DK1412332T3 - Quinolinderivater og anvendelse deraf som antitumormidler - Google Patents
Quinolinderivater og anvendelse deraf som antitumormidlerInfo
- Publication number
- DK1412332T3 DK1412332T3 DK02752656T DK02752656T DK1412332T3 DK 1412332 T3 DK1412332 T3 DK 1412332T3 DK 02752656 T DK02752656 T DK 02752656T DK 02752656 T DK02752656 T DK 02752656T DK 1412332 T3 DK1412332 T3 DK 1412332T3
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- compound
- antitumor agents
- quinoline derivatives
- salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30914401P | 2001-07-31 | 2001-07-31 | |
PCT/US2002/024442 WO2003011832A1 (en) | 2001-07-31 | 2002-07-31 | Quinoline derivatives and use thereof as antitumor agents |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1412332T3 true DK1412332T3 (da) | 2005-05-30 |
Family
ID=23196886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02752656T DK1412332T3 (da) | 2001-07-31 | 2002-07-31 | Quinolinderivater og anvendelse deraf som antitumormidler |
Country Status (22)
Country | Link |
---|---|
US (3) | US6867219B2 (da) |
EP (1) | EP1412332B1 (da) |
JP (1) | JP4310185B2 (da) |
KR (1) | KR20040055774A (da) |
AT (1) | ATE287397T1 (da) |
AU (1) | AU2002355747B2 (da) |
CA (1) | CA2456173A1 (da) |
DE (1) | DE60202682T2 (da) |
DK (1) | DK1412332T3 (da) |
EA (1) | EA007205B1 (da) |
ES (1) | ES2236548T3 (da) |
GE (1) | GEP20063754B (da) |
HU (1) | HUP0401562A2 (da) |
IL (2) | IL160082A0 (da) |
MX (1) | MXPA04000968A (da) |
NO (1) | NO326463B1 (da) |
NZ (1) | NZ530806A (da) |
PL (1) | PL367340A1 (da) |
PT (1) | PT1412332E (da) |
UA (1) | UA75691C2 (da) |
WO (1) | WO2003011832A1 (da) |
ZA (1) | ZA200401185B (da) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE311366T1 (de) * | 2000-02-29 | 2005-12-15 | Millennium Pharm Inc | Benzamide und ähnliche inhibitoren vom faktor xa |
UA75691C2 (en) * | 2001-07-31 | 2006-05-15 | Univ Wayne State | Quinoline derivatives, use thereof as antitumor drugs, composition based thereon and therapeutical method for treatment of cancer |
UA79293C2 (en) * | 2002-07-03 | 2007-06-11 | Univ Wayne State | 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents |
JP2006500398A (ja) * | 2002-08-24 | 2006-01-05 | ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 良性及び悪性の腫瘍疾患を処置するためのジソラゾール及びその誘導体を含有している医薬 |
US20070054938A1 (en) * | 2005-09-07 | 2007-03-08 | Horwitz Jerome P | Antitumor agents |
US7470788B2 (en) | 2005-09-07 | 2008-12-30 | Wayne State University | Antitumor agents |
US8183379B2 (en) | 2005-09-07 | 2012-05-22 | Wayne State University | Antitumor agents |
EP1897542A1 (en) * | 2006-09-07 | 2008-03-12 | Sanofi-Aventis | Aqueous formulation comprising an antitumor agent |
JO2685B1 (en) * | 2006-12-06 | 2013-03-03 | جانسين فارماسوتيكا ان في | Quinoline antibacterial derivatives |
WO2009002955A1 (en) * | 2007-06-27 | 2008-12-31 | Sanofi-Aventis U.S. Llc | Process for the preparation of (2r)-2-[4-(7-bromo-2-quinolyloxy)phenoxy]propanoic acid |
WO2012170384A1 (en) | 2011-06-06 | 2012-12-13 | Chevron Phillips Chemical Company Lp | Use of metallocene compounds for cancer treatment |
WO2024132001A1 (en) * | 2022-12-21 | 2024-06-27 | Charles University, Faculty Of Pharmacy In Hradec Kralove | Multitarget nuclear receptor ligands based on 2-(4-(quinolin-2-yloxy)phenoxy)propanoic acid and 2-(4-(quinoxalin-2-yloxy)phenoxy)propanoic acid for the treatment of metabolic and liver diseases |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6033389B2 (ja) | 1979-02-22 | 1985-08-02 | 日産化学工業株式会社 | 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤 |
US6197728B1 (en) | 1980-08-06 | 2001-03-06 | Nissan Chemical Industries Ltd. | Quinoxaline derivatives and herbicidal composition |
US5364831A (en) | 1980-08-06 | 1994-11-15 | Nissan Chemical Industries Ltd. | Quinoxaline derivatives and herbicidal composition |
US5250690A (en) * | 1985-05-02 | 1993-10-05 | Dowelanco | Haloalkoxy anilide derivatives of 2-4(-heterocyclic oxyphenoxy)alkanoic or alkenoic acids and their use as herbicides |
UA75691C2 (en) * | 2001-07-31 | 2006-05-15 | Univ Wayne State | Quinoline derivatives, use thereof as antitumor drugs, composition based thereon and therapeutical method for treatment of cancer |
UA79293C2 (en) * | 2002-07-03 | 2007-06-11 | Univ Wayne State | 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents |
US7470788B2 (en) * | 2005-09-07 | 2008-12-30 | Wayne State University | Antitumor agents |
-
2002
- 2002-07-31 UA UA2004021374A patent/UA75691C2/uk unknown
- 2002-07-31 AT AT02752656T patent/ATE287397T1/de not_active IP Right Cessation
- 2002-07-31 DE DE60202682T patent/DE60202682T2/de not_active Expired - Lifetime
- 2002-07-31 CA CA002456173A patent/CA2456173A1/en not_active Abandoned
- 2002-07-31 WO PCT/US2002/024442 patent/WO2003011832A1/en active IP Right Grant
- 2002-07-31 MX MXPA04000968A patent/MXPA04000968A/es active IP Right Grant
- 2002-07-31 HU HU0401562A patent/HUP0401562A2/hu unknown
- 2002-07-31 EP EP02752656A patent/EP1412332B1/en not_active Expired - Lifetime
- 2002-07-31 NZ NZ530806A patent/NZ530806A/en unknown
- 2002-07-31 DK DK02752656T patent/DK1412332T3/da active
- 2002-07-31 IL IL16008202A patent/IL160082A0/xx unknown
- 2002-07-31 AU AU2002355747A patent/AU2002355747B2/en not_active Ceased
- 2002-07-31 KR KR10-2004-7001559A patent/KR20040055774A/ko active IP Right Grant
- 2002-07-31 ES ES02752656T patent/ES2236548T3/es not_active Expired - Lifetime
- 2002-07-31 GE GE5486A patent/GEP20063754B/en unknown
- 2002-07-31 EA EA200400219A patent/EA007205B1/ru not_active IP Right Cessation
- 2002-07-31 PT PT02752656T patent/PT1412332E/pt unknown
- 2002-07-31 US US10/210,781 patent/US6867219B2/en not_active Expired - Lifetime
- 2002-07-31 PL PL02367340A patent/PL367340A1/xx not_active Application Discontinuation
- 2002-07-31 JP JP2003517024A patent/JP4310185B2/ja not_active Expired - Fee Related
-
2004
- 2004-01-27 IL IL160082A patent/IL160082A/en not_active IP Right Cessation
- 2004-01-28 NO NO20040382A patent/NO326463B1/no not_active IP Right Cessation
- 2004-02-13 ZA ZA200401185A patent/ZA200401185B/en unknown
- 2004-12-10 US US11/009,457 patent/US7241894B2/en not_active Expired - Fee Related
-
2007
- 2007-05-24 US US11/753,197 patent/US7507749B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2456173A1 (en) | 2003-02-13 |
DE60202682D1 (de) | 2005-02-24 |
NO20040382L (no) | 2004-03-26 |
DE60202682T2 (de) | 2005-12-29 |
PL367340A1 (en) | 2005-02-21 |
MXPA04000968A (es) | 2005-02-17 |
US20030144321A1 (en) | 2003-07-31 |
WO2003011832A1 (en) | 2003-02-13 |
NZ530806A (en) | 2006-05-26 |
UA75691C2 (en) | 2006-05-15 |
US20050159447A1 (en) | 2005-07-21 |
EA200400219A1 (ru) | 2004-12-30 |
PT1412332E (pt) | 2005-06-30 |
KR20040055774A (ko) | 2004-06-26 |
IL160082A (en) | 2009-06-15 |
EP1412332B1 (en) | 2005-01-19 |
HUP0401562A2 (hu) | 2004-12-28 |
AU2002355747B2 (en) | 2007-12-20 |
ES2236548T3 (es) | 2005-07-16 |
US7507749B2 (en) | 2009-03-24 |
EP1412332A1 (en) | 2004-04-28 |
US20070232643A1 (en) | 2007-10-04 |
GEP20063754B (en) | 2006-02-27 |
ZA200401185B (en) | 2004-10-21 |
IL160082A0 (en) | 2004-06-20 |
NO326463B1 (no) | 2008-12-08 |
JP4310185B2 (ja) | 2009-08-05 |
US6867219B2 (en) | 2005-03-15 |
EA007205B1 (ru) | 2006-08-25 |
US7241894B2 (en) | 2007-07-10 |
JP2004538314A (ja) | 2004-12-24 |
ATE287397T1 (de) | 2005-02-15 |
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