GB936386A - Pellets for supplying biologically active substances to ruminants - Google Patents

Pellets for supplying biologically active substances to ruminants

Info

Publication number
GB936386A
GB936386A GB1700/59A GB170059A GB936386A GB 936386 A GB936386 A GB 936386A GB 1700/59 A GB1700/59 A GB 1700/59A GB 170059 A GB170059 A GB 170059A GB 936386 A GB936386 A GB 936386A
Authority
GB
United Kingdom
Prior art keywords
core
biologically active
pellet
outer layer
sac
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1700/59A
Inventor
Douglas Stephenson
John Spence
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to GB1700/59A priority Critical patent/GB936386A/en
Priority to ES0254869A priority patent/ES254869A1/en
Priority to BE586453A priority patent/BE586453A/en
Priority to DEW27064A priority patent/DE1117825B/en
Priority to FR815805A priority patent/FR1289423A/en
Publication of GB936386A publication Critical patent/GB936386A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0068Rumen, e.g. rumen bolus
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K40/00Shaping or working-up of animal feeding-stuffs
    • A23K40/30Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
    • A23K40/35Making capsules specially adapted for ruminants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A pellet for administration to a ruminant to supply it with a biologically active substance for an extended period of time, said pellet having a density and weight which relatively permanently retains it in the rumeno-reticular sac of the animal after administration and lodgement in the sac and embodying a core of density at least 3.5 around which there is an outer layer containing the biologically active substance which is released from the pellet into the contents of the sac over the extended period of time. The core is preferably reduced iron and may be granulated with, e.g., 10% aqueous gelatine, starch mucilage or a solution of a resin. A metallic oxide such as cupric oxide may also be present. The outer layer may contain hormones, antibloat agents, antibiotics, anthelmintics, antihistaminics, systemic insecticides and trace elements such as cobalt, copper, manganese, molybdenum, iron, iodine, boron and vanadium. The core may be coated by dipping or moulding the outer layer around the core. Specification 866,924 is referred to.
GB1700/59A 1959-01-16 1959-01-16 Pellets for supplying biologically active substances to ruminants Expired GB936386A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB1700/59A GB936386A (en) 1959-01-16 1959-01-16 Pellets for supplying biologically active substances to ruminants
ES0254869A ES254869A1 (en) 1959-01-16 1960-01-11 Pellets for supplying biologically active substances to ruminants
BE586453A BE586453A (en) 1959-01-16 1960-01-12 Dragees to be administered to ruminants to make them absorb substances with biological action, and their preparation
DEW27064A DE1117825B (en) 1959-01-16 1960-01-15 Method of making tablets
FR815805A FR1289423A (en) 1959-01-16 1960-01-15 Pill coating for the administration of biological material to ruminants

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1700/59A GB936386A (en) 1959-01-16 1959-01-16 Pellets for supplying biologically active substances to ruminants

Publications (1)

Publication Number Publication Date
GB936386A true GB936386A (en) 1963-09-11

Family

ID=9726505

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1700/59A Expired GB936386A (en) 1959-01-16 1959-01-16 Pellets for supplying biologically active substances to ruminants

Country Status (5)

Country Link
BE (1) BE586453A (en)
DE (1) DE1117825B (en)
ES (1) ES254869A1 (en)
FR (1) FR1289423A (en)
GB (1) GB936386A (en)

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341417A (en) * 1965-07-14 1967-09-12 Edwin S Sinaiko Method of and means for diagnosis of ingested drugs with radio-opaque and other indicators
US3507952A (en) * 1968-12-20 1970-04-21 Smithkline Corp Sustained release bolus for animal husbandry
US3535419A (en) * 1965-12-15 1970-10-20 Syntex Corp Veterinary compositions and methods
US3541204A (en) * 1968-12-02 1970-11-17 Ian Ramsay Sibbald Encapsulated biologically active materials for feeding to ruminants and process for the production thereof
GB2155335A (en) * 1984-03-07 1985-09-25 Crb Virbac Sa Device for sustained release of medicinal substances
GB2196252A (en) * 1986-09-18 1988-04-27 London Pharmacy Innovation Pharmaceutical formulation
US4948589A (en) * 1988-12-29 1990-08-14 Showa Denko Kabushiki Kaisha Granular composition for ruminant
US5186937A (en) * 1985-06-07 1993-02-16 A.E.C. Societe De Chimie Organique Et Biologique Composition for feeding ruminants
US5190775A (en) * 1991-05-29 1993-03-02 Balchem Corporation Encapsulated bioactive substances
GB2297484A (en) * 1995-02-01 1996-08-07 William Leslie Porter A Ruminant Bolus Comprising Particulate Matter and a Rapidly Dissolving Binder
US6056992A (en) 1988-06-02 2000-05-02 Campbell Soup Company Encapsulated additives
WO2003026627A1 (en) * 2001-09-28 2003-04-03 Mcneil-Ppc, Inc. Composite dosage forms
US6837696B2 (en) 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
US6881482B2 (en) 2001-08-16 2005-04-19 Southwest Research Institute Microencapsulation using electromagnetic energy and core and shell materials with different dielectric constants and dissipation factors
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US7217381B2 (en) 2001-09-28 2007-05-15 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7807197B2 (en) 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
CN117717534A (en) * 2024-02-08 2024-03-19 中国农业大学 Coating preparation for rumen dissolution of ruminant after rumen bypass and application thereof

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1293952B (en) * 1963-08-07 1969-04-30 Diwag Chemische Fabriken Gmbh Process for the production of pharmaceutical preparations for oral use with protracted release of active substances
FR2461495A1 (en) * 1979-07-23 1981-02-06 Vincent Andre Oblate, anthelmintic, prolonged release tablet for ruminants - releases active cpd. over 5-7 days and controls helminths in grazing animals without danger of toxicity
US4564363A (en) * 1983-07-13 1986-01-14 Smithkline Beckman Corporation Delayed action assembly
FR2582909B1 (en) * 1985-06-07 1991-05-10 Aec Chim Organ Biolog PRODUCT FOR FEEDING RUMINANTS AND ITS PREPARATION.

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341417A (en) * 1965-07-14 1967-09-12 Edwin S Sinaiko Method of and means for diagnosis of ingested drugs with radio-opaque and other indicators
US3535419A (en) * 1965-12-15 1970-10-20 Syntex Corp Veterinary compositions and methods
US3541204A (en) * 1968-12-02 1970-11-17 Ian Ramsay Sibbald Encapsulated biologically active materials for feeding to ruminants and process for the production thereof
US3507952A (en) * 1968-12-20 1970-04-21 Smithkline Corp Sustained release bolus for animal husbandry
GB2155335A (en) * 1984-03-07 1985-09-25 Crb Virbac Sa Device for sustained release of medicinal substances
US5186937A (en) * 1985-06-07 1993-02-16 A.E.C. Societe De Chimie Organique Et Biologique Composition for feeding ruminants
GB2196252A (en) * 1986-09-18 1988-04-27 London Pharmacy Innovation Pharmaceutical formulation
US4938967A (en) * 1986-09-18 1990-07-03 London School Of Pharmacy Innovations Ltd. Pharmaceutical formulations
GB2196252B (en) * 1986-09-18 1990-10-17 London Pharmacy Innovation Gastric controlled-release dosage forms
US6056992A (en) 1988-06-02 2000-05-02 Campbell Soup Company Encapsulated additives
US4948589A (en) * 1988-12-29 1990-08-14 Showa Denko Kabushiki Kaisha Granular composition for ruminant
US6013286A (en) * 1991-05-29 2000-01-11 Balchem Corporation Encapsulated bioactive substances
US5190775A (en) * 1991-05-29 1993-03-02 Balchem Corporation Encapsulated bioactive substances
GB2297484B (en) * 1995-02-01 1998-06-10 William Leslie Porter Bolus for supplying biologically beneficial substances to ruminant animals
GB2297484A (en) * 1995-02-01 1996-08-07 William Leslie Porter A Ruminant Bolus Comprising Particulate Matter and a Rapidly Dissolving Binder
US6881482B2 (en) 2001-08-16 2005-04-19 Southwest Research Institute Microencapsulation using electromagnetic energy and core and shell materials with different dielectric constants and dissipation factors
US7217381B2 (en) 2001-09-28 2007-05-15 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US8673190B2 (en) 2001-09-28 2014-03-18 Mcneil-Ppc, Inc. Method for manufacturing dosage forms
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
WO2003026627A1 (en) * 2001-09-28 2003-04-03 Mcneil-Ppc, Inc. Composite dosage forms
US6837696B2 (en) 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US7968120B2 (en) 2001-09-28 2011-06-28 Mcneil-Ppc, Inc. Modified release dosage forms
US7972624B2 (en) 2001-09-28 2011-07-05 Shun-Por Li Method of manufacturing modified release dosage forms
US8114328B2 (en) 2001-09-28 2012-02-14 Mcneil-Ppc, Inc. Method of coating a dosage form comprising a first medicant
US8545887B2 (en) 2001-09-28 2013-10-01 Mcneil-Ppc, Inc. Modified release dosage forms
US7807197B2 (en) 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
CN117717534A (en) * 2024-02-08 2024-03-19 中国农业大学 Coating preparation for rumen dissolution of ruminant after rumen bypass and application thereof
CN117717534B (en) * 2024-02-08 2024-04-19 中国农业大学 Coating preparation for rumen dissolution of ruminant after rumen bypass and application thereof

Also Published As

Publication number Publication date
FR1289423A (en) 1962-04-06
ES254869A1 (en) 1960-09-01
BE586453A (en) 1960-07-12
DE1117825B (en) 1961-11-23

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