ATE308540T1 - Antithrombosemittel - Google Patents
AntithrombosemittelInfo
- Publication number
- ATE308540T1 ATE308540T1 AT01961622T AT01961622T ATE308540T1 AT E308540 T1 ATE308540 T1 AT E308540T1 AT 01961622 T AT01961622 T AT 01961622T AT 01961622 T AT01961622 T AT 01961622T AT E308540 T1 ATE308540 T1 AT E308540T1
- Authority
- AT
- Austria
- Prior art keywords
- antithrombotic agents
- prodrug
- compound
- inhibitor
- factor
- Prior art date
Links
- 239000003146 anticoagulant agent Substances 0.000 title 1
- 229960004676 antithrombotic agent Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000651 prodrug Substances 0.000 abstract 2
- 229940002612 prodrug Drugs 0.000 abstract 2
- 108010074860 Factor Xa Proteins 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22592600P | 2000-08-17 | 2000-08-17 | |
| PCT/US2001/021130 WO2002014308A1 (en) | 2000-08-17 | 2001-08-06 | Antithrombotic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE308540T1 true ATE308540T1 (de) | 2005-11-15 |
Family
ID=22846837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01961622T ATE308540T1 (de) | 2000-08-17 | 2001-08-06 | Antithrombosemittel |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6924296B2 (de) |
| EP (1) | EP1311501B1 (de) |
| AT (1) | ATE308540T1 (de) |
| AU (1) | AU2001282871A1 (de) |
| DE (1) | DE60114640T2 (de) |
| ES (1) | ES2248380T3 (de) |
| WO (1) | WO2002014308A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7163938B2 (en) | 2000-11-28 | 2007-01-16 | Eli Lilly And Company | Substituted carboxamides |
| US20030050648A1 (en) * | 2001-09-11 | 2003-03-13 | Spiration, Inc. | Removable lung reduction devices, systems, and methods |
| EP1456175A1 (de) | 2001-12-07 | 2004-09-15 | Eli Lilly And Company | Substituierte heterozyklische karboxamide mit antithrombotischer aktivität |
| DE502004009440D1 (de) * | 2003-04-03 | 2009-06-10 | Merck Patent Gmbh | Pyrrolidin-1,2-dicarbonsäure-1-(phenylamid)-2-(4-(3-oxo-morpholin-4-yl)-phenylamid) derivate und verwandte verbindungen als inhibitoren des koagulationsfaktors xa zur behandlung von thromboembolischen erkrankungen |
| US20050119266A1 (en) * | 2003-10-01 | 2005-06-02 | Yan Shi | Pyrrolidine and piperidine derivatives as factor Xa inhibitors |
| JP5473334B2 (ja) * | 2005-12-23 | 2014-04-16 | ジーランド ファーマ アクティーゼルスカブ | 修飾リジン模倣化合物 |
| JP2009523553A (ja) * | 2006-01-17 | 2009-06-25 | ゾゲニクス インコーポレーティッド | 抗血栓薬の単回用量無針投与方法 |
| CN101616667A (zh) | 2006-10-27 | 2009-12-30 | 百时美施贵宝公司 | 可用作激酶抑制剂的杂环酰胺化合物 |
| CN101239937B (zh) * | 2007-02-07 | 2010-05-19 | 上海雅本化学有限公司 | 一种光学活性r-(-)-1-苄氧羰基-3-氨基吡咯烷及其盐酸盐的制备方法 |
| EP1975165A1 (de) * | 2007-03-27 | 2008-10-01 | Boehringer Ingelheim Pharma GmbH & Co. KG | Substituierte Pyrrolidinamide, deren Herstellung und deren Verwendung als Arzneimittel |
| RU2643336C1 (ru) * | 2016-10-03 | 2018-01-31 | Общество с Ограниченной Ответственностью "Компания "ЭЛТА" | СРЕДСТВО, ПРОЯВЛЯЮЩЕЕ АНТИТРОМБОТИЧЕСКИЙ ЭФФЕКТ ПОСРЕДСТВОМ БЛОКИРОВАНИЯ РЕЦЕПТОРОВ ТРОМБОЦИТОВ ГП IIb-IIIa (ВАРИАНТЫ) |
| SMT202400527T1 (it) | 2019-07-01 | 2025-01-14 | Tonix Pharma Ltd | Anticorpi anti-cd154 e loro usi |
| EP4274587A1 (de) | 2021-01-06 | 2023-11-15 | Tonix Pharma Limited | Verfahren zur induzierung von immuntoleranz mit modifizierten anti-cd154-antikörpern |
| WO2025248134A1 (en) | 2024-05-31 | 2025-12-04 | Tonix Pharma Limited | Treatment methods comprising administration of modified cd154 antibodies |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999000127A1 (en) | 1997-06-26 | 1999-01-07 | Eli Lilly And Company | Antithrombotic agents |
| ES2241151T3 (es) | 1997-06-26 | 2005-10-16 | Eli Lilly And Company | Agentes antitromboticos. |
| IL133621A0 (en) | 1997-06-26 | 2001-04-30 | Lilly Co Eli | Antithrombotic agents |
| EP0999834B1 (de) | 1997-06-26 | 2005-10-12 | Eli Lilly And Company | Antithrombosemittel |
| DE69931393T2 (de) | 1998-12-23 | 2007-03-29 | Eli Lilly And Co., Indianapolis | Antithrombotische amide |
| JP2002533454A (ja) * | 1998-12-23 | 2002-10-08 | イーライ・リリー・アンド・カンパニー | 芳香族アミド類 |
| AU2364600A (en) | 1998-12-23 | 2000-07-31 | Eli Lilly And Company | Heteroroaromatic amides as inhibitor of factor xa |
| CA2356214A1 (en) | 1998-12-24 | 2000-07-06 | Eli Lilly And Company | Heterocyclic amides as inhibitors of factor xa |
| WO2002010154A2 (en) | 2000-07-27 | 2002-02-07 | Eli Lilly And Company | Substituted heterocyclic amides |
-
2001
- 2001-08-06 AU AU2001282871A patent/AU2001282871A1/en not_active Abandoned
- 2001-08-06 ES ES01961622T patent/ES2248380T3/es not_active Expired - Lifetime
- 2001-08-06 DE DE60114640T patent/DE60114640T2/de not_active Expired - Fee Related
- 2001-08-06 US US10/333,624 patent/US6924296B2/en not_active Expired - Fee Related
- 2001-08-06 WO PCT/US2001/021130 patent/WO2002014308A1/en not_active Ceased
- 2001-08-06 AT AT01961622T patent/ATE308540T1/de not_active IP Right Cessation
- 2001-08-06 EP EP01961622A patent/EP1311501B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001282871A1 (en) | 2002-02-25 |
| US20040010017A1 (en) | 2004-01-15 |
| DE60114640D1 (en) | 2005-12-08 |
| EP1311501B1 (de) | 2005-11-02 |
| DE60114640T2 (de) | 2006-07-20 |
| ES2248380T3 (es) | 2006-03-16 |
| EP1311501A1 (de) | 2003-05-21 |
| WO2002014308A1 (en) | 2002-02-21 |
| US6924296B2 (en) | 2005-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |