DE60230886D1 - Systeme, verfahren und geräte zur herstellung von dosierungsformen - Google Patents

Systeme, verfahren und geräte zur herstellung von dosierungsformen

Info

Publication number
DE60230886D1
DE60230886D1 DE60230886T DE60230886T DE60230886D1 DE 60230886 D1 DE60230886 D1 DE 60230886D1 DE 60230886 T DE60230886 T DE 60230886T DE 60230886 T DE60230886 T DE 60230886T DE 60230886 D1 DE60230886 D1 DE 60230886D1
Authority
DE
Germany
Prior art keywords
dosage form
systems
methods
devices
dosage forms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60230886T
Other languages
English (en)
Inventor
Harry S Sowden
Shun-Por Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson Consumer Inc
Original Assignee
McNeil PPC Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McNeil PPC Inc filed Critical McNeil PPC Inc
Application granted granted Critical
Publication of DE60230886D1 publication Critical patent/DE60230886D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/02—Apparatus specially adapted for manufacture or treatment of sweetmeats or confectionery; Accessories therefor
    • A23G3/04—Sugar-cookers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G3/368—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing vitamins, antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/005—Coating of tablets or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/34—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses for coating articles, e.g. tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2873—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
DE60230886T 2001-09-28 2002-09-26 Systeme, verfahren und geräte zur herstellung von dosierungsformen Expired - Lifetime DE60230886D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/966,939 US6837696B2 (en) 2001-09-28 2001-09-28 Apparatus for manufacturing dosage forms
PCT/US2002/030614 WO2003028990A1 (en) 2001-09-28 2002-09-26 Systems, methods and apparatuses for manufacturing dosage forms

Publications (1)

Publication Number Publication Date
DE60230886D1 true DE60230886D1 (de) 2009-03-05

Family

ID=25512088

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60230886T Expired - Lifetime DE60230886D1 (de) 2001-09-28 2002-09-26 Systeme, verfahren und geräte zur herstellung von dosierungsformen

Country Status (17)

Country Link
US (3) US6837696B2 (de)
EP (1) EP1429915B1 (de)
JP (1) JP2005504639A (de)
KR (1) KR100861670B1 (de)
CN (2) CN100488763C (de)
AT (1) ATE420762T1 (de)
AU (1) AU2002337711B2 (de)
CA (1) CA2462008C (de)
DE (1) DE60230886D1 (de)
ES (1) ES2319971T3 (de)
HU (1) HUP0401653A2 (de)
MX (1) MXPA04002971A (de)
NO (1) NO20041716L (de)
NZ (1) NZ532095A (de)
PL (1) PL369169A1 (de)
WO (1) WO2003028990A1 (de)
ZA (2) ZA200403166B (de)

Families Citing this family (118)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US20040146559A1 (en) * 2002-09-28 2004-07-29 Sowden Harry S. Dosage forms having an inner core and outer shell with different shapes
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
BR0212950A (pt) * 2001-09-28 2004-10-26 Mcneil Ppc Inc Formas de dosagens compósitas tendo uma porção inserida
US7217381B2 (en) * 2001-09-28 2007-05-15 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US6837696B2 (en) * 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
US7807197B2 (en) * 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
ITMO20030122A1 (it) * 2003-04-30 2004-11-01 Sacmi Apparato e metodo per allontanare oggetti da mezzi formatori.
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004032051A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
GB0322358D0 (en) * 2003-09-24 2003-10-22 Bioprogress Technology Ltd Improvements in powder compaction and enrobing
ITMO20030289A1 (it) * 2003-10-23 2005-04-24 Sacmi Apparati, metodo e articolo.
US8067029B2 (en) 2004-01-13 2011-11-29 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US7879354B2 (en) * 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US20050196446A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
US20050196447A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
US20050196448A1 (en) * 2004-03-05 2005-09-08 Hai Yong Huang Polymeric compositions and dosage forms comprising the same
US20050196442A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
US7178562B2 (en) * 2004-04-08 2007-02-20 Graham Packaging Pet Technologies Inc. Pellet transfer apparatus and method
US20050281876A1 (en) 2004-06-18 2005-12-22 Shun-Por Li Solid dosage form for acid-labile active ingredient
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
EP1944005A3 (de) * 2004-09-24 2008-07-23 BioProgress Technology Limited Zusätzliche Verbesserungen bei der Pulverpressung und -ummantelung
EP1807040A1 (de) * 2004-09-24 2007-07-18 BioProgress Technology Limited Zusätzliche verbesserungen bei der pulverkompaktierung und umhüllung
US20070281022A1 (en) * 2004-10-27 2007-12-06 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US8383159B2 (en) * 2004-10-27 2013-02-26 Mcneil-Ppc, Inc. Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060087051A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088586A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088593A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20070190133A1 (en) * 2004-10-27 2007-08-16 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088587A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
KR100597182B1 (ko) 2004-10-29 2006-07-05 한영수 골반저근육 강화용 콘의 성형장치
US7530804B2 (en) * 2004-12-07 2009-05-12 Mcneil-Ppc, Inc. System and process for providing at least one opening in dosage forms
US7404708B2 (en) * 2004-12-07 2008-07-29 Mcneil-Ppc, Inc. System and process for providing at least one opening in dosage forms
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US9579238B2 (en) 2005-02-17 2017-02-28 The Procter & Gamble Company Sanitary napkins capable of taking complex three-dimensional shape in use
US8211078B2 (en) 2005-02-17 2012-07-03 The Procter And Gamble Company Sanitary napkins capable of taking complex three-dimensional shape in use
US20060233882A1 (en) * 2005-04-15 2006-10-19 Sowden Harry S Osmotic dosage form
US8673352B2 (en) * 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
US20070048366A1 (en) * 2005-08-26 2007-03-01 Jen-Chi Chen Gelatin-based coatings having improved durability
US20070077300A1 (en) * 2005-09-30 2007-04-05 Wynn David W Oral compositions containing a salivation inducing agent
US8106100B2 (en) * 2005-12-06 2012-01-31 Asahi Kasei Chemicals Corporation Process for producing tablet by high-speed direct compression
DE102005061787A1 (de) * 2005-12-23 2007-06-28 Fette Gmbh Vorrichtung zur Erzeugung eines Unterdrucks im abgedichteten Raum einer Tablettenpresse und/oder eines Isolators
JP5529529B2 (ja) 2006-04-05 2014-06-25 インターコンチネンタル グレート ブランズ エルエルシー 口腔輸送システムに用いるリン酸カルシウム錯体及び塩
BRPI0710844A2 (pt) * 2006-04-05 2011-08-23 Cadbury Adams Usa Llc composição de confeito , método e kit de remineralizar e de conferir resistência a ácido a superficie dos dentes de um mamìfero
RU2437652C2 (ru) * 2006-04-05 2011-12-27 КЭДБЕРИ АДАМС ЮЭсЭй ЛЛС Воздействие кальцийфосфатного комплекса на зубной кариес
US7630787B2 (en) * 2006-04-19 2009-12-08 Husky Injection Molding Systems Ltd System for integrating insert with molded article
FI20070521L (fi) * 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
US8951562B2 (en) * 2006-11-10 2015-02-10 Atacama Labs Oy Method and apparatus or dry granulation
FI20060990A0 (fi) * 2006-11-10 2006-11-10 Iprbox Oy Rakeita, tabletteja ja rakeistusmenetelmä
EP1952696A1 (de) * 2007-02-01 2008-08-06 Nestec S.A. Verfahren und Vorrichtung zur Herstellung von im Zentrum gefüllten, geformten Lebensmittelprodukten
DE102007011485A1 (de) 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
TWI414322B (zh) * 2007-04-26 2013-11-11 Eisai R&D Man Co Ltd Preparation of lozenges
EP2155167A2 (de) 2007-06-04 2010-02-24 Egalet A/S Pharmazeutische zusammensetzungen mit gesteuerter freisetzung für verlängerte wirkung
US8002823B2 (en) * 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
JP5098535B2 (ja) * 2007-09-21 2012-12-12 東洋製罐株式会社 溶融樹脂供給装置
US7867418B2 (en) * 2007-09-24 2011-01-11 Mars, Incorporated Tool and apparatus for forming a moldable material
NZ586792A (en) 2008-01-25 2012-09-28 Gruenenthal Chemie Tamper resistant controlled release pharmaceutical tablets form having convex and concave surfaces
BRPI0912014A2 (pt) 2008-05-09 2019-03-06 Grünenthal GmbH processo para a preparação de uma formulação em pó intermediária e uma forma de dosagem sólida final sob uso de uma etapa de congelamento por atomização
WO2009135946A1 (en) * 2008-05-09 2009-11-12 Atacama Labs Oy Method and apparatus for dry granulation
US8382921B1 (en) * 2008-09-11 2013-02-26 The United States Of America As Represented By The Secretary Of The Navy Apparatus for making miniature explosive powder charges
US8328966B1 (en) * 2008-09-11 2012-12-11 The United States Of America As Represented By The Secretary Of The Navy Method for making miniature explosive powder charges
IT1394597B1 (it) * 2008-11-05 2012-07-05 Politi Granulazione a secco in flusso di gas.
US9005660B2 (en) 2009-02-06 2015-04-14 Egalet Ltd. Immediate release composition resistant to abuse by intake of alcohol
US20100255084A1 (en) * 2009-04-06 2010-10-07 Yoel Ovil Medicinal melting capsules for oral mucosal absorption
US20100255086A1 (en) * 2009-04-06 2010-10-07 Yoel Ovil Method for oral mucosal absorption of acetyl salycylic acid
US20100255088A1 (en) * 2009-04-06 2010-10-07 Yoel Ovil Method for delivering a combination of resveratrol and aspirin for use in treatment and prevention of vascular disease
NZ603579A (en) 2009-06-24 2014-02-28 Egalet Ltd Controlled release formulations
CA2765971C (en) 2009-07-22 2017-08-22 Gruenenthal Gmbh Hot-melt extruded controlled release dosage form
ES2718688T3 (es) 2009-07-22 2019-07-03 Gruenenthal Gmbh Forma de dosificación resistente a la manipulación para opioides sensibles a la oxidación
US8343533B2 (en) 2009-09-24 2013-01-01 Mcneil-Ppc, Inc. Manufacture of lozenge product with radiofrequency
NZ608865A (en) 2010-09-02 2015-03-27 Gruenenthal Chemie Tamper resistant dosage form comprising an anionic polymer
PE20131102A1 (es) 2010-09-02 2013-10-12 Gruenenthal Chemie Forma de dosificacion resistente a manipulacion que comprende una sal inorganica
SI2736497T1 (sl) 2011-07-29 2017-12-29 Gruenenthal Gmbh Tableta, odporna proti zlorabi, ki zagotavlja takojšnje sproščanje zdravila
EP2736495B1 (de) 2011-07-29 2017-08-23 Grünenthal GmbH Verfälschungssichere multipartikular-tablette, die eine sofortige wirkstofffreigabe bereitstellt
JP6126605B2 (ja) * 2011-08-24 2017-05-10 ユニリーバー・ナームローゼ・ベンノートシヤープ 非イオン性多糖を含む有益剤送達粒子
JP6117249B2 (ja) 2012-02-28 2017-04-19 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 薬理学的に活性な化合物および陰イオン性ポリマーを含むタンパーレジスタント剤形
JP6282261B2 (ja) 2012-04-18 2018-02-21 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 不正使用防止および過量放出防止医薬剤形
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
US9445971B2 (en) 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
US9233491B2 (en) 2012-05-01 2016-01-12 Johnson & Johnson Consumer Inc. Machine for production of solid dosage forms
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
EP2857006A4 (de) 2012-06-05 2015-12-30 Takeda Pharmaceutical Trockenbeschichtete tablette
US8399011B1 (en) * 2012-08-10 2013-03-19 Magnifica Inc. Oral particle compositions containing a core and an acid-soluble coat
MX371432B (es) 2013-05-29 2020-01-30 Gruenenthal Gmbh Forma de dosificacion resistente al uso indebido que contiene una o mas particulas.
AR096439A1 (es) 2013-05-29 2015-12-30 Gruenenthal Gmbh Forma de dosificación resistente al uso indebido que contiene una o más partículas
JP6449871B2 (ja) 2013-07-12 2019-01-09 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング エチレン−酢酸ビニルポリマーを含有する改変防止剤形
US20150093439A1 (en) * 2013-09-27 2015-04-02 Mcneil-Ppc, Inc. Compression coated pulsatile release compositions
WO2015078891A1 (en) 2013-11-26 2015-06-04 Farmaceutici Formenti S.P.A. Preparation of a powdery pharmaceutical composition by means of cryo-milling
JP6075278B2 (ja) * 2013-12-05 2017-02-08 株式会社デンソー プレス加工装置
MX368159B (es) 2014-01-10 2019-09-20 Johnson & Johnson Consumer Inc Proceso para elaborar tabletas con el uso de radiofrecuencia y partículas disipativas revestidas.
EP3142646A1 (de) 2014-05-12 2017-03-22 Grünenthal GmbH Manipulationssichere kapselformulierung mit tapentadol mit unmittelbarer freisetzung
JP2017516789A (ja) 2014-05-26 2017-06-22 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング エタノール過量放出に対して防護されている多粒子
KR20160126217A (ko) 2015-04-23 2016-11-02 주식회사 진명 에프 엠 씨 용기 투입장치
BR112017021475A2 (pt) 2015-04-24 2018-07-10 Gruenenthal Gmbh forma de dosagem resistente à adulteração (tamper) com liberação imediata e resistência contra extração de solvente
TWI580310B (zh) * 2015-08-14 2017-04-21 Bottle-Top Dev Co Microwave heating system
CN107921471B (zh) 2015-08-21 2023-05-23 阿普雷奇亚制药有限责任公司 三维打印系统和设备组件
JP2018526414A (ja) 2015-09-10 2018-09-13 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護
ITUB20154653A1 (it) 2015-10-14 2017-04-14 Sacmi Apparato e metodo per processare dosi.
ES2747984T3 (es) * 2016-03-24 2020-03-12 Korsch Ag Prensa rotatoria con sellos, con al menos dos puntas de sello a alturas escalonadas, para realizar múltiples procesos de prensado durante una rotación
CN106166849A (zh) * 2016-08-24 2016-11-30 海宁艾迪欧动物保健品科技有限公司 一种自动上料的中药材压饼装置
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
CN107028901A (zh) * 2017-03-29 2017-08-11 陈永雷 一种药品含片、功能性食品含片、保健食品含片区域分区制备法
CN107041845B (zh) * 2017-05-05 2023-05-23 杨超翔 儿童给药装置及方法
ES2975449T3 (es) 2017-05-22 2024-07-05 Johnson & Johnson Consumer Inc Forma farmacéutica de pastilla
CN108158816B (zh) * 2018-01-18 2021-01-19 广东省惠州市中药厂有限公司 根茎类药材提取制粒设备及提取方法
GB2578272B (en) * 2018-07-10 2023-03-29 Innopharma Res Limited Apparatus and method for the production of solid dosage forms
ES2930199T3 (es) 2018-10-15 2022-12-07 Aprecia Pharmaceuticals LLC Método y sistema para formar una forma farmacéutica dentro de un envase
US11413839B2 (en) * 2018-12-14 2022-08-16 Natoli Engineering Company, Inc. Device to level a feeder platform
DE102019210354B4 (de) * 2019-07-12 2024-06-06 Theegarten-Pactec Gmbh & Co. Kg Rotationskopf mit rotierenden Arbeitsstationen
IT202000012685A1 (it) * 2020-05-28 2021-11-28 Perfetti Van Melle Spa Metodo per la realizzazione di un prodotto compresso
US12125574B2 (en) * 2020-08-28 2024-10-22 Omnicell, Inc. Systems and methods for parallel preparation processing
CN112590291B (zh) * 2020-12-04 2022-07-22 重庆医药高等专科学校 一种制药用压片装置
CN113002046B (zh) * 2021-03-03 2021-12-14 林美珊 一种螺旋挤压式固液分离机
CN115581262B (zh) * 2022-09-08 2024-07-19 广州麟威健康科技股份有限公司 一种运动营养食品自动成型装置

Family Cites Families (159)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US599865A (en) * 1898-03-01 Emanuel l
US124183A (en) * 1872-02-27 Improvement in packings for engines
US86973A (en) * 1869-02-16 Improvement in tarn-guide and clearer
US2307371A (en) * 1941-08-13 1943-01-05 Ray O Vac Co Molding process
US2386173A (en) * 1943-05-13 1945-10-02 American Viscose Corp Apparatus for the production of artificial filaments
US2996431A (en) * 1953-12-16 1961-08-15 Barry Richard Henry Friable tablet and process for manufacturing same
US2849965A (en) * 1954-04-15 1958-09-02 John Holroyd & Company Ltd Machines for use in the production of coated tablets and the like
GB759081A (en) 1954-04-15 1956-10-10 John Holroyd And Company Ltd Improvements relating to machines for the production of coated tablets and the like
US2946298A (en) * 1957-11-13 1960-07-26 Arthur Colton Company Compression coating tablet press
DE1155348B (de) 1958-11-13 1963-10-03 Tatra Np Pneumatische Betaetigungsvorrichtung zum Umschalten eines Stufenwechselgetriebes, insbesondere fuer Kraftfahrzeuge
GB936386A (en) 1959-01-16 1963-09-11 Wellcome Found Pellets for supplying biologically active substances to ruminants
US3096248A (en) * 1959-04-06 1963-07-02 Rexall Drug & Chemical Company Method of making an encapsulated tablet
GB972128A (en) * 1960-01-21 1964-10-07 Wellcome Found Pellets for supplying biologically active substances to ruminants and the manufacture of such pellets
GB994742A (en) 1960-09-09 1965-06-10 Wellcome Found Pharmaceutical tablets containing anthelmintics, and the manufacture thereof
BE611639A (de) * 1960-12-28
BE636865A (de) * 1962-08-31
GB1144915A (en) 1966-11-24 1969-03-12 Armour Pharma Improvements in or relating to pastille formulations
US3627583A (en) * 1969-04-29 1971-12-14 Sucrest Corp Direct compression vehicles
US3832252A (en) * 1970-09-29 1974-08-27 T Higuchi Method of making a drug-delivery device
CH569482A5 (de) 1970-12-23 1975-11-28 Boehringer Sohn Ingelheim
US3726622A (en) * 1971-08-20 1973-04-10 Wolverine Pentronix Compacting apparatus
DE2157465C3 (de) * 1971-11-19 1975-04-24 Werner & Pfleiderer, 7000 Stuttgart Füllvorrichtung für eine hydraulische Blockpresse
US4139589A (en) * 1975-02-26 1979-02-13 Monique Beringer Process for the manufacture of a multi-zone tablet and tablet manufactured by this process
US4230693A (en) * 1975-04-21 1980-10-28 Armour-Dial, Inc. Antacid tablets and processes for their preparation
US4097606A (en) * 1975-10-08 1978-06-27 Bristol-Myers Company APAP Tablet containing an alkali metal carboxymethylated starch and processes for manufacturing same
SE414386B (sv) 1976-03-10 1980-07-28 Aco Laekemedel Ab Sett att framstella och samtidigt forpacka farmaceutiska dosenheter
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
US4139627A (en) * 1977-10-06 1979-02-13 Beecham Inc. Anesthetic lozenges
GB2030042A (en) * 1978-09-21 1980-04-02 Beecham Group Ltd Antacid fondant
US4173626A (en) * 1978-12-11 1979-11-06 Merck & Co., Inc. Sustained release indomethacin
NL7906689A (nl) * 1979-09-06 1981-03-10 Dawsonville Corp Nv Tatoueerinrichting.
US4273793A (en) * 1979-10-26 1981-06-16 General Foods Corporation Apparatus and process for the preparation of gasified confectionaries by pressurized injection molding
US4271206A (en) * 1979-10-26 1981-06-02 General Foods Corporation Gasified candy having a predetermined shape
US4473526A (en) * 1980-01-23 1984-09-25 Eugen Buhler Method of manufacturing dry-pressed molded articles
US4292017A (en) * 1980-07-09 1981-09-29 Doepel Wallace A Apparatus for compressing tablets
US4362757A (en) * 1980-10-22 1982-12-07 Amstar Corporation Crystallized, readily water dispersible sugar product containing heat sensitive, acidic or high invert sugar substances
US5002970A (en) * 1981-07-31 1991-03-26 Eby Iii George A Flavor masked ionizable zinc compositions for oral absorption
IE53102B1 (en) * 1981-05-12 1988-06-22 Ici Plc Pharmaceutical spiro-succinimide derivatives
US4372942A (en) * 1981-08-13 1983-02-08 Beecham Inc. Candy base and liquid center hard candy made therefrom
DE3144678A1 (de) * 1981-11-10 1983-05-19 Eugen Dipl.-Ing. 8871 Burtenbach Bühler Verfahren und einrichtung zur herstellung von formlingen aus einer rieselfaehigen masse
JPS58152813A (ja) 1982-03-08 1983-09-10 Sumitomo Chem Co Ltd 鮮明な刻印を有する錠剤およびその製法
US4516335A (en) * 1982-04-09 1985-05-14 Sanyo Electric Co., Ltd. Clothes dryer
DK151608C (da) * 1982-08-13 1988-06-20 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse
US4517205A (en) * 1983-01-03 1985-05-14 Nabisco Brands, Inc. Co-deposited two-component hard candy
US4882167A (en) * 1983-05-31 1989-11-21 Jang Choong Gook Dry direct compression compositions for controlled release dosage forms
US4749575A (en) * 1983-10-03 1988-06-07 Bio-Dar Ltd. Microencapsulated medicament in sweet matrix
US4781714A (en) * 1983-11-02 1988-11-01 Alza Corporation Dispenser for delivering thermo-responsive composition
DE3404108A1 (de) * 1984-02-07 1985-08-14 Kilian & Co GmbH, 5000 Köln Tablettenpresse
US4518335A (en) 1984-03-14 1985-05-21 Allied Corporation Dilatant mold and dilatant molding apparatus
JPS60217106A (ja) * 1984-04-12 1985-10-30 高橋　信之 無機粉末凍結成形法
US4661521A (en) * 1984-04-30 1987-04-28 Mallinckrodt, Inc. Direct tableting acetaminophen compositions
US4874614A (en) * 1985-03-25 1989-10-17 Abbott Laboratories Pharmaceutical tableting method
GB8517073D0 (en) * 1985-07-05 1985-08-14 Hepworth Iron Co Ltd Pipe pipe couplings &c
DK8603837A (de) * 1985-08-13 1987-02-14
US5188840A (en) * 1985-09-26 1993-02-23 Chugai Seiyaku Kabushiki Kaisha Slow-release pharmaceutical agent
US4898733A (en) * 1985-11-04 1990-02-06 International Minerals & Chemical Corp. Layered, compression molded device for the sustained release of a beneficial agent
US5229164A (en) * 1985-12-19 1993-07-20 Capsoid Pharma Gmbh Process for producing individually dosed administration forms
US4764378A (en) * 1986-02-10 1988-08-16 Zetachron, Inc. Buccal drug dosage form
DE3610878A1 (de) 1986-04-01 1987-10-08 Boehringer Ingelheim Kg Formlinge aus pellets
IE58401B1 (en) * 1986-06-20 1993-09-08 Elan Corp Plc Controlled absorption pharmaceutical composition
US4757090A (en) * 1986-07-14 1988-07-12 Mallinckrodt, Inc. Direct tableting acetaminophen compositions
US4762719A (en) * 1986-08-07 1988-08-09 Mark Forester Powder filled cough product
CA1290526C (en) * 1986-11-07 1991-10-15 Marianne Wieser Mold and die operation
DE3640574A1 (de) 1986-11-27 1988-06-09 Katjes Fassin Gmbh & Co Kg Verfahren zur herstellung eines essbaren pralinenfoermigen produktes und vorrichtung fuer die durchfuehrung des verfahrens
US4820524A (en) * 1987-02-20 1989-04-11 Mcneilab, Inc. Gelatin coated caplets and process for making same
US4792448A (en) 1987-06-11 1988-12-20 Pfizer Inc. Generic zero order controlled drug delivery system
US4813818A (en) * 1987-08-25 1989-03-21 Michael Sanzone Apparatus and method for feeding powdered materials
US4851226A (en) * 1987-11-16 1989-07-25 Mcneil Consumer Products Company Chewable medicament tablet containing means for taste masking
US4894236A (en) * 1988-01-12 1990-01-16 Choong-Gook Jang Direct compression tablet binders for acetaminophen
US4929446A (en) * 1988-04-19 1990-05-29 American Cyanamid Company Unit dosage form
DE3822095A1 (de) * 1988-06-30 1990-01-04 Klinge Co Chem Pharm Fab Neue arzneimittelformulierung sowie verfahren zu deren herstellung
DE3830353A1 (de) * 1988-09-07 1990-03-15 Basf Ag Verfahren zur kontinuierlichen herstellung von festen pharmazeutischen formen
US4906478A (en) * 1988-12-12 1990-03-06 Valentine Enterprises, Inc. Simethicone/calcium silicate composition
US4984240A (en) * 1988-12-22 1991-01-08 Codex Corporation Distributed switching architecture for communication module redundancy
US5032406A (en) * 1989-02-21 1991-07-16 Norwich Eaton Pharmaceuticals, Inc. Dual-action tablet
US4990535A (en) * 1989-05-03 1991-02-05 Schering Corporation Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine
US5146730A (en) * 1989-09-20 1992-09-15 Banner Gelatin Products Corp. Film-enrobed unitary-core medicament and the like
DK469989D0 (da) * 1989-09-22 1989-09-22 Bukh Meditec Farmaceutisk praeparat
US5275822A (en) * 1989-10-19 1994-01-04 Valentine Enterprises, Inc. Defoaming composition
US5169645A (en) * 1989-10-31 1992-12-08 Duquesne University Of The Holy Ghost Directly compressible granules having improved flow properties
FR2655266B1 (fr) * 1989-12-05 1992-04-03 Smith Kline French Lab Compositions pharmaceutiques a base de cimetidine.
US5223266A (en) * 1990-01-24 1993-06-29 Alza Corporation Long-term delivery device with early startup
US5158777A (en) * 1990-02-16 1992-10-27 E. R. Squibb & Sons, Inc. Captopril formulation providing increased duration of activity
JP2801728B2 (ja) * 1990-03-13 1998-09-21 フロイント産業株式会社 糖衣製品及びその製造方法
US4980169A (en) * 1990-05-03 1990-12-25 Warner-Lambert Company Flavor enhancing and increasing efficacy of cough drops
US4983394A (en) * 1990-05-03 1991-01-08 Warner-Lambert Company Flavor enhancing and medicinal taste masking agent
US5213738A (en) * 1990-05-15 1993-05-25 L. Perrigo Company Method for making a capsule-shaped tablet
US5089270A (en) * 1990-05-15 1992-02-18 L. Perrigo Company Capsule-shaped tablet
US5075114A (en) * 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
EP0461547A1 (de) 1990-06-15 1991-12-18 Swatch Ag Uhr mit am Armband befestigten Zeitzonenanzeigeelement und Satz derselben Elemente zur Ausrüstung einer solchen Uhr
US5464631A (en) * 1990-06-27 1995-11-07 Warner-Lambert Company Encapsulated dosage forms
US5228916A (en) * 1990-11-05 1993-07-20 Mcneil-Ppc, Inc. Apparatus for creating a gelatin coating
US5436026A (en) * 1990-11-05 1995-07-25 Mcneil-Ppc, Inc. Discharge and transfer system for apparatus for gelatin coating tablets
US5503673A (en) * 1990-11-05 1996-04-02 Mcneil-Ppc, Inc Apparatus for dip coating product
US5538125A (en) * 1990-11-05 1996-07-23 Mcneil-Ppc, Inc. Indexing and feeding systems for apparatus for gelatin coating tablets
US5378475A (en) 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
NZ241613A (en) * 1991-02-27 1993-06-25 Janssen Pharmaceutica Nv Highlighting intagliations in tablets
US5286497A (en) * 1991-05-20 1994-02-15 Carderm Capital L.P. Diltiazem formulation
CA2068402C (en) * 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
US5326570A (en) * 1991-07-23 1994-07-05 Pharmavene, Inc. Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine
US5200191A (en) * 1991-09-11 1993-04-06 Banner Gelatin Products Corp. Softgel manufacturing process
US5200195A (en) * 1991-12-06 1993-04-06 Alza Corporation Process for improving dosage form delivery kinetics
US5579338A (en) * 1992-06-29 1996-11-26 Mitsubishi Denki Kabushiki Kaisha Spread spectrum receiver using partial correlations
US5317849A (en) * 1992-08-07 1994-06-07 Sauter Manufacturing Corporation Encapsulation equipment and method
IT1255522B (it) * 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
WO1994007470A1 (en) 1992-09-30 1994-04-14 Pfizer Inc. Article containing a core and a coating having a non constant thickness
TW272942B (de) * 1993-02-10 1996-03-21 Takeda Pharm Industry Co Ltd
US5391378A (en) * 1993-02-22 1995-02-21 Elizabeth-Hata International, Inc. Two-part medicinal tablet and method of manufacture
JP2524955B2 (ja) * 1993-04-22 1996-08-14 トーワ株式会社 電子部品の樹脂封止成形方法及び装置
EP0621032B1 (de) * 1993-04-23 2000-08-09 Novartis AG Wirkstoffabgabevorrichtung mit gesteuerter Freigabe
US5415868A (en) * 1993-06-09 1995-05-16 L. Perrigo Company Caplets with gelatin cover and process for making same
ZA944949B (en) 1993-07-12 1995-04-05 Smithkline Beecham Corp Matrix-entrapped beadlet preparation
US5622719A (en) * 1993-09-10 1997-04-22 Fuisz Technologies Ltd. Process and apparatus for making rapidly dissolving dosage units and product therefrom
US5397574A (en) * 1993-10-04 1995-03-14 Andrx Pharmaceuticals, Inc. Controlled release potassium dosage form
DE4341442C2 (de) * 1993-12-04 1998-11-05 Lohmann Therapie Syst Lts Vorrichtung zur kontrollierten Freisetzung von Wirkstoffen sowie ihre Verwendung
IT1274034B (it) * 1994-07-26 1997-07-14 Applied Pharma Res Composizioni farmaceutiche a base di gomma da masticare e procedimento per la loro preparazione
US5614578A (en) * 1994-10-28 1997-03-25 Alza Corporation Injection-molded dosage form
DE4446468A1 (de) * 1994-12-23 1996-06-27 Basf Ag Verfahren zur Herstellung von umhüllten Tabletten
US5558879A (en) * 1995-04-28 1996-09-24 Andrx Pharmaceuticals, Inc. Controlled release formulation for water soluble drugs in which a passageway is formed in situ
CN1183715A (zh) * 1995-05-09 1998-06-03 科洛康有限公司 适合药物基质静电包衣的粉末包衣物质
US5686106A (en) * 1995-05-17 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form for colonic delivery
US5578336A (en) 1995-06-07 1996-11-26 Monte; Woodrow C. Confection carrier for vitamins, enzymes, phytochemicals and ailmentary vegetable compositions and method of making
US6185356B1 (en) 1995-06-27 2001-02-06 Lumitex, Inc. Protective cover for a lighting device
US5614207A (en) * 1995-06-30 1997-03-25 Mcneil-Ppc, Inc. Dry mouth lozenge
GB9517031D0 (en) 1995-08-19 1995-10-25 Procter & Gamble Confection compositions
DE19539361A1 (de) 1995-10-23 1997-04-24 Basf Ag Verfahren zur Herstellung von mehrschichtigen, festen Arzneiformen zur oralen oder rektalen Verabreichung
US5807579A (en) * 1995-11-16 1998-09-15 F.H. Faulding & Co. Limited Pseudoephedrine combination pharmaceutical compositions
IT1282576B1 (it) 1996-02-06 1998-03-31 Jagotec Ag Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili
US5824338A (en) * 1996-08-19 1998-10-20 L. Perrigo Company Caplet and gelatin covering therefor
US5972389A (en) * 1996-09-19 1999-10-26 Depomed, Inc. Gastric-retentive, oral drug dosage forms for the controlled-release of sparingly soluble drugs and insoluble matter
DE19710213A1 (de) * 1997-03-12 1998-09-17 Basf Ag Verfahren zur Herstellung von festen Kombinationsarzneiformen
US5837301A (en) * 1997-04-28 1998-11-17 Husky Injection Molding Systems Ltd. Injection molding machine having a high speed turret
US6149939A (en) * 1997-05-09 2000-11-21 Strumor; Mathew A. Healthful dissolvable oral tablets, and mini-bars
DE59812488D1 (de) 1997-07-09 2005-02-17 Swiss Caps Rechte & Lizenzen Verfahren und vorrichtung zum herstellen einer mehrschichtigen, physiologisch verträglichen darreichungsform
US6103260A (en) * 1997-07-17 2000-08-15 Mcneil-Ppc, Inc. Simethicone/anhydrous calcium phosphate compositions
US5942034A (en) * 1997-07-24 1999-08-24 Bayer Corporation Apparatus for the gelatin coating of medicaments
US6432442B1 (en) 1998-02-23 2002-08-13 Mcneil-Ppc, Inc. Chewable product
US6365185B1 (en) * 1998-03-26 2002-04-02 University Of Cincinnati Self-destructing, controlled release peroral drug delivery system
US6372254B1 (en) 1998-04-02 2002-04-16 Impax Pharmaceuticals Inc. Press coated, pulsatile drug delivery system suitable for oral administration
US6365183B1 (en) 1998-05-07 2002-04-02 Alza Corporation Method of fabricating a banded prolonged release active agent dosage form
JP5048177B2 (ja) 1998-05-15 2012-10-17 中外製薬株式会社 放出制御製剤
US6103257A (en) * 1998-07-17 2000-08-15 Num-Pop, Inc. System for delivering pharmaceuticals to the buccal mucosa
US6200590B1 (en) * 1998-08-10 2001-03-13 Naphcare, Inc. Controlled, phased-release suppository and its method of production
DE19840256A1 (de) * 1998-09-03 2000-03-09 Basf Ag Verfahren zur Herstellung von beschichteten festen Dosierungsformen
US5997905A (en) * 1998-09-04 1999-12-07 Mcneil-Ppc Preparation of pharmaceutically active particles
US6174547B1 (en) * 1999-07-14 2001-01-16 Alza Corporation Dosage form comprising liquid formulation
US6602521B1 (en) 1998-09-29 2003-08-05 Impax Pharmaceuticals, Inc. Multiplex drug delivery system suitable for oral administration
US6322819B1 (en) * 1998-10-21 2001-11-27 Shire Laboratories, Inc. Oral pulsed dose drug delivery system
US6270805B1 (en) * 1998-11-06 2001-08-07 Andrx Pharmaceuticals, Inc. Two pellet controlled release formulation for water soluble drugs which contains an alkaline metal stearate
US6248361B1 (en) * 1999-02-26 2001-06-19 Integ, Ltd. Water-soluble folic acid compositions
US6248760B1 (en) * 1999-04-14 2001-06-19 Paul C Wilhelmsen Tablet giving rapid release of nicotine for transmucosal administration
DE19941997A1 (de) 1999-09-02 2001-03-08 Gunther Meinhardt Voss Verfahren und Vorrichtung zur Herstellung einer Tablette o. dgl.
US20020102309A1 (en) * 1999-09-14 2002-08-01 Jane C. I. Hirsh Controlled release formulation for administration of an anti-inflammatory naphthalene derivative
US20020028240A1 (en) * 2000-04-17 2002-03-07 Toyohiro Sawada Timed-release compression-coated solid composition for oral administration
US7122143B2 (en) * 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US20030066068A1 (en) * 2001-09-28 2003-04-03 Koninklijke Philips Electronics N.V. Individual recommender database using profiles of others
US6837696B2 (en) * 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
US6742646B2 (en) * 2001-09-28 2004-06-01 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US6982094B2 (en) * 2001-09-28 2006-01-03 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms

Also Published As

Publication number Publication date
NZ532095A (en) 2005-12-23
HUP0401653A2 (en) 2004-11-29
US20090186082A1 (en) 2009-07-23
CA2462008C (en) 2010-08-31
ZA200403166B (en) 2005-05-18
KR20040039458A (ko) 2004-05-10
AU2002337711B2 (en) 2008-06-05
KR100861670B1 (ko) 2008-10-07
ZA200403167B (en) 2005-05-27
MXPA04002971A (es) 2005-06-20
ES2319971T3 (es) 2009-05-18
CN100488763C (zh) 2009-05-20
US20050019376A1 (en) 2005-01-27
EP1429915B1 (de) 2009-01-14
ATE420762T1 (de) 2009-01-15
NO20041716L (no) 2004-04-27
CN1578724A (zh) 2005-02-09
CA2462008A1 (en) 2003-04-10
US6837696B2 (en) 2005-01-04
EP1429915A1 (de) 2004-06-23
PL369169A1 (en) 2005-04-18
CN1946378A (zh) 2007-04-11
US20030068367A1 (en) 2003-04-10
JP2005504639A (ja) 2005-02-17
WO2003028990A1 (en) 2003-04-10

Similar Documents

Publication Publication Date Title
DE60230886D1 (de) Systeme, verfahren und geräte zur herstellung von dosierungsformen
WO2003026615A3 (en) Modified release dosage forms
CY1111745T1 (el) Μεθοδος βιομηχανικης παρασκευης δισκιου
DE60132600D1 (de) Medikamente zur chemotherapeutischen behandlung von erkrankungen
DE60228464D1 (de) Wirkstoffabgabesysteme
ITRM20020264A0 (it) Articolo assorbente e procedimento per la sua fabbricazione.
DE50206657D1 (de) Pharmazeutische zusammensetzung zur behandlung von multiple sklerose
PT1439829E (pt) Medicamento contendo 3-(3-dimetilamino-1-etil-2-metilpropil)-fenol proporcionando libertacao retardada da substancia activa
DE60142473D1 (de) Intrakorporale medikamente zur photodynamischen behandlung von erkrankungen
DE60212663D1 (de) Dermales system zur wirkstoffabgabe
DE60210829D1 (de) Aufenthaltsortsregister, Aufenthaltsortsregistrierungssystem und -methode zur Reduzierung der Anzahl von Registrierungsnachrichten
ITTO20010283A0 (it) Composizione di erbe e procedimento di fabbricazione di tale composizione per il trattamento di disturbi ginecologici.
DE60143665D1 (de) Support-system zur herstellung von maschenware und entsprechendes server-system
WO2005009410A3 (en) Pharmaceutical compositions having a swellable coating
DE60141616D1 (de) Verfahren zur Herstellung von kleinen, sphärischen Siliconharzpartikeln
DE60228777D1 (de) Halbleiterbauelement vom Druckkontakttyp
IT1317478B1 (it) Procedimento per la manipolazione e il trasferimento di forme per ilmontaggio di calzature.
PT1187612E (pt) Utilizacao do riluzole para o tratamento da esclerose multipla
NO20025964D0 (no) Ny interferon for behandling av multippel sklerose
ITTO20010026A0 (it) Iniettore di combustibile e metodo di relizzazione del medesimo.
ZA200204014B (en) Spray diffusers and mold for manufacture of same.
WO2002069911A3 (de) WIRKSTOFFKOMBINATIONEN AUS α-LIPONSÄURE UND BIOCHINONEN
IT1315020B1 (it) Dispositivo per la produzione di gabbie di armatura e relativoprocedimento.
IT1318844B1 (it) Dispositivo per la conservazione, preparazione e dosaggio di soluzionia preparazione estemporanea.
MXPA05003279A (es) Forma de dosis de liberacion modificada.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition