DK1412332T3 - Quinolinderivater og anvendelse deraf som antitumormidler - Google Patents

Quinolinderivater og anvendelse deraf som antitumormidler

Info

Publication number
DK1412332T3
DK1412332T3 DK02752656T DK02752656T DK1412332T3 DK 1412332 T3 DK1412332 T3 DK 1412332T3 DK 02752656 T DK02752656 T DK 02752656T DK 02752656 T DK02752656 T DK 02752656T DK 1412332 T3 DK1412332 T3 DK 1412332T3
Authority
DK
Denmark
Prior art keywords
formula
compound
antitumor agents
quinoline derivatives
salt
Prior art date
Application number
DK02752656T
Other languages
English (en)
Inventor
Jerome P Horwitz
Stewart T Hazeldine
Thomas H Corbett
Lisa Polin
Original Assignee
Univ Wayne State
Jerome P Horwitz
Stewart T Hazeldine
Thomas H Corbett
Lisa Polin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wayne State, Jerome P Horwitz, Stewart T Hazeldine, Thomas H Corbett, Lisa Polin filed Critical Univ Wayne State
Application granted granted Critical
Publication of DK1412332T3 publication Critical patent/DK1412332T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
DK02752656T 2001-07-31 2002-07-31 Quinolinderivater og anvendelse deraf som antitumormidler DK1412332T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30914401P 2001-07-31 2001-07-31
PCT/US2002/024442 WO2003011832A1 (en) 2001-07-31 2002-07-31 Quinoline derivatives and use thereof as antitumor agents

Publications (1)

Publication Number Publication Date
DK1412332T3 true DK1412332T3 (da) 2005-05-30

Family

ID=23196886

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02752656T DK1412332T3 (da) 2001-07-31 2002-07-31 Quinolinderivater og anvendelse deraf som antitumormidler

Country Status (22)

Country Link
US (3) US6867219B2 (da)
EP (1) EP1412332B1 (da)
JP (1) JP4310185B2 (da)
KR (1) KR20040055774A (da)
AT (1) ATE287397T1 (da)
AU (1) AU2002355747B2 (da)
CA (1) CA2456173A1 (da)
DE (1) DE60202682T2 (da)
DK (1) DK1412332T3 (da)
EA (1) EA007205B1 (da)
ES (1) ES2236548T3 (da)
GE (1) GEP20063754B (da)
HU (1) HUP0401562A2 (da)
IL (2) IL160082A0 (da)
MX (1) MXPA04000968A (da)
NO (1) NO326463B1 (da)
NZ (1) NZ530806A (da)
PL (1) PL367340A1 (da)
PT (1) PT1412332E (da)
UA (1) UA75691C2 (da)
WO (1) WO2003011832A1 (da)
ZA (1) ZA200401185B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2254385T3 (es) * 2000-02-29 2006-06-16 Millennium Pharmaceuticals, Inc. Benzamidas e inhibidores relacionados del factor xa.
NZ530806A (en) * 2001-07-31 2006-05-26 Univ Wayne State Quinoline derivatives and use thereof as antitumor agents
UA79293C2 (en) * 2002-07-03 2007-06-11 Univ Wayne State 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents
AR042617A1 (es) * 2002-08-24 2005-06-29 Zentaris Gmbh Disorazoles y sus derivados, utiles para el tratamiento de enfermedades tumorales benignas y malignas, y el uso de dichos compuestos para la preparacion de medicamentos.
US20070054938A1 (en) * 2005-09-07 2007-03-08 Horwitz Jerome P Antitumor agents
US7470788B2 (en) 2005-09-07 2008-12-30 Wayne State University Antitumor agents
US8183379B2 (en) 2005-09-07 2012-05-22 Wayne State University Antitumor agents
EP1897542A1 (en) * 2006-09-07 2008-03-12 Sanofi-Aventis Aqueous formulation comprising an antitumor agent
JO2685B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
WO2009002955A1 (en) * 2007-06-27 2008-12-31 Sanofi-Aventis U.S. Llc Process for the preparation of (2r)-2-[4-(7-bromo-2-quinolyloxy)phenoxy]propanoic acid
WO2012170384A1 (en) 2011-06-06 2012-12-13 Chevron Phillips Chemical Company Lp Use of metallocene compounds for cancer treatment

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6033389B2 (ja) * 1979-02-22 1985-08-02 日産化学工業株式会社 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤
US5364831A (en) * 1980-08-06 1994-11-15 Nissan Chemical Industries Ltd. Quinoxaline derivatives and herbicidal composition
US6197728B1 (en) * 1980-08-06 2001-03-06 Nissan Chemical Industries Ltd. Quinoxaline derivatives and herbicidal composition
US5250690A (en) * 1985-05-02 1993-10-05 Dowelanco Haloalkoxy anilide derivatives of 2-4(-heterocyclic oxyphenoxy)alkanoic or alkenoic acids and their use as herbicides
NZ530806A (en) * 2001-07-31 2006-05-26 Univ Wayne State Quinoline derivatives and use thereof as antitumor agents
UA79293C2 (en) * 2002-07-03 2007-06-11 Univ Wayne State 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents
US7470788B2 (en) * 2005-09-07 2008-12-30 Wayne State University Antitumor agents

Also Published As

Publication number Publication date
ATE287397T1 (de) 2005-02-15
US7507749B2 (en) 2009-03-24
PT1412332E (pt) 2005-06-30
KR20040055774A (ko) 2004-06-26
US7241894B2 (en) 2007-07-10
US20070232643A1 (en) 2007-10-04
DE60202682D1 (de) 2005-02-24
ES2236548T3 (es) 2005-07-16
US20050159447A1 (en) 2005-07-21
WO2003011832A1 (en) 2003-02-13
US20030144321A1 (en) 2003-07-31
EP1412332B1 (en) 2005-01-19
PL367340A1 (en) 2005-02-21
MXPA04000968A (es) 2005-02-17
JP4310185B2 (ja) 2009-08-05
HUP0401562A2 (hu) 2004-12-28
NO20040382L (no) 2004-03-26
NO326463B1 (no) 2008-12-08
IL160082A (en) 2009-06-15
EA007205B1 (ru) 2006-08-25
US6867219B2 (en) 2005-03-15
ZA200401185B (en) 2004-10-21
AU2002355747B2 (en) 2007-12-20
EP1412332A1 (en) 2004-04-28
CA2456173A1 (en) 2003-02-13
IL160082A0 (en) 2004-06-20
DE60202682T2 (de) 2005-12-29
EA200400219A1 (ru) 2004-12-30
JP2004538314A (ja) 2004-12-24
NZ530806A (en) 2006-05-26
UA75691C2 (en) 2006-05-15
GEP20063754B (en) 2006-02-27

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