DE69914563D1 - Azaindol derivate und ihre Verwendung als antithrombotische Wirkstoffe - Google Patents

Azaindol derivate und ihre Verwendung als antithrombotische Wirkstoffe

Info

Publication number
DE69914563D1
DE69914563D1 DE69914563T DE69914563T DE69914563D1 DE 69914563 D1 DE69914563 D1 DE 69914563D1 DE 69914563 T DE69914563 T DE 69914563T DE 69914563 T DE69914563 T DE 69914563T DE 69914563 D1 DE69914563 D1 DE 69914563D1
Authority
DE
Germany
Prior art keywords
antithrombotic agents
azaindole derivatives
formula
novel compounds
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69914563T
Other languages
English (en)
Other versions
DE69914563T2 (de
Inventor
Jolie Anne Bastian
Matthew Joseph Fisher
Richard Waltz Harper
Ho-Shen Lin
Jefferson Ray Mccowan
Daniel Jon Sall
Gerald Floyd Smith
Kumiko Takeuchi
Michael Robert Wiley
Minsheng Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE69914563D1 publication Critical patent/DE69914563D1/de
Application granted granted Critical
Publication of DE69914563T2 publication Critical patent/DE69914563T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
DE69914563T 1998-10-30 1999-10-27 Azaindol derivate und ihre Verwendung als antithrombotische Wirkstoffe Expired - Fee Related DE69914563T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10641098P 1998-10-30 1998-10-30
US106410P 1998-10-30

Publications (2)

Publication Number Publication Date
DE69914563D1 true DE69914563D1 (de) 2004-03-11
DE69914563T2 DE69914563T2 (de) 2004-12-16

Family

ID=22311277

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69914563T Expired - Fee Related DE69914563T2 (de) 1998-10-30 1999-10-27 Azaindol derivate und ihre Verwendung als antithrombotische Wirkstoffe

Country Status (7)

Country Link
US (2) US6265416B1 (de)
EP (1) EP0997465B1 (de)
JP (1) JP2000143663A (de)
AT (1) ATE258934T1 (de)
CA (1) CA2288386A1 (de)
DE (1) DE69914563T2 (de)
ES (1) ES2213984T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002539124A (ja) * 1999-03-10 2002-11-19 メルク エンド カムパニー インコーポレーテッド 性腺刺激ホルモン放出ホルモン拮抗薬としての６−アザインドール化合物
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
CN1745064A (zh) * 2002-12-06 2006-03-08 泊达研究基金会 用于治疗受损的哺乳动物神经组织的吡啶

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5468757A (en) * 1994-01-31 1995-11-21 Eli Lilly And Company 6-azaindole thromboxane synthase inhibitors
DE4426625A1 (de) 1994-07-27 1996-03-14 Schering Ag 2-Phenylindole, Verfahren zu deren Herstellung, diese enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
DE4435477A1 (de) 1994-10-04 1996-04-11 Bayer Ag Cycloalkano-indol- und -azaindol-derivate
JP2002500618A (ja) 1995-10-31 2002-01-08 イーライ・リリー・アンド・カンパニー 抗血栓性ジアミン
SK281737B6 (sk) * 1996-04-19 2001-07-10 American Home Products Corporation 2-fenylindolové zlúčeniny, farmaceutický prostriedok s ich obsahom a ich použitie
EP1011666A4 (de) * 1997-04-30 2004-03-31 Lilly Co Eli Antithrombotische mittel

Also Published As

Publication number Publication date
JP2000143663A (ja) 2000-05-26
US6359136B1 (en) 2002-03-19
US6265416B1 (en) 2001-07-24
ES2213984T3 (es) 2004-09-01
EP0997465A1 (de) 2000-05-03
CA2288386A1 (en) 2000-04-30
DE69914563T2 (de) 2004-12-16
ATE258934T1 (de) 2004-02-15
EP0997465B1 (de) 2004-02-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee