ES254869A1 - Pellets for supplying biologically active substances to ruminants - Google Patents

Pellets for supplying biologically active substances to ruminants

Info

Publication number
ES254869A1
ES254869A1 ES0254869A ES254869A ES254869A1 ES 254869 A1 ES254869 A1 ES 254869A1 ES 0254869 A ES0254869 A ES 0254869A ES 254869 A ES254869 A ES 254869A ES 254869 A1 ES254869 A1 ES 254869A1
Authority
ES
Spain
Prior art keywords
core
biologically active
pellet
outer layer
sac
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0254869A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of ES254869A1 publication Critical patent/ES254869A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0068—Rumen, e.g. rumen bolus
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/30—Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
    • A23K40/35—Making capsules specially adapted for ruminants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Abstract

A pellet for administration to a ruminant to supply it with a biologically active substance for an extended period of time, said pellet having a density and weight which relatively permanently retains it in the rumeno-reticular sac of the animal after administration and lodgement in the sac and embodying a core of density at least 3.5 around which there is an outer layer containing the biologically active substance which is released from the pellet into the contents of the sac over the extended period of time. The core is preferably reduced iron and may be granulated with, e.g., 10% aqueous gelatine, starch mucilage or a solution of a resin. A metallic oxide such as cupric oxide may also be present. The outer layer may contain hormones, antibloat agents, antibiotics, anthelmintics, antihistaminics, systemic insecticides and trace elements such as cobalt, copper, manganese, molybdenum, iron, iodine, boron and vanadium. The core may be coated by dipping or moulding the outer layer around the core. Specification 866,924 is referred to.
ES0254869A 1959-01-16 1960-01-11 Pellets for supplying biologically active substances to ruminants Expired ES254869A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1700/59A GB936386A (en) 1959-01-16 1959-01-16 Pellets for supplying biologically active substances to ruminants

Publications (1)

Publication Number Publication Date
ES254869A1 true ES254869A1 (en) 1960-09-01

Family

ID=9726505

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0254869A Expired ES254869A1 (en) 1959-01-16 1960-01-11 Pellets for supplying biologically active substances to ruminants

Country Status (5)

Country Link
BE (1) BE586453A (en)
DE (1) DE1117825B (en)
ES (1) ES254869A1 (en)
FR (1) FR1289423A (en)
GB (1) GB936386A (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1293952B (en) * 1963-08-07 1969-04-30 Diwag Chemische Fabriken Gmbh Process for the production of pharmaceutical preparations for oral use with protracted release of active substances
US3341417A (en) * 1965-07-14 1967-09-12 Edwin S Sinaiko Method of and means for diagnosis of ingested drugs with radio-opaque and other indicators
US3535419A (en) * 1965-12-15 1970-10-20 Syntex Corp Veterinary compositions and methods
US3541204A (en) * 1968-12-02 1970-11-17 Ian Ramsay Sibbald Encapsulated biologically active materials for feeding to ruminants and process for the production thereof
US3507952A (en) * 1968-12-20 1970-04-21 Smithkline Corp Sustained release bolus for animal husbandry
FR2461495A1 (en) * 1979-07-23 1981-02-06 Vincent Andre Oblate, anthelmintic, prolonged release tablet for ruminants - releases active cpd. over 5-7 days and controls helminths in grazing animals without danger of toxicity
US4564363A (en) * 1983-07-13 1986-01-14 Smithkline Beckman Corporation Delayed action assembly
FR2560768A1 (en) * 1984-03-07 1985-09-13 Crb Virbac Sa PROGRAMMED RELEASE DEVICE
FR2582909B1 (en) * 1985-06-07 1991-05-10 Aec Chim Organ Biolog PRODUCT FOR FEEDING RUMINANTS AND ITS PREPARATION.
US5186937A (en) * 1985-06-07 1993-02-16 A.E.C. Societe De Chimie Organique Et Biologique Composition for feeding ruminants
ATE71293T1 (en) * 1986-09-18 1992-01-15 London Pharmacy Innovation DRUG FORMULATION.
US6056992A (en) 1988-06-02 2000-05-02 Campbell Soup Company Encapsulated additives
CA1331713C (en) * 1988-12-29 1994-08-30 Hitoshi Iijima Granular composition for ruminant
US5190775A (en) * 1991-05-29 1993-03-02 Balchem Corporation Encapsulated bioactive substances
GB2297484B (en) * 1995-02-01 1998-06-10 William Leslie Porter Bolus for supplying biologically beneficial substances to ruminant animals
US6881482B2 (en) 2001-08-16 2005-04-19 Southwest Research Institute Microencapsulation using electromagnetic energy and core and shell materials with different dielectric constants and dissipation factors
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US7217381B2 (en) 2001-09-28 2007-05-15 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
ATE404179T1 (en) * 2001-09-28 2008-08-15 Mcneil Ppc Inc DOSAGE FORMS WITH CORE AND OUTER SHELL
US6837696B2 (en) 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US7807197B2 (en) 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form

Also Published As

Publication number Publication date
FR1289423A (en) 1962-04-06
DE1117825B (en) 1961-11-23
GB936386A (en) 1963-09-11
BE586453A (en) 1960-07-12

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