DE60202682T2 - Chinoline derivate und ihre anwendung als antitumor agentien - Google Patents
Chinoline derivate und ihre anwendung als antitumor agentien Download PDFInfo
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- DE60202682T2 DE60202682T2 DE60202682T DE60202682T DE60202682T2 DE 60202682 T2 DE60202682 T2 DE 60202682T2 DE 60202682 T DE60202682 T DE 60202682T DE 60202682 T DE60202682 T DE 60202682T DE 60202682 T2 DE60202682 T2 DE 60202682T2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30914401P | 2001-07-31 | 2001-07-31 | |
| US309144P | 2001-07-31 | ||
| PCT/US2002/024442 WO2003011832A1 (en) | 2001-07-31 | 2002-07-31 | Quinoline derivatives and use thereof as antitumor agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60202682D1 DE60202682D1 (de) | 2005-02-24 |
| DE60202682T2 true DE60202682T2 (de) | 2005-12-29 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60202682T Expired - Lifetime DE60202682T2 (de) | 2001-07-31 | 2002-07-31 | Chinoline derivate und ihre anwendung als antitumor agentien |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US6867219B2 (enExample) |
| EP (1) | EP1412332B1 (enExample) |
| JP (1) | JP4310185B2 (enExample) |
| KR (1) | KR20040055774A (enExample) |
| AT (1) | ATE287397T1 (enExample) |
| AU (1) | AU2002355747B2 (enExample) |
| CA (1) | CA2456173A1 (enExample) |
| DE (1) | DE60202682T2 (enExample) |
| DK (1) | DK1412332T3 (enExample) |
| EA (1) | EA007205B1 (enExample) |
| ES (1) | ES2236548T3 (enExample) |
| GE (1) | GEP20063754B (enExample) |
| HU (1) | HUP0401562A2 (enExample) |
| IL (2) | IL160082A0 (enExample) |
| MX (1) | MXPA04000968A (enExample) |
| NO (1) | NO326463B1 (enExample) |
| NZ (1) | NZ530806A (enExample) |
| PL (1) | PL367340A1 (enExample) |
| PT (1) | PT1412332E (enExample) |
| UA (1) | UA75691C2 (enExample) |
| WO (1) | WO2003011832A1 (enExample) |
| ZA (1) | ZA200401185B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2401778C (en) * | 2000-02-29 | 2010-12-21 | Cor Therapeutics, Inc. | Benzamides and related inhibitors of factor xa |
| KR20040055774A (ko) * | 2001-07-31 | 2004-06-26 | 웨인 스테이트 유니버시티 | 퀴놀린 유도체 및 항종양제로서 그의 용도 |
| UA79293C2 (en) * | 2002-07-03 | 2007-06-11 | Univ Wayne State | 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents |
| CN1678310A (zh) * | 2002-08-24 | 2005-10-05 | 赞塔里斯有限公司 | 用于治疗良性和恶性肿瘤疾病的含有disorazole及其衍生物的药物 |
| US20070054938A1 (en) * | 2005-09-07 | 2007-03-08 | Horwitz Jerome P | Antitumor agents |
| US8183379B2 (en) * | 2005-09-07 | 2012-05-22 | Wayne State University | Antitumor agents |
| US7470788B2 (en) * | 2005-09-07 | 2008-12-30 | Wayne State University | Antitumor agents |
| EP1897542A1 (en) * | 2006-09-07 | 2008-03-12 | Sanofi-Aventis | Aqueous formulation comprising an antitumor agent |
| JO2685B1 (en) * | 2006-12-06 | 2013-03-03 | جانسين فارماسوتيكا ان في | Quinoline antibacterial derivatives |
| WO2009002955A1 (en) * | 2007-06-27 | 2008-12-31 | Sanofi-Aventis U.S. Llc | Process for the preparation of (2r)-2-[4-(7-bromo-2-quinolyloxy)phenoxy]propanoic acid |
| JP2014516075A (ja) | 2011-06-06 | 2014-07-07 | シェブロン フィリップス ケミカル カンパニー エルピー | 癌治療のためのメタロセン化合物の使用 |
| EP4583874A1 (en) * | 2022-12-21 | 2025-07-16 | Charles University, Faculty Of Pharmacy In Hradec Kralove | Multitarget nuclear receptor ligands based on 2-(4-(quinolin-2-yloxy)phenoxy)propanoic acid and 2-(4-(quinoxalin-2-yloxy)phenoxy)propanoic acid for the treatment of metabolic and liver diseases |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6033389B2 (ja) | 1979-02-22 | 1985-08-02 | 日産化学工業株式会社 | 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤 |
| US5364831A (en) * | 1980-08-06 | 1994-11-15 | Nissan Chemical Industries Ltd. | Quinoxaline derivatives and herbicidal composition |
| US6197728B1 (en) * | 1980-08-06 | 2001-03-06 | Nissan Chemical Industries Ltd. | Quinoxaline derivatives and herbicidal composition |
| US5250690A (en) * | 1985-05-02 | 1993-10-05 | Dowelanco | Haloalkoxy anilide derivatives of 2-4(-heterocyclic oxyphenoxy)alkanoic or alkenoic acids and their use as herbicides |
| KR20040055774A (ko) * | 2001-07-31 | 2004-06-26 | 웨인 스테이트 유니버시티 | 퀴놀린 유도체 및 항종양제로서 그의 용도 |
| UA79293C2 (en) * | 2002-07-03 | 2007-06-11 | Univ Wayne State | 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents |
| US7470788B2 (en) * | 2005-09-07 | 2008-12-30 | Wayne State University | Antitumor agents |
-
2002
- 2002-07-31 KR KR10-2004-7001559A patent/KR20040055774A/ko not_active Abandoned
- 2002-07-31 GE GE5486A patent/GEP20063754B/en unknown
- 2002-07-31 UA UA2004021374A patent/UA75691C2/uk unknown
- 2002-07-31 WO PCT/US2002/024442 patent/WO2003011832A1/en not_active Ceased
- 2002-07-31 US US10/210,781 patent/US6867219B2/en not_active Expired - Lifetime
- 2002-07-31 EA EA200400219A patent/EA007205B1/ru not_active IP Right Cessation
- 2002-07-31 EP EP02752656A patent/EP1412332B1/en not_active Expired - Lifetime
- 2002-07-31 HU HU0401562A patent/HUP0401562A2/hu unknown
- 2002-07-31 PT PT02752656T patent/PT1412332E/pt unknown
- 2002-07-31 JP JP2003517024A patent/JP4310185B2/ja not_active Expired - Fee Related
- 2002-07-31 IL IL16008202A patent/IL160082A0/xx unknown
- 2002-07-31 AU AU2002355747A patent/AU2002355747B2/en not_active Ceased
- 2002-07-31 PL PL02367340A patent/PL367340A1/xx not_active Application Discontinuation
- 2002-07-31 DE DE60202682T patent/DE60202682T2/de not_active Expired - Lifetime
- 2002-07-31 AT AT02752656T patent/ATE287397T1/de not_active IP Right Cessation
- 2002-07-31 MX MXPA04000968A patent/MXPA04000968A/es active IP Right Grant
- 2002-07-31 ES ES02752656T patent/ES2236548T3/es not_active Expired - Lifetime
- 2002-07-31 DK DK02752656T patent/DK1412332T3/da active
- 2002-07-31 NZ NZ530806A patent/NZ530806A/en unknown
- 2002-07-31 CA CA002456173A patent/CA2456173A1/en not_active Abandoned
-
2004
- 2004-01-27 IL IL160082A patent/IL160082A/en not_active IP Right Cessation
- 2004-01-28 NO NO20040382A patent/NO326463B1/no not_active IP Right Cessation
- 2004-02-13 ZA ZA200401185A patent/ZA200401185B/en unknown
- 2004-12-10 US US11/009,457 patent/US7241894B2/en not_active Expired - Fee Related
-
2007
- 2007-05-24 US US11/753,197 patent/US7507749B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60202682D1 (de) | 2005-02-24 |
| DK1412332T3 (da) | 2005-05-30 |
| WO2003011832A1 (en) | 2003-02-13 |
| EP1412332A1 (en) | 2004-04-28 |
| CA2456173A1 (en) | 2003-02-13 |
| EA200400219A1 (ru) | 2004-12-30 |
| PT1412332E (pt) | 2005-06-30 |
| US20050159447A1 (en) | 2005-07-21 |
| MXPA04000968A (es) | 2005-02-17 |
| PL367340A1 (en) | 2005-02-21 |
| NO326463B1 (no) | 2008-12-08 |
| AU2002355747B2 (en) | 2007-12-20 |
| EP1412332B1 (en) | 2005-01-19 |
| ZA200401185B (en) | 2004-10-21 |
| JP2004538314A (ja) | 2004-12-24 |
| IL160082A0 (en) | 2004-06-20 |
| US7241894B2 (en) | 2007-07-10 |
| NZ530806A (en) | 2006-05-26 |
| UA75691C2 (en) | 2006-05-15 |
| US20070232643A1 (en) | 2007-10-04 |
| US20030144321A1 (en) | 2003-07-31 |
| KR20040055774A (ko) | 2004-06-26 |
| JP4310185B2 (ja) | 2009-08-05 |
| HUP0401562A2 (hu) | 2004-12-28 |
| ES2236548T3 (es) | 2005-07-16 |
| US7507749B2 (en) | 2009-03-24 |
| NO20040382L (no) | 2004-03-26 |
| US6867219B2 (en) | 2005-03-15 |
| IL160082A (en) | 2009-06-15 |
| ATE287397T1 (de) | 2005-02-15 |
| GEP20063754B (en) | 2006-02-27 |
| EA007205B1 (ru) | 2006-08-25 |
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