PT1487846E (pt) 2006-05-31
DE60316853T2 (de) 2008-07-17
DK1487846T3 (da) 2006-05-22
JP4916089B2 (ja) 2012-04-11
AU2003216516B2 (en) 2009-01-08
PT1657246E (pt) 2008-01-14
CN1330659C (zh) 2007-08-08
IL163717A0 (en) 2005-12-18
AR038902A1 (es) 2005-02-02
EP1657246A1 (de) 2006-05-17
AU2008249208A1 (en) 2008-12-18
US6998480B2 (en) 2006-02-14
AU2008249184A1 (en) 2008-12-11
DK1657246T3 (da) 2008-02-11
KR101025235B1 (ko) 2011-04-01
RU2324407C2 (ru) 2008-05-20
ES2256765T3 (es) 2006-07-16
IL190247A0 (en) 2008-11-03
TW200400196A (en) 2004-01-01
ES2296057T3 (es) 2008-04-16
AU2008249188A1 (en) 2008-12-11
KR20040099306A (ko) 2004-11-26
WO2003076454A1 (en) 2003-09-18
ATE375357T1 (de) 2007-10-15
MXPA04009925A (es) 2005-07-01
DE60316853D1 (de) 2007-11-22
CA2481402A1 (en) 2003-09-18
EP1657246B1 (de) 2007-10-10
BR0308292A (pt) 2005-01-11
AU2003216516A1 (en) 2003-09-22
AU2008249185A1 (en) 2008-12-11
ATE316092T1 (de) 2006-02-15
AU2008249186A1 (en) 2008-12-11
RU2004129750A (ru) 2005-04-20
DE60303305T2 (de) 2006-09-21
EP1487846A1 (de) 2004-12-22
US20030171575A1 (en) 2003-09-11
AU2003216516A2 (en) 2003-09-22
JP2005526767A (ja) 2005-09-08

Similar Documents

Publication Publication Date Title
DE60303305D1 (de) Verfahren zur verbesserung der reinheit und ausbeute von sucralose
ATE540962T1 (de) Extraktive verfahren zur aufreinigung von sucralose
ATE500824T1 (de) Verfahren zur reinigung von trans-(-)-delta9- tetrahydrocannabinol und trans-(+)-delta9- tetrahydrocannabinol
DE602004031106D1 (de) Verfahren und vorrichtung zur verfestigung von glas
DE60321566D1 (de) Verfahren und Dichtmittel zum Verbinden
DE60329738D1 (de) Verfahren und System zum Drucken von integrierten Schaltungsplänen
DE60332591D1 (de) Verfahren und Vorrichtung zur doppelten Kennzeichnung von Datenpaketen
DE60321130D1 (de) Variation von parametern zur neurostimulation
DE60326012D1 (de) Verfahren zur Konzentration von Proteinen
DE60231600D1 (de) Verfahren und anlage zur trennung und rückgewinnung von halogengas
DE50312932D1 (de) Verfahren und schaltungsanordnung zum begrenzen einer überspannung
DE60321938D1 (de) Zusammensetzung zur schleimvermeidung und verfahren zur schleimvermeidung
DE10295684T1 (de) Verfahren zum spezifischen Hemmen von Histon-Deacetylase-4
DE50303241D1 (de) Verfahren zur bereitstellung von abwesenheitsinformation
DE60301147D1 (de) RC4 Verfahren zur Verschlüsselung von Paketen
DE60321824D1 (de) System und verfahren zur minimierung der modulationsinstabilität
DE50312128D1 (de) Lenkung und Verfahren zur Lenkung
DE60318432D1 (de) Verfahren und vorrichtungen zum umsetzen von farbwerten
ATA4522002A (de) Verfahren zur erkennung von geisterfahrern
ATA9292003A (de) Verfahren zur bildung wenigstens eines kohärenten gasstrahles und kohärentstrahlenlanze
DE602004012134D1 (de) Verfahren und system zur unterstützung des betriebs von arbeitszügen
ATE459599T1 (de) Gereinigtes lasofoxifen und verfahren zur aufreinigung von racemischem lasofoxifen durch umkristallisieren
DE60315255D1 (de) Zusammensetzung und verfahren zur bekämpfung von termiten
DE10393758D2 (de) Photodetektor-Anordnung und Verfahren zur Störlichtkompensation
DE60303877D1 (de) Verfahren zur Rückgewinnung von Phenol und Biphenolen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: TATE & LYLE TECHNOLOGY LTD., LONDON, GB

8339 Ceased/non-payment of the annual fee