ATE258934T1 - Azaindol derivate und ihre verwendung als antithrombotische wirkstoffe - Google Patents
Azaindol derivate und ihre verwendung als antithrombotische wirkstoffeInfo
- Publication number
- ATE258934T1 ATE258934T1 AT99308494T AT99308494T ATE258934T1 AT E258934 T1 ATE258934 T1 AT E258934T1 AT 99308494 T AT99308494 T AT 99308494T AT 99308494 T AT99308494 T AT 99308494T AT E258934 T1 ATE258934 T1 AT E258934T1
- Authority
- AT
- Austria
- Prior art keywords
- antithrbotic
- agents
- azaindole derivatives
- formula
- novel compounds
- Prior art date
Links
- BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical class C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229940122388 Thrombin inhibitor Drugs 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000003868 thrombin inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10641098P | 1998-10-30 | 1998-10-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE258934T1 true ATE258934T1 (de) | 2004-02-15 |
Family
ID=22311277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99308494T ATE258934T1 (de) | 1998-10-30 | 1999-10-27 | Azaindol derivate und ihre verwendung als antithrombotische wirkstoffe |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6265416B1 (de) |
| EP (1) | EP0997465B1 (de) |
| JP (1) | JP2000143663A (de) |
| AT (1) | ATE258934T1 (de) |
| CA (1) | CA2288386A1 (de) |
| DE (1) | DE69914563T2 (de) |
| ES (1) | ES2213984T3 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3868500A (en) * | 1999-03-10 | 2000-09-28 | Merck & Co., Inc. | 6-azaindole compounds as antagonists of gonadotropin releasing hormone |
| CN1745064A (zh) * | 2002-12-06 | 2006-03-08 | 泊达研究基金会 | 用于治疗受损的哺乳动物神经组织的吡啶 |
| US8729107B2 (en) * | 2002-12-06 | 2014-05-20 | Purdue Research Foundation | Pyridines for treating injured mammalian nerve tissue |
| KR102709050B1 (ko) * | 2019-11-08 | 2024-09-24 | 이화여자대학교 산학협력단 | 7-아자인돌 유도체를 포함하는 혈전성 질환의 예방 또는 치료용 약학 조성물 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5468757A (en) * | 1994-01-31 | 1995-11-21 | Eli Lilly And Company | 6-azaindole thromboxane synthase inhibitors |
| DE4426625A1 (de) | 1994-07-27 | 1996-03-14 | Schering Ag | 2-Phenylindole, Verfahren zu deren Herstellung, diese enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln |
| DE4435477A1 (de) | 1994-10-04 | 1996-04-11 | Bayer Ag | Cycloalkano-indol- und -azaindol-derivate |
| DE69634045T2 (de) | 1995-10-31 | 2005-05-19 | Eli Lilly And Co., Indianapolis | Antithrombotische diamine |
| ATE206701T1 (de) * | 1996-04-19 | 2001-10-15 | American Home Prod | Östrogene verbindungen |
| AU7170798A (en) * | 1997-04-30 | 1998-11-24 | Eli Lilly And Company | Antithrombotic agents |
-
1999
- 1999-10-27 AT AT99308494T patent/ATE258934T1/de not_active IP Right Cessation
- 1999-10-27 EP EP99308494A patent/EP0997465B1/de not_active Expired - Lifetime
- 1999-10-27 ES ES99308494T patent/ES2213984T3/es not_active Expired - Lifetime
- 1999-10-27 DE DE69914563T patent/DE69914563T2/de not_active Expired - Fee Related
- 1999-10-28 US US09/429,424 patent/US6265416B1/en not_active Expired - Fee Related
- 1999-10-29 JP JP11308814A patent/JP2000143663A/ja not_active Withdrawn
- 1999-10-29 CA CA002288386A patent/CA2288386A1/en not_active Abandoned
-
2000
- 2000-11-20 US US09/716,605 patent/US6359136B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6359136B1 (en) | 2002-03-19 |
| EP0997465B1 (de) | 2004-02-04 |
| JP2000143663A (ja) | 2000-05-26 |
| US6265416B1 (en) | 2001-07-24 |
| ES2213984T3 (es) | 2004-09-01 |
| DE69914563T2 (de) | 2004-12-16 |
| CA2288386A1 (en) | 2000-04-30 |
| EP0997465A1 (de) | 2000-05-03 |
| DE69914563D1 (de) | 2004-03-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |