ATE242246T1 - (1,2,3)-triazolo(4,5-d)pyrimidin-derivate als antithrombotische mittel - Google Patents
(1,2,3)-triazolo(4,5-d)pyrimidin-derivate als antithrombotische mittelInfo
- Publication number
- ATE242246T1 ATE242246T1 AT00976525T AT00976525T ATE242246T1 AT E242246 T1 ATE242246 T1 AT E242246T1 AT 00976525 T AT00976525 T AT 00976525T AT 00976525 T AT00976525 T AT 00976525T AT E242246 T1 ATE242246 T1 AT E242246T1
- Authority
- AT
- Austria
- Prior art keywords
- triazolo
- antithrbotic
- agents
- pyrimidine derivatives
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9904129A SE9904129D0 (sv) | 1999-11-15 | 1999-11-15 | Novel compounds |
PCT/SE2000/002229 WO2001036421A1 (en) | 1999-11-15 | 2000-11-14 | Novel [1,2,3]-triazolo[4,5-d]pyrimidine compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE242246T1 true ATE242246T1 (de) | 2003-06-15 |
Family
ID=20417726
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00976525T ATE242246T1 (de) | 1999-11-15 | 2000-11-14 | (1,2,3)-triazolo(4,5-d)pyrimidin-derivate als antithrombotische mittel |
Country Status (8)
Country | Link |
---|---|
US (1) | US6713483B1 (de) |
EP (1) | EP1232156B1 (de) |
JP (1) | JP4859321B2 (de) |
AT (1) | ATE242246T1 (de) |
AU (1) | AU1428801A (de) |
DE (1) | DE60003220T2 (de) |
SE (1) | SE9904129D0 (de) |
WO (1) | WO2001036421A1 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0013488D0 (en) * | 2000-06-02 | 2000-07-26 | Astrazeneca Ab | Chemical compound |
GB0013407D0 (en) * | 2000-06-02 | 2000-07-26 | Astrazeneca Ab | Forms of a chemical compound |
US7018985B1 (en) | 2000-08-21 | 2006-03-28 | Inspire Pharmaceuticals, Inc. | Composition and method for inhibiting platelet aggregation |
US7115585B2 (en) | 2000-08-21 | 2006-10-03 | Inspire Pharmaceuticals, Inc. | Compositions for treating epithelial and retinal tissue diseases |
US6897201B2 (en) | 2000-08-21 | 2005-05-24 | Inspire Pharmaceuticals, Inc. | Compositions and methods for the treatment of glaucoma or ocular hypertension |
US7452870B2 (en) | 2000-08-21 | 2008-11-18 | Inspire Pharmaceuticals, Inc. | Drug-eluting stents coated with P2Y12 receptor antagonist compound |
US7132408B2 (en) | 2000-08-21 | 2006-11-07 | Inspire Pharmaceuticals, Inc. | Composition and method for inhibiting platelet aggregation |
US7435724B2 (en) | 2002-02-27 | 2008-10-14 | Inspire Pharmaceutical, Inc. | Degradation-resistant mononucleoside phosphate compounds |
EP1598354A1 (de) | 2004-05-18 | 2005-11-23 | Vasopharm Biotech GmbH | Durch kondensierten zyklus verbundenen n-heteroaryl verbindungen und ihre verwendung als nad(p)h oxidase und blutplättchen-aggregation hemmer |
GB0512844D0 (en) * | 2005-06-23 | 2005-08-03 | Novartis Ag | Organic compounds |
WO2007020935A1 (ja) * | 2005-08-17 | 2007-02-22 | Ono Pharmaceutical Co., Ltd. | P2y12受容体および/またはp2y14受容体ブロッカーを含有してなる疼痛治療剤 |
TWI482772B (zh) | 2006-08-21 | 2015-05-01 | Astrazeneca Ab | 適合口服且包含三唑并[4,5-d]嘧啶衍生物之組合物 |
US7566722B2 (en) * | 2006-10-31 | 2009-07-28 | Janssen Pharmaceutica, N.V. | Triazolopyrimidine derivatives as ADP P2Y12 receptor antagonists |
WO2012063126A2 (en) * | 2010-11-09 | 2012-05-18 | Actavis Group Ptc Ehf | Improved processes for preparing pure (3ar,4s,6r,6as)-6-amino-2,2-dimethyltetrahdro-3ah-cyclopenta[d] [1,3]-dioxol-4-ol and its key starting material |
HUE031673T2 (en) | 2011-09-14 | 2017-07-28 | Lek Pharmaceuticals | Synthesis of triazolopyrimidine compounds |
EP2570405A1 (de) * | 2011-09-14 | 2013-03-20 | LEK Pharmaceuticals d.d. | Synthese von Triazolpyrimidin-Verbindungen |
CN102603751A (zh) * | 2012-02-24 | 2012-07-25 | 中国药科大学 | 三唑并(4,5-d)嘧啶衍生物及其制备方法与在制药中的用途 |
WO2014206187A1 (zh) | 2013-06-24 | 2014-12-31 | 苏州明锐医药科技有限公司 | 替卡格雷及其中间体的制备方法 |
JP6145574B2 (ja) * | 2013-06-27 | 2017-06-14 | スーヂョウ ミラクファーマ テクノロジ カンパニー リミテッドSuzhou Miracpharma Technology Co.,Ltd. | チカグレロールの調製方法 |
CN105272985B (zh) * | 2014-06-24 | 2017-11-21 | 珠海联邦制药股份有限公司 | 三唑并[4,5‑d]嘧啶化合物及其合成方法、用途、组合物 |
CN112915063B (zh) * | 2021-01-25 | 2022-12-20 | 刘红枚 | 一种用于治疗子宫平滑肌高频率强直性收缩相关疾病的化合物 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0840740B1 (de) * | 1995-07-11 | 2002-05-02 | AstraZeneca AB | Inhibitoren der plättchenaggregation |
WO1998028300A1 (en) * | 1996-12-20 | 1998-07-02 | Astra Pharmaceuticals Ltd. | Triazolo[4,5-d]pyrimidinyl derivatives and their use as medicaments |
SE9702774D0 (sv) * | 1997-07-22 | 1997-07-22 | Astra Pharma Prod | Novel compounds |
SE9702772D0 (sv) * | 1997-07-22 | 1997-07-22 | Astra Pharma Prod | Novel compounds |
AR017014A1 (es) * | 1997-07-22 | 2001-08-22 | Astrazeneca Ab | Compuestos de triazolo [4,5-d]pirimidina, composiciones farmaceuticas, uso de los mismos para preparar medicamentos y procesos para la preparacionde dichos compuestos |
DE69905451T2 (de) | 1998-02-17 | 2003-11-20 | Astrazeneca Uk Ltd | Neue triazolo(4,5d) pyrimidinverbindungen |
SE9802574D0 (sv) | 1998-07-17 | 1998-07-17 | Astra Pharma Prod | Novel compounds |
TWI229674B (en) | 1998-12-04 | 2005-03-21 | Astra Pharma Prod | Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses |
-
1999
- 1999-11-15 SE SE9904129A patent/SE9904129D0/xx unknown
-
2000
- 2000-11-14 AU AU14288/01A patent/AU1428801A/en not_active Abandoned
- 2000-11-14 JP JP2001538910A patent/JP4859321B2/ja not_active Expired - Fee Related
- 2000-11-14 EP EP00976525A patent/EP1232156B1/de not_active Expired - Lifetime
- 2000-11-14 AT AT00976525T patent/ATE242246T1/de not_active IP Right Cessation
- 2000-11-14 WO PCT/SE2000/002229 patent/WO2001036421A1/en active IP Right Grant
- 2000-11-14 US US10/130,194 patent/US6713483B1/en not_active Expired - Lifetime
- 2000-11-14 DE DE60003220T patent/DE60003220T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE60003220D1 (de) | 2003-07-10 |
EP1232156B1 (de) | 2003-06-04 |
SE9904129D0 (sv) | 1999-11-15 |
EP1232156A1 (de) | 2002-08-21 |
JP4859321B2 (ja) | 2012-01-25 |
JP2003514819A (ja) | 2003-04-22 |
AU1428801A (en) | 2001-05-30 |
WO2001036421A1 (en) | 2001-05-25 |
US6713483B1 (en) | 2004-03-30 |
DE60003220T2 (de) | 2004-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |